UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	K09F6.2	K09F6.2	0	chrII 2,268,709	contains similarity to Pfam domain PF06869 Protein of unknown function (DUF1258) contains similarity to Interpro domain IPR009667 (Protein of unknown function DUF1258)
2	W06A11.2	W06A11.2	n/a	chrII 4,060,321
3	math-24	C46F9.3	n/a	chrII 1,901,084	The C46F9.3 gene encodes a protein with a meprin-associated Traf homology (MATH) domain that may be involved in apoptosis.
4	F32G8.2	F32G8.2	n/a	chrV 10,552,095	contains similarity to Pfam domain PF02995 Protein of unknown function (DUF229) contains similarity to Interpro domain IPR004245 (Protein of unknown function DUF229)
5	R05H11.1	R05H11.1	n/a	chrIII 6,796,617	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
6	F55A12.5	F55A12.5	n/a	chrI 5,347,791	contains similarity to Gallus gallus Nucleolin (Protein C23).; SW:P15771
7	rhr-2	B0240.1	n/a	chrV 11,729,008	rhr-2 encodes a predicted transmembrane protein with similarity to human Rh blood group antigens proposed to function in inorganic ion transport and metabolism; the role of RHR-2 in C. elegans development or behavior remains unclear, as loss of RHR-2 function via RNA-mediated interference does not result in any abnormalities.
8	str-25	F44G3.11	n/a	chrV 16,116,262	C. elegans STR-25 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
9	let-711	F57B9.2	n/a	chrIII 6,952,757	let-711 encodes the C. elegans ortholog of NOT1, the conserved core component of the multisubunit CCR4/NOT complex that plays a role in regulation of gene expression via various processes including transcriptional control, mRNA deadenylation, and protein ubiquitination; in C. elegans, let-711 activity is essential for embryonic and larval development and in particular, for proper spindle positioning, microtubule length, and centrosome morphology in early embryos; in addition, let-711 is essential for normal germline development and levels of fertility; in embryos, let-711 mutations can suppress the short microtubule phenotype produced by mutations in zyg-9, which encodes the C. elegans XMAP125 homolog, and centrosomoal ZYG-9 levels are increased in let-711 mutants, suggesting that let-711 functions, in part, by negatively regulating ZYG-9 levels or localization; in situ hybridization studies indicate that let-711 mRNA is broadly expressed in the gonad and that its gonadal expression is negatively regulated by lin-35/Rb.
10	T24A6.1	T24A6.1	n/a	chrV 3,559,431
11	T24D1.2	T24D1.2	n/a	chrI 9,954,687	contains similarity to Interpro domain IPR001841 (Zinc finger, RING-type)
12	T15D6.11	T15D6.11	n/a	chrI 12,397,457	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
13	his-66	H02I12.6	n/a	chrIV 11,400,571	his-66 encodes an H2B histone.
14	C47G2.4	C47G2.4	n/a	chrII 11,292,129	contains similarity to Pfam domain PF04791 LMBR1-like membrane protein contains similarity to Interpro domain IPR006876 (LMBR1-like conserved region)
15	M18.3	M18.3	n/a	chrIV 12,107,094	contains similarity to Pfam domain PF00733 Asparagine synthase contains similarity to Interpro domains IPR001962 (Asparagine synthase), IPR014729 (Rossmann-like alpha/beta/alpha sandwich fold)
16	K09F6.5	K09F6.5	n/a	chrII 2,272,724	contains similarity to Interpro domain IPR000358 (Ribonucleotide reductase)
17	str-245	F32A7.7	n/a	chrI 14,853,699	C. elegans STR-245 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR001991 (Sodium:dicarboxylate symporter)
18	nph-1	M28.7	n/a	chrII 10,650,519	nph-1 encodes a novel, SH3 domain-containing protein that is orthologous to mammalian nephrocystin-1.
