UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	K08H10.9	K08H10.9	2e-103	chrV 9,992,294	contains similarity to Pfam domain PF04051 Transport protein particle (TRAPP) component, Bet3 contains similarity to Interpro domain IPR007194 (Transport protein particle (TRAPP) component, Bet3)
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	fbxb-57	F55C9.4	n/a	chrV 19,289,333	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
4	fbxb-105	F08D12.8	n/a	chrII 2,770,341	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
5	F46C5.4	F46C5.4	n/a	chrII 8,837,535
6	acbp-6	Y17G7B.1	n/a	chrII 11,972,918	C. elegans ACBP-6 protein; contains similarity to Pfam domain PF00887 Acyl CoA binding protein contains similarity to Interpro domains IPR014352 (FERM/acyl-CoA-binding protein, 3-helical bundle), IPR000582 (Acyl-CoA-binding protein, ACBP)
7	Y106G6H.9	Y106G6H.9	n/a	chrI 10,455,014	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
8	F36H2.2	F36H2.2	n/a	chrI 9,247,697	contains similarity to Pfam domain PF01733 Nucleoside transporter contains similarity to Interpro domains IPR002259 (Delayed-early response protein/equilibrative nucleoside transporter), IPR016196 (MFS general substrate transporter)
9	pri-2	W02D9.1	n/a	chrI 12,530,247	pri-2 encodes a homolog of the DNA polymerase alpha-primase subunit C that is required in embryos for the normal timing of embryonic cell divisions (much as DIV-1 is) and for normal mitosis in the germline.
10	F28C6.1	F28C6.1	n/a	chrII 8,591,963	F28C6.1 encodes an AP-2-like transcription factor that is ~60% identical to that of F28C6.2 which lies immediately adjacent to F28C6.1 on chromosome II; loss of F28C6.1 activity via large-scale RNAi experiments results in embryonic and larval lethality.
11	F52D10.2	F52D10.2	n/a	chrX 11,590,643	contains similarity to Interpro domains IPR011993 (Pleckstrin homology-type), IPR006020 (Phosphotyrosine interaction region)
12	B0285.3	B0285.3	n/a	chrIII 4,342,632	contains similarity to Interpro domain IPR002952 (Eggshell protein)
13	C02B8.2	C02B8.2	n/a	chrX 8,144,673
14	C47G2.4	C47G2.4	n/a	chrII 11,292,129	contains similarity to Pfam domain PF04791 LMBR1-like membrane protein contains similarity to Interpro domain IPR006876 (LMBR1-like conserved region)
15	T11B7.1	T11B7.1	n/a	chrIV 8,841,747	contains similarity to Mus musculus Girdin (Girders of actin filament) (Coiled-coil domain-containingsprotein 88A) (Akt phosphorylation enhancer) (APE) (Hook-relatedsprotein 1) (HkRP1) (G alpha-interacting vesicle-associated protein)s(GIV).; SW:Q5SNZ0
16	F09E5.11	F09E5.11	n/a	chrII 5,357,780	F09E5.11 encodes a divergent ortholog of S. cerevisiae VPH2/VMA12; like VPH2, F09E5.11 may be required for vacuolar proton-translocating ATPase (V-ATPase) assembly in the endoplasmic reticulum.
17	mcm-5	R10E4.4	n/a	chrIII 4,289,788	C. elegans MCM-5 protein; contains similarity to Pfam domain PF00493 MCM2/3/5 family contains similarity to Interpro domains IPR016027 (Nucleic acid-binding, OB-fold-like), IPR012340 (Nucleic acid-binding, OB-fold), IPR008048 (MCM protein 5), IPR003593 (AAA+ ATPase, core), IPR001208 (MCM)
18	C29F9.12	C29F9.12	n/a	chrIII 121,876
19	hst-2	C34F6.4	n/a	chrX 11,205,546	hst-2 encodes the C. elegans ortholog of the heparan sulfate modifying enzyme 2O-sulfotransferase; by homology, HST-2 is predicted to function in heparan sulfate biosynthesis by catalyzing the chain-modifying sulfation of the C2 hydroxyl group of hexuronic acid; during development, hst-2 activity is required for normal body size, cell migration, and nervous system development; an hst-2::gfp reporter fusion is first expressed in embryos, continuing on through adulthood; expression is detected in many tissues, including the pharynx, hypodermis, muscles, vulva, and distal tip cells (DTCs) of the somatic gonad.
20	F02H6.4	F02H6.4	n/a	chrIV 14,217,678	contains similarity to Saccharomyces cerevisiae GTPase, required for general translation initiation by promoting Met-tRNAiMet binding to ribosomes and ribosomal subunit joining; homolog of bacterial IF2; SGD:YAL035W
21	K03A11.1	K03A11.1	n/a	chrX 13,053,489	contains similarity to Interpro domain IPR001130 (Deoxyribonuclease, TatD-related)
22	C05C8.8	C05C8.8	n/a	chrV 7,253,723	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
23	str-245	F32A7.7	n/a	chrI 14,853,699	C. elegans STR-245 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR001991 (Sodium:dicarboxylate symporter)
24	egl-26	C23H3.1	n/a	chrII 70,469	egl-26 encodes a protein that contains an H-box and an NC domain that is a member of the LRAT (lecithin retinol acyltransferase) subfamily of the NlpC/P60 superfamily of enzymes; egl-26 activity is required for fertility, egg laying, and vulval development, specifically the connection of the uterus to the vulva mediated by proper morphogenesis of vulF, the most dorsal vulval cell; EGL-26 is an apical membrane protein that is expressed in many cells, including vulF, and appears to be expressed near the vulva and uterus only during the L4 larval stage; EGL-26 membrane localization is necessary for its function.
