UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	K09H11.7	K09H11.7	0	chrV 5,752,981	contains similarity to Pfam domain PF00702 haloacid dehalogenase-like hydrolase contains similarity to Interpro domains IPR006357 (HAD-superfamily hydrolase, subfamily IIA), IPR006349 (2-phosphoglycolate phosphatase, eukaryotic), IPR005834 (Haloacid dehalogenase-like hydrolase)
2	col-104	F58F6.1	n/a	chrIV 1,354,497	C. elegans COL-104 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (3)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR001150 (Formate C-acetyltransferase glycine radical), IPR008160 (Collagen triple helix repeat)
3	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
4	his-33	F17E9.13	n/a	chrIV 8,335,508	his-33 encodes an H2A histone; by homology, HIS-33 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-33 is a replication-dependent histone locus that resides in the HIS5 cluster on chromosome IV.
5	cnx-1	ZK632.6	n/a	chrIII 9,815,658	cnx-1 encodes the C. elegans ortholog of calnexin, a type I Ca2+-binding integral membrane protein of the endoplasmic reticulum (ER); CNX-1 binds calcium and is predicted to function as a molecular chaperone required for glycoprotein folding and maturation as well as regulation of intracellular calcium homeostasis; in C. elegans, cnx-1 activity is required at 25 degrees C for wild-type levels of fertility and normal embryonic and larval development; cnx-1 activity is also required for maintaining viability in response to ER stress; in addition, cnx-1(RNAi) can suppress necrotic-like cell death induced by hyperactivated MEC-4 and DEG-1 ion channels, suggesting that CNX-1 also plays a role in regulating necrotic cell death; CNX-1 expression is first detected ubiquitously in the early embryo, with expression then becoming restricted to embryonic head and tail regions; post-embryonic expression is seen in the excretory cell, head and tail neurons, spermatheca, intestine, germ cells, and spicules in the male tail; antibody staining of early embryos indicates that CNX-1 localizes to the endoplasmic reticulum; in regulating reproduction at 25 degrees C, cnx-1 functions redundantly with crt-1, which encodes calreticulin, an additional Ca2+-binding ER chaperone protein.
6	his-61	F55G1.10	n/a	chrIV 7,485,966	his-61 encodes an H2A histone.
7	C53A3.2	C53A3.2	0	chrV 5,763,175	contains similarity to Pfam domain PF00702 haloacid dehalogenase-like hydrolase contains similarity to Interpro domains IPR006357 (HAD-superfamily hydrolase, subfamily IIA), IPR006349 (2-phosphoglycolate phosphatase, eukaryotic), IPR005834 (Haloacid dehalogenase-like hydrolase)
8	amx-3	F25C8.2	n/a	chrV 20,896,026	C. elegans AMX-3 protein; contains similarity to Pfam domain PF01593 Flavin containing amine oxidoreductase contains similarity to Interpro domains IPR000759 (Adrenodoxin reductase), IPR001613 (Flavin-containing amine oxidase), IPR002937 (Amine oxidase), IPR016040 (NAD(P)-binding)
9	let-711	F57B9.2	n/a	chrIII 6,952,757	let-711 encodes the C. elegans ortholog of NOT1, the conserved core component of the multisubunit CCR4/NOT complex that plays a role in regulation of gene expression via various processes including transcriptional control, mRNA deadenylation, and protein ubiquitination; in C. elegans, let-711 activity is essential for embryonic and larval development and in particular, for proper spindle positioning, microtubule length, and centrosome morphology in early embryos; in addition, let-711 is essential for normal germline development and levels of fertility; in embryos, let-711 mutations can suppress the short microtubule phenotype produced by mutations in zyg-9, which encodes the C. elegans XMAP125 homolog, and centrosomoal ZYG-9 levels are increased in let-711 mutants, suggesting that let-711 functions, in part, by negatively regulating ZYG-9 levels or localization; in situ hybridization studies indicate that let-711 mRNA is broadly expressed in the gonad and that its gonadal expression is negatively regulated by lin-35/Rb.
