UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	cpx-2	K03A11.2	4e-44	chrX 13,067,761	C. elegans CPX-2 protein; contains similarity to Pfam domain PF05835 Synaphin protein contains similarity to Interpro domain IPR008849 (Synaphin)
2	T10C6.2	T10C6.2	n/a	chrV 16,013,354	contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
3	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
4	flp-6	F07D3.2	n/a	chrV 9,472,810	C. elegans FLP-6 protein; contains similarity to Pfam domain PF01581 FMRFamide related peptide family
5	F49C12.10	F49C12.10	n/a	chrIV 9,318,735	contains similarity to Pfam domain PF08241 Methyltransferase domain contains similarity to Interpro domain IPR013216 (Methyltransferase type 11)
6	C50F4.9	C50F4.9	n/a	chrV 9,523,727	contains similarity to Streptococcus agalactiae Hypothetical protein.; TR:Q8E2N5
7	ZC412.1	ZC412.1	n/a	chrV 14,855,683	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000611 (Neuropeptide Y receptor), IPR000276 (GPCR, rhodopsin-like)
8	fmo-2	K08C7.5	n/a	chrIV 10,683,426	fmo-2 encodes a flavin-containing monoxygenase homologous to human FMO1, FMO2, and FMO3 (OMIM:602079, mutated in trimethylaminuria).
9	F33D11.8	F33D11.8	n/a	chrI 5,854,677
10	F08H9.4	F08H9.4	n/a	chrV 14,463,959	F08H9.4 encodes a heat shock protein (HSP) of the HSP16 class; unlike most HSP16s in C. elegans, it is specifically expressed in a particular tissue (the excretory canal and ventral nerve-cord neurons), and its expression is only mildly induced by heat shock; however, F08H9.4 expression is increased by heat shock, is induced in a new tissue type (intestine) by heat shock, and probably aids heat shock resistance, since F08H9.4(RNAi) animals die as embryos in heat shock at a higher rate than normal; in general, HSP16 proteins are thought to act as passive ligands for unfolded proteins that keep them safe from aggregation until the proteins can be refolded by a large (ATP-consuming) HSP.
11	ZK816.1	ZK816.1	n/a	chrX 3,359,733
12	C13A10.2	C13A10.2	n/a	chrII 1,357,598
13	K04F1.12	K04F1.12	n/a	chrV 1,656,168	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
14	C55A1.6	C55A1.6	n/a	chrV 15,648,434	contains similarity to Lactococcus lactis Protein maturation protein.; TR:Q9CEV9
15	F25E5.9	F25E5.9	n/a	chrV 7,437,693
16	C08F11.2	C08F11.2	n/a	chrIV 13,622,516	contains similarity to Methanobacterium thermoautotrophicum Hypothetical protein MTH421.; SW:Y421_METTH
17	F35C5.11	F35C5.11	n/a	chrII 12,909,598	contains similarity to Mus musculus Lymphocyte antigen Ly-6D precursor (Thymocyte B cell antigen) (ThB).; SW:LY6D_MOUSE
18	T17A3.10	T17A3.10	n/a	chrIII 155,573	contains similarity to Interpro domain IPR007110 (Immunoglobulin-like)
19	ins-3	ZK75.3	n/a	chrII 5,990,388	ins-3 encodes one of several insulin-related peptides; INS-3 is classified as a Type-beta insulin based on the predicted arrangement of disulfide bonds; gfp gene fusions with the promoter and enhancer regions indicate that INS-3 is expressed in some amphid sensory neurons.
20	C30B5.7	C30B5.7	n/a	chrII 6,225,999	contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR003944 (Protease-activated receptor 4)
21	E02H4.4	E02H4.4	n/a	chrX 14,259,690	contains similarity to Arabidopsis thaliana Uncharacterized protein At1g15830.1.; TR:Q3EDB7
22	C50F2.7	C50F2.7	n/a	chrI 3,900,880
23	twk-7	F22B7.7	n/a	chrIII 8,638,816	C. elegans TWK-7 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR013099 (Ion transport 2), IPR003092 (Potassium channel, two pore-domain, TASK)
24	sri-13	M01G12.13	n/a	chrI 12,141,648	C. elegans SRI-13 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
25	C18A11.2	C18A11.2	n/a	chrX 8,067,797
26	C02B8.7	C02B8.7	n/a	chrX 8,137,743
27	W05B10.4	W05B10.4	n/a	chrV 12,668,893	contains similarity to Pfam domain PF00788 Ras association (RalGDS/AF-6) domain contains similarity to Interpro domain IPR000159 (Ras-association)
28	nlp-10	F37A8.4	n/a	chrIII 3,934,743	nlp-10 encodes four predicted neuropeptide-like proteins; nlp-10 is part of a GGxY neuropeptide family that has members in several other nematode species; nlp-10 is expressed in a variety of neurons, including ASK, ADL, CAN, two lateral neurons, two anterior pharyngeal neurons, one tail neuron, and one male tail neuron; as loss of nlp-10 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of nlp-10-encoded peptides in development and/or behavior is not yet known.
