UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	K08H2.5	K08H2.5	0	chrX 13,241,615	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR017442 (Serine/threonine protein kinase-related)
2	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
3	ZC581.3	ZC581.3	n/a	chrI 6,653,325	contains similarity to Interpro domain IPR011046 (WD40 repeat-like)
4	F21D5.4	F21D5.4	n/a	chrIV 8,738,506	contains similarity to Pfam domain PF09091 Centromere binding protein B, DNA binding contains similarity to Interpro domains IPR006600 (Centromere protein B, helix-turn-helix), IPR012287 (Homeodomain-related), IPR009057 (Homeodomain-like), IPR015175 (Centromere protein B, DNA-binding region sub-type)
5	sri-74	F33H12.4	n/a	chrII 2,581,954	C. elegans SRI-74 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000576 (Proton/sugar symporter, LacY)
6	C54F6.5	C54F6.5	n/a	chrV 7,529,245
7	B0454.8	B0454.8	n/a	chrII 3,042,189	contains similarity to Pfam domain PF02795 Domain of unknown function (DUF225) contains similarity to Interpro domain IPR004024 (Protein of unknown function DUF225)
8	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
9	fbxa-103	F09C3.4	n/a	chrI 14,288,863	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
10	H14N18.2	H14N18.2	n/a	chrV 8,933,428
11	T16A1.2	T16A1.2	n/a	chrII 2,096,988	contains similarity to Pfam domain PF02206 Domain of unknown function contains similarity to Interpro domain IPR003125 (Protein of unknown function WSN)
12	glf-1	H04M03.4	n/a	chrIV 5,887,804	H04M03.4 encodes a UDP-galactopyranose mutase predicted to synthesize galactofuranose (Gal(f)) as a nucleotide sugar (UDP-Gal(f)); recombinant H04M03.4 has biochemical activity either in vivo (expressed in E. coli) or in vitro; orthologs of H04M03.4 are found in the urochordates Halocynthia and Ciona.
13	pin-2	F07C6.1	n/a	chrIV 12,794,963	pin-2 encodes a LIM domain-containing protein that, along with UNC-97, comprises the two C. elegans members of the PINCH family of predicted adapter proteins; based upon its similarity to Drosophila and vertebrate members of the PINCH family, PIN-2 is predicted to play a role in regulation of cell morphology, motility, and survival, but as loss of pin-2 via large-scale RNAi results in no obvious defects, the precise role of PIN-2 in C. elegans development and/or behavior is not yet known; a PIN-2::GFP fusion protein is first expressed in embryos just prior to hatching and in early larvae is seen in several neurons, including the PVT neuron, and in intestinal cells; during postembryonic development, neuronal expression continues, whereas intestinal expression gradually declines; PIN-2 localizes to the cytoplasm and to the nucleus, and in neurons, is seen in axonal processes and varicosities.
14	F41E7.1	F41E7.1	n/a	chrX 10,281,146	contains similarity to Pfam domain PF00999 Sodium/hydrogen exchanger family contains similarity to Interpro domains IPR006153 (Sodium/hydrogen exchanger), IPR001680 (WD40 repeat)
15	osm-1	T27B1.1	n/a	chrX 16,546,188	osm-1 encodes a WD- and WAA-repeat containing protein that is the C. elegans ortholog of intraflagellar transport (IFT) complex B component IFT172; OSM-1 is a presumptive cargo molecule for kinesin-II, and OSM-1 is required, along with OSM-6, for the proper assembly of the middle segments of sensory cilia; osm-1 may act in a pathway with avr-14 to affect resistance to ivermectin-induced cessation of pumping, and mutants are defective in avoidance of solutions of high osmotic strength; an OSM-1::GFP fusion protein is expressed in amphid and phasmid chemosensory neurons where it undergoes both anterograde and retrograde intraflagellar transport.
16	F10B5.2	F10B5.2	n/a	chrII 8,145,954	contains similarity to Pfam domain PF05282 AAR2 protein contains similarity to Interpro domain IPR007946 (AAR2)
17	scrt-1	C55C2.1	n/a	chrI 2,569,754	C. elegans SCRT-1 protein; contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007086 (Zinc finger, C2H2-subtype), IPR013087 (Zinc finger, C2H2-type/integrase, DNA-binding), IPR007087 (Zinc finger, C2H2-type)
18	fbxa-153	B0391.5	n/a	chrV 15,608,029	fbxa-153 encodes a protein with an N-terminal F-box domain and a C-terminal FTH domain; FBXA-153 has no obvious non-nematode orthologs; FBXA-153 shares N-terminal UNC-13 binding, and thus may share at least some functions, with ERI-1, W04D2.6, and Y55F3AM.13; FBXA-153 has no obvious function in mass RNAi assays.
