UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	K11B4.1	K11B4.1	0	chrI 14,796,015	contains similarity to Interpro domain IPR007110 (Immunoglobulin-like)
2	rnf-121	C16C10.5	n/a	chrIII 4,169,952	C. elegans RNF-121 protein; contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011016 (Zinc finger, variant RING-type)
3	F49C12.9	F49C12.9	n/a	chrIV 9,315,482	contains similarity to Pfam domain PF00627 UBA/TS-N domain contains similarity to Interpro domains IPR009060 (UBA-like), IPR000449 (Ubiquitin-associated/translation elongation factor EF1B, N-terminal), IPR015940 (Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)
4	acl-8	T05H4.1	n/a	chrV 6,451,547	C. elegans ACL-8 protein; contains similarity to Pfam domain PF01553 Acyltransferase contains similarity to Interpro domain IPR002123 (Phospholipid/glycerol acyltransferase)
5	ppk-3	VF11C1L.1	n/a	chrX 12,972,222	C. elegans PPK-3 protein; contains similarity to Pfam domains PF01504 (Phosphatidylinositol-4-phosphate 5-Kinase) , PF01363 (FYVE zinc finger) contains similarity to Interpro domains IPR000306 (Zinc finger, FYVE-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR002498 (Phosphatidylinositol-4-phosphate 5-kinase, core), IPR016034 (Phosphatidylinositol-4-phosphate 5-kinase, core, subgroup), IPR002423 (Chaperonin Cpn60/TCP-1), IPR017455 (Zinc finger, FYVE-related), IPR011011 (Zinc finger, FYVE/PHD-type)
6	F25E5.1	F25E5.1	n/a	chrV 7,468,526	contains similarity to Interpro domain IPR009091 (Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)
7	tag-231	ZK430.2	n/a	chrII 4,421,285	C. elegans TAG-231 protein; contains similarity to Pfam domain PF00459 Inositol monophosphatase family contains similarity to Interpro domains IPR000760 (Inositol monophosphatase), IPR000146 (Inositol phosphatase/fructose-1,6-bisphosphatase)
8	K08F11.5	K08F11.5	n/a	chrIV 4,714,405	contains similarity to Pfam domains PF08356 (EF hand associated) , PF08355 (EF hand associated) , PF00071 (Ras family) , PF00036 (EF hand) (2), PF08477 (Miro-like protein) (2)contains similarity to Interpro domains IPR013566 (EF hand associated, type-1), IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand), IPR003577 (Ras small GTPase, Ras type), IPR013684 (Miro-like), IPR003578 (Ras small GTPase, Rho type), IPR005225 (Small GTP-binding protein), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR013753 (Ras), IPR006689 (ARF/SAR superfamily), IPR013567 (EF hand associated, type-2)
9	ubh-4	C08B11.7	n/a	chrII 8,038,864	C. elegans UBH-4 protein; contains similarity to Pfam domain PF01088 Ubiquitin carboxyl-terminal hydrolase, family 1 contains similarity to Interpro domains IPR001578 (Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1), IPR017390 (Ubiquitinyl hydrolase, UCH37 type)
10	H19N07.1	H19N07.1	n/a	chrV 11,111,736	contains similarity to Pfam domains PF03143 (Elongation factor Tu C-terminal domain) , PF03144 (Elongation factor Tu domain 2) , PF00009 (Elongation factor Tu GTP binding domain) contains similarity to Interpro domains IPR000795 (Protein synthesis factor, GTP-binding), IPR004160 (Translation elongation factor EFTu/EF1A, C-terminal), IPR004161 (Translation elongation factor EFTu/EF1A, domain 2), IPR009001 (Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)
11	ZK1098.7	ZK1098.7	n/a	chrIII 9,523,311	contains similarity to Drosophila melanogaster Flybase gene name is mRpS23-PA;; FLYBASE:CG31842
12	M02G9.1	M02G9.1	n/a	chrII 10,330,867	contains similarity to Pfam domain PF02363 Cysteine rich repeat contains similarity to Interpro domains IPR003341 (Cysteine rich repeat, tripleX), IPR015333 (Pollen allergen ole e 6)
13	mel-46	T06A10.1	n/a	chrIV 16,859,204	C. elegans MEL-46 protein; contains similarity to Pfam domains PF00270 (DEAD/DEAH box helicase) , PF00271 (Helicase conserved C-terminal domain) contains similarity to Interpro domains IPR011545 (DNA/RNA helicase, DEAD/DEAH box type, N-terminal), IPR000629 (RNA helicase, ATP-dependent, DEAD-box, conserved site), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR003593 (AAA+ ATPase, core), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
14	lbp-5	W02D3.7	n/a	chrI 6,731,777	lbp-5 encodes a predicted intracellular fatty acid binding protein (iFABP) that is most similar to the vertebrate muscle and heart FABPs; by homology, LBP-5 is predicted to function as an intracellular transporter for small hydrophobic molecules such as lipids and steroid hormones; loss of lbp-5 activity via large-scale RNAi screens indicates that, in C. elegans, LBP-5 is required for movement.
