UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	K08F4.3	K08F4.3	2e-90	chrIV 10,129,732	contains similarity to Pfam domain PF05753 Translocon-associated protein beta (TRAPB) contains similarity to Interpro domain IPR008856 (Translocon-associated beta)
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
4	inx-9	ZK792.3	n/a	chrIV 11,677,349	inx-9 encodes an innexin, an integral transmembrane channel protein that is a structural component of invertebrate gap junctions; although the precise role of INX-9 in C. elegans development and/or behavior is not yet known, INX-9 may play a role in gonad or germline development, as INX-9 expression is detected solely in the sheath cells of the somatic gonad and particularly, the sheath cells in contact with proximal oocytes.
5	C06A5.6	C06A5.6	n/a	chrI 5,984,551
6	W02B12.4	W02B12.4	n/a	chrII 11,457,473	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domain IPR002018 (Carboxylesterase, type B)
7	vha-18	F52E1.10	n/a	chrV 8,412,615	vha-18 encodes an an ortholog of subunit H of the cytoplasmic (V1) domain of vacuolar proton-translocating ATPase (V-ATPase); VHA-18 and VHA-15 are co-orthologs; VHA-18 is a predicted cytosolic stator (stalk) component.
8	clec-38	T25E12.10	n/a	chrV 16,734,718	C. elegans CLEC-38 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
9	F58A4.2	F58A4.2	n/a	chrIII 9,600,293	contains similarity to Musca domestica Hexamerin (Fragment).; TR:Q9U6B2
10	old-2	ZK938.5	n/a	chrII 9,848,462	old-2 encodes a transmembrane protein tyrosine kinase (also known as 'kin-28') that affects mean and maximum life span with multiple paralogs in C. elegans; the expression of old-2 was experimentally verified by RT-PCR.
11	pax-3	F27E5.2	n/a	chrII 10,149,568	pax-3 encodes a divergent paired-like homeodomain protein that does not belong to the Q50, K50, or S50 classes; PAX-3 is required for locomotion and vulval development; pax-3(RNAi) animals have consistent Pvl and Unc phenotypes (as well as less consistent Bmd, Rup, and Stp phenotypes).
12	mex-5	W02A2.7	n/a	chrIV 13,354,881	mex-5 encodes a novel protein that contains two CCCH zinc finger motifs; maternally provided MEX-5, which functions partly redundantly with the highly similar CCCH finger protein MEX-6, is essential for transducing polarity cues and establishing soma/germline asymmetry in the early embryo; in regulating soma/germline asymmetry, MEX-5 interacts with, and activates, the SOCS-box protein ZIF-1, which functions as part of an E3 ubiquitin ligase complex that degrades germ plasm proteins in somatic blastomeres; accordingly, ectopic expression of MEX-5 throughout the early embryo results in reduced expression of germline proteins in germline blastomeres; MEX-5 is a cytoplasmic protein expressed at uniform levels in oocytes and newly fertilized eggs; from the 1-cell to 4-cell stages of embryogenesis, MEX-5 expression is dynamic, with highest levels seen in the anterior AB blastomere and, for a time, its daughters, the anterior portion of the P1 blastomere, P1 centrosomes (both, then posterior only), and the EMS and C blastomeres; the asymmetric distribution of MEX-5 in early embryos depends upon wild-type activity of the PAR and OMA-1 proteins.
13	bra-2	F23H11.1	n/a	chrIII 911,744	The bra-2 gene encodes a homolog of the human BMP receptor-associated molecule (BRAM1), paralogous to bra-1, that may act upon the SMA-6 TGF-beta signalling pathway
14	B0244.9	B0244.9	n/a	chrIII 5,730,515	contains similarity to Interpro domains IPR005838 (Type III secretion system inner membrane P protein), IPR001865 (Ribosomal protein S2)
15	ttr-3	K03H1.3	n/a	chrIII 9,926,034	K03H1.3 encodes a protein containing a predicted signal sequence followed by a transthyretin-like domain; the product of K03H1.3 belongs to a family of apparently nematode-specific proteins whose function is not yet known.
16	srp-1	C05E4.3	n/a	chrV 754,193	srp-1 encodes an ovalbumin-like serpin (ov-serpin) member of the serine protease inhibitor superfamily; by homology, SRP-1 is predicted to function as a suicide substrate that inhibits the proteolytic activity of serine proteases; however, as loss of srp-1 function via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, the precise role of SRP-1 in C. elegans development and/or behavior is not yet known.
17	srd-4	ZK863.5	n/a	chrV 12,185,574	C. elegans SRD-4 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000276 (GPCR, rhodopsin-like)
18	Y40H7A.10	Y40H7A.10	n/a	chrIV 15,212,835	contains similarity to Pfam domains PF08246 (Cathepsin propeptide inhibitor domain (I29)) , PF00112 (Papain family cysteine protease) contains similarity to Interpro domains IPR013128 (Peptidase C1A, papain), IPR000169 (Peptidase, cysteine peptidase active site), IPR013201 (Proteinase inhibitor I29, cathepsin propeptide), IPR000668 (Peptidase C1A, papain C-terminal)
19	col-51	T28F2.8	n/a	chrI 3,654,613	col-51 encodes a cuticle collagen.