10	T06D8.10	T06D8.10	n/a	chrII 11,244,135	contains similarity to Pfam domain PF03098 Animal haem peroxidase contains similarity to Interpro domains IPR010255 (Haem peroxidase), IPR002007 (Haem peroxidase, animal), IPR001007 (von Willebrand factor, type C)
11	drr-1	F45H10.4	n/a	chrII 13,495,384	C. elegans DRR-1 protein; contains similarity to Interpro domain IPR008253 (Marvel)
12	C42D4.2	C42D4.2	n/a	chrIV 7,181,781	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domain IPR002018 (Carboxylesterase, type B)
13	his-43	F08G2.2	n/a	chrII 13,827,426	his-43 encodes an H2A histone.
14	F23H11.3	F23H11.3	n/a	chrIII 900,827	contains similarity to Pfam domains PF00549 (CoA-ligase) , PF02629 (CoA binding domain) contains similarity to Interpro domains IPR005811 (ATP-citrate lyase/succinyl-CoA ligase), IPR005810 (Succinyl-CoA ligase, alpha subunit), IPR016040 (NAD(P)-binding), IPR017440 (ATP-citrate lyase/succinyl-CoA ligase, active site), IPR003781 (CoA-binding), IPR016102 (Succinyl-CoA synthetase-like)
15	T17H7.7	T17H7.7	n/a	chrIII 756,721
16	F44E7.2	F44E7.2	0	chrV 5,771,094	contains similarity to Pfam domain PF00702 haloacid dehalogenase-like hydrolase contains similarity to Interpro domains IPR006357 (HAD-superfamily hydrolase, subfamily IIA), IPR006349 (2-phosphoglycolate phosphatase, eukaryotic), IPR005834 (Haloacid dehalogenase-like hydrolase)
17	C05D12.2	C05D12.2	n/a	chrII 11,420,763	contains similarity to Interpro domains IPR000742 (EGF-like, type 3), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR013032 (EGF-like region, conserved site), IPR006582 (Region of unknown fuction MD, Caenorhabditis elegans)
18	his-7	F45F2.4	n/a	chrV 8,533,548	his-7 encodes an H2A histone.
19	T24C12.4	T24C12.4	n/a	chrX 2,204,550
20	T07C4.10	T07C4.10	n/a	chrIII 10,323,248	contains similarity to Interpro domains IPR002957 (Keratin, type I), IPR000533 (Tropomyosin), IPR009053 (Prefoldin)
21	B0393.5	B0393.5	n/a	chrIII 4,772,641	contains similarity to Pfam domains PF00008 (EGF-like domain) (2), PF07645 (Calcium binding EGF domain) (6), PF06119 (Nidogen-like) (2)contains similarity to Interpro domains IPR003886 (Nidogen, extracellular region), IPR001438 (EGF-like, type 2), IPR001881 (EGF-like calcium-binding), IPR000742 (EGF-like, type 3), IPR013032 (EGF-like region, conserved site), IPR006209 (EGF-like), IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR013091 (EGF calcium-binding), IPR006210 (EGF)
22	F22G12.4	F22G12.4	n/a	chrI 13,157,287	contains similarity to Pfam domains PF01363 (FYVE zinc finger) , PF00023 (Ankyrin repeat) (17)contains similarity to Interpro domains IPR000306 (Zinc finger, FYVE-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR002110 (Ankyrin), IPR017455 (Zinc finger, FYVE-related), IPR011011 (Zinc finger, FYVE/PHD-type)
23	F32G8.2	F32G8.2	n/a	chrV 10,552,095	contains similarity to Pfam domain PF02995 Protein of unknown function (DUF229) contains similarity to Interpro domain IPR004245 (Protein of unknown function DUF229)
24	lact-8	Y42A5A.2	n/a	chrV 11,092,342	lact-8 encodes a beta-lactamase domain-containing protein that contains a predicted transmembrane domain in its N terminus.
