UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	K06B9.4	K06B9.4	0	chrIV 4,192,228
2	tag-229	W09G3.3	n/a	chrI 13,804,628	C. elegans TAG-229 protein; contains similarity to Pfam domain PF08755 Hemimethylated DNA-binding protein YccV like contains similarity to Interpro domain IPR011722 (Hemimethylated DNA-binding region)
3	K01D12.6	K01D12.6	n/a	chrV 12,399,785	contains similarity to Homo sapiens Isoform 1 of Protein FAM73B; ENSEMBL:ENSP00000351138
4	C02C2.4	C02C2.4	n/a	chrIII 7,863,860	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
5	tag-72	C25A1.3	n/a	chrI 10,160,921	C. elegans TAG-72 protein; contains similarity to Pfam domains PF03291 (mRNA capping enzyme) , PF08242 (Methyltransferase domain) , PF08241 (Methyltransferase domain) contains similarity to Interpro domains IPR004971 (mRNA capping enzyme, large subunit), IPR016899 (mRNA (guanine-N(7))-methyltransferase), IPR002296 (N6 adenine-specific DNA methyltransferase, N12 class), IPR013217 (Methyltransferase type 12), IPR013216 (Methyltransferase type 11)
6	scc-3	F18E2.3	n/a	chrV 12,765,914	scc-3 encodes a cohesin complex subunit homologous to Saccharomyces cerevisiae Irr1p/Scc3p; SCC-3 is required during meiosis for synaptonemal complex formation and sister chromatid cohesion, proper localization of REC-8 to chromosomes, mitotic chromosome segregation, embryonic development, and vulval morphogenesis; in embryos, SCC-3 forms a cohesin complex with SCC-1, SMC-1, SMC-3, and TIM-1, a HEAT/Armadillo repeat-containing protein related to Drosophila TIMELESS; in the germline, SCC-3 associates with chromatin of transistion zone nuclei, assembles along the longitudinal axes of synapsed chromosomes at pachytene, and unlike other cohesins, localizes throughout chromatin at diakinesis; SCC-3 localization requires TIM-1, and SCC-3 and REC-8 are mutually required for chromatin localization.
7	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
8	W02G9.4	W02G9.4	n/a	chrV 2,668,540	contains similarity to Pfam domain PF00431 CUB domain contains similarity to Interpro domain IPR000859 (CUB)
9	F53F4.3	F53F4.3	n/a	chrV 13,592,537	F53F4.3 encodes a putative alpha-tubulin folding cofactor B, orthologous to human CKAP1 (OMIM:601303); F53F4.3 is dispensable in early embryos for microtubule nucleation or elongation, and has no obvious function in mass RNAi assays.
10	plc-4	R05G6.8	n/a	chrIV 7,511,060	C. elegans PLC-4 protein; contains similarity to Pfam domains PF00168 (C2 domain) , PF00387 (Phosphatidylinositol-specific phospholipase C, Y domain) , PF09279 (Phosphoinositide-specific phospholipase C, efhand-like) , PF00036 (EF hand) , PF00388 (Phosphatidylinositol-specific phospholipase C, X domain) contains similarity to Interpro domains IPR015359 (Phospholipase C, phosphoinositol-specific, EF-hand-like), IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand), IPR001192 (Phospholipase C, phosphoinositol-specific, C-terminal (PLC)), IPR001849 (Pleckstrin-like), IPR011993 (Pleckstrin homology-type), IPR000909 (Phospholipase C, phosphatidylinositol-specific , X region), IPR001711 (Phospholipase C, phosphatidylinositol-specific, Y domain), IPR013841 (Phospholipase C, phosphatidylinositol-specific , X and Y boxes), IPR000008 (C2 calcium-dependent membrane targeting)
11	C03H5.3	C03H5.3	n/a	chrII 387,056	contains similarity to Interpro domain IPR002408 (Natriuretic peptide, brain type)
12	F19F10.9	F19F10.9	n/a	chrV 7,573,793	The F19F10.9 gene encodes a homolog of the human SART1 gene, which encodes a protein recognised by IgE that may be involved in atopic disease.
13	F27C1.3	F27C1.3	n/a	chrI 5,426,839	contains similarity to Pfam domain PF03057 Protein of unknown function contains similarity to Interpro domains IPR004296 (Protein of unknown function DUF236), IPR002952 (Eggshell protein)
14	M03C11.3	M03C11.3	n/a	chrIII 10,409,775	contains similarity to Saccharomyces cerevisiae Essential protein required for the maturation of 25S rRNA and 60S ribosomal subunit assembly, localizes to the nucleolus; SGD:YKL172W
15	R08D7.1	R08D7.1	n/a	chrIII 8,966,795	contains similarity to Drosophila pseudoobscura GA12417-PA (Fragment).; TR:Q293H8
16	T22B11.5	T22B11.5	n/a	chrIV 4,700,455	The T22B11.5 gene encodes an ortholog of the human gene OGDH, which when mutated leads to alpha-ketoglutarate deficiency (OMIM:203740); the T22B11.5 protein is predicted to be mitochondrial with 68% accuracy.