20	srz-54	Y102A5C.25	n/a	chrV 16,981,243	C. elegans SRZ-54 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
21	btb-7	F45C12.12	n/a	chrII 1,713,745	C. elegans BTB-7 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
22	F35C11.5	F35C11.5	n/a	chrII 8,254,199	contains similarity to Interpro domains IPR016090 (Phospholipase A2), IPR013090 (Phospholipase A2, active site)
23	C04E6.11	C04E6.11	n/a	chrV 5,915,960	contains similarity to Homo sapiens Leucine-rich PPR motif-containing protein, mitochondrial precursor; ENSEMBL:ENSP00000260665
24	VC27A7L.1	VC27A7L.1	n/a	chrV 12,165,914	contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
25	srj-25	C05E4.10	n/a	chrV 735,347	C. elegans SRJ-25 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR001991 (Sodium:dicarboxylate symporter)
26	srbc-29	C02A12.2	n/a	chrV 3,470,161	C. elegans SRBC-29 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
27	F20H11.5	F20H11.5	n/a	chrIII 6,588,571	F20H11.5 encodes a putative secreted D-aspartate oxidase (DASPO), paralogous to C47A10.5 and F18E3.7; recombinant F20H11.5 protein is insoluble when expressed in E. coli, and thus has not yet been tested in vitro for activity; F20H11.5 is expressed in a head mesodermal cell, hypodermis, other head cells, and vulva.
28	clec-148	F40G9.10	n/a	chrIII 175,220	C. elegans CLEC-148 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR002352 (Eosinophil major basic protein), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
29	F47B8.6	F47B8.6	n/a	chrV 14,329,569	contains similarity to Drosophila heteroneura Aminopeptidase N (Fragment).; TR:O61534
30	W02D7.4	W02D7.4	n/a	chrV 8,297,041	contains similarity to Interpro domain IPR016181 (Acyl-CoA N-acyltransferase)
31	srx-56	C03G6.2	n/a	chrV 7,374,979	C. elegans SRX-56 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
32	W05B2.4	W05B2.4	n/a	chrIII 10,975,818	contains similarity to Pfam domain PF08393 Dynein heavy chain, N-terminal region 2 contains similarity to Interpro domains IPR011010 (DNA breaking-rejoining enzyme, catalytic core), IPR013602 (Dynein heavy chain, N-terminal region 2)
33	Y18D10A.23	Y18D10A.23	n/a	chrI 12,868,302	contains similarity to Pfam domain PF01490 Transmembrane amino acid transporter protein contains similarity to Interpro domains IPR002091 (Aromatic amino acid permease), IPR013057 (Amino acid transporter, transmembrane), IPR006634 (TRAM, LAG1 and CLN8 homology)
34	T28F4.4	T28F4.4	n/a	chrI 7,488,371	contains similarity to Brugia malayi Putative uncharacterized protein BMBAC01P19.05a.; TR:Q8IHI4
35	K07A1.1	K07A1.1	n/a	chrI 9,583,089	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8IBJ6
36	mat-2	W10C6.1	n/a	chrII 11,116,985	mat-2 encodes a subunit of the anaphase-promoting complex or cyclosome (APCC) which is a multi-subunit E3 ubiquitin ligase that targets proteins for degradation during the metaphase-to-anaphase transition of the cell cycle; mat-2 is required for chromosome segregation during meiosis I and is involved in polarity specification of the anterior/posterior axis in the developing embryo.
37	C16A11.6	C16A11.6	n/a	chrII 4,237,141
38	Y57G11C.20	Y57G11C.20	n/a	chrIV 14,844,297	contains similarity to Interpro domain IPR000003 ()
39	str-182	C12D8.12	n/a	chrV 10,232,595	C. elegans STR-182 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
40	K07A1.13	K07A1.13	n/a	chrI 9,584,354	contains similarity to White spot syndrome virus Wsv319.; TR:Q8VAS3
41	acl-1	F59F4.4	n/a	chrX 15,850,758	acl-1 encodes a 1-acyl-sn-glycerol-3-phosphate acyltransferase; ACL-1 is predicted to be a membrane protein that plays a role in phospholipid biosynthesis, but as loss of acl-1 activity via large-scale RNAi experiments results in no obvious defects, the precise role of ACL-1 in C. elegans development and/or behavior is not yet known.
42	T25C8.1	T25C8.1	n/a	chrIII 13,611,268	contains similarity to Interpro domains IPR002345 (Lipocalin), IPR000577 (Carbohydrate kinase, FGGY)
43	C13G5.2	C13G5.2	n/a	chrIII 8,617,549	contains similarity to Interpro domain IPR001680 (WD40 repeat)
44	ttr-4	F40F12.1	n/a	chrIII 9,916,526	sdz-17 encodes a protein that contains a transthyretin-like domain; SDZ-17 belongs to a family of apparently nematode-specific proteins whose function is not yet known; early zygotic expression of sdz-17 is dependent upon the SKN-1 transcription factor.
45	F08F1.3	F08F1.3	n/a	chrX 8,430,035
46	C13A2.10	C13A2.10	n/a	chrV 7,274,350	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
47	W01B6.6	W01B6.6	n/a	chrIV 10,081,890	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase)
48	C05D11.13	C05D11.13	n/a	chrIII 6,443,485	contains similarity to Drosophila melanogaster Flybase gene name is CG2839-PA;; FLYBASE:CG2839
49	T12D8.5	T12D8.5	n/a	chrIII 13,626,155	contains similarity to Treponema pallidum Nuclease sbcCD subunit C.; SW:SBCC_TREPA
50	srx-84	F35B12.1	n/a	chrV 11,599,872	C. elegans SRX-84 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)