UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	K11G9.2	K11G9.2	0	chrV 6,675,280	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domain IPR002018 (Carboxylesterase, type B)
2	fbxa-65	C17B7.11	n/a	chrV 3,345,912	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
3	C05E11.7	C05E11.7	n/a	chrX 4,583,603
4	math-8	C16C4.13	n/a	chrII 1,888,192	C. elegans MATH-8 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
5	T07G12.3	T07G12.3	n/a	chrIV 10,535,145	contains similarity to Pfam domain PF02995 Protein of unknown function (DUF229) contains similarity to Interpro domains IPR017849 (Alkaline phosphatase-like, alpha/beta/alpha), IPR004245 (Protein of unknown function DUF229), IPR017850 (Alkaline-phosphatase-like, core domain)
6	F55C12.6	F55C12.6	n/a	chrII 5,875,271	contains similarity to Pfam domain PF06852 Protein of unknown function (DUF1248) contains similarity to Interpro domain IPR009658 (Protein of unknown function DUF1248)
7	pcp-2	F23B2.12	n/a	chrIV 9,162,862	C. elegans PCP-2 protein; contains similarity to Pfam domain PF05577 Serine carboxypeptidase S28 contains similarity to Interpro domains IPR008758 (Peptidase S28), IPR000258 (Bacterial ice-nucleation proteins octamer repeat)
8	gst-42	D1053.1	n/a	chrX 11,727,007	gst-42 is orthologous to the human gene GLUTATHIONE TRANSFERASE ZETA-1 (also known as MALEYLACETOACETATE ISOMERASE; GSTZ1; OMIM:603758), which when mutated is thought to lead to a variety of type I tyrosinemia.
9	nhr-267	H22D14.1	n/a	chrIV 9,285,626	C. elegans NHR-267 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
10	T18D3.3	T18D3.3	n/a	chrX 12,465,679	contains similarity to Pfam domain PF01545 Cation efflux family contains similarity to Interpro domains IPR002524 (Cation efflux protein), IPR000425 (Major intrinsic protein)
11	ZC190.2	ZC190.2	n/a	chrV 8,682,033	contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domains IPR004151 (C. elegans Sre G protein-coupled chemoreceptor), IPR000366 (Fungal pheromone mating factor STE2 GPCR)
12	C31E10.7	C31E10.7	n/a	chrX 14,002,346	C31E10.7 is orthologous to the human gene UNKNOWN (PROTEIN FOR MGC:10230) (CYB5; OMIM:250790), which when mutated leads to disease.
13	ZK673.1	ZK673.1	n/a	chrII 10,444,162	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domains IPR000104 (Antifreeze protein, type I), IPR001778 (Pollen allergen Poa pIX/Phl pVI, C-terminal), IPR003582 (Metridin-like ShK toxin)
14	lrs-1	R74.1	n/a	chrIII 4,184,221	lrs-1 encodes a predicted cytoplasmic leucyl-tRNA synthetase (LeuRS), a class I aminoacyl-tRNA synthetase that catalyzes the attachment of leucine to its cognate tRNA and is thus required for protein biosynthesis; LRS-1 activity is required for embryonic, larval, and germline development, as well as normal body morphology and rates of postembryonic growth.
15	pcp-1	ZK112.1	n/a	chrIII 7,759,923	C. elegans PCP-1 protein; contains similarity to Pfam domain PF05577 Serine carboxypeptidase S28 contains similarity to Interpro domain IPR008758 (Peptidase S28)
16	pps-1	T14G10.1	n/a	chrIV 10,163,166	pps-1 is orthologous to human PAPSS1 (OMIM:603262) and human PAPSS2 (OMIM:603005, mutated in spondyloepimetaphyseal dysplasia).
17	pmp-4	T02D1.5	n/a	chrIV 17,404,001	The pmp-4 gene encodes a homolog of human ALD, which when mutated leads to X-linked adrenoleukodystrophy (OMIM:300100).
