UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	srx-29	K06B4.9	2e-171	chrV 15,697,466	C. elegans SRX-29 protein ;
2	sra-25	T26E3.9	n/a	chrI 12,687,150	C. elegans SRA-25 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domains IPR003945 (NADH-plastoquinone oxidoreductase, chain 5), IPR000344 (Nematode chemoreceptor, Sra)
3	K08H10.6	K08H10.6	n/a	chrV 9,994,779	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005829 (Sugar transporter, conserved site), IPR005828 (General substrate transporter), IPR008075 (Lipocalin-1 receptor), IPR016196 (MFS general substrate transporter)
4	F58G6.3	F58G6.3	n/a	chrIV 9,653,835	contains similarity to Pfam domain PF04145 Ctr copper transporter family contains similarity to Interpro domains IPR007274 (Ctr copper transporter), IPR001463 (Sodium:alanine symporter)
5	fbxa-54	T12B5.2	n/a	chrIII 957,051	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
6	H41C03.3	H41C03.3	n/a	chrII 5,848,949	contains similarity to Pfam domain PF02485 Core-2/I-Branching enzyme contains similarity to Interpro domain IPR003406 (Glycosyl transferase, family 14)
7	cpin-1	F38E11.3	n/a	chrIV 9,452,280	cpin-1 is orthologous to a mammalian protein variously identified as guanine aminohydrolase (or guanine deaminase, or guanase), cypin, or p51-nedasin.
8	aos-1	C08B6.9	n/a	chrV 10,128,881	aos-1 encodes the C. elegans ortholog of Saccharomyces cerevisiae Aos1p and human SUMO-1 activating enzyme E1 N subunit; by homology, AOS-1 is predicted to form, with a catalytic subunit, UBA-2, a heterodimeric enzyme that activates the ubiquitin-like protein SMO-1/SUMO in preparation for its covalent attachment to target proteins to regulate their subcellular localization and/or stability; in C. elegans, AOS-1 is required for embryonic and larval development, as well as for proper Hox gene regulation; uba-2/aos-1(RNAi) animals that survive embryogenesis show ectopic expression of EGL-5 and ectopic anterior sensory ray formation.
9	R07E4.3	R07E4.3	n/a	chrX 5,953,576	contains similarity to Pfam domain PF02939 UcrQ family contains similarity to Interpro domain IPR004205 (UcrQ)
10	D2023.5	D2023.5	n/a	chrV 11,826,462	contains similarity to Interpro domain IPR001763 (Rhodanese-like)
11	C06E8.5	C06E8.5	n/a	chrIII 7,003,767	contains similarity to Pfam domain PF02886 LBP / BPI / CETP family, C-terminal domain contains similarity to Interpro domain IPR001124 (Lipid-binding serum glycoprotein)
12	nas-27	T23F4.4	n/a	chrII 1,177,703	nas-27 encodes an astacin-like metalloprotease; large-scale expression studies reveal that a nas-27::GFP promoter fusion is expressed in the reproductive system, the vulva, and the hypodermis.
13	K09F6.3	K09F6.3	n/a	chrII 2,258,704	contains similarity to Pfam domains PF02206 (Domain of unknown function) , PF00102 (Protein-tyrosine phosphatase) contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase), IPR003125 (Protein of unknown function WSN)
14	D1054.1	D1054.1	n/a	chrV 10,769,166	contains similarity to Pfam domain PF01734 Patatin-like phospholipase contains similarity to Interpro domains IPR016035 (Acyl transferase/acyl hydrolase/lysophospholipase), IPR002641 (Patatin)
15	dnc-2	C28H8.12	n/a	chrIII 5,925,025	dnc-2 encodes a member of the dynamitin family that affects spindle alignment in polarized cells in early embryos, nuclear movement, spindle morphology, chromosome segregation, and pronuclear migration.