15	pfd-1	C08F8.1	n/a	chrIV 11,150,492	pfd-1 encodes a putative prefoldin subunit 1, orthologous to human PFDN1 (OMIM:604897), that is required for normal microtubule nucleation and growth, embryonic viability, distal tip cell (DTC) migration, and locomotion; PFD-1 is expressed cytoplasmically in most, if not all, tissues; pfd-1(RNAi) animals have sterile progeny and are uncoordinated, and pfd-1(RNAi) embryos show a reduced microtubule growth rate; pfd-1(gk526) or escaper pfd-1(RNAi) hermaphrodites exhibit detective DTC migration.
16	gly-13	B0416.6	n/a	chrX 9,295,081	gly-13 encodes an experimentally verified UDP-N-acetylglucosamine alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I (GnT I), that is the primary GnT I enzyme in vivo, and that can act on unusual substrates; gly-13 is expressed throughout development in many cell types; gly-13 has no obvious function in vivo, since a deletion allele of gly-13 is phenotypically normal even as a double or triple mutant with gly-12 and gly-14.
17	tag-135	D1054.15	n/a	chrV 10,807,021	C. elegans TAG-135 protein; contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR009146 (Groucho/transducin-like enhancer), IPR001680 (WD40 repeat), IPR011042 (Six-bladed beta-propeller, TolB-like), IPR015943 (WD40/YVTN repeat-like)
18	oxi-1	Y39A1C.2	n/a	chrIII 10,862,495	C. elegans OXI-1 protein; contains similarity to Pfam domain PF00632 HECT-domain (ubiquitin-transferase) contains similarity to Interpro domain IPR000569 (HECT)
19	ers-3	T07A9.2	n/a	chrIV 389,575	ers-3 encodes a a glutamine (E)/glutaminyl (Q) tRNA synthetase.
20	dog-1	F33H2.1	n/a	chrI 15,020,116	dog-1 encodes a predicted DEAH helicase, orthologous to the human BRCA1-binding protein BACH1 (OMIM:605882, mutated in early-onset breast cancer); DOG-1 is required for maintenance of polyguanine tracts of germline and somatic DNA, and is proposed to resolve the secondary structure that can occur in guanine-rich DNA during lagging-strand DNA synthesis.
21	mog-5	EEED8.5	n/a	chrII 5,402,615	The mog-5 gene encodes a DEAH helicase orthologous to the Drosophila CG8241, the human HRH1, and the S. cerevisiae PRP22 proteins.
22	prx-19	F54F2.8	n/a	chrIII 8,808,467	prx-19 is orthologous to the human gene PEROXISOMAL FARNESYLATED PROTEIN (PXF; OMIM:600279), which when mutated leads to peroxisome biogenesis (Zellweger) syndrome of complementation group J.
23	arl-1	F54C9.10	n/a	chrII 8,582,264	arl-1 encodes a member of the GTP-binding ADP-ribosylation factor family.
24	nid-1	F54F3.1	n/a	chrV 12,913,630	C. elegans NID-1 protein; contains similarity to Pfam domains PF00008 (EGF-like domain) (3), PF07645 (Calcium binding EGF domain) , PF06119 (Nidogen-like) , PF07474 (G2F domain) , PF01436 (NHL repeat) (2), PF00058 (Low-density lipoprotein receptor repeat class B) (4)contains similarity to Interpro domains IPR000033 (), IPR011061 (Proteinase inhibitor I14/I15, hirudin/antistatin), IPR000742 (EGF-like, type 3), IPR009017 (Green fluorescent protein-like), IPR006209 (EGF-like), IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR006210 (EGF), IPR003886 (Nidogen, extracellular region), IPR003944 (Protease-activated receptor 4), IPR001881 (EGF-like calcium-binding), IPR011042 (Six-bladed beta-propeller, TolB-like), IPR013032 (EGF-like region, conserved site), IPR006605 (G2 nidogen and fibulin G2F), IPR013091 (EGF calcium-binding), IPR015943 (WD40/YVTN repeat-like)
25	T01G5.1	T01G5.1	n/a	chrV 15,117,760	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
26	T07A9.10	T07A9.10	n/a	chrIV 391,835	contains similarity to Pfam domain PF00995 Sec1 family contains similarity to Interpro domain IPR001619 (Sec1-like protein)
27	his-3	T10C6.12	n/a	chrV 16,040,965	his-3 encodes an H2A histone; by homology, HIS-3 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-3 is a replication-dependent histone locus that resides in the HIS1 cluster on chromosome V.
