UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	arx-7	M01B12.3	1.0000000000000001e-82	chrI 3,069,767	arx-7 encodes the C. elegans ortholog of the p16Arc subunit of the actin-related protein (Arp)2/3 complex.
2	K08F4.1	K08F4.1	n/a	chrIV 10,124,631	contains similarity to Pfam domain PF00004 ATPase family associated with various cellular activities (AAA) contains similarity to Interpro domains IPR003959 (AAA ATPase, core), IPR001199 (Cytochrome b5), IPR003593 (AAA+ ATPase, core)
3	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
4	apm-3	F53H8.1	n/a	chrX 956,347	apm-3 encodes an adaptin, orthologous to the mu3 subunit of adaptor protein complex 3 (AP-3); APM-3 is also orthologous to human HPS, which when mutated leads to Hermansky-Pudlak syndrome (OMIM:203300); based on structural similarity, APM-3 is predicted to be involved in the formation of intracellular transport vesicles, and genetic analyses indicate that apm-3 activity is required for biogenesis of lysosome-related gut granules.
5	tag-135	D1054.15	n/a	chrV 10,807,021	C. elegans TAG-135 protein; contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR009146 (Groucho/transducin-like enhancer), IPR001680 (WD40 repeat), IPR011042 (Six-bladed beta-propeller, TolB-like), IPR015943 (WD40/YVTN repeat-like)
6	snr-2	W08E3.1	n/a	chrI 13,339,794	C. elegans SNR-2 protein; contains similarity to Pfam domain PF01423 LSM domain contains similarity to Interpro domains IPR001163 (Like-Sm ribonucleoprotein, core), IPR006649 (Like-Sm ribonucleoprotein, eukaryotic and archaea-type, core), IPR010920 (Like-Sm ribonucleoprotein-related, core)
7	T07F8.4	T07F8.4	n/a	chrII 7,131,218	contains similarity to Pfam domain PF01448 ELM2 domain contains similarity to Interpro domains IPR001005 (SANT, DNA-binding), IPR000949 (ELM2)
8	C05C8.2	C05C8.2	n/a	chrV 7,231,951	contains similarity to Interpro domain IPR004087 (K Homology)
9	F44E7.9	F44E7.9	n/a	chrV 5,791,637	contains similarity to Pfam domain PF07019 Rab5-interacting protein (Rab5ip) contains similarity to Interpro domain IPR010742 (Rab5-interacting)
10	C25A11.2	C25A11.2	n/a	chrX 9,115,559	contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
11	K07C5.3	K07C5.3	n/a	chrV 10,344,230	contains similarity to Pfam domain PF00645 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region contains similarity to Interpro domain IPR001510 (Zinc finger, PARP-type)
12	T03G11.6	T03G11.6	n/a	chrX 5,178,330	contains similarity to Pfam domains PF05219 (DREV methyltransferase) , PF08242 (Methyltransferase domain) contains similarity to Interpro domains IPR013217 (Methyltransferase type 12), IPR007884 (DREV methyltransferase)
13	F53F4.3	F53F4.3	n/a	chrV 13,592,537	F53F4.3 encodes a putative alpha-tubulin folding cofactor B, orthologous to human CKAP1 (OMIM:601303); F53F4.3 is dispensable in early embryos for microtubule nucleation or elongation, and has no obvious function in mass RNAi assays.
14	Y47H9C.8	Y47H9C.8	n/a	chrI 11,895,073	contains similarity to Streptococcus pneumoniae Magnesium transporter, CorA family.; TR:Q97SX8
15	F21H12.1	F21H12.1	n/a	chrII 6,098,704	contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
16	syn-3	F55A11.2	n/a	chrV 11,766,040	C. elegans SYN-3 protein; contains similarity to Pfam domains PF00804 (Syntaxin) , PF05739 (SNARE domain) contains similarity to Interpro domains IPR010989 (t-SNARE), IPR006011 (Syntaxin, N-terminal), IPR000727 (Target SNARE coiled-coil region), IPR006012 (Syntaxin/epimorphin, conserved site)
17	F20D1.2	F20D1.2	n/a	chrX 14,972,677	contains similarity to Pfam domain PF00566 TBC domain contains similarity to Interpro domains IPR001763 (Rhodanese-like), IPR000195 (RabGAP/TBC)
18	C41H7.3	C41H7.3	n/a	chrII 3,006,666	contains similarity to Pfam domain PF03353 DUF278 contains similarity to Interpro domain IPR005020 (Protein of unknown function DUF278)
19	K08D10.1	K08D10.1	n/a	chrIV 4,182,875	contains similarity to Pfam domain PF06918 Protein of unknown function (DUF1280) contains similarity to Interpro domain IPR009689 (Protein of unknown function DUF1280)
20	B0001.5	B0001.5	n/a	chrIV 12,142,216	contains similarity to Saccharomyces cerevisiae Gtpase-activating protein activity toward the essential bud-site assembly GTPase Cdc42; SGD:YPL115C
21	B0035.11	B0035.11	n/a	chrIV 11,328,468	contains similarity to Pfam domain PF04004 Leo1-like protein contains similarity to Interpro domain IPR007149 (Leo1-like protein)
22	F32B6.3	F32B6.3	n/a	chrIV 9,883,182	contains similarity to Pfam domains PF02840 (Prp18 domain) , PF08799 (pre-mRNA processing factor 4 (PRP4) like) contains similarity to Interpro domains IPR014906 (Pre-mRNA processing factor 4 (PRP4) like), IPR003648 (Splicing factor motif), IPR004098 (Prp18)
23	tac-1	Y54E2A.3	n/a	chrII 14,753,292	tac-1 encodes the sole C. elegans member of the transforming acidic coiled-coil (TACC) protein family whose members contain highly conserved C-terminal coiled-coil domains; during early embryogenesis, TAC-1 activity is essential for such microtubule-based processes as pronuclear migration and mitotic spindle elongation; TAC-1 interacts in vivo with, and mutually stabilizes, ZYG-9, a microtubule-associated protein (MAP) also required for pronuclear migration; TAC-1 also interacts with ZYG-8, a kinase domain-containing MAP required for proper spindle positioning during anaphase of the first embryonic cell division; TAC-1 is a core component of centrosomes, and also localizes to the meiotic spindle poles, the mitotic spindle, and the cytoplasm.
