UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	clec-265	M02F4.7	0	chrX 3,032,455	C. elegans CLEC-265 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin), IPR002353 (Type II antifreeze protein)
2	kin-4	C10C6.1	n/a	chrIV 11,441,819	C. elegans KIN-4 protein; contains similarity to Pfam domains PF08926 (Domain of unknown function (DUF1908)) , PF00595 (PDZ domain (Also known as DHR or GLGF)) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR015022 (Region of unknown function DUF1908), IPR000719 (Protein kinase, core), IPR001478 (PDZ/DHR/GLGF), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR000961 (Protein kinase, C-terminal)
3	ilys-2	C45G7.2	n/a	chrIV 2,468,243	C. elegans ILYS-2 protein; contains similarity to Pfam domain PF05497 Destabilase contains similarity to Interpro domain IPR008597 (Destabilase)
4	W07G4.1	W07G4.1	n/a	chrV 13,033,814	contains similarity to Interpro domain IPR009050 ()
5	C09G5.2	C09G5.2	n/a	chrII 10,708,359	C09G5.2 encodes an ortholog of S. cerevisiae DPH2/YKL191W and human DPH2L2 (OMIM:603456); C09G5.2 is a putative protein component of diphtamide synthesis; C09G5.2 has no obvious function in mass RNAi assays.
6	W03H9.2	W03H9.2	n/a	chrII 14,144,403	contains similarity to Homo sapiens Conserved hypothetical protein; HI:HIT000046554
7	C50F4.12	C50F4.12	n/a	chrV 9,538,883	contains similarity to Interpro domain IPR003690 (Mitochodrial transcription termination factor-related)
8	secs-1	D1054.13	n/a	chrV 10,803,314	C. elegans SECS-1 protein; contains similarity to Pfam domain PF05889 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) contains similarity to Interpro domains IPR015424 (Pyridoxal phosphate-dependent transferase, major region), IPR008829 (Soluble liver antigen/liver pancreas antigen)
9	C46H11.2	C46H11.2	n/a	chrI 5,051,289	contains similarity to Pfam domains PF00743 (Flavin-binding monooxygenase-like) , PF00070 (Pyridine nucleotide-disulphide oxidoreductase) contains similarity to Interpro domains IPR013027 (FAD-dependent pyridine nucleotide-disulphide oxidoreductase), IPR000759 (Adrenodoxin reductase), IPR000960 (Flavin-containing monooxygenase FMO), IPR000103 (Pyridine nucleotide-disulphide oxidoreductase, class-II), IPR001327 (Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region), IPR016040 (NAD(P)-binding), IPR001100 (Pyridine nucleotide-disulphide oxidoreductase, class I)
10	R105.1	R105.1	n/a	chrIV 4,635,811	contains similarity to Pfam domain PF03762 Vitelline membrane outer layer protein I (VOMI) contains similarity to Interpro domain IPR005515 (Vitelline membrane outer layer protein I (VOMI))
11	str-40	C50H11.12	n/a	chrV 3,068,667	C. elegans STR-40 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
12	F52B11.2	F52B11.2	n/a	chrIV 14,084,140	F52B11.2 is orthologous to the human gene PHOSPHOMANNOMUTASE 2 (PMS2; OMIM:601785), which when mutated leads to congenital disorder of glycosylation, type Ia.
13	ulp-4	C41C4.6	n/a	chrII 8,132,271	C. elegans ULP-4 protein; contains similarity to Pfam domain PF02902 Ulp1 protease family, C-terminal catalytic domain contains similarity to Interpro domain IPR003653 (Peptidase C48, SUMO/Sentrin/Ubl1)
14	ekl-1	F22D6.6	n/a	chrI 7,096,946	C. elegans EKL-1 protein; contains similarity to Pfam domain PF00567 Tudor domain contains similarity to Interpro domains IPR008191 (Maternal tudor protein), IPR002999 (Tudor)
15	C10A4.7	C10A4.7	n/a	chrX 7,414,514
16	C27B7.2	C27B7.2	n/a	chrIV 8,893,280	contains similarity to Arabidopsis thaliana F3O9.12 protein (At1g16320/F3O9_12).; TR:Q9SA31
17	fbxa-200	T07D3.1	n/a	chrII 905,248	C. elegans FBXA-200 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
18	nhr-257	C17A2.1	n/a	chrII 3,853,795	C. elegans NHR-257 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
19	end-1	F58E10.2	n/a	chrV 13,986,046	end-1 encodes a GATA-like transcription factor sufficient to initiate endoderm differentiation and binds to the canonical target DNA sequence WGATAR with specificity similar to GATA-1 and D4 transcription factors; its expression bypasses requirement for maternal SKN-1 and the maternal Wnt signaling pathway in endoderm formation and it activates endoderm differentiation in isolated Xenopus ectoderm.