25	vet-6	F44F1.7	n/a	chrI 13,271,377	vet-6 encodes a protein that contains a spectrin repeat; vet-6 is preferentially transcribed in embryos prior to gastrulation.
26	W06A11.2	W06A11.2	n/a	chrII 4,060,321
27	efn-4	F56A11.3	n/a	chrIV 563,657	efn-4 encodes a member of the ephrin family of ligands that affects neuroblast migrations during closure of the ventral gastrulation cleft and subsequent epidermal morphogenesis, possibly functioning independently of EFN-1, EFN-2, EFN-3, and the VAB-1 receptor during morphogenesis; can interact with VAB-1 in vitro, and is expressed in neural and epidermal precursors at the 100-cell stage, in head neurons, pharyngeal cells, lateral and tail neurons, and in the ectoderm during epidermal enclosure.
28	ZK402.5	ZK402.5	n/a	chrX 1,399,783	contains similarity to Pfam domain PF04435 Domain of unknown function (DUF545) contains similarity to Interpro domain IPR006570 (SPK)
29	R05H5.5	R05H5.5	n/a	chrII 10,200,234	contains similarity to Pfam domain PF04161 Arv1-like family contains similarity to Interpro domains IPR007290 (Arv1-like protein), IPR015964 (Cytochrome C oxidase subunit II-like, transmembrane region)
30	btb-13	ZC204.11	n/a	chrII 1,654,256	C. elegans BTB-13 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000209 (Peptidase S8 and S53, subtilisin, kexin, sedolisin), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
31	ubc-16	Y54E5B.4	n/a	chrI 14,822,998	C. elegans UBC-16 protein; contains similarity to Pfam domain PF00179 Ubiquitin-conjugating enzyme contains similarity to Interpro domains IPR000608 (Ubiquitin-conjugating enzyme, E2), IPR016135 (Ubiquitin-conjugating enzyme/RWD-like)
32	T28C6.3	T28C6.3	n/a	chrIV 8,820,742	contains similarity to Homo sapiens HIV Tat-specific factor 1; ENSEMBL:ENSP00000218364
33	fbxb-119	B0462.3	n/a	chrV 18,319,134	C. elegans FBXB-119 protein; contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
34	F58E1.11	F58E1.11	n/a	chrII 1,692,234	contains similarity to Interpro domain IPR002034 (Alpha-isopropylmalate/homocitrate synthase, conserved site)
35	sdz-30	T04D3.2	n/a	chrI 13,307,433	C. elegans SDZ-30 protein; contains similarity to Interpro domain IPR002048 (Calcium-binding EF-hand)
36	K09E3.4	K09E3.4	n/a	chrX 17,119,682
37	K09E3.6	K09E3.6	n/a	chrX 17,114,487	contains similarity to Pfam domain PF03353 DUF278 contains similarity to Interpro domain IPR005020 (Protein of unknown function DUF278)
38	set-4	C32D5.5	n/a	chrII 6,330,534	set-4 encodes a putative histone H4 lysine-20 methyltransferase; SET-4 is orthologous to Drosophila SUV4-20, and to human SUV420H1 (OMIM:610881) and SUV420H2; neither set-4(n4600) nor set-4(RNAi) have any obvious phenotypes.
39	nhr-273	T12C9.1	n/a	chrII 4,436,140	C. elegans NHR-273 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
40	R166.3	R166.3	n/a	chrII 10,538,486	The R166.3 gene encodes an unfamiliar protein, with homologs in yeast and archaea, that is orthologous to the human gene ALPORT SYNDROME, MENTAL RETARDATION, MIDFACE HYPOPLASIA, AND ELLIPTOCYTOSIS CHROMOSOMAL REGION GENE 1 (AMMECR1; OMIM:300195); AMMECR1, when mutated, may be at least partially responsible for mental retardation, midface hypoplasia, or elliptocytosis.
41	sdz-37	ZK673.10	n/a	chrII 10,465,005	C. elegans SDZ-37 protein ;
42	C14B1.8	C14B1.8	n/a	chrIII 3,719,182	C14B1.8 encodes a coiled-coil protein.
43	R07E5.3	R07E5.3	n/a	chrIII 4,405,506	The R07E5.3 gene encodes a homolog of SNF5/Ini1, a component of the SWI/SNF complex that is conserved from yeast to mammals and that is involved in chromatin remodeling; R07E5.3 may be involved in asymmetric cell division of the T cells.
44	sdz-38	ZK892.7	n/a	chrII 9,981,301	C. elegans SDZ-38 protein; contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
45	B0454.5	B0454.5	n/a	chrII 3,039,835	contains similarity to Homo sapiens 21 kDa protein; VG:OTTHUMP00000165983
46	Y73C8C.8	Y73C8C.8	n/a	chrV 3,112,017	contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR001965 (Zinc finger, PHD-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011016 (Zinc finger, variant RING-type)
47	his-2	T10C6.13	n/a	chrV 16,041,899	his-2 encodes an H3 histone; his-2 is contained within the histone gene cluster HIS1.
48	C33H5.7	C33H5.7	n/a	chrIV 7,775,184	contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
49	T08E11.5	T08E11.5	n/a	chrII 1,822,035
50	T02E1.2	T02E1.2	n/a	chrI 8,221,514	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8IJZ2