UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	lim-6	K03E6.1	2e-142	chrX 1,076,785	lim-6 encodes a LIM class homeodomain protein that contains two Zinc-finger-like LIM domains N-terminal to a predicted DNA-binding homeodomain; LIM-6 is predicted to function as a transcription factor whose activity is required for regulating uterine morphogenesis and specific aspects of terminal neuronal differentiation, including normal axonal morphology, full expression of UNC-25/glutamic acid decarboxylase in select GABAergic neurons, and repression of sensory receptor gene expression in the ASEL chemosensory neuron; LIM-6 is expressed in a group of nine chemosensory-, inter-, and motorneurons, uterine toroid cells, spermathecal junction cells, and the binucleate excretory gland cell.
2	C44C10.3	C44C10.3	n/a	chrX 11,703,337	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005828 (General substrate transporter), IPR016196 (MFS general substrate transporter)
3	haf-2	F43E2.4	n/a	chrII 7,354,944	haf-2 encodes a predicted transmembrane protein of the ATP-binding cassette (ABC) transporter superfamily; by homology, HAF-2 is proposed to function in ATP-dependent transport of molecules across plasma and intracellular membranes; however, as loss of HAF-2 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of HAF-2 in C. elegans development and/or behavior is not yet known.
4	F25B5.5	F25B5.5	n/a	chrIII 5,944,924	contains similarity to Pfam domains PF00919 (Uncharacterized protein family UPF0004) , PF04055 (Radical SAM superfamily) , PF01938 (TRAM domain) contains similarity to Interpro domains IPR005839 (Protein of unknown function UPF0004), IPR013848 (Protein of unknown function UPF0004, N-terminal), IPR007197 (Radical SAM), IPR006638 (Elongator protein 3/MiaB/NifB), IPR002792 (Deoxyribonuclease/rho motif-related TRAM)
5	F10C2.5	F10C2.5	n/a	chrV 12,047,001	contains similarity to Pfam domain PF01532 Glycosyl hydrolase family 47 contains similarity to Interpro domains IPR010916 (TonB box, conserved site), IPR001382 (Glycoside hydrolase, family 47)
6	srt-7	C50H11.4	n/a	chrV 3,082,398	C. elegans SRT-7 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR000408 (Regulator of chromosome condensation, RCC1)
7	C04G6.4	C04G6.4	n/a	chrII 5,082,452	contains similarity to Interpro domain IPR000694 (Proline-rich region)
8	scl-27	ZK6.3	n/a	chrV 400,930	C. elegans SCL-27 protein; contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR001283 (Allergen V5/Tpx-1 related)
9	C14B9.8	C14B9.8	n/a	chrIII 8,142,045	C14B9.8 is orthologous to the human gene PHOSPHORYLASE KINASE, LIVER, ALPHA-2 SUBUNIT (PHKA2; OMIM:306000), which when mutated leads to liver glycogenosis.
10	sru-8	R07B5.7	n/a	chrV 9,844,985	C. elegans SRU-8 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domains IPR001463 (Sodium:alanine symporter), IPR003839 (Protein of unknown function DUF215)
11	K03B4.1	K03B4.1	n/a	chrV 4,690,455
12	srh-211	D1065.5	n/a	chrV 4,078,922	C. elegans SRH-211 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
13	C09G5.2	C09G5.2	n/a	chrII 10,708,359	C09G5.2 encodes an ortholog of S. cerevisiae DPH2/YKL191W and human DPH2L2 (OMIM:603456); C09G5.2 is a putative protein component of diphtamide synthesis; C09G5.2 has no obvious function in mass RNAi assays.
14	gpa-11	C16A11.1	n/a	chrII 4,254,160	gpa-11 encodes a member of the G protein alpha subunit family of heterotrimeric GTPases; it is expressed in ADL and ASH amphid neurons.
15	his-32	F17E9.10	n/a	chrIV 8,334,513	his-32 encodes an H3 histone; by homology, HIS-32 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-32 is a replication-dependent histone locus that resides in the HIS5 cluster on chromosome IV.
16	clec-115	C49A1.6	n/a	chrI 14,246,758	C. elegans CLEC-115 protein; contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domains IPR006583 (CW), IPR016187 (C-type lectin fold), IPR001304 (C-type lectin)
17	nlp-16	T13A10.5	n/a	chrIV 6,257,461	nlp-16 encodes a predicted neuropeptide that does not belong to a multigene family in C. elegans and is not clearly related to well-characterized neuropeptides; the peptide encoded by nlp-16 has been isolated from Ascaris suum.
