UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	M03E7.1	M03E7.1	8e-67	chrV 5,624,123	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
2	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
3	C44H9.8	C44H9.8	n/a	chrV 12,847,707	contains similarity to Bacillus anthracis Sensory box histidine kinase PhoR.; TR:Q81L02
4	flp-6	F07D3.2	n/a	chrV 9,472,810	C. elegans FLP-6 protein; contains similarity to Pfam domain PF01581 FMRFamide related peptide family
5	ZK816.1	ZK816.1	n/a	chrX 3,359,733
6	C02B8.7	C02B8.7	n/a	chrX 8,137,743
7	C30B5.7	C30B5.7	n/a	chrII 6,225,999	contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR003944 (Protease-activated receptor 4)
8	tig-2	F39G3.8	n/a	chrV 4,728,435	The tig-2 gene, like dbl-1, daf-7, and unc-129, encodes a TGF-beta-like protein.
9	C01B7.7	C01B7.7	n/a	chrV 8,822,188	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR002542 (Protein of unknown function DUF19)
10	nlp-10	F37A8.4	n/a	chrIII 3,934,743	nlp-10 encodes four predicted neuropeptide-like proteins; nlp-10 is part of a GGxY neuropeptide family that has members in several other nematode species; nlp-10 is expressed in a variety of neurons, including ASK, ADL, CAN, two lateral neurons, two anterior pharyngeal neurons, one tail neuron, and one male tail neuron; as loss of nlp-10 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of nlp-10-encoded peptides in development and/or behavior is not yet known.
11	C24D10.8	C24D10.8	n/a	chrIV 5,165,608	n/a
12	K09H11.6	K09H11.6	n/a	chrV 5,735,411
13	ubc-22	C06E2.7	n/a	chrX 8,868,414	ubc-22 encodes an E2 ubiquitin-conjugating enzyme orthologous to Saccharomyces cerevisiae UBC8 and human UBC1/HIP2 (Huntingtin interacting protein 2, OMIM:602846) which are involved in regulating fructose-1,6-bisphosphatase and huntingtin catabolism, respectively; by homology, UBC-22 is likely required for covalent attachment of ubiquitin to select target proteins to facilitate their degradation; however, as loss of UBC-22 activity via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of UBC-22 in C. elegans development and/or behavior is not yet known.
14	npr-3	C10C6.2	n/a	chrIV 11,461,555	C10C6.2 encodes a G-protein-coupled receptor for the FMRFamide-related peptides (FaRPs) encoded by flp-15; C10C6.2 is primarily coupled to Gi/Go proteins, since C10C6.2 signalling is blocked by pertussis toxin; because of its link to Gi/Go proteins, C10C6.2 is expected to be inhibitory
15	clec-37	Y102A5B.3	n/a	chrV 16,851,225	C. elegans CLEC-37 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
16	egl-20	W08D2.1	n/a	chrIV 9,813,959	egl-20 encodes a member of the WNT family of developmental signaling proteins that affects migration of QL and QR and their descendents; expressed in muscle and epidermal cells at the posterior of the worm.
17	K02F6.8	K02F6.8	n/a	chrII 2,533,862	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
18	K03B4.4	K03B4.4	n/a	chrV 4,684,430	contains similarity to Interpro domain IPR002411 (Cereal allergen/alpha-amylase inhibitor, rice-type)
19	W05E10.2	W05E10.2	n/a	chrV 11,688,773	contains similarity to Homo sapiens Hypothetical protein; ENSEMBL:ENSP00000288462
20	F40G9.8	F40G9.8	n/a	chrIII 164,235
21	aqp-5	C35A5.1	n/a	chrV 10,492,631	aqp-5 encodes a putative aquaporin with no known substrate, since AQP-5 expressed in Xenopus oocytes has no effect on water, glycerol, or urea permeability; AQP-5 also has no function in mass RNAi assays, perhaps reflecting genetic redundancy with its paralogs AQP-4 and AQP-6; AQP-5 is expressed in I1 and I2 pharyngeal interneurons, and is orthologous to human AQP8 (OMIM:603750).
22	twk-9	ZK1251.8	n/a	chrIV 9,695,064	C. elegans TWK-9 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR013099 (Ion transport 2)
23	unc-46	C04F5.3	n/a	chrV 5,098,120	unc-46 encodes a novel protein with a single predicted transmembrane domain; UNC-46 and UNC-47, a novel transmembrane vesicular GABA transporter, are required in GABAergic neurons for all GABA neurotransmission, specifically for loading of GABA into synaptic vesicles, where UNC-46 is localized; UNC-46 localization requires UNC-47, which when overexpressed can rescue unc-46 mutant animals.
24	Y42A5A.1	Y42A5A.1	n/a	chrV 11,093,039	contains similarity to Pfam domain PF01433 Peptidase family M1 contains similarity to Interpro domains IPR014782 (Peptidase M1, membrane alanine aminopeptidase, N-terminal), IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR001930 (Peptidase M1, membrane alanine aminopeptidase)
25	sue-1	F07A5.5	n/a	chrI 7,365,960	C. elegans SUE-1 protein; contains similarity to Pfam domain PF00008 EGF-like domain contains similarity to Interpro domains IPR000742 (EGF-like, type 3), IPR006209 (EGF-like), IPR006210 (EGF), IPR013032 (EGF-like region, conserved site)
26	F54B8.4	F54B8.4	n/a	chrV 15,816,808	The F54B8.4 gene encodes a homolog of Death Associated Protein 1 (DAP-1) protein that may be involved in apoptosis.
