UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	cwp-4	K11D12.1	2e-97	chrV 5,055,031	cwp-4 encodes a protein with some similarity to mucins that is predicted to be secreted, and is alleged to be coexpressed with polycystins; CWP-4 is dispensable for viability and gross morphology in mass RNAi screens.
2	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
3	ZC84.3	ZC84.3	n/a	chrIII 9,188,742	contains similarity to Pfam domain PF02985 HEAT repeat contains similarity to Interpro domains IPR000357 (HEAT), IPR016024 (Armadillo-type fold)
4	ndx-1	T26E3.2	n/a	chrI 12,680,484	The ndx-1 gene encodes a NUDIX hydrolase.
5	vab-9	T22C8.8	n/a	chrII 8,636,902	vab-9 encodes a claudin homolog orthologous to human brain cell membrane protein 1 (BCMP1) and Drosophila CG6982; VAB-9 colocalizes with HMP-1 to an apical layer of the adherens junctions of all epithelial cells, one layer more apically than AJM-1; vab-9 mutants have disorganized F-actin at the adherens junction, implying that VAB-9 links junctions to circumferential actin filaments; VAB-9 is also expressed in the nerve ring; VAB-9 requires the cadherin HMR-1 to localize to the cell membrane, and both alpha-catenin (HMP-1) and beta-catenin (HMP-2) to remain at the cell junction after membrane localization.
6	F23A7.5	F23A7.5	n/a	chrX 16,233,076	contains similarity to Homo sapiens Isoform 3 of Cyclin-L1; VG:OTTHUMP00000173336
7	tag-224	B0496.8	n/a	chrIV 7,450,248	tag-224 encodes an ortholog of Drosophila CG6522-PA and of human LMCD1 and TESTIN; TAG-224 is dispensable for Wnt-directed planar cell polarity and the fully asymmetrical division of B.a versus B.p cells.
8	R09B5.11	R09B5.11	n/a	chrV 1,440,531	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005829 (Sugar transporter, conserved site), IPR005828 (General substrate transporter), IPR003663 (Sugar transporter), IPR016196 (MFS general substrate transporter)
9	T14C1.1	T14C1.1	n/a	chrX 14,408,600	T14C1.1 encodes a homolog of the functionally active Fmrf Receptor (FR; CG2114) of D. melanogaster; it is thus possible that T14C1.1 is a receptor for one of the FMRF-like neurotransmitters in C. elegans (e.g., FLP-1 through FLP-12).
10	elt-3	K02B9.4	n/a	chrX 13,939,895	The elt-3 gene encodes a GATA transcription factor expressed in the embryonic hypodermis; specifically, it is expressed in expressed in all of the major hypodermal cells except the lateral seam cells.
11	F54B11.9	F54B11.9	n/a	chrX 13,607,737	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8I5W3
12	lin-66	B0513.1	n/a	chrIV 13,891,003	lin-66 encodes an unfamiliar protein, with visible homologs only in nematodes, that was identified in screens for molecules that interact with GEX-3, a homolog of mammalian protein ligands of the small GTPase Rac1, that is essential for ventral enclosure during embryonic development; LIN-66 is expressed in body wall and vulval muscles, and is also detected in the intestine, neurons, and probably the hypodermis.
13	gcy-15	ZC239.7	n/a	chrII 3,194,642	gcy-15 encodes a membrane guanylyl cyclase.
14	ZK265.7	ZK265.7	n/a	chrI 8,265,494	contains similarity to Drosophila yakuba Salivary glue protein Sgs-3 precursor.; SW:P13728
15	F11A5.8	F11A5.8	n/a	chrV 16,208,396	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
16	F56C3.9	F56C3.9	n/a	chrX 1,392,907	contains similarity to Interpro domains IPR011333 (BTB/POZ fold), IPR013089 (Kelch related)
17	frm-3	H05G16.1	n/a	chrX 11,578,915	frm-3 encodes a protein containing a FERM domain (Band 4.1 family); expressed in a few cells in the head.
