UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	fbxb-51	K05F6.3	0	chrII 1,552,094	C. elegans FBXB-51 protein; contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
2	sdz-31	T11A5.5	n/a	chrV 9,880,568	C. elegans SDZ-31 protein; contains similarity to Interpro domains IPR001376 (Gliadin, alpha/beta), IPR000896 (Hemocyanin, copper-containing)
3	fbxb-40	M01D1.9	4e-21	chrII 1,049,413	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
4	cdh-3	ZK112.7	n/a	chrIII 7,747,815	cdh-3 encodes a member of the cadherin superfamily that affects morphogenesis of tail epithelia and excretory function; expressed predominantly in developing epithelial cells, and also expressed in the AC, excretory cell, various neurons, and vulval cells during different stages of development.
5	ZC204.2	ZC204.2	n/a	chrII 1,664,783	contains similarity to Pfam domain PF00046 Homeobox domain contains similarity to Interpro domains IPR012287 (Homeodomain-related), IPR001356 (Homeobox), IPR009057 (Homeodomain-like)
6	nac-2	R107.1	n/a	chrIII 9,040,048	nac-2 encodes a high affinity sodium-coupled citrate transporter that is orthologous to the mammalian citrate transporter NaCT and is one of four C. elegans proteins related to Drosophila Indy; when expressed in a heterologous system, NAC-2 exhibits high affinity sodium/citrate and sodium/succinate cotransporter activity, although the transport rate for citrate is much higher than that for succinate; nac-2::gfp reporter fusions are expressed in the intestine, from early larval stages through adulthood; the effects of nac-2(RNAi) are variable, with reports of a 19% increase in lifespan accompanied by decreased body size and fat content in affected animals and reports of no apparent decrease in average lifespan.
7	F58E1.4	F58E1.4	n/a	chrII 1,680,715	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
8	his-5	F45F2.3	n/a	chrV 8,535,370	his-5 encodes an H4 histone.
9	ZK1055.4	ZK1055.4	n/a	chrV 6,586,468	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
10	srg-3	C18F10.6	n/a	chrIII 6,269,673	C. elegans SRG-3 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
11	C31E10.6	C31E10.6	n/a	chrX 13,997,720	contains similarity to Saccharomyces cerevisiae Mlp proteins restrict telomere length by influencing the Rif1-Tel1 pathway of telomerase regulation; also involved in the translocation of macromolecules between the nucleoplasm and the NPC; SGD:YKR095W
12	srj-49	T03D3.12	n/a	chrV 2,847,294	C. elegans SRJ-49 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
13	hil-8	T05E8.2	n/a	chrI 5,467,787	C. elegans HIL-8 protein; contains similarity to Interpro domain IPR005818 (Histone H1/H5)
14	fbxb-9	C08F8.5	n/a	chrIV 11,161,021	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
15	srg-37	K04C1.1	n/a	chrX 14,234,536	C. elegans SRG-37 protein; contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
16	srj-57	T03D3.14	n/a	chrV 2,854,982	C. elegans SRJ-57 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
17	ugt-32	F47C10.6	n/a	chrV 3,842,918	C. elegans UGT-32 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
18	Y39A1A.7	Y39A1A.7	n/a	chrIII 10,619,501	contains similarity to Sus scrofa Lymphocyte antigen 64-like protein.; TR:Q7YRL4
19	F28C6.9	F28C6.9	n/a	chrII 8,609,707	contains similarity to Homo sapiens Hypothetical protein KIAA0562; ENSEMBL:ENSP00000263739
20	sri-1	F36G9.8	n/a	chrV 15,966,916	C. elegans SRI-1 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR002208 (SecY protein)
21	F28C6.1	F28C6.1	n/a	chrII 8,591,963	F28C6.1 encodes an AP-2-like transcription factor that is ~60% identical to that of F28C6.2 which lies immediately adjacent to F28C6.1 on chromosome II; loss of F28C6.1 activity via large-scale RNAi experiments results in embryonic and larval lethality.