19	nspb-3	F38A5.5	n/a	chrIV 6,594,788	C. elegans NSPB-3 protein; contains similarity to Pfam domain PF07312 Protein of unknown function (DUF1459) contains similarity to Interpro domain IPR009924 (Protein of unknown function DUF1459)
20	M02D8.2	M02D8.2	n/a	chrX 8,739,895
21	R52.2	R52.2	n/a	chrII 2,127,157	contains similarity to Pfam domains PF03564 (Protein of unknown function (DUF1759)) , PF05585 (Protein of unknown function (DUF1758)) contains similarity to Interpro domains IPR009007 (Peptidase aspartic, catalytic), IPR008737 (Protein of unknown function DUF1758), IPR005312 (Protein of unknown function DUF1759), IPR001878 (Zinc finger, CCHC-type)
22	ZK1128.1	ZK1128.1	n/a	chrIII 10,113,863	contains similarity to Pfam domain PF02636 Uncharacterized ACR, COG1565 contains similarity to Interpro domain IPR003788 (Protein of unknown function DUF185)
23	cul-4	F45E12.3	n/a	chrII 7,303,864	cul-4 encodes one of six C. elegans cullin proteins; CUL-4 activity is essential for negative regulation of DNA-replication licensing and thus, for maintenance of genome stability; in regulating DNA replication, CUL-4 functions as part of a CUL-4/DDB-1 ubiquitin ligase complex that degrades the replication licensing factor CDT-1 and indirectly promotes nuclear export of the replication licensing factor CDC-6 by negatively regulating the levels of the CKI-1 CDK inhibitor; cul-4 mRNA is expressed throughout development with highest levels seen in embryos and lower levels seen in larvae and adults; maternal cul-4 mRNA is present in early embryos and larval and adult mRNA is most notably present in the intestine and germ line.
24	C33H5.7	C33H5.7	n/a	chrIV 7,775,184	contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
25	ZC84.6	ZC84.6	n/a	chrIII 9,196,038	contains similarity to Pfam domains PF01683 (EB module) (3), PF00014 (Kunitz/Bovine pancreatic trypsin inhibitor domain) (5)contains similarity to Interpro domains IPR002223 (Proteinase inhibitor I2, Kunitz metazoa), IPR006150 (Cysteine-rich repeat), IPR006149 (Nematode-specific EB region)
26	ZK1193.3	ZK1193.3	n/a	chrX 418,922	contains similarity to Interpro domains IPR000742 (EGF-like, type 3), IPR013032 (EGF-like region, conserved site)
27	C14C6.3	C14C6.3	n/a	chrV 544,415
28	C05D12.2	C05D12.2	n/a	chrII 11,420,763	contains similarity to Interpro domains IPR000742 (EGF-like, type 3), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR013032 (EGF-like region, conserved site), IPR006582 (Region of unknown fuction MD, Caenorhabditis elegans)
29	T05D4.3	T05D4.3	n/a	chrIII 13,568,545	contains similarity to Interpro domain IPR005838 (Type III secretion system inner membrane P protein)
30	srt-17	F48G7.6	n/a	chrV 624,474	C. elegans SRT-17 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
31	T05E11.6	T05E11.6	n/a	chrIV 11,109,297	contains similarity to Pfam domain PF01650 Peptidase C13 family contains similarity to Interpro domain IPR001096 (Peptidase C13, legumain)
32	F36H2.2	F36H2.2	n/a	chrI 9,247,697	contains similarity to Pfam domain PF01733 Nucleoside transporter contains similarity to Interpro domains IPR002259 (Delayed-early response protein/equilibrative nucleoside transporter), IPR016196 (MFS general substrate transporter)
33	C49A9.3	C49A9.3	n/a	chrIV 6,223,512	contains similarity to Pfam domain PF03312 Protein of unknown function, DUF272 contains similarity to Interpro domains IPR000711 (ATPase, F1 complex, OSCP/delta subunit), IPR004987 (Protein of unknown function DUF272)
34	srx-108	F40H7.2	n/a	chrII 3,706,336	C. elegans SRX-108 protein ;
35	M88.4	M88.4	n/a	chrIII 4,550,251	contains similarity to Interpro domains IPR011993 (Pleckstrin homology-type), IPR006020 (Phosphotyrosine interaction region)
36	C04F5.8	C04F5.8	n/a	chrV 5,112,623	contains similarity to Bos taurus Similar to C04F5.8.; TR:Q0IIF4
37	pes-8	F18G5.2	n/a	chrX 9,254,218	pes-8 encodes a novel protein that contains a proline-rich region and a predicted transmembrane domain, but no otherwise recognizably conserved domains; pes-8 was identified in promoter trapping screens and based on large-scale RNA-mediated interference (RNAi) screens, appears to be required for egg laying, germline development, locomotion, and regulation of adult lifespan; a pes-8 reporter is expressed at the cell surfaces of the spermathecal valve cell, the uterine wall, the vulva, and the rectal epithelium; strong expression is also detected in the uterus during its development; PES-8 may be required for normal morphology of the openings of the spermathecal valve, the vulva, and the rectum, a hypothesis consistent with its expression pattern and RNAi phenotype.