27	glc-3	ZC317.3	n/a	chrV 5,451,485	The glc-3 gene encodes a fipronil and BIDN-sensitive, but picrotoxinin-insensitive, L-glutamate-gated chloride channel subunit.
28	srj-15	Y40B10B.2	n/a	chrV 1,963,860	C. elegans SRJ-15 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR002120 (Thyrotrophin-releasing hormone receptor)
29	F23F1.7	F23F1.7	n/a	chrII 39,046	contains similarity to Interpro domains IPR011001 (Saposin-like), IPR008139 (Saposin B)
30	Y37H2C.1	Y37H2C.1	n/a	chrV 18,275,256	contains similarity to Homo sapiens SIDT1 protein; ENSEMBL:ENSP00000377416
31	C17H11.1	C17H11.1	n/a	chrX 8,177,329	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000565 (DNA topoisomerase, type IIA, subunit B), IPR000276 (GPCR, rhodopsin-like)
32	T27F2.4	T27F2.4	n/a	chrV 11,650,405	contains similarity to Interpro domain IPR004827 (Basic-leucine zipper (bZIP) transcription factor)
33	T01G1.2	T01G1.2	n/a	chrIV 11,354,720	contains similarity to Escherichia coli HtrA suppressor protein (Protein prlF).; SW:SOHA_ECOLI
34	glb-15	F35B12.8	n/a	chrV 11,617,517	glb-15 encodes a globin with no obvious function in mass RNAi assays.
35	C55A1.7	C55A1.7	n/a	chrV 15,647,283	contains similarity to Escherichia coli TolA protein.; SW:TOLA_ECOLI
36	F02C12.2	F02C12.2	n/a	chrX 13,398,638	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR002424 (Insect alcohol dehydrogenase family), IPR003560 (2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding), IPR001100 (Pyridine nucleotide-disulphide oxidoreductase, class I)
37	pqn-48	K07D4.8	n/a	chrII 4,040,965	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
38	C13A10.2	C13A10.2	n/a	chrII 1,357,598
39	F10F2.4	F10F2.4	n/a	chrIII 4,624,572	contains similarity to Pfam domain PF00560 Leucine Rich Repeat contains similarity to Interpro domains IPR000483 (Cysteine-rich flanking region, C-terminal), IPR001611 (Leucine-rich repeat), IPR003591 (Leucine-rich repeat, typical subtype)
40	C44H9.5	C44H9.5	n/a	chrV 12,849,210	contains similarity to Trypanosoma brucei Hypothetical leucine-rich repeat protein 1 (LRRP1).; TR:Q8WPS9
41	F18A11.5	F18A11.5	n/a	chrII 13,010,794	contains similarity to Pfam domains PF02214 (K+ channel tetramerisation domain) , PF03931 (Skp1 family, tetramerisation domain) contains similarity to Interpro domains IPR001232 (SKP1 component), IPR016072 (SKP1 component, dimerisation), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation), IPR016073 (SKP1 component, POZ)
42	gpa-10	C55H1.2	n/a	chrV 6,853,746	gpa-10 encodes a member of the G protein alpha subunit family of heterotrimeric GTPases; it is expressed in ADF, ASI, ASJ, ALN, CAN, LUA, and the spermatheca.
43	B0563.7	B0563.7	n/a	chrX 9,153,274	contains similarity to Pfam domain PF00036 EF hand contains similarity to Interpro domains IPR001125 (Recoverin), IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand), IPR003299 (Flagellar calcium-binding protein (calflagin)), IPR000261 (EPS15 homology (EH))
44	T01C8.4	T01C8.4	n/a	chrX 16,788,345	contains similarity to Pfam domain PF00155 Aminotransferase class I and II contains similarity to Interpro domains IPR004838 (Aminotransferases, class-I, pyridoxal-phosphate-binding site), IPR015422 (Pyridoxal phosphate-dependent transferase, major region, subdomain 2), IPR015424 (Pyridoxal phosphate-dependent transferase, major region), IPR004839 (Aminotransferase, class I and II), IPR000796 (Aspartate/other aminotransferase), IPR015421 (Pyridoxal phosphate-dependent transferase, major region, subdomain 1)
45	C38C3.6	C38C3.6	n/a	chrV 1,485,347	contains similarity to Interpro domain IPR000694 (Proline-rich region)
46	cal-1	C13C12.1	n/a	chrV 12,515,481	cal-1 encodes one of five predicted C. elegans calcium-binding calmodulin homologs (the others being CAL-2, CAL-3, CAL-4, and CMD-1); as loss of cal-1 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of CAL-1 in C. elegans development and/or behavior is not yet known.
47	clec-113	F47G4.1	n/a	chrI 14,055,730	C. elegans CLEC-113 protein; contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domains IPR006583 (CW), IPR016187 (C-type lectin fold), IPR001304 (C-type lectin)
48	C02B8.3	C02B8.3	n/a	chrX 8,139,820
49	gly-18	F22D6.11	n/a	chrI 7,111,262	GLY-18 is similar to 2/I N-acetylglucosaminyltransferase.
50	srx-85	F38B7.4	n/a	chrV 11,553,428	C. elegans SRX-85 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)