16	C29F7.1	C29F7.1	n/a	chrX 13,413,508	contains similarity to Pfam domains PF02958 (Domain of unknown function (DUF227)) , PF07914 (Protein of unknown function (DUF1679)) contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species), IPR004119 (Protein of unknown function DUF227), IPR015897 (CHK kinase-like)
17	math-22	C46F9.1	n/a	chrII 1,905,746	C. elegans MATH-22 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
18	cul-6	K08E7.7	n/a	chrIV 12,588,438	cul-6 encodes a member of the cullin family that may physically interact with SKR-3.
19	cnb-1	F55C10.1	n/a	chrV 11,376,767	cnb-1 encodes an ortholog of calcineurin B, the regulatory subunit of the protein phosphatase 2B with four EF-hand motifs for calcium binding, that binds TAX-6 (a calcineurin A ortholog) in a calcium-dependent manner; CNB-1 binds calcium, enhances the phosphatase activity of TAX-6 in vitro, promotes transcription of rcn-1, and is required for normal cuticle formation, sperm morphology, and brood size.
20	tomm-7	ZK652.2	n/a	chrIII 7,859,778	C. elegans TOMM-7 protein; contains similarity to Pfam domain PF08038 TOM7 family contains similarity to Interpro domain IPR012621 (Mitochondrial import translocase, subunit Tom7)
21	F39H2.3	F39H2.3	n/a	chrI 8,665,598	contains similarity to Pfam domains PF08669 (Glycine cleavage T-protein C-terminal barrel domain) , PF01571 (Aminomethyltransferase folate-binding domain) contains similarity to Interpro domains IPR006222 (Glycine cleavage T-protein, N-terminal), IPR013977 (Glycine cleavage T-protein, C-terminal barrel)
22	F49E12.10	F49E12.10	n/a	chrII 8,391,583	contains similarity to Pfam domain PF01598 contains similarity to Interpro domain IPR006088 (Sterol desaturase)
23	T09E8.3	T09E8.3	n/a	chrV 13,180,913	contains similarity to Pfam domain PF03311 Cornichon protein contains similarity to Interpro domain IPR003377 (Cornichon)
24	srz-64	Y57G7A.7	n/a	chrII 1,291,002	C. elegans SRZ-64 protein ;
25	H28O16.2	H28O16.2	n/a	chrI 12,649,720	contains similarity to Pfam domain PF00498 FHA domain contains similarity to Interpro domains IPR008984 (SMAD/FHA domain), IPR000253 (Forkhead-associated)
26	B0024.11	B0024.11	n/a	chrV 10,318,482	contains similarity to Pfam domain PF01142 tRNA pseudouridine synthase D (TruD) contains similarity to Interpro domains IPR001656 (tRNA pseudouridine synthase D), IPR011760 (tRNA pseudouridine synthase D, core), IPR017091 (tRNA pseudouridine synthase D, eukaryotic)
27	nspb-4	F38A5.10	n/a	chrIV 6,598,366	C. elegans NSPB-4 protein; contains similarity to Pfam domain PF07312 Protein of unknown function (DUF1459) contains similarity to Interpro domain IPR009924 (Protein of unknown function DUF1459)
28	F39B2.3	F39B2.3	n/a	chrI 14,788,812	contains similarity to Pfam domains PF00107 (Zinc-binding dehydrogenase) , PF08240 (Alcohol dehydrogenase GroES-like domain) contains similarity to Interpro domains IPR013149 (Alcohol dehydrogenase, zinc-binding), IPR011032 (GroES-like), IPR013154 (Alcohol dehydrogenase GroES-like), IPR002085 (Alcohol dehydrogenase superfamily, zinc-containing), IPR016040 (NAD(P)-binding)
29	T08B2.8	T08B2.8	n/a	chrI 6,211,579	contains similarity to Interpro domain IPR012678 (Ribosomal protein L23/L15e, core)
30	inx-15	R12E2.9	n/a	chrI 4,160,065	C. elegans INX-15 protein; contains similarity to Pfam domain PF00876 Innexin contains similarity to Interpro domain IPR000990 (Innexin)
31	nspb-10	C01G12.6	n/a	chrII 14,588,002	C. elegans NSPB-10 protein ;
32	tin-13	DY3.1	n/a	chrI 8,759,490	C. elegans TIN-13 protein; contains similarity to Pfam domain PF02953 Tim10/DDP family zinc finger contains similarity to Interpro domain IPR004217 (Zinc finger, Tim10/DDP-type)
