UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	K09C4.6	K09C4.6	1e-116	chrX 3,275,175
2	hlh-8	C02B8.4	n/a	chrX 8,118,315	The hlh-8 gene encodes a helix-loop-helix protein required for normal muscle development, and hence for normal defecation and egg-laying.
3	T05B4.13	T05B4.13	n/a	chrV 4,126,750	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
4	K09F5.4	K09F5.4	n/a	chrX 7,710,385
5	D1005.6	D1005.6	n/a	chrX 1,463,763
6	math-9	C16C4.14	n/a	chrII 1,890,347	C. elegans MATH-9 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
7	srv-9	F53F1.8	n/a	chrV 13,422,059	C. elegans SRV-9 protein ;
8	T10G3.4	T10G3.4	n/a	chrV 13,483,233	contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
9	C25A1.5	C25A1.5	n/a	chrI 10,178,041	contains similarity to Pfam domains PF04116 (Fatty acid hydroxylase superfamily) , PF00173 (Cytochrome b5-like Heme/Steroid binding domain) contains similarity to Interpro domains IPR006694 (Fatty acid hydroxylase), IPR001199 (Cytochrome b5)
10	str-37	C50B6.12	n/a	chrV 13,328,296	C. elegans STR-37 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
11	Y49F6C.8	Y49F6C.8	n/a	chrII 3,369,682
12	Y38H6C.14	Y38H6C.14	n/a	chrV 20,527,484	contains similarity to Leishmania major strain Friedlin Proteophosphoglycan 5.; TR:Q4FX62
13	brc-2	T07E3.5	n/a	chrIII 6,901,783	brc-2 encodes a BRC domain-containing protein that is homologous to human BRCA2 which when mutated leads to early-onset breast cancer 2 or hereditary male breast cancer (OMIM:600185); in C. elegans, BRC-2 activity is essential for RAD-51-mediated repair of meiotic and radiation-induced double-strand breaks (DSBs); BRC-2 physically interacts with RAD-51 and single-stranded DNA and is required for proper localization of RAD-51 to sites of DNA damage and stabilization of RAD-51-DNA filaments; BRC-2 can also promote RAD-51-independent DSB repair via single-strand annealing (SSA) when the homologous recombination (HR) and nonhomologous end joining pathways (NHEJ) are compromised; in nonirradiated animals, BRC-2 is seen at diffuse, low levels in germline nuclei, but upon radiation treatment BRC-2 localizes to discrete foci that coincide with presumptive sites of DNA damage.
14	F58F6.3	F58F6.3	n/a	chrIV 1,375,965
15	F26F2.3	F26F2.3	n/a	chrV 20,561,363	contains similarity to Saccharomyces cerevisiae Profilin synthetic lethal protein, has region of coiled-coil structure; subunit of the Exocyst complex--the Exocyst complex contains the gene products encoded by SEC3, SEC5, SEC6, SEC8, SEC10, SEC15 and EXO70 and is required for exocytosis; SGD:YER008C
16	hap-1	ZC395.7	n/a	chrIII 5,264,428	C. elegans HAP-1 protein; contains similarity to Pfam domain PF01725 Ham1 family contains similarity to Interpro domain IPR002637 (Ham1-like protein)
17	srj-55	Y45G12A.1	n/a	chrV 2,857,011	C. elegans SRJ-55 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
18	ces-1	F43G9.11	n/a	chrI 8,634,989	ces-1 encodes a C2H2-type zinc finger transcription factor that is a member of the Snail family of proteins that includes Drosophila Scratch, Snail, and Slug, and human SNAIL and SLUG; although the normal function of CES-1 is not fully understood, gain-of-function mutations indicate that CES-1 can function as a transcriptional repressor that blocks programmed cell death in specific neurons by inhibiting expression of the cell-death activator EGL-1; in regulating EGL-1 expression, CES-1 appears to antagonize the transcriptional activity of the bHLH proteins, HLH-2 and HLH-3; despite its cell-type specific role in apoptosis, CES-1 expression is reportedly detected in many embryonic nuclei from the 100-cell stage of embryogenesis through the beginning of morphogenesis, with some CES-1 expression remaining at later embryonic stages; genetic studies indicate that CES-1 is negatively regulated by the bZIP transcription factor CES-2, which can bind CES-1 upstream sequences in vitro and thus may directly regulate CES-1 transcription in vivo
19	nspc-14	F42F12.7	n/a	chrX 12,358,778	C. elegans NSPC-14 protein ;
20	R05D7.1	R05D7.1	n/a	chrI 12,162,955	contains similarity to Kluyveromyces lodderae Truncated cytochrome oxidase subunit 2 (Fragment).; TR:Q7YG01
21	F47B10.9	F47B10.9	n/a	chrX 10,913,178	contains similarity to Interpro domains IPR011333 (BTB/POZ fold), IPR013089 (Kelch related)
22	K07D4.2	K07D4.2	n/a	chrII 4,045,127
23	lis-1	T03F6.5	n/a	chrIII 13,373,822	lis-1 encodes an ortholog of human LIS1, which when mutated leads to lissencephaly (OMIM:247200); it also encodes an ortholog of the Aspergillus nidulans nudF, which mediates nuclear migration along Aspergillus hyphae.