18	F41G4.5	F41G4.5	n/a	chrX 16,831,782
19	mlt-4	ZC15.7	n/a	chrV 20,280,792	mlt-4 encodes a homolog of human INVS (inversin, OMIM:243305; mutated in nephronophthisis) that has no function in mass RNAi assays.
20	C26B2.7	C26B2.7	n/a	chrIV 8,016,527
21	str-40	C50H11.12	n/a	chrV 3,068,667	C. elegans STR-40 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
22	kin-4	C10C6.1	n/a	chrIV 11,441,819	C. elegans KIN-4 protein; contains similarity to Pfam domains PF08926 (Domain of unknown function (DUF1908)) , PF00595 (PDZ domain (Also known as DHR or GLGF)) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR015022 (Region of unknown function DUF1908), IPR000719 (Protein kinase, core), IPR001478 (PDZ/DHR/GLGF), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR000961 (Protein kinase, C-terminal)
23	fpn-1.2	R09B5.4	n/a	chrV 1,463,421	R09B5.4 is orthologous to the human gene HYPOTHETICAL PROTEIN (SLC11A3; OMIM:604653), which when mutated leads to disease.
24	C15C7.1	C15C7.1	n/a	chrX 3,165,079	contains similarity to Pfam domain PF05739 SNARE domain contains similarity to Interpro domains IPR000727 (Target SNARE coiled-coil region), IPR001388 (Synaptobrevin), IPR006012 (Syntaxin/epimorphin, conserved site)
25	Y40B10B.1	Y40B10B.1	n/a	chrV 1,960,770	contains similarity to Pfam domain PF03762 Vitelline membrane outer layer protein I (VOMI) contains similarity to Interpro domain IPR005515 (Vitelline membrane outer layer protein I (VOMI))
26	F21G4.5	F21G4.5	n/a	chrX 9,906,914	contains similarity to Interpro domain IPR007087 (Zn-finger, C2H2 type)
27	F25B4.7	F25B4.7	n/a	chrV 5,686,614	contains similarity to Pfam domain PF00153 Mitochondrial carrier protein contains similarity to Interpro domains IPR002067 (Mitochondrial carrier protein), IPR002030 (Mitochondrial brown fat uncoupling protein), IPR001993 (Mitochondrial substrate carrier), IPR002113 (Adenine nucleotide translocator 1)
28	B0250.5	B0250.5	n/a	chrV 20,491,021	contains similarity to Pfam domain PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase contains similarity to Interpro domains IPR006115 (6-phosphogluconate dehydrogenase, NAD-binding), IPR013328 (Dehydrogenase, multihelical), IPR015815 (3-hydroxyacid dehydrogenase/reductase), IPR011548 (3-hydroxyisobutyrate dehydrogenase), IPR006183 (6-phosphogluconate dehydrogenase), IPR016040 (NAD(P)-binding), IPR002204 (3-hydroxyisobutyrate dehydrogenase-related, conserved site)
29	T24H10.1	T24H10.1	n/a	chrII 9,099,835	contains similarity to Pfam domains PF07500 (Transcription factor S-II (TFIIS), central domain) , PF08711 (Transcription elongation factor S-II protein N terminal) , PF01096 (Transcription factor S-II (TFIIS)) contains similarity to Interpro domains IPR001222 (Zinc finger, TFIIS-type), IPR003618 (Transcription elongation factor S-II, central region), IPR014754 (Transcription elongation factor, TFIIS, N-terminal, fungal-type), IPR003617 (Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type), IPR014765 (Transcription elongation factor, TFIIS/CRSP70, N-terminal), IPR016492 (Transcription elongation factor, IIS), IPR006289 (Transcription elongation factor, TFIIS), IPR010990 (Transcription elongation factor, TFIIS/elongin A/CRSP70, N-terminal)
30	T11F8.2	T11F8.2	n/a	chrIV 5,477,982
31	grsp-3	C34D4.11	n/a	chrIV 7,131,263	C. elegans GRSP-3 protein; contains similarity to Interpro domains IPR005405 (Potassium channel, voltage dependent, Kv3.4), IPR002952 (Eggshell protein), IPR003991 (Pertactin virulence factor, C-terminal), IPR000817 (Prion protein), IPR001951 (Histone H4)
32	T26A5.8	T26A5.8	n/a	chrIII 6,462,478	contains similarity to Pfam domain PF00808 Histone-like transcription factor (CBF/NF-Y) and archaeal histone contains similarity to Interpro domains IPR009072 (Histone-fold), IPR003958 (Transcription factor CBF/NF-Y/archaeal histone)