28	C25H3.4	C25H3.4	n/a	chrII 5,692,793	contains similarity to Pfam domains PF01472 (PUA domain) , PF01253 (Translation initiation factor SUI1) contains similarity to Interpro domains IPR004521 (Uncharacterized domain 2), IPR015947 (PUA-like), IPR001950 (Translation initiation factor SUI1), IPR002478 (PUA)
29	K10B2.4	K10B2.4	n/a	chrII 6,360,595	contains similarity to Pfam domain PF03669 Uncharacterised protein family (UPF0139) contains similarity to Interpro domain IPR005351 (Protein of unknown function UPF0139)
30	F25G6.8	F25G6.8	n/a	chrV 8,564,846	contains similarity to Pfam domain PF02290 Signal recognition particle 14kD protein contains similarity to Interpro domains IPR009018 (Signal recognition particle, SRP9/SRP14 subunit), IPR003210 (Signal recognition particle, SRP14 subunit)
31	npp-2	T01G9.4	n/a	chrI 8,292,456	npp-2 encodes a protein with low similarity to rat nucleoporin Nup75 that affects embryonic viability and has a variety of other defects in RNAi screens including: nuclear morphology, growth, fertility, locomotion, and egg laying; enriched in oocytes.
32	T01E8.6	T01E8.6	n/a	chrII 10,241,373	contains similarity to Pfam domain PF00253 Ribosomal protein S14p/S29e contains similarity to Interpro domain IPR001209 (Ribosomal protein S14)
33	cyp-13A11	F14F7.2	n/a	chrIII 13,022,359	C. elegans CYP-13A11 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002402 (Cytochrome P450, E-class, group II), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
34	W02B12.11	W02B12.11	n/a	chrII 11,474,835	contains similarity to Pfam domain PF02709 Galactosyltransferase contains similarity to Interpro domain IPR003859 (Metazoa galactosyltransferase)
35	spt-5	K08E4.1	n/a	chrIV 12,053,606	C. elegans SPT-5 protein; contains similarity to Pfam domains PF03439 (Supt5 repeat) (2), PF00467 (KOW motif) contains similarity to Interpro domains IPR005100 (Supt5 repeat), IPR008991 (Translation protein SH3-like), IPR003257 (Transcription antitermination protein, NusG, archaea), IPR005824 (KOW), IPR017071 (Transcription elongation factor Spt5), IPR006645 (Transcription antitermination protein, NusG, N-terminal)
36	pfd-3	T06G6.9	n/a	chrI 12,729,010	pfd-3 encodes a putative prefoldin, orthologous to human VBP1 (OMIM:300133), that is required for normal alpha-tubulin synthesis, microtubule growth, mitotic spindle formation and positioning, early embryonic cell division, and embryonic and larval viability; PFD-3 is expressed cytoplasmically in most, if not all, tissues.