33	C45G9.5	C45G9.5	n/a	chrIII 5,049,097
34	elt-2	C33D3.1	n/a	chrX 10,482,266	elt-2 encodes a GATA-type transcription factor most similar to the vertebrate GATA4-6 transcription factors required for cardiac and endoderm development (OMIM:601656, 600576); in C. elegans, ELT-2 is required redundantly with ELT-7 for initiating and maintaining terminal differentiation of the intestine; ELT-2 is expressed solely in the intestine, beginning embryonically at the 2E-cell stage and continuing in all intestinal cells throughout the life of the animal; in the regulatory hierarchy controlling endoderm development, ELT-2 lies downstream of the maternal regulators SKN-1 and POP-1 and the embryonic GATA factors MED-1/-2, and END-1/-3; in turn, ELT-2, along with ELT-7, likely regulates transcription of a number of intestine-specific terminal differentiation genes such as ges-1, ifb-2, pha-4, and the stress-induced mtl-2; ELT-2 also positively autoregulates, presumably to ensure maintenance of intestinal differentiation
35	ulp-2	Y38A8.3	n/a	chrII 4,957,746	C. elegans ULP-2 protein; contains similarity to Pfam domain PF02902 Ulp1 protease family, C-terminal catalytic domain contains similarity to Interpro domain IPR003653 (Peptidase C48, SUMO/Sentrin/Ubl1)
36	Y54G11A.2	Y54G11A.2	n/a	chrII 14,253,902	contains similarity to Pfam domain PF05670 Domain of unknown function (DUF814) contains similarity to Interpro domain IPR008532 (Protein of unknown function DUF814)
37	K07G5.5	K07G5.5	n/a	chrI 7,171,105	contains similarity to Pfam domain PF01545 Cation efflux family contains similarity to Interpro domain IPR002524 (Cation efflux protein)
38	pxn-2	K09C8.5	n/a	chrX 10,975,651	C. elegans PXN-2 protein; contains similarity to Pfam domains PF00047 (Immunoglobulin domain) (2), PF00560 (Leucine Rich Repeat) (3), PF01462 (Leucine rich repeat N-terminal domain) , PF07679 (Immunoglobulin I-set domain) (2), PF03098 (Animal haem peroxidase) contains similarity to Interpro domains IPR003598 (Immunoglobulin subtype 2), IPR000483 (Cysteine-rich flanking region, C-terminal), IPR001611 (Leucine-rich repeat), IPR013098 (Immunoglobulin I-set), IPR010255 (Haem peroxidase), IPR003596 (Immunoglobulin V-set, subgroup), IPR013783 (Immunoglobulin-like fold), IPR003591 (Leucine-rich repeat, typical subtype), IPR007110 (Immunoglobulin-like), IPR002007 (Haem peroxidase, animal), IPR000372 (Leucine-rich repeat, cysteine-rich flanking region, N-terminal), IPR003599 (Immunoglobulin subtype), IPR013151 (Immunoglobulin)
39	C33D3.3	C33D3.3	n/a	chrX 10,485,911	contains similarity to Interpro domains IPR000679 (Zinc finger, GATA-type), IPR013088 (Zinc finger, NHR/GATA-type), IPR011011 (Zinc finger, FYVE/PHD-type)
40	ZC504.3	ZC504.3	n/a	chrX 10,418,158	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR008351 (JNK MAP kinase), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
41	ZK795.3	ZK795.3	n/a	chrIV 12,559,996	contains similarity to Pfam domain PF04427 Brix domain contains similarity to Interpro domain IPR007109 (Brix)
42	cln-3.1	F07B10.1	n/a	chrV 11,264,600	cln-3.1 encodes a predicted transmembrane protein that comprises one of three C. elegans homologs of human CLN3, (OMIM:607042, mutations are associated with Batten disease (also known as juvenile neuronal ceroid lipofuscinosis), a recessively inherited childhood neurodegenerative lysosomal storage disease); as loss of cln-3.1 activity via deletion mutation results in no obvious abnormalities, the precise role of cln-3.1 in C. elegans development and/or behavior is not yet known.
