UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	K12B6.2	K12B6.2	0	chrV 6,283,126	contains similarity to Pfam domain PF07782 DC-STAMP-like protein contains similarity to Interpro domain IPR012858 (DC-STAMP-like)
2	Y43F8C.5	Y43F8C.5	n/a	chrV 19,631,978	contains similarity to Dictyostelium discoideum Myb-like protein (Fragment).; SW:MYBH_DICDI
3	ZC204.1	ZC204.1	n/a	chrII 1,666,906	contains similarity to Pfam domain PF02520 Domain of unknown function DUF148 contains similarity to Interpro domain IPR003677 (Protein of unknown function DUF148)
4	R13A1.3	R13A1.3	n/a	chrIV 7,207,074	contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
5	F45E1.3	F45E1.3	n/a	chrX 7,987,677	contains similarity to Pfam domain PF00702 haloacid dehalogenase-like hydrolase contains similarity to Interpro domain IPR005834 (Haloacid dehalogenase-like hydrolase)
6	F20B6.6	F20B6.6	n/a	chrX 4,201,908	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domain IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type)
7	D1022.5	D1022.5	n/a	chrII 7,458,058
8	pax-3	F27E5.2	n/a	chrII 10,149,568	pax-3 encodes a divergent paired-like homeodomain protein that does not belong to the Q50, K50, or S50 classes; PAX-3 is required for locomotion and vulval development; pax-3(RNAi) animals have consistent Pvl and Unc phenotypes (as well as less consistent Bmd, Rup, and Stp phenotypes).
9	T08G11.2	T08G11.2	n/a	chrI 8,919,920	T08G11.2 encodes a nematode-specific sperm protein, required for a normally high ovulation rate, that interacts with EGL-32; despite not being EGL-32, and although T08G11.2(tm336) complements egl-32(n155), T08G11.2 can partially rescue egl-32 mutants when expressed transgenically, implying that T08G11.2 can be a nonorthologous replacement for EGL-32 function in vivo; T08G11.2 has an SH2 motif, but this motif lacks a critical arginine residue; T08G11.2 has no obvious non-nematode homologs, but is paralogous to four other C. elegans proteins (B0207.11, F42G4.6, F44F4.10, and Y81G3A.1); T08G11.2(tm336) hermaphrodites have a lowered ovulation rate (and thus a lowered rate of egg-laying), retaining significantly fewer eggs than wild-type, yet also retaining late-stage embryos; T08G11.2 has no obvious phenotype in mass RNAi experiments, possibly because of genetic redundancy with its paralogs; T08G11.2 expression is strongly enriched in spermatogenesis.
10	ZK550.1	ZK550.1	n/a	chrIV 17,240,852	contains similarity to Pfam domain PF03062 MBOAT family contains similarity to Interpro domain IPR004299 (Membrane bound O-acyl transferase, MBOAT)
11	B0252.1	B0252.1	n/a	chrII 6,921,631	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR008266 (Tyrosine protein kinase, active site)
12	col-8	F11H8.3	n/a	chrIII 7,020,027	col-8 encodes a collagen, individually dispensable for viability and gross morphology, which is specifically expressed in dauers and adults but not in eggs or L4 larvae, like col-7, col-18, and col-19; the amino- and carboxyl-terminal cysteine-rich regions of COL-8 are most closely related to those of COL-19, COL-35, and COL-39.
13	fat-7	F10D2.9	n/a	chrV 7,152,237	fat-7 encodes an essential delta-9 fatty acid desaturase that is required for the synthesis of monounsaturated fatty acids; fat-7 can substitute for the functions of the other two fatty acid desaturases, fat-5 and fat-6; RNA interference has shown that fat-7 is required for viability and normal growth.
14	C10G11.1	C10G11.1	n/a	chrI 6,307,930
15	C32D5.11	C32D5.11	n/a	chrII 6,354,177	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
16	clec-148	F40G9.10	n/a	chrIII 175,220	C. elegans CLEC-148 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR002352 (Eosinophil major basic protein), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
17	T25B2.1	T25B2.1	n/a	chrX 6,175,044	contains similarity to Pfam domains PF00620 (RhoGAP domain) , PF00130 (Phorbol esters/diacylglycerol binding domain (C1 domain)) contains similarity to Interpro domains IPR001060 (Cdc15/Fes/CIP4), IPR008936 (Rho GTPase activation protein), IPR000533 (Tropomyosin), IPR002219 (Protein kinase C, phorbol ester/diacylglycerol binding), IPR000695 (H+ transporting ATPase, proton pump), IPR000198 (RhoGAP)
18	R05D3.3	R05D3.3	n/a	chrIII 8,365,486
19	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
20	F09C12.2	F09C12.2	n/a	chrII 5,111,113	F09C12.2 encodes a kinase most closely related to mitogen-activated protein (MAP) kinases; as loss of F09C12.2 activity via mutation or large-scale RNAi results in no obvious defects, the precise role of F09C12.2 in C. elegans development and/or behavior is not yet known.