33	T01D3.2	T01D3.2	n/a	chrV 13,706,650	contains similarity to Pfam domain PF00989 PAS fold contains similarity to Interpro domains IPR001092 (Basic helix-loop-helix dimerisation region bHLH), IPR013767 (PAS fold), IPR000014 (PAS), IPR011598 (Helix-loop-helix DNA-binding), IPR001067 (Nuclear translocator)
34	F13H8.3	F13H8.3	n/a	chrII 6,264,731	contains similarity to Pfam domain PF01156 Inosine-uridine preferring nucleoside hydrolase contains similarity to Interpro domain IPR001910 (Inosine/uridine-preferring nucleoside hydrolase)
35	glr-8	F22A3.3	n/a	chrX 6,508,340	glr-8 encodes a highly divergent putative ionotropic glutamate receptor subunit, unclassifiable as NMDA or non-NMDA (though possibly of the Delta subfamily), and without any clear close homologs in metazoa or plants; glr-8 is expressed in the pharyngeal nervous system, the body wall mechanoreceptors ALM and PLM, and two other neurons (BDU and URB); glr-8 is expressed from embryogenesis to adulthood.
36	D1053.4	D1053.4	n/a	chrX 11,722,796	contains similarity to Naja kaouthia Cytotoxin 5 (Cytotoxin II).; SW:CX5_NAJKA
37	M01E5.2	M01E5.2	n/a	chrI 13,278,606	contains similarity to Pfam domains PF01018 (GTP1/OBG) , PF01926 (GTPase of unknown function) contains similarity to Interpro domains IPR014100 (GTP-binding protein Obg/CgtA), IPR005225 (Small GTP-binding protein), IPR006169 (GTP1/OBG subdomain), IPR002917 (GTP-binding protein, HSR1-related), IPR006073 (GTP1/OBG)
38	clec-121	Y25C1A.4	n/a	chrII 3,103,522	C. elegans CLEC-121 protein; contains similarity to Interpro domains IPR000104 (Antifreeze protein, type I), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
39	fbxa-95	F28F8.4	n/a	chrV 15,572,053	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
40	ggr-3	F09C12.1	n/a	chrII 5,131,702	ggr-3 encodes a predicted member of the GABA/ glycine receptor family of ligand-gated chloride channels; expressed in the AVA, AVB, SMDD, DVA, SIAD, and in some other neurons of the nerve ring.
41	secs-1	D1054.13	n/a	chrV 10,803,314	C. elegans SECS-1 protein; contains similarity to Pfam domain PF05889 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) contains similarity to Interpro domains IPR015424 (Pyridoxal phosphate-dependent transferase, major region), IPR008829 (Soluble liver antigen/liver pancreas antigen)
42	srv-17	C06E7.7	n/a	chrIV 5,868,915	C. elegans SRV-17 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
43	R09E12.6	R09E12.6	n/a	chrV 767,566	contains similarity to Pfam domain PF06869 Protein of unknown function (DUF1258) contains similarity to Interpro domain IPR009667 (Protein of unknown function DUF1258)
44	C41D11.4	C41D11.4	n/a	chrI 4,442,876
45	Y17G7B.3	Y17G7B.3	n/a	chrII 11,990,838	Y17G7B.3 is orthologous to the human gene HYDROXYACYLGLUTATHIONE HYDROLASE (HAGH; OMIM:138760), which when mutated leads to disease.
46	B0035.16	B0035.16	n/a	chrIV 11,295,988	contains similarity to Pfam domain PF03054 tRNA methyl transferase contains similarity to Interpro domains IPR014729 (Rossmann-like alpha/beta/alpha sandwich fold), IPR004506 (tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase)
47	C10A4.5	C10A4.5	n/a	chrX 7,394,900
48	srw-96	K04F1.2	n/a	chrV 1,674,580	C. elegans SRW-96 protein; contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR006069 (ATPase, P-type cation exchange, alpha subunit)
49	B0361.7	B0361.7	n/a	chrIII 7,284,829	contains similarity to Pfam domain PF00328 Histidine acid phosphatase contains similarity to Interpro domain IPR000560 (Histidine acid phosphatase)
50	nhr-51	K06B4.1	n/a	chrV 15,677,024	C. elegans NHR-51 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)