18	srz-64	Y57G7A.7	n/a	chrII 1,291,002	C. elegans SRZ-64 protein ;
19	rab-11.1	F53G12.1	n/a	chrI 109,369	rab-11.1 encodes a small GTPase homologous to the Rab GTPases that function in endocytosis, membrane fusion, and vesicular trafficking events; RAB-11.1 activity is required for completion of the final stages of cytokinesis during early embryogenesis and for efficient uptake of yolk proteins during oocyte development; RAB-11.1 is also required for normal peripheral localization of nuclei in the synctial germ cell in the ovary.
20	mig-23	R07E4.4	n/a	chrX 5,947,305	mig-23 encodes a nucleoside diphosphatase (NDPase); during larval development, MIG-23 activity is required, in body wall muscle cells, for proper dorsalward migration of the gonadal distal tip cells (DTCs) and gonad morphogenesis via regulation of MIG-17 N-glycosylation; animals lacking MIG-23 exhibit weaker UDP-, ADP-, and GDP-hydrolysing activity and when expressed in yeast lacking apyrase genes, MIG-23 can rescue NDPase activity; when expressed in body wall muscle under the control of the unc-54 promoter, MIG-23 rescues DTC migration defects and shows a punctate cytoplasmic expression pattern similar to that of Golgi enzymes.
21	apm-1	F55A12.7	n/a	chrI 5,343,455	The apm-1 gene encodes an adaptin: specifically, it encodes an ortholog of the mu1-II subunit of adaptor protein complex 1 (AP-1).
22	col-111	F29B9.9	n/a	chrIV 4,656,697	C. elegans COL-111 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (3)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat)
23	srxa-2	F56D5.10	n/a	chrIV 9,423,882	C. elegans SRXA-2 protein; contains similarity to Pfam domain PF03383 Caenorhabditis serpentine receptor-like protein, class xa contains similarity to Interpro domain IPR005047 (Protein of unknown function DUF286, G protein-coupled receptor-like putative Caenorhabditis species)
24	K09C4.10	K09C4.10	n/a	chrX 3,278,116	contains similarity to Staphylococcus aureus Serine-rich adhesin for platelets precursor (Staphylococcus aureusssurface protein A).; SW:Q7A362
25	F38B6.4	F38B6.4	n/a	chrX 6,677,310	contains similarity to Pfam domains PF02844 (Phosphoribosylglycinamide synthetase, N domain) , PF02769 (AIR synthase related protein, C-terminal domain) , PF02843 (Phosphoribosylglycinamide synthetase, C domain) , PF01071 (Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain) , PF00551 (Formyl transferase) , PF00586 (AIR synthase related protein, N-terminal domain) contains similarity to Interpro domains IPR016185 (PreATP-grasp-like fold), IPR011761 (ATP-grasp fold), IPR004733 (Phosphoribosylformylglycinamidine cyclo-ligase), IPR002376 (Formyl transferase, N-terminal), IPR016188 (PurM, N-terminal-like), IPR000728 (AIR synthase related protein), IPR004607 (Phosphoribosylglycinamide formyltransferase), IPR013815 (ATP-grasp fold, subdomain 1), IPR010918 (AIR synthase related protein, C-terminal), IPR013816 (ATP-grasp fold, subdomain 2), IPR013817 (Pre-ATP-grasp fold), IPR011054 (Rudiment single hybrid motif), IPR000115 (Phosphoribosylglycinamide synthetase)
26	nas-38	F57C12.1	n/a	chrX 560,901	C. elegans NAS-38 protein; contains similarity to Pfam domains PF00431 (CUB domain) , PF00090 (Thrombospondin type 1 domain) , PF01400 (Astacin (Peptidase family M12A)) contains similarity to Interpro domains IPR000884 (Thrombospondin, type I), IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR001506 (Peptidase M12A, astacin), IPR006026 (Peptidase, metallopeptidases), IPR000859 (CUB), IPR013032 (EGF-like region, conserved site)
