UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	K10D11.5	K10D11.5	0	chrIV 12,990,724	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domains IPR000859 (CUB), IPR003006 (Immunoglobulin/major histocompatibility complex, conserved site), IPR003366 (CUB-like region)
2	srv-29	T13A10.6	n/a	chrIV 6,265,730	C. elegans SRV-29 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
3	T10E10.4	T10E10.4	n/a	chrX 6,318,637	T10E10.4 encodes a large (966-residue) protein, predicted to be secreted, with two N-terminal chitin-binding peritrophin-A domains followed by 14 cysteine-rich domains and one C-terminal EB module; the general organization of T10E10.4 protein resembles that of K04H4.2; T10E10.4 has no obvious function in mass RNAi assays but, like CEJ-1 and CPG-2, might participate in chitin synthesis.
4	F25C8.4	F25C8.4	n/a	chrV 20,901,062	contains similarity to Pfam domain PF00501 AMP-binding enzyme contains similarity to Interpro domain IPR000873 (AMP-dependent synthetase and ligase)
5	W04E12.7	W04E12.7	n/a	chrV 19,731,742	contains similarity to Pfam domain PF06162 Caenorhabditis elegans protein of unknown function (DUF976) contains similarity to Interpro domains IPR010381 (Protein of unknown function DUF976, Caenorhabditis species), IPR016125 (Peptidase C15, pyroglutamyl peptidase I-like)
6	C32D5.6	C32D5.6	n/a	chrII 6,332,890	contains similarity to Interpro domain IPR013026 (Tetratricopeptide region)
7	T07G12.2	T07G12.2	n/a	chrIV 10,531,796	contains similarity to Pfam domain PF00860 Permease family contains similarity to Interpro domain IPR006043 (Xanthine/uracil/vitamin C permease)
8	ZK488.6	ZK488.6	n/a	chrV 591,473	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
9	H02F09.3	H02F09.3	n/a	chrX 1,570,762	contains similarity to Interpro domain IPR001757 (ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)
10	B0554.2	B0554.2	n/a	chrV 435,748	contains similarity to Pfam domain PF02795 Domain of unknown function (DUF225) contains similarity to Interpro domain IPR004024 (Protein of unknown function DUF225)
11	ugt-25	C10H11.3	n/a	chrI 4,733,442	C. elegans UGT-25 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
12	F10D11.4	F10D11.4	n/a	chrI 8,441,960	contains similarity to Interpro domain IPR005819 (Histone H5)
13	srxa-2	F56D5.10	n/a	chrIV 9,423,882	C. elegans SRXA-2 protein; contains similarity to Pfam domain PF03383 Caenorhabditis serpentine receptor-like protein, class xa contains similarity to Interpro domain IPR005047 (Protein of unknown function DUF286, G protein-coupled receptor-like putative Caenorhabditis species)
14	odd-1	B0280.4	n/a	chrIII 7,108,745	odd-1 encodes a C2H2-type zinc finger-containing transcription factor similar to Drosophila odd skipped which is required for embryonic patterning; ODD-1 is expressed in the gut during embryogenesis and appears to be essential for larval development.
15	F40A3.2	F40A3.2	n/a	chrV 7,880,134	contains similarity to Interpro domains IPR000742 (EGF-like, type 3), IPR013032 (EGF-like region, conserved site)
16	F42C5.4	F42C5.4	n/a	chrIV 7,290,079	contains similarity to Interpro domain IPR001841 (Zinc finger, RING-type)
17	K04F10.1	K04F10.1	n/a	chrI 6,365,571	The K04F10.1 gene encodes a homolog of SCA1, which when mutated leads to spinocerebellar ataxia 1 (OMIM:164400).
