UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	rab-14	K09A9.2	5e-121	chrX 15,605,871	rab-14 encodes a member of the Rab GTPase family.
2	srsx-14	C39H7.5	n/a	chrIV 5,625,990	C. elegans SRSX-14 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
3	F32D1.3	F32D1.3	n/a	chrV 4,355,654	contains similarity to Pfam domains PF07719 (Tetratricopeptide repeat) (3), PF08409 (Domain of unknown function (DUF1736)) , PF00515 (Tetratricopeptide repeat) (6)contains similarity to Interpro domains IPR011990 (Tetratricopeptide-like helical), IPR013618 (Region of unknown function DUF1736), IPR008940 (Protein prenyltransferase), IPR001440 (Tetratricopeptide TPR-1), IPR013105 (Tetratricopeptide TPR2), IPR013026 (Tetratricopeptide region)
4	tkr-1	C38C10.1	n/a	chrIII 9,386,535	tkr-1 encodes a G protein-coupled receptor that is the C. elegans tachykinin-like neuropeptide receptor homolog; by homology, TKR-1 is predicted to function in modulation of excitatory neurotransmission; as loss of tkr-1 activity via RNAi results in moderate reduction of fat content, TKR-1 may play a specific role in regulating lipid metabolism; a tkr-1 reporter gene fusion is reportedly expressed in the socket cells of the deirid and post-deirid sensilla from the L2 larval stage through adulthood.
5	F02E11.2	F02E11.2	n/a	chrII 3,267,119
6	mif-3	F13G3.9	n/a	chrI 7,313,193	C. elegans MIF-3 protein; contains similarity to Pfam domain PF01187 Macrophage migration inhibitory factor (MIF) contains similarity to Interpro domains IPR014347 (Tautomerase), IPR001398 (Macrophage migration inhibitory factor)
7	R13A1.1	R13A1.1	n/a	chrIV 7,220,097
8	gcy-18	ZK896.8	n/a	chrIV 12,863,005	gcy-18 encodes a receptor-type guanylyl cyclase that, along with gcy-8 and gcy-23, constitutes a subfamily of guanylyl cyclase genes in C. elegans; gcy-18 functions redundantly with gcy-8 and gcy-23, and upstream of tax-4, to regulate thermotaxis via the AFD thermosensory neurons, although of the three guanylyl cyclases required, genetic analyses suggest that GCY-18 is the primary guanylyl cyclase required; in addition, microarray experiments indicate that gcy-18 expression is induced in daf-16(RNAi); daf-2(RNAi) double mutants and repressed in daf-2(RNAi) mutants, suggesting that GCY-18 activity may contribute to a shortened lifespan; consistent with this, loss of gcy-18 activity via RNAi does result in lifespan extension; GCY-18 is expressed exclusively in the AFD thermosensory neurons, where it localizes to sensory endings.
9	set-19	W01C8.3	n/a	chrX 5,677,695	set-19 encodes a SET domain-containing protein; SET-19 has no non-nematode orthologs, but several paralogs (SET-6, SET-13, SET-15, SET-20, SET-21, and SET-32); neither set-19(ok1813) nor set-19(RNAi) have any obvious phenotypes.
10	fbxa-129	F59A1.8	n/a	chrV 17,656,084	C. elegans FBXA-129 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
11	C04E7.1	C04E7.1	n/a	chrX 359,435
12	C38C3.7	C38C3.7	n/a	chrV 1,502,860	contains similarity to Pfam domains PF01827 (FTH domain) (2), PF00646 (F-box domain) contains similarity to Interpro domains IPR002900 (Protein of unknown function DUF38, Caenorhabditis species), IPR001810 (Cyclin-like F-box)
13	php-3	Y75B8A.1	n/a	chrIII 12,075,804	C. elegans PHP-3 protein; contains similarity to Pfam domain PF00046 Homeobox domain contains similarity to Interpro domains IPR012287 (Homeodomain-related), IPR000047 (Helix-turn-helix motif, lambda-like repressor), IPR001356 (Homeobox), IPR009057 (Homeodomain-like)
14	F31F4.11	F31F4.11	n/a	chrV 663,441	contains similarity to Pfam domains PF00788 (Ras association (RalGDS/AF-6) domain) , PF02204 (Vacuolar sorting protein 9 (VPS9) domain) contains similarity to Interpro domains IPR013995 (Vacuolar sorting protein 9, subgroup), IPR003123 (Vacuolar sorting protein 9), IPR000159 (Ras-association)
15	T20B6.1	T20B6.1	n/a	chrIII 2,898,031	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase)
16	str-143	C09H5.4	n/a	chrV 8,068,920	C. elegans STR-143 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
17	CD4.5	CD4.5	n/a	chrV 5,590,729
18	W02B8.3	W02B8.3	n/a	chrII 13,917,920	contains similarity to Pfam domain PF04870 Protein of unknown function, DUF644 contains similarity to Interpro domain IPR006954 (Protein of unknown function DUF644)
19	sng-1	T08A9.3	n/a	chrX 7,328,590	sng-1 encodes the C. elegans synaptogyrin ortholog, a vertebrate integral membrane synaptic vesicle protein; loss-of-function mutations in sng-1 result in no obvious defects in synaptogenesis or neuronal activity, suggesting that SNG-1 is likely required for more subtle neuronal functions; SNG-1::GFP reporters are expressed throughout the nervous system in neurons in the dorsal and ventral nerve cords, as well as the anterior nerve ring; SNG-1 colocalizes with the synaptic vesicle component SNT-1.