22	T03D8.7	T03D8.7	n/a	chrV 20,811,735	contains similarity to Homo sapiens Uncharacterized protein ENSP00000381489; ENSEMBL:ENSP00000335483
23	fbxb-5	F45C12.14	n/a	chrII 1,721,873	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
24	Y116A8B.4	Y116A8B.4	n/a	chrIV 17,224,339	contains similarity to Clostridium acetobutylicum Predicted membrane protein.; TR:Q97KC4
25	nhr-152	C12D5.2	n/a	chrV 7,687,313	C. elegans NHR-152 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
26	F14H8.5	F14H8.5	n/a	chrV 15,021,516	contains similarity to Bacillus cereus Hypothetical membrane spanning protein.; TR:Q812W2
27	F17H10.4	F17H10.4	n/a	chrX 13,126,169	contains similarity to Macaca fascicularis Cytochrome oxidase subunit VIII.; TR:Q8SPI5
28	knl-2	K06A5.4	n/a	chrI 6,462,350	C. elegans KNL-2 protein; contains similarity to Pfam domain PF09133 SANTA (SANT Associated) contains similarity to Interpro domain IPR015216 (SANT associated)
29	F46F3.3	F46F3.3	n/a	chrV 11,668,418	contains similarity to Dictyostelium discoideum Hypothetical protein.; TR:Q86J27
30	C44C10.7	C44C10.7	n/a	chrX 11,687,559	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
31	C53D6.4	C53D6.4	n/a	chrIV 9,020,038	contains similarity to Pfam domain PF00085 Thioredoxin contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR013766 (Thioredoxin domain)
32	srt-17	F48G7.6	n/a	chrV 624,474	C. elegans SRT-17 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
33	mab-7	ZC13.4	n/a	chrX 895,155	mab-7 encodes a protein with a hydrophobic type II transmembrane region at the N-terminus, an EGF-like motif, a ShKT motif and a long C-terminus; mab-7 is involved in morphogenesis of the male tail, specifically affecting the structural cells, neuronal processes and the hypodermal sheath of the sensory rays, as such, it affects mating in males; a mab-7 promoter-gfp construct is expressed in hypodermis, body seam, ray structural cells, and several neurons in the head and tail region.
34	hnd-1	C44C10.8	n/a	chrX 11,685,111	hnd-1 encodes a Hand bHLH transcription factor required for normal viability, gonadogenesis, and posterior body morphology; HND-1 is required for the formation of both somatic gonadal precursors and primordial germ cells, but not for later gonadogenesis; HND-1 is expressed embryogenesis in embryonic mesodermal precursor cells generating (mostly) body wall muscle, in somatic gonad precursor cells, and in some unidentified head cells; the primary defect in hnd-1 mutants may be, nonautonomously, in mesodermal precursor cells; somatic gonad precursor cells are normally generated in hnd-1 mutants, but not maintained.
35	K02H11.4	K02H11.4	n/a	chrV 1,529,803	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008167 (Protein of unknown function DUF23, C-terminal), IPR008166 (Protein of unknown function DUF23)
36	kin-29	F58H12.1	n/a	chrX 2,848,198	kin-29 encodes a serine/threonine kinase with significant homology in the kinase domain to the AMP-activated protein kinase (AMPK) and SNF1 kinases; the AMP-kinase cascade is activated by cellular stresses that deplete ATP; AMP-kinase is believed to protect the mammalian cell by 'switching off' ATP-consuming pathways like fatty acid synthesis, by phosphorylating key regulatory enzymes, and switching on alternative pathways for ATP generation; kin-29 is involved in regulating the expression of chemosensory receptors and entry into the daur pathway; kin-29 also affects body size via interaction with the Sma/Mab pathway and lifespan, with mutants exhibiting a smaller body size and increased life span; a functional KIN-29-GFP fusion protein is expressed in sensory neurons and many other cell types, and localizes to the cytoplasm; under conditions of cellular stress like heat shock and starvation, KIN-29-GFP translocates to the nucleus.