19	fbxa-154	B0391.6	n/a	chrV 15,603,958	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
20	srg-68	ZC317.5	n/a	chrV 5,464,597	C. elegans SRG-68 protein ;
21	R07E3.7	R07E3.7	n/a	chrX 10,343,094	contains similarity to Borrelia burgdorferi Outer surface protein C (Fragment).; TR:Q93Q85
22	cyp-13A10	ZK1320.4	n/a	chrII 9,661,820	C. elegans CYP-13A10 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002402 (Cytochrome P450, E-class, group II)
23	R09A8.5	R09A8.5	n/a	chrX 12,639,412	contains similarity to Varroa destructor NADH dehydrogenase subunit 4L.; TR:Q8HCK4
24	unc-75	C17D12.2	n/a	chrI 11,596,943	unc-75 encodes an RNA-binding protein with two N-terminal RNA recognition motifs (RRMs), a glutamine/asparagine-rich linker domain, and a third C-terminal RRM; UNC-75 is orthologous to mammalian CELF/BrunoL proteins that control pre-mRNA splicing; unc-75 is expressed in all neurons and in neurosecretory gland cells, and is required for normal modulation of GABA- and acetylcholine-mediated neurotransmission; UNC-75 protein is found with other RRM proteins in dynamic nuclear speckles, consistent with a role in alternative mRNA splicing; unc-75 mutations can be rescued in vivo by a human unc-75 transgene, but not by exc-7 or W02D3.11, indicating that UNC-75 acts on evolutionarily conserved but highly specific pre-mRNA substrates; both UNC-75 and EXC-7 are required in parallel for normal cholinergic neurotransmission.
25	F35E8.10	F35E8.10	n/a	chrV 15,919,877	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
26	ceh-48	C17H12.9	n/a	chrIV 6,813,828	ceh-48 encodes a ONECUT class CUT homeobox protein with a single N-terminal cut domain; the cut domain may be a compact DNA-binding domain composed of alpha helices; CEH-48 is strongly affiliated with, and may be orthologous to, Drosophila ONECUT and mammalian HNF6 proteins; ceh-48 has no obvious function in mass RNAi assays.
27	T26G10.4	T26G10.4	n/a	chrIII 9,420,953	contains similarity to Forficula auricularia Reverse transcriptase (Fragment).; TR:O44323
28	W02C12.1	W02C12.1	n/a	chrIV 4,011,101	contains similarity to Pfam domains PF00008 (EGF-like domain) (10), PF07699 (GCC2 and GCC3) (4), PF07974 (EGF-like domain) (5), PF02494 (HYR domain) contains similarity to Interpro domains IPR001438 (EGF-like, type 2), IPR000742 (EGF-like, type 3), IPR013320 (Concanavalin A-like lectin/glucanase, subgroup), IPR003410 (Hyalin), IPR001791 (Laminin G), IPR001759 (Pentaxin), IPR000436 (Sushi/SCR/CCP), IPR006209 (EGF-like), IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR011641 (GCC2 and GCC3), IPR006150 (Cysteine-rich repeat), IPR001881 (EGF-like calcium-binding), IPR013032 (EGF-like region, conserved site), IPR013111 (EGF, extracellular), IPR008985 (Concanavalin A-like lectin/glucanase), IPR003645 (Follistatin-like, N-terminal)
29	K10G6.4	K10G6.4	n/a	chrII 3,973,888	contains similarity to Interpro domain IPR000533 (Tropomyosin)
30	hhat-2	Y57G11C.17	n/a	chrIV 14,827,743	C. elegans HHAT-2 protein; contains similarity to Pfam domain PF03062 MBOAT family contains similarity to Interpro domain IPR004299 (Membrane bound O-acyl transferase, MBOAT)
31	F59E10.3	F59E10.3	n/a	chrII 10,873,252	F59E10.3 encodes a zeta subunit of the coatomer (COPI) complex; in mass RNAi assays, F59E10.3 is required for embryonic, larval, and adult viability, for fertility, and for normal osmoregulation.