20	F41G4.7	F41G4.7	n/a	chrX 16,834,908
21	drh-3	D2005.5	n/a	chrI 7,823,605	drh-3 encodes a DExH-box helicase.
22	sru-29	C50C10.2	n/a	chrV 9,812,012	C. elegans SRU-29 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
23	srw-8	F59D6.5	n/a	chrV 3,033,490	C. elegans SRW-8 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
24	W03A5.6	W03A5.6	n/a	chrIII 5,440,330
25	dnj-17	T03F6.2	n/a	chrIII 13,392,282	This gene encodes a protein containing a DnaJ ('J') domain.
26	Y48A5A.1	Y48A5A.1	n/a	chrIV 1,967,552	contains similarity to Pfam domain PF04925 SHQ1 protein contains similarity to Interpro domain IPR007009 (SHQ1 protein)
27	pdhk-2	ZK370.5	n/a	chrIII 8,739,634	C. elegans PDHK-2 protein; contains similarity to Pfam domain PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase contains similarity to Interpro domains IPR005467 (Signal transduction histidine kinase, core), IPR004358 (Signal transduction histidine kinase-related protein, C-terminal), IPR003594 (ATP-binding region, ATPase-like)
28	F13H8.3	F13H8.3	n/a	chrII 6,264,731	contains similarity to Pfam domain PF01156 Inosine-uridine preferring nucleoside hydrolase contains similarity to Interpro domain IPR001910 (Inosine/uridine-preferring nucleoside hydrolase)
29	his-31	F17E9.12	n/a	chrIV 8,333,809	his-31 encodes an H4 histone; his-31 is contained within the histone gene cluster HIS5.
30	Y17G7B.3	Y17G7B.3	n/a	chrII 11,990,838	Y17G7B.3 is orthologous to the human gene HYDROXYACYLGLUTATHIONE HYDROLASE (HAGH; OMIM:138760), which when mutated leads to disease.
31	F45F2.5	F45F2.5	n/a	chrV 8,531,457	contains similarity to Pfam domain PF03189 Protein of unknown function, DUF270 contains similarity to Interpro domain IPR004878 (Protein of unknown function DUF270)
32	C18G1.6	C18G1.6	n/a	chrV 4,752,187	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
33	K03B4.1	K03B4.1	n/a	chrV 4,690,455
34	C52B11.5	C52B11.5	n/a	chrX 1,274,112	contains similarity to Pfam domains PF00071 (Ras family) , PF08477 (Miro-like protein) contains similarity to Interpro domains IPR003577 (Ras small GTPase, Ras type), IPR013684 (Miro-like), IPR003578 (Ras small GTPase, Rho type), IPR005225 (Small GTP-binding protein), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR013753 (Ras)
35	C05A9.3	C05A9.3	n/a	chrX 10,830,625	contains similarity to Pfam domain PF00023 Ankyrin repeat contains similarity to Interpro domain IPR002110 (Ankyrin)
36	C53D6.7	C53D6.7	n/a	chrIV 9,035,988	contains similarity to Pfam domain PF00337 Galactoside-binding lectin contains similarity to Interpro domains IPR001079 (Galectin, galactose-binding lectin), IPR013320 (Concanavalin A-like lectin/glucanase, subgroup), IPR008985 (Concanavalin A-like lectin/glucanase)
37	glc-2	F25F8.2	n/a	chrI 4,886,565	glc-2 encodes the beta subunit of a glutamate-gated chloride channel; in vivo, GLC-2 is capable of forming homomeric glutamate-activated channels, as well as heteromeric channels with GLC-1 that can be activated by glutamate and avermectins, antihelmintics that inhibit pharyngeal pumping; as loss of glc-2 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of GLC-2 in development and/or behavior is not yet known; however, GLC-2 expression is generally restricted to the pm4 pharyngeal muscles of larvae and adults, suggesting a role for GLC-2 in regulation of glutamatergic inhibition of pharyngeal pumping.