25	sec-15	C28G1.3	n/a	chrX 8,833,671	C. elegans SEC-15 protein; contains similarity to Pfam domain PF04091 Exocyst complex subunit Sec15-like contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR007225 (Exocyst complex subunit Sec15-like)
26	grd-6	T18H9.1	n/a	chrV 9,223,090	grd-6 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central low-complexity proline-rich domain, and a C-terminal Ground domain; GRD-6 is expressed in hypodermis and in various neurons, in both head and tail, and the PVT interneuron; the Ground domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; GRD-6 has no obvious function in RNAi assays.
27	his-66	H02I12.6	n/a	chrIV 11,400,571	his-66 encodes an H2B histone.
28	F02D8.4	F02D8.4	n/a	chrV 14,986,177	contains similarity to Pfam domain PF00246 Zinc carboxypeptidase contains similarity to Interpro domains IPR000834 (Peptidase M14, carboxypeptidase A), IPR009020 (Proteinase inhibitor, propeptide)
29	pod-1	Y76A2B.1	n/a	chrIII 13,519,397	The pod-1 gene encodes a coronin-like protein required for asymmetry along the anterior-posterior axis at the beginning of embryonic development.
30	K09H11.1	K09H11.1	n/a	chrV 5,749,898	contains similarity to Pfam domains PF08028 (Acyl-CoA dehydrogenase, C-terminal domain) , PF01636 (Phosphotransferase enzyme family) , PF02770 (Acyl-CoA dehydrogenase, middle domain) , PF00441 (Acyl-CoA dehydrogenase, C-terminal domain) , PF00702 (haloacid dehalogenase-like hydrolase) contains similarity to Interpro domains IPR011945 (Predicted HAD-superfamily phosphatase, subfamily IA/Epoxide hydrolase, N-terminal), IPR005833 (Haloacid dehydrogenase/epoxide hydrolase), IPR013107 (Acyl-CoA dehydrogenase, type 2, C-terminal), IPR006090 (Acyl-CoA oxidase/dehydrogenase, type 1), IPR013786 (Acyl-CoA dehydrogenase/oxidase, N-terminal), IPR006091 (Acyl-CoA dehydrogenase/oxidase, central region), IPR011009 (Protein kinase-like), IPR006402 (HAD-superfamily hydrolase, subfamily IA, variant 3), IPR013764 (Acyl-CoA oxidase/dehydrogenase, type1/2, C-terminal), IPR009100 (Acyl-CoA dehydrogenase/oxidase, middle and N-terminal), IPR000169 (Peptidase, cysteine peptidase active site), IPR005834 (Haloacid dehalogenase-like hydrolase), IPR008266 (Tyrosine protein kinase, active site), IPR002575 (Aminoglycoside phosphotransferase)
31	pxn-1	ZK994.3	n/a	chrV 8,498,505	C. elegans PXN-1 protein; contains similarity to Pfam domains PF07686 (Immunoglobulin V-set domain) , PF00047 (Immunoglobulin domain) (2), PF00560 (Leucine Rich Repeat) (4), PF01462 (Leucine rich repeat N-terminal domain) , PF07679 (Immunoglobulin I-set domain) (2), PF03098 (Animal haem peroxidase) contains similarity to Interpro domains IPR003598 (Immunoglobulin subtype 2), IPR000483 (Cysteine-rich flanking region, C-terminal), IPR001611 (Leucine-rich repeat), IPR013098 (Immunoglobulin I-set), IPR010255 (Haem peroxidase), IPR003596 (Immunoglobulin V-set, subgroup), IPR013783 (Immunoglobulin-like fold), IPR003591 (Leucine-rich repeat, typical subtype), IPR013106 (Immunoglobulin V-set), IPR007110 (Immunoglobulin-like), IPR002007 (Haem peroxidase, animal), IPR000372 (Leucine-rich repeat, cysteine-rich flanking region, N-terminal), IPR003599 (Immunoglobulin subtype), IPR013151 (Immunoglobulin)