18	F40A3.7	F40A3.7	n/a	chrV 7,897,725	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
19	C26E1.2	C26E1.2	n/a	chrV 13,306,168	contains similarity to Interpro domain IPR000169 (Eukaryotic thiol (cysteine) protease)
20	ZK899.3	ZK899.3	n/a	chrX 9,454,242	contains similarity to Homo sapiens C10ORF6; ENSEMBL:ENSP00000238961
21	F55A4.4	F55A4.4	n/a	chrX 1,025,409	contains similarity to Pfam domain PF00035 Double-stranded RNA binding motif contains similarity to Interpro domains IPR001159 (Double-stranded RNA binding), IPR014720 (Double-stranded RNA-binding-like)
22	hmit-1.2	Y51A2D.5	n/a	chrV 18,526,923	hmit-1.2 encodes one of three C. elegans proton (H+)-dependent myo-inositol transporters; loss of hmit-1.2 activity via large-scale RNAi result in no obvious abnormalities but by homology, HMIT-1.2 is predicted to function as a plasma membrane protein required for the regulated uptake of myo-inositol and thus potentially for regulation of cell signaling and intracellular osmolarity.
23	wrt-8	C29F3.2	n/a	chrV 15,343,304	wrt-8 encodes a hedgehog-like protein, with (from N- to C-terminus) a signal sequence, a Wart domain, an short region of low-complexity sequence, and a Hint/Hog domain; WRT-8 is strongly expressed in hypodermal syncytia hyp6-hyp10 throughout life, and in in 12 subventral P cells and their descendants from 3-fold embryo to L2 larva stages; the Hint/Hog domain is predicted to cut WRT-8 into two halves and then covalently link cholesterol to the C-terminus of the Wart domain; the Wart domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; WRT-8 has no obvious function in RNAi assays.
24	F59E11.6	F59E11.6	n/a	chrV 8,992,414	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domain IPR002542 (Protein of unknown function DUF19)
25	srx-64	K07C6.7	n/a	chrV 3,930,085	C. elegans SRX-64 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
26	ZK1320.9	ZK1320.9	n/a	chrII 9,685,397	contains similarity to Pfam domain PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain contains similarity to Interpro domains IPR003702 (Acetyl-CoA hydrolase/transferase), IPR001220 (Legume lectin, beta domain)
27	C40H5.3	C40H5.3	n/a	chrX 11,760,088	contains similarity to Solanum aggregatum NADH dehydrogenase subunit (Fragment).; TR:Q8HSG2
28	C30F12.5	C30F12.5	n/a	chrI 6,995,898	contains similarity to Interpro domain IPR000694 (Proline-rich region)
29	W02B12.9	W02B12.9	n/a	chrII 11,470,937	contains similarity to Pfam domain PF00153 Mitochondrial carrier protein contains similarity to Interpro domains IPR002067 (Mitochondrial carrier protein), IPR001993 (Mitochondrial substrate carrier), IPR002113 (Adenine nucleotide translocator 1)
30	T21C9.6	T21C9.6	n/a	chrV 10,584,474	contains similarity to Pfam domains PF00391 (PEP-utilising enzyme, mobile domain) , PF01326 (Pyruvate phosphate dikinase, PEP/pyruvate binding domain) contains similarity to Interpro domains IPR008279 (PEP-utilising enzyme, mobile region), IPR013815 (ATP-grasp fold, subdomain 1), IPR002192 (Pyruvate phosphate dikinase, PEP/pyruvate-binding), IPR013816 (ATP-grasp fold, subdomain 2)
31	T20H9.6	T20H9.6	n/a	chrIII 2,247,987	contains similarity to Pfam domain PF02206 Domain of unknown function contains similarity to Interpro domain IPR003125 (Protein of unknown function WSN)
32	F56A12.2	F56A12.2	n/a	chrV 14,377,560	contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
33	C54C8.2	C54C8.2	n/a	chrI 12,445,611	contains similarity to Homo sapiens N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase; ENSEMBL:ENSP00000309096
34	F41G3.3	F41G3.3	n/a	chrII 6,757,638
35	srj-39	F38H12.1	n/a	chrV 4,105,406	C. elegans SRJ-39 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
36	plc-2	Y75B12B.6	n/a	chrV 15,195,140	C. elegans PLC-2 protein; contains similarity to Pfam domains PF00387 (Phosphatidylinositol-specific phospholipase C, Y domain) , PF00388 (Phosphatidylinositol-specific phospholipase C, X domain) contains similarity to Interpro domains IPR001192 (Phospholipase C, phosphoinositol-specific, C-terminal (PLC)), IPR000909 (Phospholipase C, phosphatidylinositol-specific , X region), IPR001711 (Phospholipase C, phosphatidylinositol-specific, Y domain), IPR013841 (Phospholipase C, phosphatidylinositol-specific , X and Y boxes)
37	W04C9.2	W04C9.2	n/a	chrI 489,263
38	C08F11.7	C08F11.7	n/a	chrIV 13,637,874	contains similarity to Pfam domain PF04435 Domain of unknown function (DUF545) contains similarity to Interpro domains IPR006570 (SPK), IPR002398 (Peptidase C14, caspase precursor p45)
39	C32E8.1	C32E8.1	n/a	chrI 3,796,427	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
40	gpdh-1	F47G4.3	n/a	chrI 14,077,014	gpdh-1 encodes one of two C. elegans glycerol 3-phosphate dehydrogenases; although loss of gpdh-1 activity via large-scale RNAi screens results in no obvious defects, gpdh-1 mRNA expression is upregulated in response to hypertonicity, suggesting that GPDH-1 does play a role in osmotic stress adaptation in C. elegans.
