UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	K08E7.6	K08E7.6	8e-141	chrIV 12,580,060	contains similarity to Aquifex aeolicus Probable DNA double-strand break repair rad50 ATPase.; SW:RA50_AQUAE
2	ndx-1	T26E3.2	n/a	chrI 12,680,484	The ndx-1 gene encodes a NUDIX hydrolase.
3	F15A2.7	F15A2.7	n/a	chrX 13,489,900	contains similarity to Xanthomonas campestris Exodeoxyribonuclease V beta chain.; TR:Q8P379
4	ctbp-1	F49E10.5	n/a	chrX 5,867,998	tag-45 encodes a D-isomer specific 2-hydroxyacid dehydrogenase.
5	sto-2	F32A6.5	n/a	chrX 5,309,627	C. elegans STO-2 protein; contains similarity to Pfam domain PF01145 SPFH domain / Band 7 family contains similarity to Interpro domains IPR001107 (Band 7 protein), IPR001972 (Stomatin)
6	pag-3	F45B8.4	n/a	chrX 14,952,780	pag-3 encodes a C2H2 zinc-finger protein orthologous to Drosophila SENSELESS, and to human GFI1 (OMIM:600871, mutated in neutropenia) and GFI1B (OMIM:604383); pag-3 is expressed in neurons (touch receptors, BDU interneurons, ventral cord motor neurons, and others); PAG-3 is required to repress the touch neuron-specific genes mec-4 and mec-7 in BDU neurons, but since this repression does not occur in touch neurons (which also have PAG-3), PAG-3 may require another protein or proteins for repression (such as PRK-1 or PRK-2, the C. elegans orthologs of human PIM-1); PAG-3 is also needed for normal neuroblast lineages in the ventral nerve cord, and for normal locomotion; pag-3 mutants have a reverse kinker uncoordinated phenotype, and occasional axonal guidance errors in the PLM and BDU neurons; PAG-3's similarity to GFI1 and GFIB falls mainly within residues 159-261, but within these residues (which overlap PAG-3's five zinc-finger domains in residues 126-265) the amino acid identity is 87%; pag-3 transcript quantities are doubled in pag-3 mutants, suggesting that PAG-3 inhibits its own gene.
7	elt-3	K02B9.4	n/a	chrX 13,939,895	The elt-3 gene encodes a GATA transcription factor expressed in the embryonic hypodermis; specifically, it is expressed in expressed in all of the major hypodermal cells except the lateral seam cells.
8	ZC84.4	ZC84.4	n/a	chrIII 9,211,781	ZC84.4 encodes a G protein-coupled receptor with acidic amino acids in the -3 position of its PDZ binding motif; ZC84.4 protein binds PDZ domain 10 of the multi-PDZ domain protein, MPZ-1, in GST pulldown experiments; by analogy with SER-1, the PDZ binding motif of ZC84.4 may enhance its signalling.
9	T04B8.1	T04B8.1	n/a	chrII 635,951
10	asic-2	T28F4.2	n/a	chrI 7,481,759	C. elegans ASIC-2 protein; contains similarity to Pfam domain PF00858 Amiloride-sensitive sodium channel contains similarity to Interpro domains IPR001873 (Na+ channel, amiloride-sensitive), IPR004726 (Degenerin)
11	unc-29	T08G11.5	n/a	chrI 8,899,525	unc-29 encodes an non-alpha subunit of the nicotinic acetylcholine receptor (nAChR) superfamily; UNC-29 is required for normal locomotion and egg-laying, and functions as a subunit of a ligand-gated ion channel that likely mediates fast actions of acetylcholine at neuromuscular junctions and in the nervous system; when coexpressed with LEV-1, a non-alpha nAChR subunit, and UNC-38 or UNC-63, alpha AChR subunits, the resulting multimer can form levamisole-gated channels; UNC-29 is expressed in body wall muscle.
