UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	K03B4.4	K03B4.4	2e-37	chrV 4,684,430	contains similarity to Interpro domain IPR002411 (Cereal allergen/alpha-amylase inhibitor, rice-type)
2	srj-15	Y40B10B.2	n/a	chrV 1,963,860	C. elegans SRJ-15 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR002120 (Thyrotrophin-releasing hormone receptor)
3	fip-3	C06E1.5	n/a	chrIII 8,589,320	C. elegans FIP-3 protein ;
4	B0524.5	B0524.5	n/a	chrIII 1,892,549	contains similarity to Homo sapiens hypothetical protein; ENSEMBL:ENSP00000352916
5	W05E10.2	W05E10.2	n/a	chrV 11,688,773	contains similarity to Homo sapiens Hypothetical protein; ENSEMBL:ENSP00000288462
6	F15G9.2	F15G9.2	n/a	chrX 9,713,365	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8IAW6
7	K03A11.5	K03A11.5	n/a	chrX 13,066,078	contains similarity to Enterobacteria phage RB49 Hypothetical protein.; TR:Q7Y3J5
8	sue-1	F07A5.5	n/a	chrI 7,365,960	C. elegans SUE-1 protein; contains similarity to Pfam domain PF00008 EGF-like domain contains similarity to Interpro domains IPR000742 (EGF-like, type 3), IPR006209 (EGF-like), IPR006210 (EGF), IPR013032 (EGF-like region, conserved site)
9	lpr-2	T12A7.5	n/a	chrIV 11,783,102	C. elegans LPR-2 protein; contains similarity to Interpro domains IPR012674 (Calycin), IPR011038 (Calycin-like), IPR002345 (Lipocalin)
10	clec-211	F19F10.6	n/a	chrV 7,560,915	C. elegans CLEC-211 protein; contains similarity to Interpro domain IPR016187 (C-type lectin fold)
11	C49C3.15	C49C3.15	n/a	chrIV 17,334,573	contains similarity to Interpro domain IPR002101 (Myristoylated alanine-rich C-kinase substrate MARCKS)
12	clec-10	C03H5.1	n/a	chrII 403,400	C. elegans CLEC-10 protein; contains similarity to Pfam domains PF00431 (CUB domain) , PF00059 (Lectin C-type domain) (2)contains similarity to Interpro domains IPR002345 (Lipocalin), IPR000859 (CUB), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
13	grl-8	ZC487.5	n/a	chrV 6,732,495	grl-8 encodes a hedgehog-like protein, with an N-terminal signal sequence and a C-terminal Ground-like (Grl) domain; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
14	sre-54	C50E10.6	n/a	chrII 12,333,899	C. elegans SRE-54 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domains IPR004151 (C. elegans Sre G protein-coupled chemoreceptor), IPR000366 (Fungal pheromone mating factor STE2 GPCR)
15	F08F3.1	F08F3.1	n/a	chrV 5,447,387
16	acr-15	F25G6.4	n/a	chrV 8,554,009	A homolog of an alpha type nicotinic acetylcholine receptor subunit involved in the mediation of fast synaptic transmission at neuromuscular junctions.
17	Y47D3B.3	Y47D3B.3	n/a	chrIII 11,400,137	contains similarity to Homo sapiens Low-density lipoprotein receptor-related protein 2 precursor; ENSEMBL:ENSP00000263816
18	ZC15.1	ZC15.1	n/a	chrV 20,302,899	contains similarity to Interpro domains IPR001878 (Zn-finger, CCHC type), IPR000345 (Cytochrome c heme-binding site)
19	unc-46	C04F5.3	n/a	chrV 5,098,120	unc-46 encodes a novel protein with a single predicted transmembrane domain; UNC-46 and UNC-47, a novel transmembrane vesicular GABA transporter, are required in GABAergic neurons for all GABA neurotransmission, specifically for loading of GABA into synaptic vesicles, where UNC-46 is localized; UNC-46 localization requires UNC-47, which when overexpressed can rescue unc-46 mutant animals.
20	F40G9.8	F40G9.8	n/a	chrIII 164,235
21	str-47	F07C4.1	n/a	chrV 7,646,392	C. elegans STR-47 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
22	T10D4.3	T10D4.3	n/a	chrII 3,130,228	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)
23	aqp-6	C32C4.2	n/a	chrV 10,651,251	apq-6 encodes an aquaporin whose expression in Xenopus oocytes increases water permeability five- to seven-fold; aqp-6 has no function in mass RNAi assays, perhaps reflecting genetic redundancy with its paralogs AQP-4 and AQP-5; AQP-6 is expressed in the cilia and cell bodies of IL1 sensory neurons; AQP-6 is orthologous to human AQP8 (OMIM:603750).