27	C36B7.6	C36B7.6	n/a	chrX 7,098,999	contains similarity to Pfam domain PF05602 Cleft lip and palate transmembrane protein 1 (CLPTM1) contains similarity to Interpro domain IPR008429 (Cleft lip and palate transmembrane 1)
28	elt-2	C33D3.1	n/a	chrX 10,482,266	elt-2 encodes a GATA-type transcription factor most similar to the vertebrate GATA4-6 transcription factors required for cardiac and endoderm development (OMIM:601656, 600576); in C. elegans, ELT-2 is required redundantly with ELT-7 for initiating and maintaining terminal differentiation of the intestine; ELT-2 is expressed solely in the intestine, beginning embryonically at the 2E-cell stage and continuing in all intestinal cells throughout the life of the animal; in the regulatory hierarchy controlling endoderm development, ELT-2 lies downstream of the maternal regulators SKN-1 and POP-1 and the embryonic GATA factors MED-1/-2, and END-1/-3; in turn, ELT-2, along with ELT-7, likely regulates transcription of a number of intestine-specific terminal differentiation genes such as ges-1, ifb-2, pha-4, and the stress-induced mtl-2; ELT-2 also positively autoregulates, presumably to ensure maintenance of intestinal differentiation
29	H34C03.2	H34C03.2	n/a	chrIV 6,759,933	contains similarity to Pfam domain PF00443 Ubiquitin carboxyl-terminal hydrolase contains similarity to Interpro domains IPR001394 (Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2), IPR006615 (Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)
30	rer-1	F46C5.8	n/a	chrII 8,811,744	C. elegans RER-1 protein; contains similarity to Pfam domain PF03248 Rer1 family contains similarity to Interpro domain IPR004932 (Retrieval of early ER protein Rer1)
31	C34F6.8	C34F6.8	n/a	chrX 11,216,944	contains similarity to Pfam domain PF00180 Isocitrate/isopropylmalate dehydrogenase contains similarity to Interpro domains IPR004790 (Isocitrate dehydrogenase NADP-dependent, eukaryotic), IPR001804 (Isocitrate/isopropylmalate dehydrogenase)
32	F42A10.5	F42A10.5	n/a	chrIII 6,172,231	contains similarity to Interpro domain IPR003072 (Orphan nuclear receptor, NOR1 type)
33	Y43F8C.4	Y43F8C.4	n/a	chrV 19,627,836	contains similarity to Homo sapiens 90 kDa protein; VG:OTTHUMP00000182483
34	T11G6.4	T11G6.4	n/a	chrIV 10,850,812	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR008075 (Lipocalin-1 receptor), IPR016196 (MFS general substrate transporter)
35	pgp-13	F22E10.2	n/a	chrX 12,741,422	pgp-13 encodes a member of the ABC transporter family with high similarity to the vertebrate MDR (multidrug resistance) family; PGP-13 is predicted to function as a transmembrane protein that couples energy to transport of various molecules across membranes, but as loss of pgp-13 activity via large-scale RNAi screens does not result in any obvious defects, the precise role of pgp-13 in C. elegans development and/or behavior is not yet known; pgp-13 promoter-gfp fusion proteins are expressed in larvae and adults in the posterior intestine and the amphids.
36	F46C5.9	F46C5.9	n/a	chrII 8,809,612	contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR011042 (Six-bladed beta-propeller, TolB-like), IPR015943 (WD40/YVTN repeat-like)
37	arx-5	Y37D8A.1	n/a	chrIII 12,817,350	arx-5 encodes the C. elegans ortholog of the p21Arc subunit of the actin-related protein (Arp) 2/3 complex.