37	ZK1307.9	ZK1307.9	n/a	chrII 9,650,113	contains similarity to Pfam domain PF04502 Family of unknown function (DUF572) contains similarity to Interpro domain IPR007590 (Protein of unknown function DUF572)
38	F38E1.6	F38E1.6	n/a	chrV 8,360,585	contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
39	K03A11.1	K03A11.1	n/a	chrX 13,053,489	contains similarity to Interpro domain IPR001130 (Deoxyribonuclease, TatD-related)
40	B0041.3	B0041.3	n/a	chrI 4,645,153	contains similarity to Pfam domain PF01476 LysM domain contains similarity to Interpro domain IPR002482 (Peptidoglycan-binding LysM)
41	F55H12.3	F55H12.3	n/a	chrI 8,884,703	contains similarity to Pfam domains PF00008 (EGF-like domain) (5), PF07645 (Calcium binding EGF domain) , PF07699 (GCC2 and GCC3) (3), PF07974 (EGF-like domain) (5), PF00057 (Low-density lipoprotein receptor domain class A) , PF02494 (HYR domain) , PF00084 (Sushi domain (SCR repeat)) (2)contains similarity to Interpro domains IPR000483 (Cysteine-rich flanking region, C-terminal), IPR000742 (EGF-like, type 3), IPR003410 (Hyalin), IPR000436 (Sushi/SCR/CCP), IPR006209 (EGF-like), IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR002172 (Low density lipoprotein-receptor, class A, cysteine-rich), IPR011641 (GCC2 and GCC3), IPR016187 (C-type lectin fold), IPR001881 (EGF-like calcium-binding), IPR016060 (Complement control module), IPR009030 (Growth factor, receptor), IPR016186 (C-type lectin-like), IPR013032 (EGF-like region, conserved site), IPR001304 (C-type lectin), IPR013111 (EGF, extracellular), IPR013091 (EGF calcium-binding), IPR008985 (Concanavalin A-like lectin/glucanase)
42	srw-127	C33G8.1	n/a	chrV 7,013,646	C. elegans SRW-127 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
43	Y52B11A.7	Y52B11A.7	n/a	chrI 11,022,105	contains similarity to Pfam domains PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) , PF02932 (Neurotransmitter-gated ion-channel transmembrane region) contains similarity to Interpro domains IPR011050 (Pectin lyase fold/virulence factor), IPR002394 (Nicotinic acetylcholine receptor, N-terminal), IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding), IPR006029 (Neurotransmitter-gated ion-channel transmembrane region)
44	R03G8.4	R03G8.4	n/a	chrX 13,102,677	contains similarity to Pfam domain PF01433 Peptidase family M1 contains similarity to Interpro domains IPR014782 (Peptidase M1, membrane alanine aminopeptidase, N-terminal), IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR001930 (Peptidase M1, membrane alanine aminopeptidase)
45	K09C4.2	K09C4.2	n/a	chrX 3,297,833
46	arl-6	C38D4.8	n/a	chrIII 4,814,024	arl-6 encodes an ADP-Ribosylation factor-Like member of the Ras superfamily of small GTP-binding proteins and is a predicted homolog of the human ARL6 gene, identified as the gene that underlies Bardet-Biedl syndrome type 3; GFP-tagged ARL-6 undergoes intraflagellar transport (IFT) in the ciliary axoneme, implicating ARL-6 in ciliary transport; arl-6 is expressed in amphid and phasmid ciliated sensory neurons.
47	C32B5.9	C32B5.9	n/a	chrII 955,198
48	srw-97	ZC204.15	n/a	chrII 1,668,270	C. elegans SRW-97 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
49	W05H9.2	W05H9.2	n/a	chrX 6,269,009
50	R13.3	R13.3	n/a	chrIV 10,830,875	contains similarity to Pfam domain PF01062 Bestrophin contains similarity to Interpro domain IPR000615 (Bestrophin)