UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	K04G2.10	K04G2.10	2e-167	chrI 8,059,153	contains similarity to Homo sapiens Meiosis-specific nuclear structural protein 1; ENSEMBL:ENSP00000260453
2	sra-25	T26E3.9	n/a	chrI 12,687,150	C. elegans SRA-25 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domains IPR003945 (NADH-plastoquinone oxidoreductase, chain 5), IPR000344 (Nematode chemoreceptor, Sra)
3	kbp-5	C34B2.2	n/a	chrI 10,687,701	C. elegans KBP-5 protein ;
4	cks-1	C09G4.3	n/a	chrIV 8,514,308	A homolog of Cks/Suc1, a highly conserved member of the eukaryotic cell cycle machinery that affects both meiosis and mitosis and has a role in the inactivation of the M-phase promoting factor (MPF) during early embryogenesis.
5	C02B10.2	C02B10.2	n/a	chrIV 5,090,651	contains similarity to Homo sapiens SNARE-associated protein Snapin; ENSEMBL:ENSP00000357674
6	C13F10.2	C13F10.2	n/a	chrV 7,221,750	contains similarity to Drosophila melanogaster Flybase gene name is CG10681-PA;; FLYBASE:CG10681
7	F19B10.2	F19B10.2	n/a	chrII 3,676,170
8	T05B11.4	T05B11.4	n/a	chrV 7,753,022	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
9	F54F7.6	F54F7.6	n/a	chrX 11,866,107	contains similarity to Homo sapiens Golgi autoantigen, golgin subfamily B member 1; ENSEMBL:ENSP00000315938
10	nhr-263	F10G2.9	n/a	chrV 7,341,043	C. elegans NHR-263 protein; contains similarity to Pfam domain PF00104 Ligand-binding domain of nuclear hormone receptor contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
11	T04D3.5	T04D3.5	n/a	chrI 13,330,023
12	F40G9.7	F40G9.7	n/a	chrIII 165,986
13	meg-2	K02B9.2	n/a	chrX 13,924,518	meg-2 encodes a novel protein that localizes exclusively to P granules; originally identified by microarray analyses of germline-enriched transcripts, loss of meg-2 activity by itself results in no obvious abnormalities, but loss of meg-2 activity in meg-1 mutant animals indicates that meg-1 and meg-2 likely have redundant functions in germline development; meg-2 may also function redundantly with mes-1; meg-2 expression in the proximal germline is positively regulated by MPK-1, the C. elegans MAP kinase ortholog; a GFP::MEG-2 fusion protein localizes exclusively to P granules in the embryonic germ cell lineage.
14	C35D10.13	C35D10.13	n/a	chrIII 4,877,976
15	B0304.2	B0304.2	n/a	chrII 4,524,073
16	lrr-1	F33G12.4	n/a	chrII 5,035,345	F33G12.4 encodes a leucine rich repeat-containing protein; loss of F33G12.4 activity via large-scale RNAi indicates that F33G12.4 is essential for embryonic and larval development.
17	sdz-37	ZK673.10	n/a	chrII 10,465,005	C. elegans SDZ-37 protein ;
18	K03H1.7	K03H1.7	n/a	chrIII 9,947,654	contains similarity to Saccharomyces cerevisiae major low affinity 55 kDa Centromere/microtubule binding protein; SGD:YLR175W
19	F28F8.5	F28F8.5	n/a	chrV 15,574,751	contains similarity to Methanosarcina mazei Glutamyl-tRNA(Gln) amidotransferase subunit E (EC 6.3.5.-) (Glu-ADTssubunit E).; SW:GATE_METMA
20	F37D6.4	F37D6.4	n/a	chrI 10,488,809	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
21	pcn-1	W03D2.4	n/a	chrIV 4,048,721	pcn-1 encodes the C. elegans ortholog of proliferating cell nuclear antigen (PCNA), an acidic protein that is an essential component of the DNA replication and repair machinery and serves as a processivity factor for DNA polymerase delta; PCN-1 is required for early embryogenesis and for proper germ-line development, and directly interacts with CKI-2, a cyclin-dependent kinase inhibitor homolog that may be required for cell cycle progression during embryogenesis, and with ATL-1/PI3K, KIN-20, MRT-2/RAD1, and RFC-1, proteins that all play a role in the DNA damage checkpoint pathway; PCN-1 is highly expressed in ovaries and developing embryos.
22	W06D11.1	W06D11.1	n/a	chrX 12,294,462
23	F10A3.1	F10A3.1	n/a	chrV 16,140,754	F10A3.1 encodes a claudin homolog that may be required for normal cohesion of apical junctions in epithelia; F10A3.1 is worm-specific, with obvious homologs only in C. elegans; F10A3.1 has no obvious function in mass RNAi assays; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water.