18	T02E1.8	T02E1.8	n/a	chrI 8,236,518
19	C37C3.11	C37C3.11	n/a	chrV 7,864,144
20	C06A5.5	C06A5.5	n/a	chrI 5,982,136
21	F47A4.5	F47A4.5	n/a	chrX 9,835,643	contains similarity to Pfam domains PF01734 (Patatin-like phospholipase) , PF00023 (Ankyrin repeat) (5)contains similarity to Interpro domains IPR016035 (Acyl transferase/acyl hydrolase/lysophospholipase), IPR001638 (Bacterial extracellular solute-binding protein, family 3), IPR002641 (Patatin), IPR002110 (Ankyrin), IPR001680 (WD40 repeat)
22	Y37A1B.6	Y37A1B.6	n/a	chrIV 14,038,988	contains similarity to Bacillus amyloliquefaciens Beta-glucanase (BglA) (Fragment).; TR:Q44651
23	irk-3	K04G11.5	n/a	chrX 14,356,108	C. elegans IRK-3 protein; contains similarity to Pfam domain PF01007 Inward rectifier potassium channel contains similarity to Interpro domains IPR013521 (Potassium channel, inwardly rectifying, Kir, conserved region 2), IPR014756 (Immunoglobulin E-set), IPR013518 (Potassium channel, inwardly rectifying, Kir, cytoplasmic), IPR001838 (Potassium channel, inwardly rectifying, Kir-like)
24	T12B3.1	T12B3.1	n/a	chrIV 7,383,567	contains similarity to Pfam domains PF00782 (Dual specificity phosphatase, catalytic domain) , PF00102 (Protein-tyrosine phosphatase) contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase), IPR000340 (Protein-tyrosine phosphatase, dual specificity), IPR000923 (Blue (type 1) copper domain)
25	M03F8.4	M03F8.4	n/a	chrV 5,932,159	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
26	C25E10.4	C25E10.4	n/a	chrV 9,034,575	contains similarity to Interpro domains IPR000802 (Arsenical pump membrane protein), IPR016196 (MFS general substrate transporter)
27	C55C3.2	C55C3.2	n/a	chrIV 5,707,741
28	K06A1.3	K06A1.3	n/a	chrII 6,442,625	contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domain IPR001507 (Endoglin/CD105 antigen)
29	F27E11.1	F27E11.1	n/a	chrV 3,464,980	contains similarity to Pfam domains PF01773 (Na+ dependent nucleoside transporter N-terminus) , PF07670 (Nucleoside recognition) , PF07662 (Na+ dependent nucleoside transporter C-terminus) contains similarity to Interpro domains IPR008276 (Concentrative nucleoside transporter), IPR002668 (Na+ dependent nucleoside transporter), IPR011657 (Na+ dependent nucleoside transporter, C-terminal), IPR011642 (Nucleoside recognition)
30	sto-2	F32A6.5	n/a	chrX 5,309,627	C. elegans STO-2 protein; contains similarity to Pfam domain PF01145 SPFH domain / Band 7 family contains similarity to Interpro domains IPR001107 (Band 7 protein), IPR001972 (Stomatin)
31	ZK688.7	ZK688.7	n/a	chrIII 7,911,165
32	F45E1.2	F45E1.2	n/a	chrX 8,003,850
33	clec-89	C09D1.2	n/a	chrI 4,072,314	C. elegans CLEC-89 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR003990 (Pancreatitis-associated protein), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
34	blmp-1	F25D7.3	n/a	chrI 10,411,592	C. elegans BLMP-1 protein; contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR001214 (SET), IPR015880 (Zinc finger, C2H2-like), IPR007086 (Zinc finger, C2H2-subtype), IPR013087 (Zinc finger, C2H2-type/integrase, DNA-binding), IPR003656 (Zinc finger, BED-type predicted), IPR007087 (Zinc finger, C2H2-type)
35	K10C8.2	K10C8.2	n/a	chrV 12,691,417	K10C8.2 encodes a homolog of the functionally active Fmrf Receptor (FR; CG2114) of D. melanogaster; it is thus possible that K10C8.2 is a receptor for one of the FMRF-like neurotransmitters in C. elegans (e.g., FLP-1 through FLP-12).