24	Y57G11A.3	Y57G11A.3	n/a	chrIV 14,502,754	contains similarity to Pfam domain PF00412 LIM domain contains similarity to Interpro domain IPR001781 (Zinc finger, LIM-type)
25	F11C3.1	F11C3.1	n/a	chrI 14,869,588	contains similarity to Xenopus laevis ATP-dependent DNA helicase PIF1 (EC 3.6.1.-).; SW:Q0R4F1
26	srj-40	F38H12.2	n/a	chrV 4,102,865	C. elegans SRJ-40 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
27	C05A9.3	C05A9.3	n/a	chrX 10,830,625	contains similarity to Pfam domain PF00023 Ankyrin repeat contains similarity to Interpro domain IPR002110 (Ankyrin)
28	hsf-1	Y53C10A.12	n/a	chrI 11,957,869	hsf-1 encodes the C. elegans heat-shock transcription factor ortholog; HSF-1 functions as a transcriptional regulator of stress-induced gene expression whose activity is required for heat-shock and proteotoxicity response, larval development, innate immunity, and regulation of adult lifespan.
29	aqp-7	M02F4.8	n/a	chrX 3,026,113	aqp-7 encodes an aquaglyceroporin whose expression in Xenopus oocytes increases either water or glycerol permeability five- to seven-fold; AQP-7 has no function in mass RNAi assays, perhaps reflecting genetic redundancy with its several paralogs; AQP-7 is expressed in muscle punctae (perhaps focal adhesions).
30	C33E10.8	C33E10.8	n/a	chrX 17,293,743	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
31	F09G8.5	F09G8.5	n/a	chrIII 8,256,200	contains similarity to Pfam domain PF00560 Leucine Rich Repeat contains similarity to Interpro domains IPR003603 (U2A'/phosphoprotein 32 family A, C-terminal), IPR010916 (TonB box, conserved site)
32	T17A3.9	T17A3.9	n/a	chrIII 152,890
33	dos-1	ZK507.4	n/a	chrIII 9,105,304	C. elegans DOS-1 protein ;
34	fbxa-100	F14H3.7	n/a	chrV 16,060,910	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
35	ZK546.5	ZK546.5	n/a	chrII 4,936,745	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
36	C28G1.4	C28G1.4	n/a	chrX 8,851,319	contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
37	clec-168	F38A1.7	n/a	chrIV 1,258,213	C. elegans CLEC-168 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
38	C44E4.5	C44E4.5	n/a	chrI 4,607,929	contains similarity to Pfam domain PF04969 CS domain contains similarity to Interpro domains IPR008978 (HSP20-like chaperone), IPR017447 (CS), IPR007052 (CS domain)
39	dnj-24	W03A5.7	n/a	chrIII 5,417,808	This gene encodes a protein containing a DnaJ ('J') domain.
40	srj-26	ZK262.10	n/a	chrV 18,422,252	C. elegans SRJ-26 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
41	C17C3.13	C17C3.13	n/a	chrII 5,568,064
42	srt-70	B0238.6	n/a	chrV 5,258,776	C. elegans SRT-70 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
43	F29D10.2	F29D10.2	n/a	chrI 8,842,038	contains similarity to Interpro domains IPR000853 (Nematoda metallothionein, family 6), IPR000006 (Metallothionein, vertebrate), IPR002952 (Eggshell protein), IPR004035 (Endonuclease III, iron-sulphur binding, conserved site-1), IPR001396 (Echinodermata metallothionein, family 4), IPR001008 (Mollusc metallothionein, family 2)
44	F47G4.8	F47G4.8	n/a	chrI 14,053,124
45	F29C12.6	F29C12.6	n/a	chrII 13,129,953	contains similarity to Helicobacter pylori Cytotoxicity associated immunodominant antigen (120 kDa protein)s(CAG pathogenicity island protein 26).; SW:CAGA_HELPY
46	F29A7.5	F29A7.5	n/a	chrII 2,747,560
47	ccb-2	W10C8.1	n/a	chrI 2,848,257	C. elegans CCB-2 protein; contains similarity to Pfam domains PF00774 (Dihydropyridine sensitive L-type calcium channel (Beta subunit)) (2), PF00018 (SH3 domain) contains similarity to Interpro domains IPR000584 (Voltage-dependent calcium channel, L-type, beta subunit), IPR001452 (Src homology-3)
48	sru-4	C33A12.10	n/a	chrIV 9,498,965	C. elegans SRU-4 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
49	Y45G12C.6	Y45G12C.6	n/a	chrV 2,541,544	contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
50	K03D10.3	K03D10.3	n/a	chrI 14,122,952	The K03D10.3 gene encodes a MYST acetyltransferase orthologous to the Drosophila MALES-ABSENT-ON-THE-FIRST (MOF) and CG1894 proteins, the human MOF protein, and the S. cerevisiae SAS2 protein.