UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	K09E9.3	K09E9.3	0	chrX 15,612,740	contains similarity to Interpro domain IPR000533 (Tropomyosin)
2	sra-25	T26E3.9	n/a	chrI 12,687,150	C. elegans SRA-25 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domains IPR003945 (NADH-plastoquinone oxidoreductase, chain 5), IPR000344 (Nematode chemoreceptor, Sra)
3	egl-18	F55A8.1	n/a	chrIV 1,915,415	egl-18 encodes a member of the GATA-family of transcription factors that affects cell migration, cell fate specification; expressed in the head, in hypodermal seam cells, VC neurons, and vulval precursor cells.
4	F19D8.2	F19D8.2	n/a	chrX 13,835,397	contains similarity to Homo sapiens Splice isoform 1 of Q9UMN6 Myeloid/lymphoid or mixed-lineage leukemia protein 4; ENSEMBL:ENSP00000222270
5	Y9D1A.2	Y9D1A.2	n/a	chrII 7,450,882	contains similarity to Homo sapiens Uncharacterized protein ENSP00000370861; ENSEMBL:ENSP00000370861
6	cec-1	ZK1236.2	n/a	chrIII 8,427,378	cec-1 encodes a nuclear protein with a chromodomain that is ubiquitously expressed in somatic cells, but is dispensable for embryonic survival or gross adult morphology.
7	crn-5	C14A4.5	n/a	chrII 10,593,065	C. elegans CRN-5 protein; contains similarity to Pfam domain PF01138 3' exoribonuclease family, domain 1 contains similarity to Interpro domain IPR001247 (Exoribonuclease, phosphorolytic domain 1)
8	lsm-4	F32A5.7	n/a	chrII 7,252,636	C. elegans LSM-4 protein; contains similarity to Pfam domain PF01423 LSM domain contains similarity to Interpro domains IPR001163 (Like-Sm ribonucleoprotein, core), IPR006649 (Like-Sm ribonucleoprotein, eukaryotic and archaea-type, core), IPR010920 (Like-Sm ribonucleoprotein-related, core)
9	T19H12.6	T19H12.6	n/a	chrV 4,877,093	contains similarity to Pfam domains PF04942 (CC domain) (2), PF01019 (Gamma-glutamyltranspeptidase) contains similarity to Interpro domains IPR007026 (Domian of unknown function, DUF-CC), IPR000101 (Gamma-glutamyltranspeptidase)
10	B0304.2	B0304.2	n/a	chrII 4,524,073
11	ZK1098.3	ZK1098.3	n/a	chrIII 9,535,467	contains similarity to Pfam domain PF01612 3'-5' exonuclease contains similarity to Interpro domains IPR002562 (3'-5' exonuclease), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
12	sop-2	C50E10.4	n/a	chrII 12,342,269	sop-2 encodes a SAM domain-containing protein that is related to, but not orthologous with, Polycomb group proteins and ETS transcription factors; during development, SOP-2 activity is required for maintaining a restricted pattern of Hox gene expression, such as that of mab-5 and egl-5, to specific cells and tissues; thus, SOP-2 is required for proper cell fate specification in a variety of cell lineages, including the serotonergic and dopaminergic male tail neurons and the ventral nerve cord; in regulating neurotransmitter phenotype, sop-2 functions together with sor-3, which also encodes a Polycomb group protein, and members of the TGF-beta signaling pathway; sop-2 and sor-3 also function together to regulate progression through larval development; a SOP-2::GFP reporter fusion is expressed in the nuclei of all somatic cells beginning at the 50-cell stage of embryogenesis; SOP-2::GFP expression is initially diffuse, but by the 200-cell stage is visible in distinct nuclear bodies, the size and number of which may correlate with DNA content.
13	K01A2.3	K01A2.3	n/a	chrII 315,416
14	atg-10	D2085.2	n/a	chrII 8,659,384	C. elegans ATG-10 protein; contains similarity to Pfam domain PF03987 Autophagocytosis associated protein, C-terminal domain contains similarity to Interpro domain IPR007135 (Autophagocytosis associated protein, C-terminal)
15	adr-2	T20H4.4	n/a	chrIII 7,231,956	adr-2 encodes an adenosine deaminase that acts on RNA (ADAR); ADARs are RNA-editing enzymes that deaminate adenosines to create inosines in double-stranded RNA (dsRNA); adr-2 is expressed ubiquitously in early embryos, as well as in the germline of early adults; ADR-2 is required for ADAR activity in vivo, and for normal chemotaxis.