29	T05H10.8	T05H10.8	n/a	chrII 8,060,196	contains similarity to Streptococcus pneumoniae Cell division regulator, negative regulator of FtsZ ringsformation.; TR:Q8DQE5
30	srh-209	ZK262.11	n/a	chrV 18,404,256	C. elegans SRH-209 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
31	pqn-97	ZK488.10	n/a	chrV 609,465	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
32	F47F2.3	F47F2.3	n/a	chrX 3,894,817	contains similarity to Interpro domain IPR013032 (EGF-like region, conserved site)
33	M03E7.4	M03E7.4	n/a	chrV 5,611,266	M03E7.4 encodes a protein, predicted to be secreted, with one chitin-binding peritrophin-A and three low-density lipoprotein receptor domain class A domains; M03E7.4 has no obvious function in mass RNAi assays.
34	F54B8.4	F54B8.4	n/a	chrV 15,816,808	The F54B8.4 gene encodes a homolog of Death Associated Protein 1 (DAP-1) protein that may be involved in apoptosis.
35	gst-11	R11G1.3	n/a	chrX 3,633,139	C. elegans GST-11 protein; contains similarity to Pfam domains PF00043 (Glutathione S-transferase, C-terminal domain) , PF02798 (Glutathione S-transferase, N-terminal domain) contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR003080 (Glutathione S-transferase, alpha class), IPR012335 (Thioredoxin fold), IPR004046 (Glutathione S-transferase, C-terminal), IPR004045 (Glutathione S-transferase, N-terminal), IPR010987 (Glutathione S-transferase, C-terminal-like)
36	C13A2.7	C13A2.7	n/a	chrV 7,266,655
37	glc-3	ZC317.3	n/a	chrV 5,451,485	The glc-3 gene encodes a fipronil and BIDN-sensitive, but picrotoxinin-insensitive, L-glutamate-gated chloride channel subunit.
38	srh-39	C06A8.7	n/a	chrII 7,764,656	C. elegans SRH-39 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
39	sre-20	ZC455.7	n/a	chrV 12,783,819	C. elegans SRE-20 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domains IPR004151 (C. elegans Sre G protein-coupled chemoreceptor), IPR008075 (Lipocalin-1 receptor)
40	aqp-5	C35A5.1	n/a	chrV 10,492,631	aqp-5 encodes a putative aquaporin with no known substrate, since AQP-5 expressed in Xenopus oocytes has no effect on water, glycerol, or urea permeability; AQP-5 also has no function in mass RNAi assays, perhaps reflecting genetic redundancy with its paralogs AQP-4 and AQP-6; AQP-5 is expressed in I1 and I2 pharyngeal interneurons, and is orthologous to human AQP8 (OMIM:603750).
41	bbs-8	T25F10.5	n/a	chrV 6,763,757	bbs-8 encodes a tetratricopeptide repeat (TPR)-containing protein that is orthologous to the human Bardet-Biedl syndrome protein, BBS8; in C. elegans, bbs-8 activity is required for cilia biogenesis and function; accordingly, bbs-8 mutant animals display odorant chemotaxis defects and exhibit both aberrant motility and abnormal localization of at least two intraflagellar transport (IFT) protein markers; a BBS-8::GFP translational fusion is expressed exclusively in ciliated head and tail neurons, where it localizes predominantly to the base of cilia, known as the ciliary transition zone; BBS-8::GFP is also observed moving bidirectionally (anterograde and retrograde) along the ciliary axoneme; DNA sequences upstream of bbs-8 contain X box DNA binding sites, suggesting that bbs-8 expression may be regulated by the DAF-19 RFX-type transcription factor.
42	C39D10.5	C39D10.5	n/a	chrX 7,891,348
43	C44H9.8	C44H9.8	n/a	chrV 12,847,707	contains similarity to Bacillus anthracis Sensory box histidine kinase PhoR.; TR:Q81L02
44	srh-19	F19G12.5	n/a	chrX 1,414,840	C. elegans SRH-19 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
45	srbc-50	F54B8.8	n/a	chrV 15,824,406	C. elegans SRBC-50 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
46	gst-2	K08F4.6	n/a	chrIV 10,140,892	C. elegans GST-2 protein; contains similarity to Pfam domains PF00043 (Glutathione S-transferase, C-terminal domain) , PF02798 (Glutathione S-transferase, N-terminal domain) contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR004046 (Glutathione S-transferase, C-terminal), IPR004045 (Glutathione S-transferase, N-terminal), IPR010987 (Glutathione S-transferase, C-terminal-like)
47	ubc-1	C35B1.1	n/a	chrIV 4,104,634	ubc-1 encodes an E2 ubiquitin-conjugating enzyme that contains a novel 40 amino acid C-terminal tail, and is homologous to Saccharomyces cerevisiae RAD6/UBC2 which is involved in DNA repair; although loss of UBC-1 activity via RNA-mediated interference (RNAi) does not result in any abnormalities, UBC-1 is able to complement the DNA repair defects of a Saccharomyces cerevisiae rad6 null mutant, suggesting that UBC-1 can function in the DNA repair pathway; ubc-1 mRNA is detectable in embryos.
48	K02F6.8	K02F6.8	n/a	chrII 2,533,862	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
49	C06B3.1	C06B3.1	n/a	chrV 13,903,319	contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR008365 (Prostanoid receptor), IPR003002 (7TM chemoreceptor, subfamily 1)
50	nas-28	F42A10.8	n/a	chrIII 6,182,093	C. elegans NAS-28 protein; contains similarity to Pfam domain PF01400 Astacin (Peptidase family M12A) contains similarity to Interpro domains IPR017050 (Peptidase M12A, astacin, nematode), IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR001506 (Peptidase M12A, astacin), IPR006026 (Peptidase, metallopeptidases), IPR000859 (CUB), IPR013032 (EGF-like region, conserved site)