UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	M106.2	M106.2	0	chrII 10,847,185	contains similarity to Homo sapiens Lamin B2; ENSEMBL:ENSP00000264564
2	C05D9.7	C05D9.7	n/a	chrX 1,118,323
3	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
4	C05D12.5	C05D12.5	n/a	chrII 11,434,516	contains similarity to Homo sapiens Isoform 1 of Cingulin-like protein 1; ENSEMBL:ENSP00000281282
5	EEED8.2	EEED8.2	n/a	chrII 5,417,509	contains similarity to Interpro domains IPR012674 (Calycin), IPR011038 (Calycin-like), IPR000463 (Cytosolic fatty-acid binding)
6	C24H12.1	C24H12.1	n/a	chrII 444,212	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
7	F58E1.12	F58E1.12	n/a	chrII 1,693,958
8	F42H10.2	F42H10.2	n/a	chrIII 8,490,759	contains similarity to Pfam domain PF06747 CHCH domain contains similarity to Interpro domains IPR010625 (CHCH), IPR013032 (EGF-like region, conserved site)
9	K08H2.4	K08H2.4	n/a	chrX 13,239,283
10	C24H12.8	C24H12.8	n/a	chrII 422,729	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
11	F19D8.2	F19D8.2	n/a	chrX 13,835,397	contains similarity to Homo sapiens Splice isoform 1 of Q9UMN6 Myeloid/lymphoid or mixed-lineage leukemia protein 4; ENSEMBL:ENSP00000222270
12	fbxb-103	F53C3.2	n/a	chrII 3,907,716	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
13	ZK673.5	ZK673.5	n/a	chrII 10,461,630	contains similarity to Interpro domain IPR001621 (Fungal lignin peroxidase)
14	dsl-1	W09G12.4	n/a	chrIV 1,207,661	dsl-1 encodes a secreted protein with a single DSL and EGF domain in series, resembling Delta/LAG-2; DSL-1, with APX-1 and LAG-2, is collectively required for LIN-12/Notch-mediated lateral signalling during postembryonic vulval development; DSL-1, when misexpressed by lag-2 sequences, can rescue the larval-lethal and anchor cell phenotypes of lag-2(q420ts); dsl-1(RNAi) animals have abnormal vulvae in a genetic background sensitized for lateral signalling defects; dsl-1(ok810) mutants, while viable and fertile, have a 4% penetrant defect in lateral signaling, which exceeds 13% with apx-1 and lag-2 RNAi; dsl-1 is strongly transcribed in P6.p cells; SUR-2 regulates dsl-1 along with apx-1 and lag-2; DSL-1 belongs to a nematode-specific family of Delta/LAG-2-like proteins that includes DSL-2, -3, -5, -6, and -7.
15	Y75B12A.2	Y75B12A.2	n/a	chrV 15,109,937	contains similarity to Saccharomyces cerevisiae Required for invasion and pseudohyphae formation in response to nitrogen starvation; SGD:YIR019C
16	F31E8.4	F31E8.4	n/a	chrII 6,799,569	contains similarity to Pfam domain PF04145 Ctr copper transporter family contains similarity to Interpro domain IPR007274 (Ctr copper transporter)
17	K02E10.1	K02E10.1	n/a	chrX 2,498,552	contains similarity to Pfam domains PF00071 (Ras family) , PF08477 (Miro-like protein) contains similarity to Interpro domains IPR002041 (Ran GTPase), IPR003577 (Ras small GTPase, Ras type), IPR013684 (Miro-like), IPR003578 (Ras small GTPase, Rho type), IPR005225 (Small GTP-binding protein), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR006688 (ADP-ribosylation factor), IPR013753 (Ras)
18	Y73C8C.3	Y73C8C.3	n/a	chrV 3,116,714	contains similarity to Homo sapiens Isoform 3 of Centromeric protein E; ENSEMBL:ENSP00000369365
19	ndx-6	EEED8.8	n/a	chrII 5,389,360	The ndx-6 gene encodes a NUDIX hydrolase.
20	C24H12.6	C24H12.6	n/a	chrII 418,114
21	Y54G11A.11	Y54G11A.11	n/a	chrII 14,350,230	contains similarity to Pfam domain PF05129 Transcription elongation factor Elf1 like contains similarity to Interpro domain IPR007808 (Protein of unknown function DUF701, zinc-binding putative)
22	F45D3.1	F45D3.1	n/a	chrV 12,527,844	contains similarity to Schizosaccharomyces pombe Hypothetical 92.4 kDa protein C1685.14C in chromosome II.; TR:O74334
23	W04H10.2	W04H10.2	n/a	chrII 606,109
24	cki-1	T05A6.1	n/a	chrII 7,811,601	cki-1 encodes a homolog of the mammalian cyclin-dependent kinase inhibitor p27/KIP1 that is required for the arrest of cell division in larval blast lineages, dauer larvae and starved L1 larvae; excess CKI-1 expression prematurely stops cell division while cki-1(RNAi) induces extra cell divisions, indicating that CKI-1 quantitatively regulates the amount of mitosis in postembryonic worms.
25	evl-20	F22B5.1	n/a	chrII 8,444,637	evl-20 encodes a functional ortholog of human ADP-ribosylation factor-like protein 2 (ARL2; OMIM:601175), with evl-20(ar103) mutants being rescued by transgenic human ARL2 but not ARL1 or ARL3-7; EVL-20 is required for cortical microtubule formation during cytokinesis and morphogenesis; EVL-20 is required for vulval, gonadal, and male tail development, as well as for embryonic mitosis, hypodermal enclosure, and elongation; EVL-20 is expressed in migrating hypodermal embryonic cells, larval vulval and somatic gonad cells, larval and adult neurons, and adult male proctodeal cells, being subcellularly associated with both the cell cortex and astral microtubules.