24	C17H11.4	C17H11.4	n/a	chrX 8,181,277	contains similarity to Drosophila melanogaster Flybase gene name is ari-1-PC;; FLYBASE:CG5659
25	C48B6.3	C48B6.3	n/a	chrI 6,915,508	contains similarity to Homo sapiens UPF0472 protein C16orf72; ENSEMBL:ENSP00000331720
26	R10E4.6	R10E4.6	n/a	chrIII 4,294,138
27	lsm-7	ZK593.7	n/a	chrIV 10,933,821	C. elegans LSM-7 protein; contains similarity to Pfam domain PF01423 LSM domain contains similarity to Interpro domains IPR001163 (Like-Sm ribonucleoprotein, core), IPR006649 (Like-Sm ribonucleoprotein, eukaryotic and archaea-type, core), IPR010920 (Like-Sm ribonucleoprotein-related, core), IPR017132 (U6 snRNA-associated Sm-like protein LSm7)
28	F01F1.11	F01F1.11	n/a	chrIII 5,870,989
29	F14H3.3	F14H3.3	n/a	chrV 16,052,681	contains similarity to Homo sapiens Trichohyalin; ENSEMBL:ENSP00000357794
30	F32D1.6	F32D1.6	n/a	chrV 4,374,245
31	C41D11.5	C41D11.5	n/a	chrI 4,450,433
32	C25A1.1	C25A1.1	n/a	chrI 10,162,948	contains similarity to Danio rerio Novel protein (Zgc:65774).; TR:Q1LX81
33	F28C6.2	F28C6.2	n/a	chrII 8,595,158	F28C6.2 encodes an AP-2-like transcription factor that is ~60% identical to that of F28C6.1, which lies adjacent to F28C6.1 on chromosome II; loss of F28C6.2 activity via large-scale RNAi results in some embryonic lethality and low levels of larval arrest, body morphology defects, and uncoordinated locomotion.
34	C48B6.9	C48B6.9	n/a	chrI 6,924,938	contains similarity to Interpro domain IPR000366 (Fungal pheromone mating factor STE2 GPCR)
35	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
36	R53.6	R53.6	n/a	chrII 9,969,060	contains similarity to Pfam domain PF03651 Partner of SLD five, PSF1 contains similarity to Interpro domain IPR005339 (GINS complex, Psf1 component)
37	C42C1.8	C42C1.8	n/a	chrIV 12,292,136	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
38	T20D3.8	T20D3.8	n/a	chrIV 9,342,540	contains similarity to Pfam domain PF06432 Phosphatidylinositol N-acetylglucosaminyltransferase contains similarity to Interpro domain IPR009450 (Phosphatidylinositol N-acetylglucosaminyltransferase)
39	rfc-3	C39E9.13	n/a	chrIV 13,096,350	C. elegans RFC-3 protein; contains similarity to Interpro domains IPR008921 (DNA polymerase III clamp loader subunit, C-terminal), IPR003593 (AAA+ ATPase, core)
40	try-1	ZK546.15	n/a	chrII 4,948,807	C. elegans TRY-1 protein; contains similarity to Pfam domain PF00089 Trypsin contains similarity to Interpro domains IPR001314 (Peptidase S1A, chymotrypsin), IPR001254 (Peptidase S1 and S6, chymotrypsin/Hap), IPR009003 (Peptidase, trypsin-like serine and cysteine), IPR008256 (Peptidase S1B, glutamyl endopeptidase I)
41	K09E3.7	K09E3.7	n/a	chrX 17,132,904	contains similarity to Homo sapiens Conserved hypothetical protein; HI:HIT000048720
42	F31B9.3	F31B9.3	n/a	chrX 15,924,034	contains similarity to Homo sapiens Similar to polymerase (RNA) III; ENSEMBL:ENSP00000334758
43	kbp-1	R13F6.1	n/a	chrIII 6,869,906	C. elegans KBP-1 protein ;
44	F15A4.2	F15A4.2	n/a	chrII 12,463,181	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
45	Y5F2A.4	Y5F2A.4	n/a	chrIV 11,077,311	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR013087 (Zinc finger, C2H2-type/integrase, DNA-binding), IPR007087 (Zinc finger, C2H2-type)
46	hop-1	C18E3.8	n/a	chrI 4,209,468	hop-1 encodes one of three C. elegans presenilins (the other two presenilins are encoded by sel-12 and spe-4); originally identified on the basis of its sequence similarity to SEL-12 and the human PS1 and PS2 presenilins, HOP-1 has been shown to function redundantly with SEL-12 in embryonic, larval, and germline development and thus, to likely function by regulating LIN-12/GLP-1 signaling; in addition, hop-1 can functionally substitute for sel-12 by rescuing the egg-laying and vulval development defects of sel-12 mutants; hop-1 transcription appears to be regulated, at least in part, by the C. elegans spr genes, some of which encode orthologs of the mammalian CoREST repressor complex.
47	T22C8.4	T22C8.4	n/a	chrII 8,623,075	contains similarity to Interpro domains IPR003656 (Zinc finger, BED-type predicted), IPR007087 (Zinc finger, C2H2-type)
48	mxl-1	T19B10.11	n/a	chrV 11,245,345	mxl-1 encodes a basic helix-loop-helix protein similar to the vertebrate MAX transcriptional regulators; in vitro, MXL-1 can heterodimerize, and bind an E-box DNA sequence, with MDL-1, a C. elegans MAD-like bHLH protein; mxl-1::gfp reporter fusions are expressed in the posterior intestine and in head and tail neurons.
49	F02H6.2	F02H6.2	n/a	chrIV 14,197,604	contains similarity to Trichomonas vaginalis G3 Putative uncharacterized protein.; TR:A2F8N8
50	W03C9.2	W03C9.2	n/a	chrII 11,963,758	contains similarity to Schizosaccharomyces pombe Transcription elongation factor S-II (TFIIS).; SW:TFS2_SCHPO