32	lin-32	T14F9.5	n/a	chrX 2,229,639	lin-32 encodes a basic helix-loop-helix transcription factor that is required for development of several types of neurons, including the touch receptor neurons and the male sensory ray neurons.
33	gmd-2	F56H6.5	n/a	chrI 12,293,092	gmd-2 encodes one of two C. elegans GDP-mannose dehydratases; in vitro, and when coexpressed with GER-1, GMD-2 catalyzes the formation of GDP-fucose from GDP-mannose; gmd-2 transcripts are generally present throughout larval and adult stages.
34	gcy-36	C46E1.2	n/a	chrX 15,482,280	gcy-36 encodes a predicted soluble guanylate cyclase that genetically interacts with npr-1 with respect to feeding behavior; expressed in AQR, PQR, and URX3.
35	C16C10.9	C16C10.9	n/a	chrIII 4,156,357	contains similarity to Bacillus anthracis MutS2 family protein.; TR:Q81L40
36	T21B10.3	T21B10.3	n/a	chrII 8,936,627	contains similarity to Homo sapiens Conserved hypothetical protein; VG:OTTHUMP00000076919
37	mbk-1	T04C10.1	n/a	chrX 14,822,147	mbk-1 encodes a putative dual-specificity kinase (predicted to have both serine/threonine and tyrosine substrates) that is orthologous to Drosophila MINIBRAIN and mammalian DYRK1A/MnbK and that has a glutamine/asparagine-rich domain; MBK-1 is found in most or all nuclei, is dispensable for viability, and perturbs olfaction in AWC when overexpressed.
38	F12F6.7	F12F6.7	n/a	chrIV 11,560,335	contains similarity to Pfam domain PF04042 DNA polymerase alpha/epsilon subunit B contains similarity to Interpro domain IPR007185 (DNA polymerase alpha/epsilon, subunit B)
39	F53G2.1	F53G2.1	n/a	chrII 2,492,698	contains similarity to Interpro domain IPR001611 (Leucine-rich repeat)
40	C39F7.5	C39F7.5	n/a	chrV 1,267,440	contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold)
41	pes-1	T28H11.4	n/a	chrIV 5,004,039	C. elegans PES-1 protein; contains similarity to Pfam domain PF00250 Fork head domain contains similarity to Interpro domains IPR011991 (Winged helix repressor DNA-binding), IPR001766 (Fork head transcription factor)
42	srbc-50	F54B8.8	n/a	chrV 15,824,406	C. elegans SRBC-50 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
43	F41C3.6	F41C3.6	n/a	chrII 4,735,969
44	W02A11.3	W02A11.3	n/a	chrI 12,739,603	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR008984 (SMAD/FHA domain), IPR001841 (Zinc finger, RING-type), IPR000694 (Proline-rich region), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011016 (Zinc finger, variant RING-type)
45	K11H12.3	K11H12.3	n/a	chrIV 672,557	contains similarity to Pfam domain PF03409 Protein of unknown function (DUF274) contains similarity to Interpro domain IPR005071 (Protein of unknown function DUF274)
46	F37C12.1	F37C12.1	n/a	chrIII 7,186,028	contains similarity to Pfam domain PF04502 Family of unknown function (DUF572) contains similarity to Interpro domain IPR007590 (Protein of unknown function DUF572)
47	T24H10.5	T24H10.5	n/a	chrII 9,103,999	contains similarity to Arthrobacter sp C2-2 Putative histidine kinase.; TR:Q8KRF2
48	F31D5.4	F31D5.4	n/a	chrII 4,179,466	contains similarity to Pfam domain PF01825 Latrophilin/CL-1-like GPS domain contains similarity to Interpro domain IPR000203 (GPS)
49	sup-10	R09G11.1	n/a	chrX 17,529,998	C. elegans SUP-10 protein ;
50	ceh-10	W03A3.1	n/a	chrIII 5,800,012	ceh-10 encodes a member of the Paired-like class of homeodomain proteins; the CEH-10 homeodomain is closely related to the homeodomains of two vertebrate retina proteins (Chx10 from mice and Vsx-1 from goldfish); ceh-10 is required for CAN cell fate specification and migration, complete loss of ceh-10 function results in failure of CAN cell migration and loss of expression of CEH-23 and CEH-10 itself in the CAN and AIY interneurons; CEH-10, along with TTX-3 and CEH-23, constitutes a regulatory cascade of transcription factors that controls all sub-type specific features of the AIY interneurons.