36	F22E5.1	F22E5.1	n/a	chrII 2,676,663	contains similarity to Pfam domain PF07801 Protein of unknown function (DUF1647) contains similarity to Interpro domain IPR012444 (Protein of unknown function DUF1647)
37	ptr-19	Y39A1B.2	n/a	chrIII 10,786,410	ptr-19 encodes an ortholog of Drosophila and human PTCHD3, which defines one of seven paralogous families of sterol sensing domain (SSD) proteins; PTR-19 is required for normal development in mass RNAi assays; PTR-19 is expressed in pharynx, hypodermis, nervous system (including head neurons), and other cells.
38	C30F12.6	C30F12.6	n/a	chrI 6,990,585	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR008365 (Prostanoid receptor), IPR002120 (Thyrotrophin-releasing hormone receptor), IPR009144 (Thyrotropin-releasing hormone receptor), IPR000276 (GPCR, rhodopsin-like)
39	glf-1	H04M03.4	n/a	chrIV 5,887,804	H04M03.4 encodes a UDP-galactopyranose mutase predicted to synthesize galactofuranose (Gal(f)) as a nucleotide sugar (UDP-Gal(f)); recombinant H04M03.4 has biochemical activity either in vivo (expressed in E. coli) or in vitro; orthologs of H04M03.4 are found in the urochordates Halocynthia and Ciona.
40	C09F12.2	C09F12.2	n/a	chrX 11,055,383	contains similarity to Tetrahymena thermophila SB210 Putative uncharacterized protein.; TR:Q23C46
41	K08E7.6	K08E7.6	n/a	chrIV 12,580,060	contains similarity to Aquifex aeolicus Probable DNA double-strand break repair rad50 ATPase.; SW:RA50_AQUAE
42	cyn-9	T27D1.1	n/a	chrIII 3,698,740	cyn-9 encodes a peptidyl prolyl cis-trans isomerase most similar to human cyclophilin G (OMIM:606093); CYN-9 likely functions as a catalyst in the folding and modification of cuticle collagens; a cyn-9::lacZ reporter is expressed in the syncytial hypodermis from early larval through adult stages; cyn-9 mRNA is expressed most strongly at the mid-L3 and mid-L4 larval stages, the intermoult period when collagens are synthesized.
43	T16A1.4	T16A1.4	n/a	chrII 2,081,787
44	srr-1	W07G4.6	n/a	chrV 13,051,818	C. elegans SRR-1 protein; contains similarity to Pfam domain PF03268 Caenorhabditis protein of unknown function, DUF267 contains similarity to Interpro domain IPR004950 (Protein of unknown function DUF267, Caenorhabditis species)
45	F23F1.3	F23F1.3	n/a	chrII 32,686
46	Y81G3A.3	Y81G3A.3	n/a	chrII 13,087,735	contains similarity to Pfam domains PF05773 (RWD domain) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR006575 (RWD), IPR016135 (Ubiquitin-conjugating enzyme/RWD-like), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR000276 (GPCR, rhodopsin-like)
47	nhr-207	R07B7.14	n/a	chrV 12,097,016	C. elegans NHR-207 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR001728 (Thyroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
48	lge-1	K09C8.4	n/a	chrX 10,968,138	C. elegans LGE-1 protein; contains similarity to Pfam domain PF01501 Glycosyl transferase family 8 contains similarity to Interpro domain IPR002495 (Glycosyl transferase, family 8)
49	Y39A3B.3	Y39A3B.3	n/a	chrIII 1,986,275
50	psa-1	Y113G7B.23	n/a	chrV 20,239,752	psa-1 encodes an ortholog of SWI3, a component of the SWI/SNF complex that is conserved from yeast to mammals and that is involved in chromatin remodeling; psa-1 is probably required during mitosis of the T cells for asymmetric cell division, and in addition, is required for embryonic and larval development, as well as normal levels of fertility; psa-1 exhibits strong genetic interactions with lin-35/Rb, as psa-1 larval lethality and sterility at 20 degrees C are greatly enhanced in lin-35;psa-1 double mutants.