37	npp-11	F53F10.5	n/a	chrI 3,819,703	C. elegans NPP-11 protein; contains similarity to Interpro domains IPR003072 (Orphan nuclear receptor, NOR1 type), IPR000104 (Antifreeze protein, type I), IPR001778 (Pollen allergen Poa pIX/Phl pVI, C-terminal), IPR007758 (Nucleoporin, Nsp1-like, C-terminal)
38	C23G10.8	C23G10.8	n/a	chrIII 6,204,357	contains similarity to Homo sapiens Conserved hypothetical protein; VG:OTTHUMP00000076919
39	R74.7	R74.7	n/a	chrIII 4,205,094	contains similarity to Pfam domain PF01728 FtsJ-like methyltransferase contains similarity to Interpro domains IPR015507 (Ribosomal RNA methyltransferase J), IPR002877 (Ribosomal RNA methyltransferase RrmJ/FtsJ)
40	M03C11.8	M03C11.8	n/a	chrIII 10,432,042	contains similarity to Pfam domains PF00271 (Helicase conserved C-terminal domain) , PF00176 (SNF2 family N-terminal domain) contains similarity to Interpro domains IPR002048 (Calcium-binding EF-hand), IPR000330 (SNF2-related), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
41	vha-2	R10E11.2	n/a	chrIII 9,782,355	vha-2 and vha-3 encode an ortholog of subunit c of the membrane-bound (V0) domain of vacuolar proton-translocating ATPase (V-ATPase); the protein encoded by vha-2 and vha-3 (VHA-2/3) is identical; VHA-2/3 is a predicted V-ATPase transmembrane rotor component, whose polypeptide sequence is identical to that of VHA-3; VHA-1 and VHA-2/3 comprise a closely related family of subunit c co-orthologs, predicted to carry protons from the cytosol to a-subunits (VHA-5, VHA-6, VHA-7, or UNC-32) for transmembrane export; VHA-2/3 is dispensable for viability, since vha-2/3(RNAi) animals have mostly healthy progeny; however, VHA-2 is required for ovulation and embryogenesis, since vha-2(RNAi) animals are sterile with polyploid, unmatured oocytes; VHA-2, along with VHA-15 and probably all V-ATPase subunits, is required for systemic RNAi, probably during endocytotic RNAi uptake; VHA-2 is required for necrosis, since vha-2(RNAi) suppresses necrotic neurodegeneration; vha-2 shares an operon with vha-1 and R10E11.6; both vha-2 and vha-1 are expressed in the excretory cell, the rectum, and a pair of cells posterior to the anus.
42	B0303.2	B0303.2	n/a	chrIII 8,685,551	contains similarity to Pfam domain PF01234 NNMT/PNMT/TEMT family contains similarity to Interpro domain IPR000940 (Methyltransferase, NNMT/PNMT/TEMT)
43	C47C12.4	C47C12.4	n/a	chrX 7,757,369	contains similarity to Pfam domains PF08355 (EF hand associated) , PF00071 (Ras family) , PF00036 (EF hand) , PF08477 (Miro-like protein) contains similarity to Interpro domains IPR013566 (EF hand associated, type-1), IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand), IPR003577 (Ras small GTPase, Ras type), IPR013684 (Miro-like), IPR003578 (Ras small GTPase, Rho type), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR013753 (Ras)
44	B0464.2	B0464.2	n/a	chrIII 9,494,244	contains similarity to Pfam domains PF07719 (Tetratricopeptide repeat) (3), PF00515 (Tetratricopeptide repeat) (8)contains similarity to Interpro domains IPR001440 (Tetratricopeptide TPR-1), IPR011990 (Tetratricopeptide-like helical), IPR013105 (Tetratricopeptide TPR2), IPR013026 (Tetratricopeptide region), IPR008940 (Protein prenyltransferase)
45	tsfm-1	F55C5.5	n/a	chrV 12,270,895	F55C5.5 encodes a translational elongation factor Ts (EF-Ts) that binds two different EF-Tu proteins (EF-TU1/Y71H2AM.23 and EF-TU2/C43E11.4) in vitro, stimulating guanine-nucleotide exchange and mRNA translation; F55C5.5 is predicted to be mitochondrial and has a putative N-terminal transit peptide sequence; F55C5.5 is required in mass RNAi assays for normally rapid growth and for maintenance of the germline.
46	K10D11.6	K10D11.6	n/a	chrIV 12,988,061	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domain IPR003366 (CUB-like region)
47	Y32B12B.2	Y32B12B.2	n/a	chrV 16,544,097	contains similarity to Vitis vinifera Putative uncharacterized protein.; TR:A5AD22
48	C07D8.6	C07D8.6	n/a	chrX 7,342,092	contains similarity to Pfam domain PF00248 Aldo/keto reductase family contains similarity to Interpro domain IPR001395 (Aldo/keto reductase)
49	C06A8.3	C06A8.3	n/a	chrII 7,790,994	contains similarity to Pfam domain PF02520 Domain of unknown function DUF148 contains similarity to Interpro domain IPR003677 (Protein of unknown function DUF148)
50	F28H6.4	F28H6.4	n/a	chrX 14,130,605	contains similarity to Pfam domain PF04435 Domain of unknown function (DUF545) contains similarity to Interpro domains IPR006570 (SPK), IPR012287 (Homeodomain-related), IPR009057 (Homeodomain-like)