12	M03C11.1	M03C11.1	n/a	chrIII 10,394,622	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
13	sox-3	F40E10.2	n/a	chrX 14,692,543	C. elegans SOX-3 protein; contains similarity to Pfam domain PF00505 HMG (high mobility group) box contains similarity to Interpro domains IPR000910 (High mobility group box, HMG1/HMG2), IPR009071 (High mobility group box, HMG), IPR000135 (High mobility group box, HMG1/HMG2, subgroup)
14	H28G03.3	H28G03.3	n/a	chrX 5,221,191
15	tsp-16	F01E11.4	n/a	chrX 6,995,740	C. elegans TSP-16 protein; contains similarity to Pfam domain PF00335 Tetraspanin family contains similarity to Interpro domains IPR000301 (CD9/CD37/CD63 antigen), IPR008952 (Tetraspanin), IPR013838 (Beta tubulin, autoregulation binding site)
16	nhr-216	T09D3.4	n/a	chrV 5,356,451	C. elegans NHR-216 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
17	sup-9	F34D6.3	n/a	chrII 2,685,863	sup-9 encodes one of 44 C. elegans TWK (two-P domain K+) potassium channel subunits that contain two pore-forming domains and four transmembrane domains; sup-9 was originally defined by gain-of-function mutations that result in defects in pharyngeal, body-wall, egg-laying, and enteric muscle activation; loss of sup-9 function via reversion or RNA-mediated interference (RNAi) does not result in any abnormalities suggesting that SUP-9 may function redundantly with other TWK channels; SUP-9 is expressed in neurons and muscle.
18	nhr-207	R07B7.14	n/a	chrV 12,097,016	C. elegans NHR-207 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR001728 (Thyroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
19	C01B12.2	C01B12.2	n/a	chrII 20,848	contains similarity to Pfam domain PF01342 SAND domain contains similarity to Interpro domains IPR010919 (SAND-like), IPR000770 (SAND)
20	aat-7	F54D12.3	n/a	chrII 1,389,233	aat-7 encodes a predicted amino acid transporter catalytic subunit; unlike catalytic subunits in other organisms, however, AAT-7 does not contain the highly conserved cysteine residue known to facilitate covalent interaction with a glycoprotein subunit, suggesting that AAT-7 does not require this residue for heterodimer formation or alternatively, does not require the glycoprotein subunit for function.
21	unc-130	C47G2.2	n/a	chrII 11,282,880	A member of the forkhead domain family of transcription factors that affects the generation of the AWA and ASG chemosensory neurons and is partially required for male tail morphogenesis and embryogenesis; it is expressed in the AWA and ASG precursors; it is required for the graded spatial expression of the UNC-129 TGF-beta guidance factor.
22	C16C10.9	C16C10.9	n/a	chrIII 4,156,357	contains similarity to Bacillus anthracis MutS2 family protein.; TR:Q81L40
23	srt-26	C24B9.2	n/a	chrV 2,716,136	C. elegans SRT-26 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
24	F28H7.7	F28H7.7	n/a	chrV 10,752,577	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
25	F49E10.1	F49E10.1	n/a	chrX 5,899,725	contains similarity to Pfam domain PF00566 TBC domain contains similarity to Interpro domain IPR000195 (RabGAP/TBC)
26	F44E7.7	F44E7.7	n/a	chrV 5,784,253	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
27	Y43F8A.5	Y43F8A.5	n/a	chrV 19,387,467	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
28	dmd-4	C27C12.6	n/a	chrX 14,859,502	C. elegans DMD-4 protein; contains similarity to Pfam domains PF00751 (DM DNA binding domain) , PF03474 (DMRTA motif) contains similarity to Interpro domains IPR005173 (DMRTA motif), IPR001275 (DM DNA-binding)
29	F23H11.7	F23H11.7	n/a	chrIII 918,259
30	C09F12.2	C09F12.2	n/a	chrX 11,055,383	contains similarity to Tetrahymena thermophila SB210 Putative uncharacterized protein.; TR:Q23C46
31	M176.4	M176.4	n/a	chrII 9,421,150	contains similarity to Pfam domain PF07947 YhhN-like protein contains similarity to Interpro domains IPR012506 (YhhN-like), IPR003492 (Batten's disease protein Cln3)
32	glb-3	C06H2.5	n/a	chrV 11,139,410	glb-3 encodes a globin with no obvious function in mass RNAi assays.