43	arx-5	Y37D8A.1	n/a	chrIII 12,817,350	arx-5 encodes the C. elegans ortholog of the p21Arc subunit of the actin-related protein (Arp) 2/3 complex.
44	F53C11.3	F53C11.3	n/a	chrV 13,783,418	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR000507 (Adrenergic receptor, beta 1), IPR002424 (Insect alcohol dehydrogenase family), IPR003560 (2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
45	rap-3	C08F8.7	n/a	chrIV 11,177,654	C. elegans RAP-3 protein; contains similarity to Pfam domains PF00071 (Ras family) , PF08477 (Miro-like protein) contains similarity to Interpro domains IPR002041 (Ran GTPase), IPR003577 (Ras small GTPase, Ras type), IPR013684 (Miro-like), IPR003578 (Ras small GTPase, Rho type), IPR005225 (Small GTP-binding protein), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR006688 (ADP-ribosylation factor), IPR013753 (Ras), IPR006689 (ARF/SAR superfamily)
46	ddb-1	M18.5	n/a	chrIV 12,117,957	M18.5 is orthologous to the human gene DAMAGE-SPECIFIC DNA BINDING PROTEIN 1 (127KD) (DDB1; OMIM:600045), which when mutated leads to disease.
47	cid-1	K10D2.3	n/a	chrIII 5,177,184	cid-1 (also known as pup-1) encodes a template-independent poly(U) polymerase with 3'' end RNA substrates, orthologous to human ZCCHC6 and ZCCHC11, and paralogous to PUP-2; CID-1 prevents larvae from growing to adulthood in media containing hydroxyurea (HU, a drug that stalls replication forks) and represses HSP-4 expression; CID-1 is required for gonadogenesis, embryonic and vulval development, normally rapid growth, and normally short lifespan; CID-1, like HSP-4, is expressed in postmitotic intestinal cells; by orthology with Cid1p in fission yeast, CID-1 is predicted to act in a DNA synthesis-to-mitosis checkpoint; in cid-1(rf35::Tc4) mutants or cid-1(RNAi) animals grow from L1 larvae to adulthood despite the presence of HU, are abnormally resistant to lethal heat shock, overexpress hsp-4::GFP, have protruding vulvae, have abnormally short and thick gonads with fewer germ cells than normal, produce disorganized embryos, grow slowly, and have abnormally long lifespans; CID-1 and its eukaryotic homologs are distantly related to the GLD-2 family of poly(A) polymerases.
48	K02G10.5	K02G10.5	n/a	chrX 4,689,524	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF03137 (Organic Anion Transporter Polypeptide (OATP) family) contains similarity to Interpro domains IPR004156 (Organic anion transporter polypeptide OATP), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
49	C35A5.3	C35A5.3	n/a	chrV 10,500,362	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
50	gro-1	ZC395.6	n/a	chrIII 5,266,087	C. elegans GRO-1 protein; contains similarity to Pfam domain PF01715 IPP transferase contains similarity to Interpro domains IPR003604 (Zinc finger, U1-type), IPR002627 (tRNA isopentenyltransferase), IPR003593 (AAA+ ATPase, core), IPR011593 (Isopentenyl transferase-like), IPR007087 (Zinc finger, C2H2-type)