UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	K03B4.6	K03B4.6	0	chrV 4,673,573	contains similarity to Pfam domain PF03236 Domain of unknown function DUF263 contains similarity to Interpro domains IPR004920 (Protein of unknown function DUF263), IPR000366 (Fungal pheromone mating factor STE2 GPCR)
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	T02E9.3	T02E9.3	n/a	chrV 11,364,314	T02E9.3 encodes a homolog of human melatonin type 1b receptors, and more generally of mammalian dopamine and serotonin (5-HT) receptors; T02E9.3 is partly required for male tail curling, with T02E9.3(RNAi) animals showing reduced curling in exogenous 5-HT; T02E9.3 is required for full sensitivity to 5-HT, normal brood sizes, and pharyngeal pumping; T02E9.3 is expressed in head and tail neurons.
4	sru-27	C38C3.2	n/a	chrV 1,500,054	C. elegans SRU-27 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
5	R05A10.4	R05A10.4	n/a	chrIV 14,172,772	contains similarity to Pfam domain PF07403 Protein of unknown function (DUF1505) contains similarity to Interpro domain IPR009981 (Protein of unknown function DUF1505)
6	F15D3.4	F15D3.4	n/a	chrI 11,568,010	contains similarity to Interpro domain IPR000215 (Protease inhibitor I4, serpin)
7	C50C3.5	C50C3.5	n/a	chrIII 8,179,701	contains similarity to Pfam domain PF00036 EF hand contains similarity to Interpro domains IPR001125 (Recoverin), IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand), IPR003299 (Flagellar calcium-binding protein (calflagin)), IPR000261 (EPS15 homology (EH))
8	unc-38	F21F3.5	n/a	chrI 4,899,335	unc-38 encodes a nicotinic acetylcholine receptor (nAChR) alpha subunit; UNC-38 is required for normal locomotion and egg-laying, and functions as a subunit of a ligand-gated ion channel that likely mediates fast actions of acetylcholine at neuromuscular junctions and in the nervous system; when coexpressed with ACR-2, ACR-3, UNC-29, and LEV-1, non-alpha nAChR subunits, the resulting multimer can form levamisole-gated channels; UNC-38 is expressed postsynaptically in muscles and neurons where it colocalizes with TAX-6, and with ACR-8, ACR-12, and UNC-29, respectively.
9	F02D8.1	F02D8.1	n/a	chrV 14,975,819	contains similarity to Rattus norvegicus P27 KIP1.; TR:O08769
10	R04F11.1	R04F11.1	n/a	chrV 12,309,572	R04F11.1 encodes a claudin homolog that may be required for normal cohesion of apical junctions in epithelia; R04F11.1 is worm-specific, with obvious homologs only in C. elegans; R04F11.1 has no obvious function in mass RNAi assays; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water.
11	clec-256	Y17D7B.6	n/a	chrV 18,772,129	C. elegans CLEC-256 protein; contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domains IPR006583 (CW), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
12	C44F1.1	C44F1.1	n/a	chrIII 3,761,814	contains similarity to Interpro domain IPR008967 (p53-like transcription factor, DNA-binding)
13	F56C4.2	F56C4.2	n/a	chrIV 10,642,026	contains similarity to Oryza sativa DNA binding protein S1FA.; SW:S1FA_ORYSA
14	C45G9.8	C45G9.8	n/a	chrIII 5,052,953
15	str-3	M7.13	n/a	chrIV 11,099,437	str-3 encodes a seven transmembrane chemosensory receptor; STR-3 is expressed in the ASI chemosensory neurons; STR-3 expression in ASI is repressed in the presence of dauer pheromone at concentrations lower than that which induces dauer formation.
16	F12A10.5	F12A10.5	n/a	chrII 5,481,296	contains similarity to Pfam domain PF00036 EF hand contains similarity to Interpro domains IPR001125 (Recoverin), IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand), IPR008080 (Parvalbumin), IPR003299 (Flagellar calcium-binding protein (calflagin))
17	C30B5.5	C30B5.5	n/a	chrII 6,204,855	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR013806 (Kringle-like fold), IPR000276 (GPCR, rhodopsin-like)
18	fbxa-110	Y102A5C.8	n/a	chrV 16,937,848	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
19	T19D2.3	T19D2.3	n/a	chrX 3,939,726
20	sulp-4	K12G11.1	n/a	chrV 11,877,220	sulp-4 encodes one of eight C. elegans members of the sulfate permease family of anion transporters; by homology, SULP-4 is predicted to function as an anion transporter that regulates cellular pH and volume via transmembrane movement of electrolytes and fluids and when expressed in Xenopus oocytes, SULP-4 exhibits robust transport of sulfate and more modest transport of chloride ions and oxalate; a SULP-4::GFP fusion is expressed in the apical canaliculae of the excretory cell and also in some head neurons.