20	unc-9	R12H7.1	n/a	chrX 13,214,484	unc-9 encodes an innexin, an integral transmembrane channel protein that is a structural component of invertebrate gap junctions; UNC-9 is required for normal forward locomotion and egg-laying and also plays a role in the response to antihelminthics and volatile anesthetics; UNC-9 may form a functional pair with UNC-7, another C. elegans innexin, as mutations in unc-7 result in defects nearly identical to those in unc-9 mutant animals.
21	4R79.2	4R79.2	2e-27	chrIV 17,481,819	contains similarity to Pfam domains PF00071 (Ras family) , PF08477 (Miro-like protein) contains similarity to Interpro domains IPR006688 (ADP-ribosylation factor), IPR002041 (Ran GTPase), IPR013753 (Ras), IPR006687 (GTP-binding protein SAR1), IPR003577 (Ras small GTPase, Ras type), IPR013684 (Miro-like), IPR003578 (Ras small GTPase, Rho type), IPR001806 (Ras GTPase), IPR005225 (Small GTP-binding protein), IPR003579 (Ras small GTPase, Rab type)
22	T09B4.3	T09B4.3	n/a	chrI 6,177,087
23	F29A7.3	F29A7.3	n/a	chrII 2,753,579	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domain IPR006583 (CW)
24	srbc-10	C18B10.2	n/a	chrV 7,492,430	C. elegans SRBC-10 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
25	R05G6.1	R05G6.1	n/a	chrIV 7,539,920
26	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
27	F07C3.2	F07C3.2	n/a	chrV 9,226,731
28	T04G9.1	T04G9.1	n/a	chrX 792,247	contains similarity to Pfam domain PF02178 AT hook motif contains similarity to Interpro domains IPR000637 (HMG-I and HMG-Y, DNA-binding), IPR000694 (Proline-rich region)
29	srj-20	Y45G12C.15	n/a	chrV 2,572,367	C. elegans SRJ-20 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
30	R04A9.1	R04A9.1	n/a	chrX 405,128
31	W02B8.4	W02B8.4	n/a	chrII 13,922,543	contains similarity to Pfam domain PF04870 Protein of unknown function, DUF644 contains similarity to Interpro domain IPR006954 (Protein of unknown function DUF644)
32	srz-103	F14F8.4	n/a	chrV 16,678,452	C. elegans SRZ-103 protein; contains similarity to Interpro domain IPR001046 (Natural resistance-associated macrophage protein)
33	F33E2.6	F33E2.6	n/a	chrI 12,589,287	contains similarity to Interpro domains IPR006030 (Molluscan rhodopsin C-terminal tail), IPR000694 (Proline-rich region)
34	T27D1.3	T27D1.3	n/a	chrIII 3,684,552	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR008365 (Prostanoid receptor), IPR001991 (Sodium:dicarboxylate symporter), IPR002455 (GPCR, family 3, gamma-aminobutyric acid receptor, type B), IPR000276 (GPCR, rhodopsin-like)
35	C44B11.1	C44B11.1	n/a	chrIII 3,156,820	contains similarity to Pfam domain PF06905 Fas apoptotic inhibitory molecule (FAIM1) contains similarity to Interpro domain IPR010695 (Fas apoptotic inhibitory molecule)
36	F54C4.4	F54C4.4	n/a	chrIII 87,055
37	srh-79	C04F2.1	n/a	chrV 7,498,378	C. elegans SRH-79 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR000175 (Sodium:neurotransmitter symporter), IPR003002 (7TM chemoreceptor, subfamily 1)
38	str-13	C24B9.8	n/a	chrV 2,726,550	C. elegans STR-13 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
39	F10D11.5	F10D11.5	n/a	chrI 8,443,821	contains similarity to Interpro domain IPR001478 (PDZ/DHR/GLGF)
40	F56F11.5	F56F11.5	n/a	chrIII 2,853,197
41	ZK1290.10	ZK1290.10	n/a	chrII 7,552,859	contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR003582 (Metridin-like ShK toxin)
42	C01G5.3	C01G5.3	n/a	chrIV 6,537,601	contains similarity to Homo sapiens hypothetical protein; ENSEMBL:ENSP00000352916
43	C06C3.9	C06C3.9	n/a	chrII 9,377,271
44	ZK380.2	ZK380.2	n/a	chrX 1,633,167	contains similarity to Interpro domain IPR011072 (HR1 rho-binding repeat)
45	srz-10	ZK1037.11	n/a	chrV 15,308,296	C. elegans SRZ-10 protein ;
46	D2005.6	D2005.6	n/a	chrI 7,790,102	contains similarity to Homo sapiens Fusion protein SYT-SSX1; ENSEMBL:ENSP00000269138
47	srg-51	Y40H7A.8	n/a	chrIV 15,139,977	C. elegans SRG-51 protein ;
48	Y39E4B.13	Y39E4B.13	n/a	chrIII 13,092,265	contains similarity to Caulobacter crescentus Localization factor podJL (Polar organelle development protein)s[Contains: Localization factor podJS].; SW:PODJ_CAUCR
49	F57C12.2	F57C12.2	n/a	chrX 548,426	contains similarity to Pfam domain PF04670 Gtr1/RagA G protein conserved region contains similarity to Interpro domains IPR009053 (Prefoldin), IPR006762 (Gtr1/RagA G protein)
50	str-130	C09H5.9	n/a	chrV 8,089,962	C. elegans STR-130 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)