UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	M01F1.7	M01F1.7	0	chrIII 3,525,420	M01F1.7 encodes a phosphatidylinositol transfer protein, with a C-terminal DDHD domain, that is orthologous to RETINAL DEGENERATION B (RDGB) in D. melanogaster, as well as other orthologs in mammals (NIR1-3); M01F1.7 is expressed in the egg membrane, the germline, the spermatheca and three pairs of head neurons; while M01F1.7 would be expected to mediate PIP(2) signalling in either neuronal function or cytokinesis, it has not yet had a published mutant phenotype, and has no obvious function in mass RNAi assays.
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	M60.6	M60.6	n/a	chrX 8,250,273
4	srz-18	F46B3.11	n/a	chrV 20,622,846	C. elegans SRZ-18 protein; contains similarity to Interpro domain IPR001036 (Acriflavin resistance protein)
5	T03G11.3	T03G11.3	n/a	chrX 5,175,968	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domain IPR007087 (Zinc finger, C2H2-type)
6	F42G8.5	F42G8.5	n/a	chrIV 8,137,753
7	W01C9.2	W01C9.2	n/a	chrII 8,537,366	contains similarity to Chlamydia pneumoniae Probable serine/threonine-protein kinase 1 (EC 2.7.1.37).; SW:PKN1_CHLPN
8	osm-10	T20H4.1	n/a	chrIII 7,244,451	osm-10 encodes a novel protein conserved amongst several Caenorhabditis species; osm-10 activity is required for normal osmosensory signaling in the ASH sensory neuron; in regulating ASH-mediated osmosensation, osm-10 interacts genetically with eos-1 and eos-2; OSM-10 is expressed in the ASH, ASI, PHA, and PHB sensory neurons beginning just prior to hatching and continuing through larval and adult stages; OSM-10 localizes to cell bodies, sensory processes, and axons.
9	F42A9.9	F42A9.9	n/a	chrIV 8,638,434
10	ZC317.2	ZC317.2	n/a	chrV 5,460,748
11	fbxa-3	T08E11.7	n/a	chrII 1,819,483	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
12	fbxa-135	T06E6.5	n/a	chrV 15,402,649	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
13	F23D12.1	F23D12.1	n/a	chrX 14,425,936	contains similarity to Clostridium perfringens Hypothetical protein CPE1252.; TR:Q8XKZ0
14	K09E3.1	K09E3.1	n/a	chrX 17,126,661
15	B0212.1	B0212.1	n/a	chrIV 3,575,057	contains similarity to Pfam domain PF03189 Protein of unknown function, DUF270 contains similarity to Interpro domain IPR004878 (Protein of unknown function DUF270)
16	fbxa-10	T12B5.3	n/a	chrIII 953,160	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
17	F22D6.8	F22D6.8	n/a	chrI 7,099,204
18	nhr-220	T19H12.8	n/a	chrV 4,883,423	C. elegans NHR-220 protein; contains similarity to Pfam domain PF00105 Zinc finger, C4 type (two domains) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
19	T11F9.14	T11F9.14	n/a	chrV 11,480,742	contains similarity to Oryctolagus cuniculus Troponin I, fast skeletal muscle (Troponin I, fast-twitch isoform).; SW:TRIF_RABIT
20	Y45F10B.12	Y45F10B.12	n/a	chrIV 13,587,824	contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
21	unc-122	F11C3.2	n/a	chrI 14,873,757	unc-122 encodes a predicted type II transmembrane protein with extracellular collagen-like domains and a highly conserved olfactomedin (OLF) domain that is found in a family of secreted proteins involved in formation and function of nervous systems; UNC-122 is required for proper locomotion and for normal morphology of the DVB motorneuron, and may regulate neuromuscular function by acting in an aminergic/peptidergic pathway parallel to cholinergic neurotransmission; although mosaic analysis indicates that UNC-122 activity is required in muscle cells, the precise expression and localization patterns of UNC-122 are not yet known.
22	C35A11.1	C35A11.1	n/a	chrV 5,406,834	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
23	pqn-25	D1044.3	n/a	chrIII 5,510,853	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
24	K01A12.3	K01A12.3	n/a	chrX 8,622,819	contains similarity to Interpro domain IPR000276 (GPCR, rhodopsin-like)
25	F16H11.2	F16H11.2	n/a	chrX 4,662,854	contains similarity to Tetrahymena thermophila SB210 Putative uncharacterized protein.; TR:Q23LR2
26	gpa-3	E02C12.5	n/a	chrV 9,358,223	gpa-3 encodes a member of the G protein alpha subunit family of heterotrimeric GTPases that affects dauer formation, water-soluble chemoattraction and chemoaversion, and volatile chemoattraction; it is expressed in amphid and phasmid neurons and some interneurons.
27	F52D10.6	F52D10.6	n/a	chrX 11,583,279	contains similarity to Pfam domain PF00169 PH domain contains similarity to Interpro domains IPR000219 (Dbl homology (DH) domain), IPR001849 (Pleckstrin-like), IPR011993 (Pleckstrin homology-type)
28	ugt-56	T04H1.8	n/a	chrV 12,260,070	C. elegans UGT-56 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
29	srt-14	ZC142.2	n/a	chrV 4,255,024	C. elegans SRT-14 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
30	pgp-10	C54D1.1	n/a	chrX 7,162,476	pgp-10 encodes an ATP-binding protein that is a member of the P-glycoprotein subclass of the ATP-binding cassette (ABC) transporter superfamily; PGP-10 is predicted to function as a transmembrane protein that couples energy to transport of various molecules across membranes, but as loss of pgp-10 activity via RNAi results in no obvious defects, the exact role of pgp-10 in C. elegans development and/or behavior is not yet known; pgp-10 promoter-gfp fusion proteins are expressed in larvae and adults in the intestine and hypodermis.