32	nas-38	F57C12.1	n/a	chrX 560,901	C. elegans NAS-38 protein; contains similarity to Pfam domains PF00431 (CUB domain) , PF00090 (Thrombospondin type 1 domain) , PF01400 (Astacin (Peptidase family M12A)) contains similarity to Interpro domains IPR000884 (Thrombospondin, type I), IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR001506 (Peptidase M12A, astacin), IPR006026 (Peptidase, metallopeptidases), IPR000859 (CUB), IPR013032 (EGF-like region, conserved site)
33	F07A11.5	F07A11.5	n/a	chrII 11,613,153	contains similarity to Pfam domain PF00294 pfkB family carbohydrate kinase contains similarity to Interpro domains IPR011611 (Carbohydrate/purine kinase), IPR011877 (Ribokinase, bacterial), IPR002139 (Ribokinase)
34	C24B5.4	C24B5.4	n/a	chrV 9,196,537	contains similarity to Pfam domain PF08925 Domain of Unknown Function (DUF1907) contains similarity to Interpro domain IPR015021 (Region of unknown function DUF1907)
35	T05C12.4	T05C12.4	n/a	chrII 8,178,909	contains similarity to Interpro domain IPR003566 (T-cell surface glycoprotein CD5)
36	T24D1.2	T24D1.2	n/a	chrI 9,954,687	contains similarity to Interpro domain IPR001841 (Zinc finger, RING-type)
37	ugt-14	H23N18.2	n/a	chrV 4,907,256	C. elegans UGT-14 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
38	T06E4.8	T06E4.8	n/a	chrV 9,622,529	contains similarity to Interpro domain IPR000694 (Proline-rich region)
39	C46H3.1	C46H3.1	n/a	chrX 1,210,043
40	T15D6.11	T15D6.11	n/a	chrI 12,397,457	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
41	his-57	F54E12.5	n/a	chrIV 11,340,574	his-57 encodes an H2A histone.
42	M05B5.4	M05B5.4	n/a	chrI 7,189,526	The M05B5.4 gene encodes an ortholog of the human gene LECITHIN-CHOLESTEROL ACYLTRANSFERASE (LCAT; OMIM:606967), which when mutated leads to lecithin-cholesterol acyltransferase deficiency (OMIM:245900).
43	M195.2	M195.2	n/a	chrII 8,362,076	contains similarity to Pfam domain PF02363 Cysteine rich repeat
44	F56D1.2	F56D1.2	n/a	chrII 5,476,416	contains similarity to Pfam domain PF08357 SEFIR domain contains similarity to Interpro domain IPR013568 (SEFIR)
45	K09F6.2	K09F6.2	n/a	chrII 2,268,709	contains similarity to Pfam domain PF06869 Protein of unknown function (DUF1258) contains similarity to Interpro domain IPR009667 (Protein of unknown function DUF1258)
46	R09D1.12	R09D1.12	n/a	chrII 9,451,202	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR008266 (Tyrosine protein kinase, active site)
47	F56A12.2	F56A12.2	n/a	chrV 14,377,560	contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
48	W06A11.2	W06A11.2	n/a	chrII 4,060,321
49	pmp-4	T02D1.5	n/a	chrIV 17,404,001	The pmp-4 gene encodes a homolog of human ALD, which when mutated leads to X-linked adrenoleukodystrophy (OMIM:300100).
50	F26E4.6	F26E4.6	n/a	chrI 9,773,519	contains similarity to Pfam domain PF02935 Cytochrome c oxidase subunit VIIc contains similarity to Interpro domain IPR004202 (Cytochrome c oxidase subunit VIIc)