17	ZK632.5	ZK632.5	n/a	chrIII 9,810,489	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:O97236
18	F17B5.2	F17B5.2	n/a	chrI 13,192,171	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domains IPR002656 (Acyltransferase 3), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
19	tag-353	F25D7.2	n/a	chrI 10,401,993	C. elegans TAG-353 protein; contains similarity to Interpro domain IPR000626 (Ubiquitin)
20	gly-20	C03E10.4	n/a	chrV 11,284,282	gly-20 is orthologous to the human gene MANNOSYL (ALPHA-1,6-)-GLYCOPROTEIN BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE (MGAT2; OMIM:602616), which when mutated leads to carbohydrate-deficient glycoprotein syndrome, type II.
21	F33H2.2	F33H2.2	n/a	chrI 15,025,433	contains similarity to Homo sapiens Protein FAM91A1; ENSEMBL:ENSP00000335082
22	C47E12.3	C47E12.3	n/a	chrIV 10,000,452	contains similarity to Pfam domain PF01532 Glycosyl hydrolase family 47 contains similarity to Interpro domain IPR001382 (Glycoside hydrolase, family 47)
23	Y47G7B.2	Y47G7B.2	n/a	chrII 2,706,989
24	git-1	F14F3.2	n/a	chrX 10,526,597	C. elegans GIT-1 protein; contains similarity to Pfam domains PF01412 (Putative GTPase activating protein for Arf) , PF00023 (Ankyrin repeat) (2)contains similarity to Interpro domains IPR013724 (Spa2 homology (SHD) of GIT), IPR001164 (Arf GTPase activating protein), IPR002110 (Ankyrin)
25	ddx-23	F01F1.7	n/a	chrIII 5,851,012	C. elegans DDX-23 protein; contains similarity to Pfam domains PF00270 (DEAD/DEAH box helicase) , PF00271 (Helicase conserved C-terminal domain) contains similarity to Interpro domains IPR011545 (DNA/RNA helicase, DEAD/DEAH box type, N-terminal), IPR000629 (RNA helicase, ATP-dependent, DEAD-box, conserved site), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR014014 (RNA helicase, DEAD-box type, Q motif), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
26	btf-1	F15D4.1	n/a	chrII 13,207,846	btf-1 encodes a member of the TBP-associated family (TAF), with weak similarity to human TBP-associated factor 172.
27	K08F4.1	K08F4.1	n/a	chrIV 10,124,631	contains similarity to Pfam domain PF00004 ATPase family associated with various cellular activities (AAA) contains similarity to Interpro domains IPR003959 (AAA ATPase, core), IPR001199 (Cytochrome b5), IPR003593 (AAA+ ATPase, core)
28	B0001.5	B0001.5	n/a	chrIV 12,142,216	contains similarity to Saccharomyces cerevisiae Gtpase-activating protein activity toward the essential bud-site assembly GTPase Cdc42; SGD:YPL115C
29	gex-3	F28D1.10	n/a	chrIV 12,406,527	The gex-3 gene encodes a homolog of NAP1/NCKAP1, a mammalian protein ligand of the small GTPase Rac1, and of Drosophila HEM2/NAP1/KETTE; gex-3 is required for tissue morphogenesis and cell migrations; in gex-3 mutants, cells differentiate properly but fail to become organized.
30	F17A9.3	F17A9.3	n/a	chrV 6,106,582	contains similarity to Pfam domain PF07716 Basic region leucine zipper contains similarity to Interpro domains IPR011700 (Basic leucine zipper), IPR004827 (Basic-leucine zipper (bZIP) transcription factor)
31	mut-15	T01C3.8	n/a	chrV 15,003,779	C. elegans MUT-15 protein ;
32	F20B6.5	F20B6.5	n/a	chrX 4,199,245	contains similarity to Homo sapiens Conserved hypothetical protein; VG:OTTHUMP00000076919
33	vps-54	T21C9.2	n/a	chrV 10,571,379	The vps-54 gene encodes an ortholog of VPS54 in S. cerevisiae, a protein involved in vacuolar trafficking.
34	T14B4.1	T14B4.1	n/a	chrII 6,739,132
35	T01D3.5	T01D3.5	n/a	chrV 13,714,119	contains similarity to Pfam domain PF02535 ZIP Zinc transporter contains similarity to Interpro domain IPR003689 (Zinc/iron permease)
36	K01A11.3	K01A11.3	n/a	chrIII 3,450,547	contains similarity to Pfam domain PF00443 (Ubiquitin carboxyl-terminal hydrolases family 2)
37	C05D11.10	C05D11.10	n/a	chrIII 6,431,356	contains similarity to Interpro domain IPR016027 (Nucleic acid-binding, OB-fold-like)
38	C44H4.4	C44H4.4	n/a	chrX 14,586,632	contains similarity to Homo sapiens 155 kDa protein; ENSEMBL:ENSP00000381978
39	ncbp-1	F37E3.1	n/a	chrI 6,423,903	F37E3.1 encodes a putative nuclear cap-binding complex subunit ('CBP80') orthologous to budding yeast STO1 and human NCBP1 (OMIM:600469); in RNAi assays, F37E3.1 is required for embryonic and vulval development, normal locomotion, and general viability; by orthology to NCBP1, F37E3.1 is expected to participate in nonsense-mediated mRNA decay via a pioneer round of translation; F37E3.1(RNAi) induces expression of a gpdh-1::GFP transgene, perhaps because F37E3.1 prevents protein misfolding.
