UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	atg-2	M03A8.2	0	chrX 6,813,114	atg-2 encodes a large (2,275-residue) protein orthologous to the autophagic budding yeast protein Atg2p, and to human ATG2A and ATG2B; ATG-2 is expressed in larval and adult pharynx, intestine, body wall muscles, and neurons, as well as adult reproductive system; ATG-2 has no obvious phenotype in mass RNAi assays.
2	nhr-59	T27B7.1	n/a	chrV 2,277,137	C. elegans NHR-59 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
3	nhr-10	B0280.8	n/a	chrIII 7,113,797	nhr-10 encodes a predicted nuclear hormone receptor diverged from nuclear hormone receptors in other phyla; its mRNA is expressed throughout development with possibly lower expression from the L4 larval to adult stages, and the protein is expressed in neuronal processes.
4	abt-6	F56F4.6	n/a	chrI 6,139,832	F56F4.6 encodes a protein that contains an ATP-binding cassette (ABC) that is most closely related to that of the ABCA subfamily of ABC transport proteins; as the product of F56F4.6 lacks a predicted transmembrane domain, and as loss of F56F4.6 activity via RNAi results in no obvious defects, the precise role of this gene in C. elegans development and/or behavior is not yet known.
5	K02A11.2	K02A11.2	n/a	chrI 9,745,095	contains similarity to Saccharomyces cerevisiae Nucleolar protein that binds nuclear localization sequences, required for pre-rRNA processing and ribosome biogenesis; SGD:YGR159C
6	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
7	srsx-37	M01B2.7	n/a	chrV 15,258,341	C. elegans SRSX-37 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
8	clec-147	C04H5.2	n/a	chrII 14,536,651	C. elegans CLEC-147 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
9	K05F1.5	K05F1.5	n/a	chrII 5,791,755	contains similarity to Pfam domain PF01551 Peptidase family M23 contains similarity to Interpro domains IPR016047 (Peptidase M23), IPR008663 (Leukocyte cell-derived chemotaxin 2), IPR011055 (Duplicated hybrid motif)
10	F59C6.3	F59C6.3	n/a	chrI 10,524,961	contains similarity to Rhizobium meliloti Hypothetical membrane protein SMb20625.; TR:Q92TI1
11	C41G7.7	C41G7.7	n/a	chrI 9,534,916	contains similarity to Plasmodium falciparum S-antigen (Fragment).; TR:Q9GZB4
12	unc-79	E03A3.6	n/a	chrIII 4,074,729	unc-79 encodes a novel, conserved protein; unc-79 functions in a pathway with nca-1 and nca-2, which encode ion channel subunits, to regulate locomotion and the response to specific volatile anesthetics; unc-79 exerts its effects on these processes, at least in part, by regulating the levels of NCA-1 and NCA-2 proteins; an unc-79::gfp reporter is expressed in the nervous system in ventral nerve cord neurons in L2 and L3 larvae and in one or two head neurons in adults.
13	srbc-67	T24A6.10	n/a	chrV 3,539,627	C. elegans SRBC-67 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
14	ugt-2	AC3.8	n/a	chrV 10,399,988	C. elegans UGT-2 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
15	F18A12.5	F18A12.5	n/a	chrII 3,397,557	F18A12.5 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; F18A12.5 has no clear orthologs in other organisms.
16	D2063.2	D2063.2	n/a	chrV 4,330,780	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
17	Y116A8C.19	Y116A8C.19	n/a	chrIV 17,039,245	Y116A8C.19 encodes a CCCH tandem zinc finger (TZF) protein; based upon its sequence similarity to C. elegans POS-1, the product of Y116A8C.19 is predicted to function as an RNA-binding protein.
18	F14D2.9	F14D2.9	n/a	chrII 3,354,397	contains similarity to Xenopus laevis Putative uncharacterized protein.; TR:Q08AY0
19	C01G5.3	C01G5.3	n/a	chrIV 6,537,601	contains similarity to Homo sapiens hypothetical protein; ENSEMBL:ENSP00000352916
20	F44D12.3	F44D12.3	n/a	chrIV 10,022,456	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
21	srh-78	DC2.2	n/a	chrV 218,314	C. elegans SRH-78 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
22	F12A10.4	F12A10.4	n/a	chrII 5,489,365	F12A10.4 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; F12A10.4 has no clear orthologs in other organisms.