33	gcy-15	ZC239.7	n/a	chrII 3,194,642	gcy-15 encodes a membrane guanylyl cyclase.
34	mlt-8	W08F4.6	n/a	chrII 570,690	mlt-8 encodes a novel protein; during development, mlt-8 activity is required for molting; a mlt-8::gfp reporter is expressed in hypodermal cells and in a single posterior neuron.
35	Y47D3B.3	Y47D3B.3	n/a	chrIII 11,400,137	contains similarity to Homo sapiens Low-density lipoprotein receptor-related protein 2 precursor; ENSEMBL:ENSP00000263816
36	F08F3.1	F08F3.1	n/a	chrV 5,447,387
37	acc-1	F58G6.4	n/a	chrIV 9,660,974	C. elegans ACC-1 protein; contains similarity to Pfam domains PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) , PF02932 (Neurotransmitter-gated ion-channel transmembrane region) contains similarity to Interpro domains IPR002289 (Gamma-aminobutyric-acid A receptor, beta subunit), IPR006028 (Gamma-aminobutyric acid A receptor), IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding), IPR006029 (Neurotransmitter-gated ion-channel transmembrane region)
38	glf-1	H04M03.4	n/a	chrIV 5,887,804	H04M03.4 encodes a UDP-galactopyranose mutase predicted to synthesize galactofuranose (Gal(f)) as a nucleotide sugar (UDP-Gal(f)); recombinant H04M03.4 has biochemical activity either in vivo (expressed in E. coli) or in vitro; orthologs of H04M03.4 are found in the urochordates Halocynthia and Ciona.
39	R05A10.3	R05A10.3	n/a	chrIV 14,175,025	contains similarity to Saccharomyces cerevisiae <b><u>C</u></b>onserved <b><u>O</u></b>ligomeric <b><u>G</u></b>olgi complex <b><u>1</u></b><br> Complexed with Cog8p; interacts with Cog2p; SGD:YGL223C
40	C39F7.5	C39F7.5	n/a	chrV 1,267,440	contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold)
41	srd-60	C13B7.3	n/a	chrV 2,420,332	C. elegans SRD-60 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
42	ZC190.5	ZC190.5	n/a	chrV 8,672,433
43	clc-2	C01C10.1	n/a	chrX 7,432,451	clc-2 encodes a claudin homolog, closely similar to CLC-1, that is required for normal cohesion of apical junctions in epithelia; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water; CLC-2 maintains the impermeability ('barrier function') of epithelia, since clc-1(RNAi) animals have abnormal permeability of the hypodermis to dyes; clc-2 is expressed in hypodermal seam cells, with two diffuse lines of CLC-2 protein.
44	nhr-63	C06C6.4	n/a	chrV 16,003,610	C. elegans NHR-63 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
45	ZC404.7	ZC404.7	n/a	chrV 6,779,108
46	M01G4.1	M01G4.1	n/a	chrIII 6,665,107
47	lev-1	F09E8.7	n/a	chrIV 13,176,746	lev-1 encodes an alpha subunit of nicotinic acetylcholine receptor (nAChR) which, when mutated, confers resistance to levamisole; LEV-1 is required for completely normal locomotion, and forms a cation channel when coexpressed with UNC-38 or UNC-63 and UNC-29; LEV-1 falls into the 'UNC-29' class of nAChR subunits, which includes UNC-29, ACR-2, and ACR-3.
48	C17E4.11	C17E4.11	n/a	chrI 9,420,385	contains similarity to Pfam domain PF08241 Methyltransferase domain contains similarity to Interpro domain IPR013216 (Methyltransferase type 11)
49	C54G4.2	C54G4.2	n/a	chrI 8,007,875	contains similarity to Saccharomyces cerevisiae protein of unknown function; SGD:YNR051C
50	str-39	F37B4.12	n/a	chrV 2,878,851	C. elegans STR-39 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR002355 (Multicopper oxidase, copper-binding site)