16	ZK418.5	ZK418.5	n/a	chrIII 7,073,217	contains similarity to Mus musculus Transmembrane protein 147.; SW:Q9CQG6
17	T05G5.4	T05G5.4	n/a	chrIII 9,749,322	contains similarity to Homo sapiens Trichohyalin; ENSEMBL:ENSP00000290632
18	C28H8.1	C28H8.1	n/a	chrIII 5,926,486	C28H8.1 is orthologous to the human gene BCL7A (OMIM:601406), which when mutated leads to high-grade B-cell non-Hodgkin lymphoma.
19	T23F11.4	T23F11.4	n/a	chrIII 4,664,270	contains similarity to Interpro domain IPR007087 (Zinc finger, C2H2-type)
20	W02D7.6	W02D7.6	n/a	chrV 8,300,526	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
21	F26F12.4	F26F12.4	n/a	chrV 5,867,027
22	fbxb-105	F08D12.8	n/a	chrII 2,770,341	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
23	dnj-23	T24H10.3	n/a	chrII 9,107,885	This gene encodes a protein containing a DnaJ ('J') domain.
24	T10B5.3	T10B5.3	n/a	chrV 1,866,374	contains similarity to Pfam domain PF08162 NUC189 domain contains similarity to Interpro domain IPR012979 (Protein of unknown function NUC189, C-terminal)
25	sdz-21	F54E7.5	n/a	chrIII 5,655,941	C. elegans SDZ-21 protein; contains similarity to Interpro domain IPR000480 (Glutelin)
26	R07E5.3	R07E5.3	n/a	chrIII 4,405,506	The R07E5.3 gene encodes a homolog of SNF5/Ini1, a component of the SWI/SNF complex that is conserved from yeast to mammals and that is involved in chromatin remodeling; R07E5.3 may be involved in asymmetric cell division of the T cells.
27	C05G5.3	C05G5.3	n/a	chrX 14,751,355	contains similarity to Homo sapiens Isoform 1 of Matrix-remodeling-associated protein 7; ENSEMBL:ENSP00000348050
28	T01D1.4	T01D1.4	n/a	chrII 178,045	contains similarity to Pfam domain PF03079 ARD/ARD' family contains similarity to Interpro domains IPR011051 (Cupin, RmlC-type), IPR004313 (Acireductone dioxygenase, ARD), IPR014710 (RmlC-like jelly roll fold)
29	hlh-19	F57C12.3	n/a	chrX 556,516	C. elegans HLH-19 protein; contains similarity to Pfam domain PF00010 Helix-loop-helix DNA-binding domain contains similarity to Interpro domains IPR001092 (Basic helix-loop-helix dimerisation region bHLH), IPR011598 (Helix-loop-helix DNA-binding)
30	EGAP2.1	EGAP2.1	n/a	chrII 5,232,292
31	fbxa-104	T06E6.13	n/a	chrV 15,422,084	C. elegans FBXA-104 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
32	smo-1	K12C11.2	n/a	chrI 1,340,894	C. elegans SMO-1 protein; contains similarity to Pfam domain PF00240 Ubiquitin family contains similarity to Interpro domain IPR000626 (Ubiquitin)
33	tag-170	C05D11.3	n/a	chrIII 6,432,606	C05D11.3/tag-170 encodes a thioredoxin domain-containing protein orthologous to human TXNDC9 and ENSG00000145268; in one-cell embryos, C05D11.3/TAG-170 is required for normal nuclear-centrosome rotation, male pronuclear migration, cytokinesis, and mitotic spindles, and for normally long astral microtubules; in early embryos, C05D11.3/TAG-170 is also required for normally rapid microtubule elongation; C05D11.3/tag-170 is expressed in larval and adult neurons and pharynx, and in vulva, with its strongest transcription in adults; like its mammalian ortholog, C05D11.3/TAG-170 protein is both nuclear and cytoplasmic.
34	R166.3	R166.3	n/a	chrII 10,538,486	The R166.3 gene encodes an unfamiliar protein, with homologs in yeast and archaea, that is orthologous to the human gene ALPORT SYNDROME, MENTAL RETARDATION, MIDFACE HYPOPLASIA, AND ELLIPTOCYTOSIS CHROMOSOMAL REGION GENE 1 (AMMECR1; OMIM:300195); AMMECR1, when mutated, may be at least partially responsible for mental retardation, midface hypoplasia, or elliptocytosis.
35	cal-3	M02B7.6	n/a	chrIV 3,832,350	cal-3 encodes a member of the calmodulin family.