38	fbxa-54	T12B5.2	n/a	chrIII 957,051	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
39	coq-8	C35D10.4	n/a	chrIII 4,865,152	coq-8 encodes a putative protein kinase orthologous to ABC1 (COQ8) from S. cerevisiae and UbiB from E. coli, and paralogous to C. elegans D2023.6 and its (uncharacterized) eukaryotic orthologs; COQ-8 is required for ubiquinone (coenzyme Q9) biosynthesis and for normally short lifespan; alternative hypotheses for COQ-8's biochemical function are that it is a 2-polyprenylphenol 6-hydroxylase, or that it may activate proteins necessary for monooxygenase activity via phosphorylation; coq-8 is expressed in several tissues during larval development, but in later adult life its expression is restricted to neurons; coq-8 mutants have slowed pharyngeal pumping, and eventually arrest as paralysed larvae before dying; coq-8(RNAi) animals have reduced levels of coenzyme Q9 and superoxide, and have abnormally long lifespans; coq-8 mutants are not rescued by dietary coenzyme Q.
40	F22G12.4	F22G12.4	n/a	chrI 13,157,287	contains similarity to Pfam domains PF01363 (FYVE zinc finger) , PF00023 (Ankyrin repeat) (17)contains similarity to Interpro domains IPR000306 (Zinc finger, FYVE-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR002110 (Ankyrin), IPR017455 (Zinc finger, FYVE-related), IPR011011 (Zinc finger, FYVE/PHD-type)
41	F13D2.1	F13D2.1	n/a	chrX 11,169,479	contains similarity to Interpro domain IPR008930 (Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)
42	F08B12.1	F08B12.1	n/a	chrX 11,388,875	F08B12.1 is orthologous to the human gene AC133-2 ANTIGEN (PROML1; OMIM:604365), which when mutated leads to disease.
43	R09F10.1	R09F10.1	n/a	chrX 8,324,257	contains similarity to Pfam domains PF08246 (Cathepsin propeptide inhibitor domain (I29)) , PF00112 (Papain family cysteine protease) contains similarity to Interpro domains IPR013128 (Peptidase C1A, papain), IPR000169 (Peptidase, cysteine peptidase active site), IPR013201 (Proteinase inhibitor I29, cathepsin propeptide), IPR000668 (Peptidase C1A, papain C-terminal)
44	snx-1	C05D9.1	n/a	chrX 1,130,709	C. elegans SNX-1 protein; contains similarity to Pfam domains PF09325 (Vps5 C terminal like) , PF00787 (PX domain) contains similarity to Interpro domains IPR001683 (Phox-like), IPR013822 (Signal recognition particle, SRP54 subunit, helical bundle), IPR015404 (Vps5 C terminal like)
45	C06G1.5	C06G1.5	n/a	chrX 16,640,570	contains similarity to Interpro domains IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand)
46	ZC504.3	ZC504.3	n/a	chrX 10,418,158	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR008351 (JNK MAP kinase), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
47	B0024.11	B0024.11	n/a	chrV 10,318,482	contains similarity to Pfam domain PF01142 tRNA pseudouridine synthase D (TruD) contains similarity to Interpro domains IPR001656 (tRNA pseudouridine synthase D), IPR011760 (tRNA pseudouridine synthase D, core), IPR017091 (tRNA pseudouridine synthase D, eukaryotic)
48	B0286.3	B0286.3	n/a	chrII 4,371,091	contains similarity to Pfam domains PF01259 (SAICAR synthetase) , PF00731 (AIR carboxylase) contains similarity to Interpro domains IPR001636 (SAICAR synthetase), IPR000031 (1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase), IPR013816 (ATP-grasp fold, subdomain 2)
49	tli-1	F25H2.1	n/a	chrI 10,536,634	C. elegans TLI-1 protein; contains similarity to Pfam domains PF00168 (C2 domain) , PF02845 (CUE domain) contains similarity to Interpro domains IPR003892 (Ubiquitin system component Cue), IPR009060 (UBA-like), IPR008973 (C2 calcium/lipid-binding region, CaLB), IPR000008 (C2 calcium-dependent membrane targeting)
50	C04E12.12	C04E12.12	n/a	chrV 3,390,139	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR000698 (Arrestin), IPR014752 (Arrestin, C-terminal), IPR011021 (Arrestin-like, N-terminal)