38	C18B10.6	C18B10.6	n/a	chrV 7,480,150	contains similarity to Pfam domains PF02958 (Domain of unknown function (DUF227)) , PF07914 (Protein of unknown function (DUF1679)) contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species), IPR004119 (Protein of unknown function DUF227), IPR015897 (CHK kinase-like)
39	fbxa-139	B0391.9	n/a	chrV 15,593,604	C. elegans FBXA-139 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
40	B0285.4	B0285.4	n/a	chrIII 4,344,312	contains similarity to Pfam domain PF04072 Leucine carboxyl methyltransferase contains similarity to Interpro domains IPR016651 (Leucine carboxyl methyltransferase, LCTM1 1), IPR007213 (Leucine carboxyl methyltransferase)
41	srw-127	C33G8.1	n/a	chrV 7,013,646	C. elegans SRW-127 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
42	nol-1	W07E6.1	n/a	chrII 473,591	C. elegans NOL-1 protein; contains similarity to Pfam domain PF01189 NOL1/NOP2/sun family contains similarity to Interpro domains IPR011023 (Nop2p), IPR006174 (rRNA subunit methyltransferase), IPR001678 (Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p)
43	R186.3	R186.3	n/a	chrV 12,966,597	contains similarity to Interpro domains IPR006687 (GTP-binding protein SAR1), IPR005225 (Small GTP-binding protein), IPR001806 (Ras GTPase), IPR006688 (ADP-ribosylation factor), IPR003593 (AAA+ ATPase, core)
44	fbxa-114	Y113G7B.7	n/a	chrV 20,197,592	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
45	ptr-11	F56C11.2	n/a	chrI 163,495	ptr-11 encodes a nematode-specific member of the sterol sensing domain (SSD) proteins, distantly paralogous to Drosophila PATCHED (PTC) and human PTCH (OMIM:601309, mutated in basal cell nevus syndrome); PTR-11 is required for normal growth to full size, locomotion, and vulval morphogenesis.
46	F19C7.3	F19C7.3	n/a	chrIV 4,598,308	contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
47	F01G4.4	F01G4.4	n/a	chrIV 11,144,606	contains similarity to Myxococcus xanthus Pseudouridine synthase (EC 5.4.99.-).; TR:Q1D5Q2
48	set-14	R06F6.4	n/a	chrII 10,794,856	set-14 encodes a divergent ortholog of human SMYD1 (OMIM:606846), SMYD2 (OMIM:610663), and SYMD3 (OMIM:608783); SET-14 is paralogous to SET-10, SET-18, and SET-30; SET-14 has no obvious function in individual RNAi assays of vulval development, or in mass RNAi assays.
49	fbxb-119	B0462.3	n/a	chrV 18,319,134	C. elegans FBXB-119 protein; contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
50	F56F10.4	F56F10.4	n/a	chrX 867,910	contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR000664 (Lethal(2) giant larvae protein)