24	F52C9.7	F52C9.7	n/a	chrIII 5,309,798	contains similarity to Interpro domain IPR002226 (Catalase)
25	T24C4.7	T24C4.7	n/a	chrIII 893,471	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold), IPR007087 (Zinc finger, C2H2-type)
26	F54C4.1	F54C4.1	n/a	chrIII 88,394	contains similarity to Drosophila melanogaster Flybase gene name is mRpL40-PA;; FLYBASE:CG5242
27	F22B5.10	F22B5.10	n/a	chrII 8,467,514	contains similarity to Pfam domain PF05809 Eukaryotic protein of unknown function (DUF841) contains similarity to Interpro domain IPR008559 (Protein of unknown function DUF841, eukaryotic)
28	rnp-3	K08D10.3	n/a	chrIV 4,175,171	rnp-3 encodes the small nuclear ribonucleoprotein (snRNP)-associated protein RNP-3/U2B''; genetically, rnp-3 appears to function redundantly with rnp-2/U1A: loss of rnp-3 activity alone results in low levels of embryonic and total lethality, while animals doubly mutant for rnp-3 and rnp-2/U1A show much higher levels of embryonic and total lethality; in addition, animals doubly mutant for SAP-1/U2A' and RNP-3/U2B'', display a much more severe phenotype than either single mutation, indicating that in vivo, these proteins have some independent functions; immunoprecipitation experiments indicate that RNP-3 associates with U2 RNA in vivo and that this association does not require the presence of SAP-1/U2A'.
29	C44H4.4	C44H4.4	n/a	chrX 14,586,632	contains similarity to Homo sapiens 155 kDa protein; ENSEMBL:ENSP00000381978
30	F17A9.2	F17A9.2	n/a	chrV 6,111,285	contains similarity to Pfam domains PF04676 (Protein similar to CwfJ C-terminus 2) , PF04677 (Protein similar to CwfJ C-terminus 1) contains similarity to Interpro domains IPR006768 (Protein similar to CwfJ, C-terminal 1), IPR006767 (Protein similar to CwfJ, C-terminal 2), IPR011146 (Histidine triad-like motif)
31	C27A12.9	C27A12.9	n/a	chrI 6,064,908	contains similarity to Pfam domain PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase contains similarity to Interpro domains IPR017849 (Alkaline phosphatase-like, alpha/beta/alpha), IPR002591 (Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase), IPR017850 (Alkaline-phosphatase-like, core domain)
32	bub-1	R06C7.8	n/a	chrI 7,253,581	bub-1 encodes a serine/threonine kinase orthologous to Saccharomyces cerevisiae BUB1 which is required for proper function of the mitotic spindle assembly checkpoint and human BUB1 (OMIM:602452) which is mutated in some colorectal cancers; BUB-1 activity is required at several stages of development, including embryogenesis; BUB-1 is expressed predominantly in the anterior of the embryo and in hypodermal seam cells during the L1 and L2 larval stages.