31	F58A6.2	F58A6.2	n/a	chrII 5,137,627
32	K08F9.3	K08F9.3	n/a	chrV 15,143,291	contains similarity to Pfam domains PF00168 (C2 domain) (3), PF08165 (FerA (NUC095) domain) , PF08150 (FerB (NUC096) domain) contains similarity to Interpro domains IPR012561 (FerB), IPR006614 (Dysferlin, C-terminal), IPR008973 (C2 calcium/lipid-binding region, CaLB), IPR012560 (FerA), IPR006613 (Dysferlin, N-terminal), IPR000008 (C2 calcium-dependent membrane targeting)
33	glb-2	C06E4.7	n/a	chrIV 7,262,720	glb-2 encodes a globin; glb-2 transcription is higher in L3 and dauers than in young adults; glb-2 has no obvious function in mass RNAi assays.
34	ifta-1	C54G7.4	n/a	chrX 5,549,123	C. elegans IFTA-1 protein; contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR017233 (WD repeat protein 35), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like), IPR011011 (Zinc finger, FYVE/PHD-type)
35	M163.5	M163.5	n/a	chrX 14,475,017	contains similarity to Interpro domain IPR008995 ()
36	dhs-16	C10F3.2	n/a	chrV 5,984,592	dhs-16 encodes a short-chain dehydrogenase predicted to be mitochondrial.
37	C50H2.5	C50H2.5	n/a	chrV 9,919,252	contains similarity to Interpro domains IPR001356 (Homeobox), IPR009057 (Homeodomain-like)
38	ser-5	F16D3.7	n/a	chrI 8,385,819	F16D3.7 encodes a homolog of mammalian alpha-adrenergic receptors that is expressed in vulval and bodywall muscle cells, intestine, and head neurons; heterologously expressed F16D3.7 has no effect on adenylate cyclase signalling; F16D3.7 has no obvious function in RNAi assays of brood size, egg laying, pharyngeal pumping, locomotion, or male mating.
39	kqt-3	Y54G9A.3	n/a	chrII 13,704,530	kqt-3 encodes one of three C. elegans KCNQ-like potassium channel subunits and, with respect to humans, is most similar to the KCNQ1 channel protein which when mutated leads to inherited long QT syndrome (OMIM:607542); although loss of KQT-3 activity via large-scale RNAi screens results in no obvious abnormalities, KQT-3 likely functions to regulate cellular excitability as expression of KQT-3 in Xenopus oocytes can produce K+ channel currents that functionally resemble vertebrate M-currents; activity of these KQT-3 channels can be suppressed by coexpression with the human M1 muscarinic receptor and treatment with diacylglycerol analogs, although KQT-3 is less sensitive to each of these treatments than KQT-1; a KQT-3::GFP fusion protein is expressed in the anterior- and posterior-most intestinal cells, the anterior and posterior mechanosensory neurons ALM and PLM, amphid and phasmid neurons, and in some additional head neurons.
40	nhr-182	F41B5.9	n/a	chrV 2,258,611	C. elegans NHR-182 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
41	sru-40	R07B5.3	n/a	chrV 9,833,347	C. elegans SRU-40 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
42	srj-33	T07C12.1	n/a	chrV 9,936,513	C. elegans SRJ-33 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
43	bbs-2	F20D12.3	n/a	chrIV 7,935,876	bbs-2 is orthologous to human BBS2 (OMIM:606151, mutated in Bardet-Biedl syndrome 2); while the function of BBS-2 is unknown, it shares conserved domains with its human paralogs BBS1 and BBS7, which also are mutated in other Bardet-Biedl syndromes.
44	K08C9.5	K08C9.5	n/a	chrI 11,483,971	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
45	snb-1	T10H9.4	n/a	chrV 6,656,014	The snb-1 gene encodes synaptobrevin, a synaptic vesicle protein orthologous to human vesicle-associated membrane protein 1 (VAMP1 OMIM:185880) and 2 (VAMP2 OMIM:185881), and is required for viability and synaptic transmission; SNB-1 is likely to play a role in vesicle docking and/or fusion and is expressed in neurons where it colocalizes with synaptic vesicle proteins RAB-3 and synaptotagmin.
46	ZK757.2	ZK757.2	n/a	chrIII 9,875,718	contains similarity to Pfam domain PF00782 Dual specificity phosphatase, catalytic domain contains similarity to Interpro domains IPR000387 (Protein-tyrosine phosphatase), IPR000340 (Protein-tyrosine phosphatase, dual specificity)
47	C49A9.7	C49A9.7	n/a	chrIV 6,203,875	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR001681 (Neurokinin receptor), IPR005395 (Neuropeptide FF receptor), IPR005384 (Duffy antigen/chemokine receptor), IPR000611 (Neuropeptide Y receptor), IPR000276 (GPCR, rhodopsin-like)
48	clec-34	T25E12.8	n/a	chrV 16,736,555	C. elegans CLEC-34 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
49	srw-4	F37B4.8	n/a	chrV 2,887,985	C. elegans SRW-4 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
50	R05H10.5	R05H10.5	n/a	chrII 14,868,296	contains similarity to Pfam domain PF00255 Glutathione peroxidase contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR000889 (Glutathione peroxidase)