40	C49H3.8	C49H3.8	n/a	chrIV 7,901,218	contains similarity to Pfam domain PF00022 Actin contains similarity to Interpro domains IPR001478 (PDZ/DHR/GLGF), IPR004000 (Actin/actin-like), IPR013126 (Heat shock protein 70)
41	R01H10.7	R01H10.7	n/a	chrIII 10,264,464	contains similarity to Interpro domain IPR001849 (Pleckstrin-like)
42	syn-3	F55A11.2	n/a	chrV 11,766,040	C. elegans SYN-3 protein; contains similarity to Pfam domains PF00804 (Syntaxin) , PF05739 (SNARE domain) contains similarity to Interpro domains IPR010989 (t-SNARE), IPR006011 (Syntaxin, N-terminal), IPR000727 (Target SNARE coiled-coil region), IPR006012 (Syntaxin/epimorphin, conserved site)
43	F10C2.4	F10C2.4	n/a	chrV 12,043,441	F10C2.4 encodes a homolog of the DNA polymerase delta complex subunit A that is required in embryos for the normal timing of embryonic cell divisions (much as DIV-1 is) and, also, for normal chromosome segregation (probably because of defective DNA replication).
44	Y32B12B.2	Y32B12B.2	n/a	chrV 16,544,097	contains similarity to Vitis vinifera Putative uncharacterized protein.; TR:A5AD22
45	F31D4.2	F31D4.2	n/a	chrV 20,838,947	contains similarity to Pfam domain PF01937 Protein of unknown function DUF89 contains similarity to Interpro domains IPR000408 (Regulator of chromosome condensation, RCC1), IPR002791 (Protein of unknown function DUF89)
46	C01G6.5	C01G6.5	n/a	chrII 9,277,455	contains similarity to Pfam domain PF00498 FHA domain contains similarity to Interpro domains IPR005819 (Histone H5), IPR008984 (SMAD/FHA domain), IPR001965 (Zinc finger, PHD-type), IPR000253 (Forkhead-associated), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011011 (Zinc finger, FYVE/PHD-type)
47	C07H6.4	C07H6.4	n/a	chrIII 7,501,398	contains similarity to Pfam domains PF01805 (Surp module) , PF00076 (RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)) contains similarity to Interpro domains IPR006569 (Regulation of nuclear pre-mRNA protein), IPR000061 (SWAP/Surp), IPR012677 (Nucleotide-binding, alpha-beta plait), IPR008942 (ENTH/VHS), IPR000504 (RNA recognition motif, RNP-1)
48	C03H5.2	C03H5.2	n/a	chrII 390,779	C03H5.2 encodes a transporter of UDP-N-acetylglucosamine (UDP-GlcNAc) and UDP-N-acetylgalactosamine (UDP-GalNAc), orthologous to human SLC35A3 (OMIM:605632); CO3H5.2 is redundantly required, with its paralog SRF-3, for normal progression of oocytes through proximal gonads and for normal gonad morphology; C03H5.2 is expressed in many tissues, including pharynx, intestine, pharyngeal gland cells, seam cells, spermatheca, vulva, various muscles, hypodermis, and neurons; C03H5.2 transports both UDP-GlcNAc and UDP-GalNAc independently and simultaneously, with these two molecules neither competing with one another nor being transported as a heterodimer; C03H5.2's two transport activities are genetically separable, since an internally deleted version of C03H5.2 (lacking only 16 residues) retains normal levels of UDP-GlcNAc transport while losing 85-90% of its UDP-GalNAc transport activity; C03H5.2's activity has been experimentally validated through heterologous expression in budding yeast Golgi apparatus, and mutation of C03H5.2 in conserved residues greatly reduces this activity.
49	cash-1	K07C5.8	n/a	chrV 10,364,141	cash-1 encodes an ortholog of Drosophila CKA and the human striatins STRN, STRN3, and STRN4 that is required for vulval development; CASH-1 has an N-terminal region which may bind caveolin or calmodulin, and a C-terminal region with five tandem WD domains; by its orthology with CKA and striatins, CASH-1 is predicted to act as a scaffold linking signal transduction proteins (such as JKK-1 and JNK-1) to transcription factors (such as JUN-1 or FOS-1); CASH-1 is expressed broadly, in both larval and adult pharynx, intestine, rectal epithelium, hypodermis, and neurons, as well as the developing vulva and the adult reproductive system.
50	oxi-1	Y39A1C.2	n/a	chrIII 10,862,495	C. elegans OXI-1 protein; contains similarity to Pfam domain PF00632 HECT-domain (ubiquitin-transferase) contains similarity to Interpro domain IPR000569 (HECT)