23	fbxa-224	ZK1290.9	n/a	chrII 7,547,404	fbxa-224 encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
24	ttr-6	T28B4.3	n/a	chrX 6,596,773	C. elegans TTR-6 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
25	srx-6	F07G11.8	n/a	chrV 7,312,511	C. elegans SRX-6 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
26	T11A5.1	T11A5.1	n/a	chrV 9,859,109	contains similarity to Pfam domain PF02178 AT hook motif contains similarity to Interpro domains IPR000637 (HMG-I and HMG-Y, DNA-binding), IPR008162 (Inorganic pyrophosphatase)
27	T04F8.4	T04F8.4	n/a	chrX 11,649,562	contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domain IPR001507 (Endoglin/CD105 antigen)
28	wht-3	C16C10.12	n/a	chrIII 4,149,469	C16C10.12 encodes an ATP-binding cassette (ABC) transporter; C16C10.12 activity is required for efficient RNA interference (RNAi) of a germline-expressed target, pop-1.
29	C16C8.18	C16C8.18	n/a	chrII 3,430,314	contains similarity to Bos taurus Protein FAM82A.; SW:Q2TBQ7
30	kin-34	R02C2.2	n/a	chrV 245,158	C. elegans KIN-34 protein; contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
31	Y43F8C.9	Y43F8C.9	n/a	chrV 19,646,679	contains similarity to Dictyostelium discoideum Myb-like protein.; SW:P34127
32	clec-141	EEED8.11	n/a	chrII 5,406,695	C. elegans CLEC-141 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR001304 (C-type lectin)
33	C09D4.6	C09D4.6	n/a	chrI 5,486,821
34	tbx-11	F40H6.4	n/a	chrIII 6,046,285	tbx-11 encodes a T-box transcription factor that is orthologous to members of the Tbx2 subfamily of T-box transcription factors; by homology, TBX-11 is predicted to function in transcriptional regulation during cellular differentiation, potentially as both an activator and a repressor; however, as loss of tbx-11 function via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of tbx-11 in C. elegans development and/or behavior is not yet known.
35	tag-19	C09G9.4	n/a	chrIV 8,875,605	tag-19 superficially resembles aromatic-L-amino-acid/L-histidine decarboxylases; however, it is distantly related, being no closer to them than to glutamine decarboxylase/sphingosinge lyase (e.g., tag-38, spl-1); tag-19 thus might be termed a Pyridoxal-phosphate (PLP) dependent decarboxylase-like protei, but is missing the absolutely conserved Lys residue of all PLP-DCs (hence the -like would be needed); tag-19 is dispensable in mass RNAi assays.
36	srg-21	Y25C1A.9	n/a	chrII 3,089,880	C. elegans SRG-21 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
37	F55C12.2	F55C12.2	n/a	chrII 5,877,311
38	ceh-33	C10G8.7	n/a	chrV 5,323,911	ceh-33 encodes a Six/sine oculis class homeodomain transcription factor; preliminary RNAi experiments suggest that CEH-33 activity may be required for gonad development; a ceh-33::gfp reporter shows very weak pharyngeal expression in late embryos and early larvae.
39	Y68A4B.3	Y68A4B.3	n/a	chrV 17,241,853	contains similarity to Ehrlichia canis 28 kDa outer membrane protein (Fragment).; TR:Q9R3J3
40	T15B7.6	T15B7.6	n/a	chrV 6,826,715
41	dsl-5	F58B3.8	n/a	chrIV 11,620,190	dsl-5 encodes a putative secreted protein with single DSL and EGF domains in series, somewhat like Delta/LAG-2; DSL-5 belongs to a nematode-specific family of Delta/LAG-2-like proteins that includes DSL-1, -2, -3, -5, -6, and -7.
42	lgc-11	F48E3.7	n/a	chrX 7,505,176	acr-22 encodes a predicted member of the nicotinic acetylcholine receptor nonalpha subunit family with highest similarity to human neuronal acetylcholine receptor alpha-9 subunit.
43	Y43F8B.10	Y43F8B.10	n/a	chrV 19,475,668
44	srj-20	Y45G12C.15	n/a	chrV 2,572,367	C. elegans SRJ-20 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
45	F26F4.8	F26F4.8	n/a	chrIII 4,904,678	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
46	F09C12.2	F09C12.2	n/a	chrII 5,111,113	F09C12.2 encodes a kinase most closely related to mitogen-activated protein (MAP) kinases; as loss of F09C12.2 activity via mutation or large-scale RNAi results in no obvious defects, the precise role of F09C12.2 in C. elegans development and/or behavior is not yet known.
47	Y70C5B.1	Y70C5B.1	n/a	chrV 16,662,837
48	D2005.6	D2005.6	n/a	chrI 7,790,102	contains similarity to Homo sapiens Fusion protein SYT-SSX1; ENSEMBL:ENSP00000269138
49	tbx-41	T26C11.1	n/a	chrX 1,865,937	C. elegans TBX-41 protein; contains similarity to Pfam domain PF00907 T-box contains similarity to Interpro domains IPR008967 (p53-like transcription factor, DNA-binding), IPR001699 (Transcription factor, T-box)
50	T05A8.5	T05A8.5	n/a	chrII 2,733,284	contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)