UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	K09E3.6	K09E3.6	2e-179	chrX 17,114,487	contains similarity to Pfam domain PF03353 DUF278 contains similarity to Interpro domain IPR005020 (Protein of unknown function DUF278)
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	C26B9.6	C26B9.6	n/a	chrX 5,334,221	contains similarity to Pfam domains PF00097 (Zinc finger, C3HC4 type (RING finger)) , PF02825 (WWE domain) (2)contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR004170 (WWE), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
4	K03A11.1	K03A11.1	n/a	chrX 13,053,489	contains similarity to Interpro domain IPR001130 (Deoxyribonuclease, TatD-related)
5	F28C6.1	F28C6.1	n/a	chrII 8,591,963	F28C6.1 encodes an AP-2-like transcription factor that is ~60% identical to that of F28C6.2 which lies immediately adjacent to F28C6.1 on chromosome II; loss of F28C6.1 activity via large-scale RNAi experiments results in embryonic and larval lethality.
6	ZK563.5	ZK563.5	n/a	chrX 3,378,206	contains similarity to Aedes aegypti Putative uncharacterized protein.; TR:Q17A46
7	F56B3.9	F56B3.9	n/a	chrIV 772,200
8	F52D10.2	F52D10.2	n/a	chrX 11,590,643	contains similarity to Interpro domains IPR011993 (Pleckstrin homology-type), IPR006020 (Phosphotyrosine interaction region)
9	gly-17	T15D6.3	n/a	chrI 12,377,779	gly-17 encodes a protein similar to 2/I N-acetylglucosaminyltransferase.
10	nhr-273	T12C9.1	n/a	chrII 4,436,140	C. elegans NHR-273 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
11	efn-4	F56A11.3	n/a	chrIV 563,657	efn-4 encodes a member of the ephrin family of ligands that affects neuroblast migrations during closure of the ventral gastrulation cleft and subsequent epidermal morphogenesis, possibly functioning independently of EFN-1, EFN-2, EFN-3, and the VAB-1 receptor during morphogenesis; can interact with VAB-1 in vitro, and is expressed in neural and epidermal precursors at the 100-cell stage, in head neurons, pharyngeal cells, lateral and tail neurons, and in the ectoderm during epidermal enclosure.
12	T21C9.1	T21C9.1	n/a	chrV 10,577,614	contains similarity to Pfam domain PF00595 PDZ domain (Also known as DHR or GLGF) contains similarity to Interpro domain IPR001478 (PDZ/DHR/GLGF)
13	E01G6.3	E01G6.3	n/a	chrX 12,243,099	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domains IPR002018 (Carboxylesterase, type B), IPR016196 (MFS general substrate transporter)
14	str-125	T05E12.1	n/a	chrV 17,075,114	C. elegans STR-125 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
15	T24E12.1	T24E12.1	n/a	chrII 3,786,852	contains similarity to Interpro domain IPR009071 (High mobility group box, HMG)
16	T05B4.8	T05B4.8	n/a	chrV 4,115,949	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
17	F31D5.1	F31D5.1	n/a	chrII 4,220,835	contains similarity to Pfam domain PF05978 Eukaryotic protein of unknown function (DUF895) contains similarity to Interpro domains IPR010291 (Protein of unknown function DUF895, eukaryotic), IPR003976 (Potassium channel, two pore-domain, TREK), IPR016196 (MFS general substrate transporter)
18	F36F12.4	F36F12.4	n/a	chrV 2,089,002	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
19	B0281.8	B0281.8	n/a	chrII 2,312,169	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR000315 (Zinc finger, B-box), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
20	C01G12.5	C01G12.5	n/a	chrII 14,586,920	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR002424 (Insect alcohol dehydrogenase family), IPR003560 (2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
21	fbxb-117	F55C9.1	n/a	chrV 19,283,568	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
22	C27F2.5	C27F2.5	n/a	chrIII 4,961,124	C27F2.5 encodes the C. elegans ortholog of the conserved vacuolar protein sorting protein EAP30/SNF8/VPS22; by homology, the product of C27F2.5 is predicted to be a component of an ESCRT-II complex (Endosomal Sorting Complex Required for Transport) that functions in endosomal transport.
23	R01B10.2	R01B10.2	n/a	chrV 6,042,173
24	ZK637.2	ZK637.2	n/a	chrIII 8,888,857	contains similarity to Pfam domain PF05811 Eukaryotic protein of unknown function (DUF842) contains similarity to Interpro domain IPR008560 (Protein of unknown function DUF842, eukaryotic)
25	bath-36	Y75B12B.4	n/a	chrV 15,189,546	C. elegans BATH-36 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
26	F45G2.7	F45G2.7	n/a	chrIII 13,433,876	contains similarity to Oceanobacillus iheyensis Two-component response regulator involved in modulation ofsflagellar.; TR:Q8EQW9
27	mop-25.2	Y53C12A.4	n/a	chrII 9,702,750	mop-25.2 encodes a Mo25 protein that inhibits DHC-1 in vivo; MOP-25.2 is orthologous to fission yeast Mo25p, budding yeast Hym1p, Aspergillus nidulans HymA, human CAB39, and human CAB39L; MOP-25.2 is paralogous to MOP-25.1 and (more distantly) MOP-25.3; mop-25.2(RNAi) suppresses the lethality of conditional dhc-1 mutations, as well as the spindle length and cytokinesis defects of dhc-1(or195), indicating that MOP-25.2 negatively regulates dynein; in early embryos, MOP-25.2 is associated with the midbody and spindle poles after cytokinesis; MOP-25.2 shares a redundant function with MOP-25.1 in fertility and embryonic viability; in mass RNAi assays, MOP-25.2 is required for normal locomotion, body coloration, speed, and body size.