26	T18D3.1	T18D3.1	n/a	chrX 12,456,267	contains similarity to Interpro domains IPR000009 (Protein phosphatase 2A, regulatory subunit PR55), IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
27	K01A2.9	K01A2.9	n/a	chrII 316,397	contains similarity to Interpro domain IPR002229 (Blood group Rhesus C/E and D polypeptide)
28	ZK666.4	ZK666.4	n/a	chrII 10,477,397	contains similarity to Oryza sativa Putative retinoblastoma-related protein 1.; TR:Q84QM3
29	B0379.2	B0379.2	n/a	chrI 10,071,342	contains similarity to Saccharomyces cerevisiae Possible role for UBP3 in controlling the activity or assembly of the SIR protein complex.; SGD:YER151C
30	C24H12.11	C24H12.11	n/a	chrII 428,376	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
31	C28H8.1	C28H8.1	n/a	chrIII 5,926,486	C28H8.1 is orthologous to the human gene BCL7A (OMIM:601406), which when mutated leads to high-grade B-cell non-Hodgkin lymphoma.
32	gpc-2	F08B6.2	n/a	chrI 6,757,967	gpc-2 encodes one of two C. elegans heterotrimeric G protein gamma subunits; gpc-2 is required, along with its partner GPB-1, a G protein beta subunit, for proper mitotic spindle positioning and orientation during early embryonic cell divisions; to date, GPC-2 expression has been reported in electrically excitable cells (all neurons and muscles).
33	R07C3.7	R07C3.7	n/a	chrII 916,765
34	F44A6.3	F44A6.3	n/a	chrX 10,213,400	contains similarity to Human parainfluenza 1 virus RNA polymerase alpha subunit (EC 2.7.7.48) (Nucleocapsidsphosphoprotein).; SW:RRPP_PI1HB
35	F43G6.5	F43G6.5	n/a	chrII 11,815,623	contains similarity to Pfam domains PF04926 (Poly(A) polymerase predicted RNA binding domain) , PF01909 (Nucleotidyltransferase domain) , PF04928 (Poly(A) polymerase central domain) contains similarity to Interpro domains IPR007012 (Poly(A) polymerase, central region), IPR002934 (Nucleotidyltransferase), IPR007010 (Poly(A) polymerase, RNA-binding region), IPR014492 (Poly(A) polymerase), IPR011068 (Nucleotidyltransferase, class I, C-terminal-like)
36	R166.3	R166.3	n/a	chrII 10,538,486	The R166.3 gene encodes an unfamiliar protein, with homologs in yeast and archaea, that is orthologous to the human gene ALPORT SYNDROME, MENTAL RETARDATION, MIDFACE HYPOPLASIA, AND ELLIPTOCYTOSIS CHROMOSOMAL REGION GENE 1 (AMMECR1; OMIM:300195); AMMECR1, when mutated, may be at least partially responsible for mental retardation, midface hypoplasia, or elliptocytosis.
37	cal-3	M02B7.6	n/a	chrIV 3,832,350	cal-3 encodes a member of the calmodulin family.
38	T02G5.11	T02G5.11	n/a	chrII 7,080,284	contains similarity to Pfam domain PF05741 Nanos RNA binding domain contains similarity to Interpro domain IPR008705 (Zinc finger, Nanos)
39	str-1	C42D4.5	n/a	chrIV 7,174,381	C. elegans STR-1 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
40	F21D5.9	F21D5.9	n/a	chrIV 8,724,343	contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
41	dct-13	Y116A8C.17	n/a	chrIV 17,024,680	Y116A8C.17 encodes a CCCH tandem zinc finger (TZF) protein; based upon its sequence similarity to other TZF proteins, such as MEX-5 and POS-1, the product of Y116A8C.17 is predicted to function as an RNA-binding protein.
42	srt-13	ZC142.1	n/a	chrV 4,249,044	C. elegans SRT-13 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR000539 (Frizzled protein)
43	C17E4.2	C17E4.2	n/a	chrI 9,413,650	contains similarity to Trichomonas vaginalis G3 Viral A-type inclusion protein, putative.; TR:A2EJ43
44	set-10	F33H2.7	n/a	chrI 15,029,120	set-10 encodes a divergent ortholog of human SMYD1 (OMIM:606846), SMYD2 (OMIM:610663), and SYMD3 (OMIM:608783); SET-10 is paralogous to SET-14, SET-18, and SET-30; SET-10 has no obvious function in individual RNAi assays of vulval development, or in mass RNAi assays.
45	fbxb-24	Y56A3A.15	n/a	chrIII 11,909,309	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
46	srab-13	F59A7.3	n/a	chrV 2,026,295	C. elegans SRAB-13 protein ;
47	grl-18	T05C3.4	n/a	chrV 5,487,265	grl-18 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central proline-rich region, and a C-terminal Ground-like (Grl) domain; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
48	ncs-2	F10G8.5	n/a	chrI 10,034,037	C. elegans NCS-2 protein; contains similarity to Pfam domain PF00036 EF hand contains similarity to Interpro domains IPR001125 (Recoverin), IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand), IPR000261 (EPS15 homology (EH))
49	T08G5.7	T08G5.7	n/a	chrV 14,044,675	contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR003656 (Zinc finger, BED-type predicted), IPR007087 (Zinc finger, C2H2-type)
50	F37B4.10	F37B4.10	n/a	chrV 2,876,718	contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)