41	H06O01.2	H06O01.2	n/a	chrI 7,012,174	H06O01.2 encodes a large (1,461-aa) putative chromodomain helicase DNA-binding protein that inhibits DHC-1 in vivo; H06O01.2 is orthologous to budding yeast CHD1, human CHD1 (OMIM:602118), and human CHD2 (OMIM:602119); H06O01.2(RNAi) suppresses the lethality of conditional dhc-1 mutations, as well as the spindle length and cytokinesis defects of dhc-1(or195), indicating that H06O01.2 negatively regulates dynein; H06O01.2 has no obvious function in mass RNAi assays.
42	F55A12.6	F55A12.6	n/a	chrI 5,340,452	contains similarity to Interpro domain IPR002952 (Eggshell protein)
43	C30B5.6	C30B5.6	n/a	chrII 6,220,573
44	ZK673.1	ZK673.1	n/a	chrII 10,444,162	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domains IPR000104 (Antifreeze protein, type I), IPR001778 (Pollen allergen Poa pIX/Phl pVI, C-terminal), IPR003582 (Metridin-like ShK toxin)
45	T10D4.1	T10D4.1	n/a	chrII 3,151,352	contains similarity to Pfam domains PF01579 (Domain of unknown function DUF19) , PF02343 (Domain of unknown function DUF130) contains similarity to Interpro domains IPR003326 (Protein of unknown function DUF130), IPR002542 (Protein of unknown function DUF19)
46	F35C8.2	F35C8.2	n/a	chrX 5,375,578	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
47	C42C1.6	C42C1.6	n/a	chrIV 12,294,581	contains similarity to Drosophila melanogaster Flybase gene name is CG16970-PA; FLYBASE:CG16970-PA
48	F53C11.3	F53C11.3	n/a	chrV 13,783,418	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR000507 (Adrenergic receptor, beta 1), IPR002424 (Insect alcohol dehydrogenase family), IPR003560 (2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
49	lin-48	F34D10.5	n/a	chrIII 3,746,355	lin-48 encodes a C2H2-type zinc-finger transcription factor that is orthologous to Drosophila OVO and mouse OVO1; LIN-48 is required for development of the hindgut, the male tail, and the excretory duct cell; in hindgut and male tail development, LIN-48 activity is essential for proper fate specification of the U, F, and K' blast cells and B blast cell descendants, and in excretory duct cell development, for normal duct cell morphogenesis; a LIN-48 translational reporter is expressed in the nuclei of the U, F, K, and K' blast cells, the excretory duct cell, and up to 10 cells in the head region beginning in late embryogenesis and continuing through adulthood; in addition, expression is detected in the neuronal support cells of the phasmid and labial sensory structures beginning at the late L1 larval stage; in hindgut cell specification, LIN-48 functions with EGL-38/Pax, which appears to be a direct transcriptional regulator of LIN-48 expression, and in excretory duct cell development, LIN-48 is likely under the control of the CES-2 bZip transcription factor
50	nhr-247	ZK1037.5	n/a	chrV 15,324,578	C. elegans NHR-247 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)