21	F18A11.5	F18A11.5	n/a	chrII 13,010,794	contains similarity to Pfam domains PF02214 (K+ channel tetramerisation domain) , PF03931 (Skp1 family, tetramerisation domain) contains similarity to Interpro domains IPR001232 (SKP1 component), IPR016072 (SKP1 component, dimerisation), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation), IPR016073 (SKP1 component, POZ)
22	C31H2.3	C31H2.3	n/a	chrX 5,152,942
23	fbxa-141	D1025.3	n/a	chrX 14,512,622	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
24	nhr-195	F59E11.10	n/a	chrV 8,971,529	C. elegans NHR-195 protein; contains similarity to Pfam domain PF00105 Zinc finger, C4 type (two domains) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
25	Y6B3B.3	Y6B3B.3	n/a	chrI 13,716,143	contains similarity to Interpro domain IPR010133 ()
26	C02H7.2	C02H7.2	n/a	chrX 734,085	contains similarity to Pfam domains PF00001 (7 transmembrane receptor (rhodopsin family)) , PF01748 (Caenorhabditis serpentine receptor-like protein) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32), IPR000276 (GPCR, rhodopsin-like)
27	glb-14	F21A3.6	n/a	chrV 15,543,990	glb-14 encodes a globin with no obvious function in mass RNAi assays; glb-14 expression is induced by anoxia in a HIF-1 dependent manner, although it is also paradoxically upregulated in a hif-1 mutant background; glb-14 is downregulated in a daf-2(e1370) mutant background under normoxic conditions.
28	clec-199	C30H6.1	n/a	chrIV 17,352,393	C. elegans CLEC-199 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
29	F47G6.2	F47G6.2	n/a	chrI 1,475,611	contains similarity to Pfam domain PF00501 AMP-binding enzyme contains similarity to Interpro domain IPR000873 (AMP-dependent synthetase and ligase)
30	T12B3.1	T12B3.1	n/a	chrIV 7,383,567	contains similarity to Pfam domains PF00782 (Dual specificity phosphatase, catalytic domain) , PF00102 (Protein-tyrosine phosphatase) contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase), IPR000340 (Protein-tyrosine phosphatase, dual specificity), IPR000923 (Blue (type 1) copper domain)
31	srbc-56	F54B8.12	n/a	chrV 15,831,110	C. elegans SRBC-56 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
32	fbxa-30	ZC47.4	n/a	chrIII 1,275,041	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
33	tag-194	W02D3.6	n/a	chrI 6,730,509	C. elegans TAG-194 protein; contains similarity to Pfam domain PF00153 Mitochondrial carrier protein contains similarity to Interpro domains IPR002067 (Mitochondrial carrier protein), IPR002030 (Mitochondrial brown fat uncoupling protein), IPR001993 (Mitochondrial substrate carrier), IPR002113 (Adenine nucleotide translocator 1)
34	nhr-194	F59E11.8	n/a	chrV 8,969,321	C. elegans NHR-194 protein; contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
35	F13H8.6	F13H8.6	n/a	chrII 6,285,852
36	R12H7.4	R12H7.4	n/a	chrX 13,217,956	contains similarity to Homo sapiens similar to zinc-finger helicase; ENSEMBL:ENSP00000304137
37	srh-192	ZC132.7	n/a	chrV 4,313,561	C. elegans SRH-192 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
38	C30F2.2	C30F2.2	n/a	chrX 16,080,929	contains similarity to Interpro domain IPR001841 (Zinc finger, RING-type)
39	W02D7.3	W02D7.3	n/a	chrV 8,294,341
40	psa-1	Y113G7B.23	n/a	chrV 20,239,752	psa-1 encodes an ortholog of SWI3, a component of the SWI/SNF complex that is conserved from yeast to mammals and that is involved in chromatin remodeling; psa-1 is probably required during mitosis of the T cells for asymmetric cell division, and in addition, is required for embryonic and larval development, as well as normal levels of fertility; psa-1 exhibits strong genetic interactions with lin-35/Rb, as psa-1 larval lethality and sterility at 20 degrees C are greatly enhanced in lin-35;psa-1 double mutants.
41	srd-71	C13B7.4	n/a	chrV 2,424,746	C. elegans SRD-71 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR001614 (Myelin proteolipid protein PLP), IPR003002 (7TM chemoreceptor, subfamily 1), IPR002016 (Haem peroxidase, plant/fungal/bacterial)
42	R13A1.5	R13A1.5	n/a	chrIV 7,191,489
43	Y43F8C.11	Y43F8C.11	n/a	chrV 19,670,774	contains similarity to Mus sp Interleukin-3 receptor beta subunit (Fragment).; TR:Q64130
44	clec-211	F19F10.6	n/a	chrV 7,560,915	C. elegans CLEC-211 protein; contains similarity to Interpro domain IPR016187 (C-type lectin fold)
45	M04D8.5	M04D8.5	n/a	chrIII 10,032,724	contains similarity to Periplaneta americana Large conductance calcium activated potassium channel pSlo spliceforms1-5A.; TR:Q8I9V1
46	K08C9.6	K08C9.6	n/a	chrI 11,499,274	contains similarity to Archaeoglobus fulgidus Hypothetical protein AF0327.; TR:O29920
47	F37C4.1	F37C4.1	n/a	chrIV 3,890,907	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
48	F01D4.8	F01D4.8	n/a	chrIV 10,451,925	contains similarity to Pfam domain PF00291 Pyridoxal-phosphate dependent enzyme contains similarity to Interpro domain IPR001926 (Pyridoxal phosphate-dependent enzyme, beta subunit)
49	ZK112.5	ZK112.5	n/a	chrIII 7,738,805
50	R02F2.8	R02F2.8	n/a	chrIII 5,494,067	contains similarity to Pfam domain PF01490 Transmembrane amino acid transporter protein contains similarity to Interpro domains IPR002091 (Aromatic amino acid permease), IPR013057 (Amino acid transporter, transmembrane)