38	K11E4.2	K11E4.2	n/a	chrX 13,718,299	contains similarity to Pfam domain PF00017 SH2 domain contains similarity to Interpro domains IPR006020 (Phosphotyrosine interaction region), IPR000980 (SH2 motif)
39	glb-18	F52A8.4	n/a	chrI 7,344,423	glb-18 encodes a globin; glb-18 is expressed in larval and adult neurons and excretory gland cells, and in adult spermetheca and vulva; glb-18 transcription is higher in L3 and dauers than in young adults; glb-18 has no obvious function in mass RNAi assays.
40	ZK596.3	ZK596.3	n/a	chrIV 10,903,190	contains similarity to Mus musculus DNA-dependent protein kinase catalytic subunit (EC 2.7.1.37) (DNA-sPKcs) (P460).; SW:PRKD_MOUSE
41	srx-53	T27C5.2	n/a	chrV 17,400,916	C. elegans SRX-53 protein; contains similarity to Interpro domain IPR010989 (t-SNARE)
42	C07H6.4	C07H6.4	n/a	chrIII 7,501,398	contains similarity to Pfam domains PF01805 (Surp module) , PF00076 (RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)) contains similarity to Interpro domains IPR006569 (Regulation of nuclear pre-mRNA protein), IPR000061 (SWAP/Surp), IPR012677 (Nucleotide-binding, alpha-beta plait), IPR008942 (ENTH/VHS), IPR000504 (RNA recognition motif, RNP-1)
43	sru-8	R07B5.7	n/a	chrV 9,844,985	C. elegans SRU-8 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domains IPR001463 (Sodium:alanine symporter), IPR003839 (Protein of unknown function DUF215)
44	C06A5.4	C06A5.4	n/a	chrI 5,981,191	contains similarity to Interpro domain IPR006578 (MADF)
45	K10D11.2	K10D11.2	n/a	chrIV 12,980,447	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domain IPR003366 (CUB-like region)
46	F09G8.5	F09G8.5	n/a	chrIII 8,256,200	contains similarity to Pfam domain PF00560 Leucine Rich Repeat contains similarity to Interpro domains IPR003603 (U2A'/phosphoprotein 32 family A, C-terminal), IPR010916 (TonB box, conserved site)
47	srw-118	C44C3.5	n/a	chrV 2,979,418	C. elegans SRW-118 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
48	C08F11.1	C08F11.1	n/a	chrIV 13,624,656	contains similarity to Coxiella burnetii Hypothetical protein.; TR:Q83D43
49	K02D10.4	K02D10.4	n/a	chrIII 8,778,867
50	lig-4	C07H6.1	n/a	chrIII 7,523,062	lig-4 encodes an ortholog of DNA ligase IV in budding yeast (DNL4) and human (LIG4; OMIM:601837, mutated in LIG4 syndrome); LIG-4 is required for resistance to ionizing radiation (IR) in somatic tissues (such as motor neurons, vulva, or uterus) and in endoreduplicating intestinal cells, but not in the germline (e.g., in dog-1-induced lesions); LIG-4 is required for non-homologous end-joining of double-stranded breaks (DSB) in somatic genomic DNA; although LIG-4 is not strongly required in the germline, it is active on DSB of DNA injected into syncytial gonads, and its absence enhances the hypersensitivity of rad-51(RNAi) germlines to ionizing radiation; in meiotic cells deprived of homologous DNA repair by a rad-51(Ig08701) mutation, both LIG-4 and BRC-2 can promote chromosomal aggregation (presumably by repairing meiotic double-stranded breaks in DNA), but they do so independently; mutant lig-4 late-stage embryos or dauer larvae are hypersensitive to radiation-induced DNA damage in somatic cells; after irradiation, lig-4 mutants tend to display various postembryonic phenotypes (such as slow growth, uncoordinated locomotion, impaired egg-laying, or vulval defects) that are thought to reflect missegregation of fragmented chromosomes; LIG-4 is N-terminally acetylated on a serine residue.