36	VH15N14R.1	VH15N14R.1	n/a	chrI 7,781,895	contains similarity to Aspergillus niger Protein kinase C-like (EC 2.7.1.-).; SW:KPC1_ASPNG
37	mau-2	C09H6.3	n/a	chrI 8,127,936	mau-2 encodes an ortholog of budding yeast Scc4p, Drosophila CG4203, and human KIAA0892; MAU-2 is required (with PQN-85 and SCC-3) for normal mitotic chromosome segregation, and for cellular (e.g., neuronal) or axonal migration; MAU-2 is required for migration both embryonically and postembryonically, along both dorsoventral and longitudinal body axes; MAU-2 guides the axonal projection of AVM (and probably other neurons) by some cell-autonomous mechanism independent of SLT-1; MAU-2 is also required for normal larval development, locomotion, excretory canals and osmoregulation, phasmid morphology, and egg-laying; the primary sequences of MAU-2 and its Scc4-like orthologs are composed of tetratricopeptide repeats, and are highly divergent between yeast and metazoa; MAU-2 is expressed ubiquitously in embryos during late gastrulation, subsequently becoming restricted to neurons; mau-2 transcripts are abundant in oocytes, and maternal transcripts alone can support normal MAU-2 protein synthesis through the L3 larval stage (but not in L4 larvae or adults); MAU-2's N-terminal 371 residues of MAU-2 are its most conserved domain, and are sufficient to transgenically rescue mau-2 mutants; despite its behavioral phenotype, MAU-2 is thought to act early in development, since the uncoordinated phenotype of mau-2 mutants is maternal; while the uncoordinated phenotype of mau-2 mutants can be rescued either maternally or zygotically, the egg-laying phenotype of mau-2 mutants is purely zygotic; partially penetrant mau-2 dye-filling phenotypes occur on one side of the body, suggesting that MAU-2 acts on a whole side of an embryo at a time; while mau-2(RNAi) has no obvious early embryonic phenotype, joint mau-2/scc-3(RNAi) grossly deranges chromosomal segregation in early embryos, and mau-2(RNAi) enhances the lagging of anaphase chromosomes induced by pqn-85(RNAi).
38	R10E4.11	R10E4.11	n/a	chrIII 4,299,234	contains similarity to Pfam domain PF00096 (Zinc finger, C2H2 type)
39	T05C1.3	T05C1.3	n/a	chrII 4,488,577
40	H43I07.2	H43I07.2	n/a	chrV 4,201,565	contains similarity to Pfam domains PF01000 (RNA polymerase Rpb3/RpoA insert domain) , PF01193 (RNA polymerase Rpb3/Rpb11 dimerisation domain) contains similarity to Interpro domains IPR011263 (DNA-directed RNA polymerase, RpoA/D/Rpb3-type), IPR011262 (DNA-directed RNA polymerase, insert), IPR011261 (DNA-directed RNA polymerase, dimerisation)
41	exos-1	Y48A6B.5	n/a	chrIII 11,009,701	C. elegans EXOS-1 protein ; contains similarity to Drosophila melanogaster Flybase gene name is Csl4-PA;; FLYBASE:CG6249
42	gpc-2	F08B6.2	n/a	chrI 6,757,967	gpc-2 encodes one of two C. elegans heterotrimeric G protein gamma subunits; gpc-2 is required, along with its partner GPB-1, a G protein beta subunit, for proper mitotic spindle positioning and orientation during early embryonic cell divisions; to date, GPC-2 expression has been reported in electrically excitable cells (all neurons and muscles).
43	F37B4.10	F37B4.10	n/a	chrV 2,876,718	contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
44	dnj-14	K02G10.8	n/a	chrX 4,710,717	This gene encodes a protein containing a DnaJ ('J') domain.
45	hda-3	R06C1.1	n/a	chrI 11,915,408	hda-3 encodes a member of the histone deacetylase family most similar to human histone deacetylase 1 (HD1) that affects radiation sensitivity.
46	R09F10.3	R09F10.3	n/a	chrX 8,295,584	contains similarity to Dictyostelium discoideum Spore coat protein sp96.; SW:P14328
47	B0207.8	B0207.8	n/a	chrI 5,951,441
48	bath-39	F25H9.4	n/a	chrV 13,460,604	C. elegans BATH-39 protein; contains similarity to Pfam domains PF00651 (BTB/POZ domain) , PF00917 (MATH domain) contains similarity to Interpro domains IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
49	hmg-4	T20B12.8	n/a	chrIII 7,380,295	hmg-4 encodes a protein with strong similarity to the highly conserved high mobility group protein SSRP1 (structure-specific DNA recognition protein); by homology, HMG-4 is predicted to be a member of the FACT (facilitates chromatin transcription) complex that functions as a transcription elongation factor; RNAi experiments indicate that hmg-4 is required for locomotion and larval development, and required redundantly with hmg-3, its paralog, for embryonic development.
50	btb-13	ZC204.11	n/a	chrII 1,654,256	C. elegans BTB-13 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000209 (Peptidase S8 and S53, subtilisin, kexin, sedolisin), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)