24	F33D11.6	F33D11.6	n/a	chrI 5,845,654
25	C11E4.4	C11E4.4	n/a	chrX 9,594,806	contains similarity to Pfam domain PF00858 Amiloride-sensitive sodium channel contains similarity to Interpro domain IPR001873 (Na+ channel, amiloride-sensitive)
26	Y12A6A.2	Y12A6A.2	n/a	chrX 13,619,323	contains similarity to Phaseolus lunatus Double-headed bowman-birk inhibitor (Fragment).; TR:Q941H3
27	F02C12.2	F02C12.2	n/a	chrX 13,398,638	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR002424 (Insect alcohol dehydrogenase family), IPR003560 (2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding), IPR001100 (Pyridine nucleotide-disulphide oxidoreductase, class I)
28	npr-9	ZK455.3	n/a	chrX 11,330,259	C. elegans NPR-9 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002286 (P2 purinoceptor), IPR001556 (Bombesin receptor), IPR009144 (Thyrotropin-releasing hormone receptor), IPR000586 (Somatostatin receptor), IPR000405 (Galanin receptor), IPR000611 (Neuropeptide Y receptor), IPR000276 (GPCR, rhodopsin-like)
29	F21A10.4	F21A10.4	n/a	chrX 10,185,057	contains similarity to Mus musculus Tumor rejection antigen P815A.; SW:TUR8_MOUSE
30	C30B5.5	C30B5.5	n/a	chrII 6,204,855	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR013806 (Kringle-like fold), IPR000276 (GPCR, rhodopsin-like)
31	ubc-22	C06E2.7	n/a	chrX 8,868,414	ubc-22 encodes an E2 ubiquitin-conjugating enzyme orthologous to Saccharomyces cerevisiae UBC8 and human UBC1/HIP2 (Huntingtin interacting protein 2, OMIM:602846) which are involved in regulating fructose-1,6-bisphosphatase and huntingtin catabolism, respectively; by homology, UBC-22 is likely required for covalent attachment of ubiquitin to select target proteins to facilitate their degradation; however, as loss of UBC-22 activity via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of UBC-22 in C. elegans development and/or behavior is not yet known.
32	F35D2.4	F35D2.4	n/a	chrII 7,581,981	contains similarity to Interpro domain IPR009030 (Growth factor, receptor)
33	F49E12.7	F49E12.7	n/a	chrII 8,395,633	contains similarity to Mycobacterium tuberculosis Hypothetical protein (HoxN/HupN/NixA family nickel transporter).; TR:O05804
34	F11A5.13	F11A5.13	n/a	chrV 16,226,353	contains similarity to Clostridium acetobutylicum MDR-type permease.; TR:Q97D15
35	ZK896.1	ZK896.1	n/a	chrIV 12,874,056	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domain IPR003366 (CUB-like region)
36	clec-45	F07C4.2	n/a	chrV 7,638,344	C. elegans CLEC-45 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
37	T12B3.1	T12B3.1	n/a	chrIV 7,383,567	contains similarity to Pfam domains PF00782 (Dual specificity phosphatase, catalytic domain) , PF00102 (Protein-tyrosine phosphatase) contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase), IPR000340 (Protein-tyrosine phosphatase, dual specificity), IPR000923 (Blue (type 1) copper domain)
38	C24D10.8	C24D10.8	n/a	chrIV 5,165,608	n/a
39	F41E7.7	F41E7.7	n/a	chrX 10,311,728	contains similarity to Drosophila grimshawi Chorion protein S18.; SW:CH18_DROGR
40	ptr-19	Y39A1B.2	n/a	chrIII 10,786,410	ptr-19 encodes an ortholog of Drosophila and human PTCHD3, which defines one of seven paralogous families of sterol sensing domain (SSD) proteins; PTR-19 is required for normal development in mass RNAi assays; PTR-19 is expressed in pharynx, hypodermis, nervous system (including head neurons), and other cells.
41	T23F4.2	T23F4.2	n/a	chrII 1,164,528
42	F09C6.1	F09C6.1	n/a	chrV 16,887,916	contains similarity to Interpro domain IPR008999 (Actin-crosslinking proteins)
43	sro-1	D1022.6	n/a	chrII 7,461,799	C. elegans SRO-1 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
44	M05B5.6	M05B5.6	n/a	chrI 7,184,379	contains similarity to Homo sapiens Transient receptor potential cation channel subfamily A member 1; ENSEMBL:ENSP00000262209
45	str-87	F59E11.16	n/a	chrV 8,987,304	C. elegans STR-87 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
46	srab-12	C47A10.6	n/a	chrV 17,782,010	C. elegans SRAB-12 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
47	T14C1.1	T14C1.1	n/a	chrX 14,408,600	T14C1.1 encodes a homolog of the functionally active Fmrf Receptor (FR; CG2114) of D. melanogaster; it is thus possible that T14C1.1 is a receptor for one of the FMRF-like neurotransmitters in C. elegans (e.g., FLP-1 through FLP-12).
48	C38C3.6	C38C3.6	n/a	chrV 1,485,347	contains similarity to Interpro domain IPR000694 (Proline-rich region)
49	F54D12.8	F54D12.8	n/a	chrII 1,396,527	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domains IPR006583 (CW), IPR003609 (Apple-like)
50	acr-12	R01E6.4	n/a	chrX 13,534,608	acr-12 encodes a nicotinic acetylcholine receptor (nAChR) alpha subunit that is a member of the ACR-8-like group of C. elegans nAChR subunits; as an nAChR subunit, ACR-12 is predicted to mediate fast excitatory neurotransmission, however loss of acr-12 activity via mutation or RNAi results in no obvious defects; ACR-12 copurifies with UNC-29 and LEV-1, suggesting that ACR-12 can form receptors with these two non-alpha AChR subunits; an ACR-12::GFP fusion protein is expressed exclusively in ventral cord motor neurons, including the D neurons; in vivo, ACR-12 colocalizes with some, but not all, UNC-38-containing postsynaptic receptor clusters, suggesting that ACR-12 contributes to only a subset of these receptor clusters.