28	srh-206	Y102A5C.15	n/a	chrV 16,954,279	C. elegans SRH-206 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
29	srd-19	F53F1.11	n/a	chrV 13,428,164	C. elegans SRD-19 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000276 (GPCR, rhodopsin-like)
30	tag-143	ZK856.9	n/a	chrV 10,211,282	C. elegans TAG-143 protein; contains similarity to Pfam domain PF04438 HIT zinc finger contains similarity to Interpro domain IPR007529 (Zinc finger, HIT-type)
31	M01E5.1	M01E5.1	n/a	chrI 13,275,251	contains similarity to Ichthyophthirius multifiliis Immobilization antigen isoform.; TR:Q9BMH3
32	C53D6.4	C53D6.4	n/a	chrIV 9,020,038	contains similarity to Pfam domain PF00085 Thioredoxin contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR013766 (Thioredoxin domain)
33	phat-1	C46H11.8	n/a	chrI 5,045,010	C. elegans PHAT-1 protein; contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
34	egl-2	F16B3.1	n/a	chrV 1,294,353	egl-2 encodes a voltage-gated potassium channel that affects egg laying, muscle activation, defecation, mechanosensation, and chemosensation; expressed in the intestinal muscle, AFD, ALN, AQR, ASE, AWC, BAG, IL2, PLN, PQR, and URX neurons as well as a subset of sensory neurons in the male tail.
35	C46A5.8	C46A5.8	n/a	chrIV 7,769,193
36	F44C8.7	F44C8.7	n/a	chrV 2,216,907	contains similarity to Pfam domain PF04142 Nucleotide-sugar transporter contains similarity to Interpro domains IPR004689 (UDP-galactose transporter), IPR007271 (Nucleotide-sugar transporter)
37	C14C6.3	C14C6.3	n/a	chrV 544,415
38	C24H12.2	C24H12.2	n/a	chrII 437,796
39	F26F4.6	F26F4.6	n/a	chrIII 4,892,477	contains similarity to Homo sapiens Similar to Suppressor protein SRP40; VG:OTTHUMP00000170311
40	nhr-231	Y17D7B.1	n/a	chrV 18,792,886	C. elegans NHR-231 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
41	nas-12	C24F3.3	n/a	chrIV 10,225,155	nas-12 encodes an astacin-like metalloprotease; large-scale expression studies reveal that a nas-12::GFP promoter fusion is expressed in the intestine and in the pharyngeal and rectal gland cells.
42	str-1	C42D4.5	n/a	chrIV 7,174,381	C. elegans STR-1 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
43	R10H10.6	R10H10.6	n/a	chrIV 10,409,131	contains similarity to Pfam domain PF01687 Riboflavin kinase contains similarity to Interpro domain IPR015865 (Riboflavin kinase)
44	hst-2	C34F6.4	n/a	chrX 11,205,546	hst-2 encodes the C. elegans ortholog of the heparan sulfate modifying enzyme 2O-sulfotransferase; by homology, HST-2 is predicted to function in heparan sulfate biosynthesis by catalyzing the chain-modifying sulfation of the C2 hydroxyl group of hexuronic acid; during development, hst-2 activity is required for normal body size, cell migration, and nervous system development; an hst-2::gfp reporter fusion is first expressed in embryos, continuing on through adulthood; expression is detected in many tissues, including the pharynx, hypodermis, muscles, vulva, and distal tip cells (DTCs) of the somatic gonad.
45	T15B7.12	T15B7.12	n/a	chrV 6,818,884	contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
46	F23D12.2	F23D12.2	n/a	chrX 14,418,796	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
47	ins-34	F52B11.6	n/a	chrIV 14,107,090	ins-34 encodes an insulin-like peptide.
48	prx-14	R07H5.1	n/a	chrIV 11,183,588	C. elegans PRX-14 protein; contains similarity to Pfam domain PF04695 Peroxisomal membrane anchor protein (Pex14p) conserved region contains similarity to Interpro domain IPR006785 (Peroxisome membrane anchor protein Pex14p, N-terminal)
49	srbc-63	T06E6.11	n/a	chrV 15,412,055	C. elegans SRBC-63 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
50	ubc-16	Y54E5B.4	n/a	chrI 14,822,998	C. elegans UBC-16 protein; contains similarity to Pfam domain PF00179 Ubiquitin-conjugating enzyme contains similarity to Interpro domains IPR000608 (Ubiquitin-conjugating enzyme, E2), IPR016135 (Ubiquitin-conjugating enzyme/RWD-like)