33	npp-11	F53F10.5	n/a	chrI 3,819,703	C. elegans NPP-11 protein; contains similarity to Interpro domains IPR003072 (Orphan nuclear receptor, NOR1 type), IPR000104 (Antifreeze protein, type I), IPR001778 (Pollen allergen Poa pIX/Phl pVI, C-terminal), IPR007758 (Nucleoporin, Nsp1-like, C-terminal)
34	R17.2	R17.2	n/a	chrIII 10,842,361	contains similarity to Pfam domain PF03372 Endonuclease/Exonuclease/phosphatase family contains similarity to Interpro domain IPR005135 (Endonuclease/exonuclease/phosphatase)
35	K08F11.2	K08F11.2	n/a	chrIV 4,718,190	contains similarity to Pfam domain PF06918 Protein of unknown function (DUF1280) contains similarity to Interpro domain IPR009689 (Protein of unknown function DUF1280)
36	C08B11.8	C08B11.8	n/a	chrII 8,040,793	contains similarity to Pfam domain PF03155 ALG6, ALG8 glycosyltransferase family contains similarity to Interpro domain IPR004856 (ALG6, ALG8 glycosyltransferase)
37	ger-1	R01H2.5	n/a	chrIII 7,066,371	C. elegans GER-1 protein; contains similarity to Pfam domain PF01370 NAD dependent epimerase/dehydratase family contains similarity to Interpro domains IPR001509 (NAD-dependent epimerase/dehydratase), IPR002347 (Glucose/ribitol dehydrogenase), IPR016040 (NAD(P)-binding)
38	Y38C9A.1	Y38C9A.1	n/a	chrV 112,782	contains similarity to Leishmania major strain Friedlin Proteophosphoglycan ppg4.; TR:Q4FX63
39	M03C11.8	M03C11.8	n/a	chrIII 10,432,042	contains similarity to Pfam domains PF00271 (Helicase conserved C-terminal domain) , PF00176 (SNF2 family N-terminal domain) contains similarity to Interpro domains IPR002048 (Calcium-binding EF-hand), IPR000330 (SNF2-related), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
40	eif-3.E	B0511.10	n/a	chrI 10,641,393	eif-3.E encodes the C. elegans ortholog of the translation initiation factor 3 subunit e (eIF3e/Int-6); by homology, EIF-3.E is predicted to be a component of three different protein complexes, the eIF3 translation initiation factor, the 26S proteasome, and the COP9 signalosome; such association suggests that EIF-3.E may serve as a regulatory factor that coordinates the translational and degradative activities of these various complexes; in C. elegans, large-scale RNAi screens indicate that eif-3.E is required for embryonic, larval, and germline development, as well as proper vulval morphogenesis.
41	prp-17	F49D11.1	n/a	chrI 10,938,676	C. elegans PRP-17 protein; contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR011042 (Six-bladed beta-propeller, TolB-like), IPR015943 (WD40/YVTN repeat-like)
42	ZK1010.3	ZK1010.3	n/a	chrIII 12,979,542	contains similarity to Pfam domain PF06229 FRG1-like family contains similarity to Interpro domains IPR010414 (FRG1-like), IPR008999 (Actin-crosslinking proteins)
43	git-1	F14F3.2	n/a	chrX 10,526,597	C. elegans GIT-1 protein; contains similarity to Pfam domains PF01412 (Putative GTPase activating protein for Arf) , PF00023 (Ankyrin repeat) (2)contains similarity to Interpro domains IPR013724 (Spa2 homology (SHD) of GIT), IPR001164 (Arf GTPase activating protein), IPR002110 (Ankyrin)
44	T07A9.1	T07A9.1	n/a	chrIV 384,318	contains similarity to Homo sapiens Protein; VG:OTTHUMP00000025811
45	tag-72	C25A1.3	n/a	chrI 10,160,921	C. elegans TAG-72 protein; contains similarity to Pfam domains PF03291 (mRNA capping enzyme) , PF08242 (Methyltransferase domain) , PF08241 (Methyltransferase domain) contains similarity to Interpro domains IPR004971 (mRNA capping enzyme, large subunit), IPR016899 (mRNA (guanine-N(7))-methyltransferase), IPR002296 (N6 adenine-specific DNA methyltransferase, N12 class), IPR013217 (Methyltransferase type 12), IPR013216 (Methyltransferase type 11)
46	sec-3	F52E4.7	n/a	chrX 3,097,634	C. elegans SEC-3 protein ; contains similarity to Danio rerio Exocyst complex component 1.; TR:Q7T2A6
47	T07F12.4	T07F12.4	n/a	chrX 4,897,382	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
48	F31D4.2	F31D4.2	n/a	chrV 20,838,947	contains similarity to Pfam domain PF01937 Protein of unknown function DUF89 contains similarity to Interpro domains IPR000408 (Regulator of chromosome condensation, RCC1), IPR002791 (Protein of unknown function DUF89)
49	Y106G6D.7	Y106G6D.7	n/a	chrI 10,126,327	contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR000694 (Proline-rich region), IPR012677 (Nucleotide-binding, alpha-beta plait), IPR000504 (RNA recognition motif, RNP-1)
50	set-32	C41G7.4	n/a	chrI 9,520,403	set-32 encodes a divergent histone H3 lysine-9 (H3K9) methyltransferase homolog with a SET domain; SET-32 has no obvious non-nematode orthologs, but several paralogs (SET-6, SET-13, SET-15, SET-19, SET-20, and SET-21); set-32(ok1457) has no obvious mutant phenotype, and SET-32 has no obvious function in mass RNAi assays.