21	B0507.7	B0507.7	n/a	chrV 8,757,284	contains similarity to Pfam domains PF04960 (Glutaminase) , PF00023 (Ankyrin repeat) (2)contains similarity to Interpro domains IPR015868 (Glutaminase, core), IPR007043 (Glutaminase), IPR012338 (Beta-lactamase-type transpeptidase fold), IPR002110 (Ankyrin)
22	nhr-133	F44C8.8	n/a	chrV 2,211,309	C. elegans NHR-133 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
23	F21F8.2	F21F8.2	n/a	chrV 8,275,167	contains similarity to Pfam domain PF00026 Eukaryotic aspartyl protease contains similarity to Interpro domains IPR009007 (Peptidase aspartic, catalytic), IPR001461 (Peptidase A1)
24	ZK337.2	ZK337.2	n/a	chrI 14,977,996	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007086 (Zinc finger, C2H2-subtype), IPR013087 (Zinc finger, C2H2-type/integrase, DNA-binding), IPR003656 (Zinc finger, BED-type predicted), IPR007087 (Zinc finger, C2H2-type)
25	ZK666.2	ZK666.2	n/a	chrII 10,471,714	contains similarity to Homo sapiens ASH1; ENSEMBL:ENSP00000265206
26	T28F4.4	T28F4.4	n/a	chrI 7,488,371	contains similarity to Brugia malayi Putative uncharacterized protein BMBAC01P19.05a.; TR:Q8IHI4
27	F42A9.3	F42A9.3	n/a	chrIV 8,617,701
28	F38B6.2	F38B6.2	n/a	chrX 6,699,255	contains similarity to Interpro domain IPR006150 (Cysteine-rich repeat)
29	F43G9.4	F43G9.4	n/a	chrI 8,611,732	contains similarity to Brugia malayi Putative uncharacterized protein BMBAC01P19.03a.; TR:Q8IHI9
30	asb-1	F35G12.10	n/a	chrIII 4,595,209	asb-1 encodes the B subunit of the membrane-bound F0 proton channel portion of ATP synthase (mitochondrial respiratory chain [MRC] complex V) that is closely similar to its paralog ASB-2; asb-1 activity is required for embryonic viability and for normal proliferation of germline cells, specifically their progression to meiosis; in addition, asb-1 is required for response to hermaphrodite contact, the first step in a series of stereotypical male mating behaviors; expression of asb-1 mRNA is enriched in the germline and an ASB-1::GFP fusion localizes to mitochondria and to cilia of the male-specific CEM neurons.
31	msp-63	K05F1.7	n/a	chrII 5,797,240	msp-63 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.
32	C05B5.2	C05B5.2	n/a	chrIII 9,999,425	contains similarity to Agrobacterium tumefaciens Peptide synthetase.; TR:Q8UBE4
33	T28D6.3	T28D6.3	n/a	chrIII 11,367,475	contains similarity to Arabidopsis thaliana Hypothetical protein LCR14 precursor.; TR:P82729
34	R06A10.1	R06A10.1	n/a	chrI 1,087,211	contains similarity to Interpro domain IPR016196 (MFS general substrate transporter)
35	W09C3.1	W09C3.1	n/a	chrI 4,718,600	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
36	ZK945.7	ZK945.7	n/a	chrII 10,107,878	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8IAV6
37	nspa-9	C40H5.1	n/a	chrX 11,739,026	C. elegans NSPA-9 protein ;
38	srn-1	K12B6.5	n/a	chrV 6,285,660	C. elegans SRN-1 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
39	C05D2.3	C05D2.3	n/a	chrIII 5,616,047	C05D2.3 generally resembles aromatic-L-amino-acid/L-histidine decarboxylases; however, its predicted protein sequence lacks six residues critical for AADC function; C05D2.3 is dispensable in mass RNAi assays.
40	C07E3.3	C07E3.3	n/a	chrII 10,355,550	contains similarity to Ambrosia artemisiifolia Pollen allergen Amb a 1.2 precursor (Antigen E) (Antigen Amb a I).; SW:MP12_AMBAR
41	col-51	T28F2.8	n/a	chrI 3,654,613	col-51 encodes a cuticle collagen.
42	W02D9.10	W02D9.10	n/a	chrI 12,551,930
43	F47B3.7	F47B3.7	n/a	chrI 3,969,089	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase)
44	ZK218.11	ZK218.11	n/a	chrV 17,107,962	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
45	F15E6.4	F15E6.4	n/a	chrIV 4,291,666
46	T20D4.7	T20D4.7	n/a	chrV 3,409,192	contains similarity to Pfam domains PF08534 (Redoxin) , PF00578 (AhpC/TSA family) contains similarity to Interpro domains IPR011594 (Thioredoxin-like), IPR013740 (Redoxin), IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR000866 (Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen), IPR006662 (Thioredoxin-related)
47	fbxb-86	T27E9.8	n/a	chrIII 13,478,975	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
48	F35H8.4	F35H8.4	n/a	chrII 9,559,658	contains similarity to Streptococcus pyogenes Hypothetical protein.; TR:Q8P0S2
49	ZC8.6	ZC8.6	n/a	chrX 4,985,068	contains similarity to Pfam domain PF00454 Phosphatidylinositol 3- and 4-kinase contains similarity to Interpro domain IPR000403 (Phosphatidylinositol 3- and 4-kinase, catalytic)
50	lgc-51	F12B6.3	n/a	chrI 2,244,756	C. elegans LGC-51 protein; contains similarity to Pfam domains PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) , PF02932 (Neurotransmitter-gated ion-channel transmembrane region) contains similarity to Interpro domains IPR002289 (Gamma-aminobutyric-acid A receptor, beta subunit), IPR006028 (Gamma-aminobutyric acid A receptor), IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding), IPR006029 (Neurotransmitter-gated ion-channel transmembrane region)