UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	K02E7.4	K02E7.4	7e-135	chrII 1,073,572	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domain IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
2	T08G5.7	T08G5.7	n/a	chrV 14,044,675	contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR003656 (Zinc finger, BED-type predicted), IPR007087 (Zinc finger, C2H2-type)
3	ZK1098.5	ZK1098.5	n/a	chrIII 9,526,211	ZK1098.5 encodes a unfamiliar protein that is individually dispensable for viability and gross morphology in RNAi assays, but is cotranscribed with ZK1098.1 and thus might act in concert with it.
4	lin-1	C37F5.1	n/a	chrIV 2,288,106	lin-1 encodes an Ets-domain-containing transcription factor that is a member of the ETS gene family that includes human ELK1, 3, and 4 (OMIM:600247); LIN-1 functions as a general effector of MAP kinase-mediated signaling; when MAP kinase is inactive, LIN-1 forms a complex with LIN-31/WH that inhibits vulval cell fate specification; upon MAP kinase activation (vulval induction), LIN-1 is phosphorylated, dissociates from LIN-31, and becomes inactive, thus allowing for vulval development.
5	R10D12.7	R10D12.7	n/a	chrV 13,950,209	contains similarity to Pfam domain PF01679 Uncharacterized protein family UPF0057 contains similarity to Interpro domain IPR000612 (Protein of unknown function UPF0057)
6	taf-11.3	F43D9.5	n/a	chrIII 10,504,535	The taf-11.3 gene encodes an ortholog of human TATA-binding protein associated factor TAF11 (TAFII28, OMIM:600772) that is a component of the TFIID general transcription factor that recognizes the transcription start site; TAF-11.3 is required for proper post-embryonic development.
7	E02H9.4	E02H9.4	n/a	chrIII 2,457,255	contains similarity to Pfam domain PF03312 Protein of unknown function, DUF272 contains similarity to Interpro domain IPR004987 (Protein of unknown function DUF272)
8	F44E5.3	F44E5.3	n/a	chrII 11,763,830	contains similarity to Homo sapiens Hypothetical protein; ENSEMBL:ENSP00000304160
9	rod-1	F55G1.4	n/a	chrIV 7,481,969	C. elegans ROD-1 protein ; contains similarity to Caenorhabditis remanei Putative RoughDeal (Fragment).; TR:Q4TTM7
10	athp-1	C44B9.4	n/a	chrIII 10,887,899	C. elegans ATHP-1 protein; contains similarity to Pfam domains PF02178 (AT hook motif) (2), PF00628 (PHD-finger) contains similarity to Interpro domains IPR008984 (SMAD/FHA domain), IPR001965 (Zinc finger, PHD-type), IPR000637 (HMG-I and HMG-Y, DNA-binding), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR000294 (Vitamin K-dependent carboxylation/gamma-carboxyglutamic region), IPR000253 (Forkhead-associated), IPR011011 (Zinc finger, FYVE/PHD-type)
11	F22F7.6	F22F7.6	n/a	chrV 2,116,951	contains similarity to Homo sapiens N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase; ENSEMBL:ENSP00000309096
12	T14G10.8	T14G10.8	n/a	chrIV 10,146,609	contains similarity to Homo sapiens Splice isoform 1 of P08235 Mineralocorticoid receptor; ENSEMBL:ENSP00000281330
13	brc-2	T07E3.5	n/a	chrIII 6,901,783	brc-2 encodes a BRC domain-containing protein that is homologous to human BRCA2 which when mutated leads to early-onset breast cancer 2 or hereditary male breast cancer (OMIM:600185); in C. elegans, BRC-2 activity is essential for RAD-51-mediated repair of meiotic and radiation-induced double-strand breaks (DSBs); BRC-2 physically interacts with RAD-51 and single-stranded DNA and is required for proper localization of RAD-51 to sites of DNA damage and stabilization of RAD-51-DNA filaments; BRC-2 can also promote RAD-51-independent DSB repair via single-strand annealing (SSA) when the homologous recombination (HR) and nonhomologous end joining pathways (NHEJ) are compromised; in nonirradiated animals, BRC-2 is seen at diffuse, low levels in germline nuclei, but upon radiation treatment BRC-2 localizes to discrete foci that coincide with presumptive sites of DNA damage.
14	srh-233	Y113G7A.1	n/a	chrV 20,046,361	C. elegans SRH-233 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
15	C10E2.4	C10E2.4	n/a	chrX 16,750,349
16	T02G5.11	T02G5.11	n/a	chrII 7,080,284	contains similarity to Pfam domain PF05741 Nanos RNA binding domain contains similarity to Interpro domain IPR008705 (Zinc finger, Nanos)
17	F11C3.1	F11C3.1	n/a	chrI 14,869,588	contains similarity to Xenopus laevis ATP-dependent DNA helicase PIF1 (EC 3.6.1.-).; SW:Q0R4F1
18	srbc-18	C45H4.6	n/a	chrV 2,169,987	C. elegans SRBC-18 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
19	F38A1.13	F38A1.13	n/a	chrIV 1,265,538
20	C02B8.6	C02B8.6	n/a	chrX 8,134,694	contains similarity to Pfam domains PF00097 (Zinc finger, C3HC4 type (RING finger)) , PF02825 (WWE domain) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR004170 (WWE), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
21	K02D7.2	K02D7.2	n/a	chrIV 312,624	K02D7.2 encodes an ortholog of human SNAI2/SLUG (OMIM:602150, mutated in Waardenburg syndrome type IID) and Drosophila ESCARGOT; based on its orthology to SNAI2, K02D7.2 is predicted to be a transcriptional inhibitor.
22	Y54E2A.6	Y54E2A.6	n/a	chrII 14,768,030	contains similarity to Pfam domains PF00270 (DEAD/DEAH box helicase) (2), PF00271 (Helicase conserved C-terminal domain) (2), PF02889 (Sec63 Brl domain) (2)contains similarity to Interpro domains IPR011545 (DNA/RNA helicase, DEAD/DEAH box type, N-terminal), IPR004179 (Sec63), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR003593 (AAA+ ATPase, core), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
23	C49H3.9	C49H3.9	n/a	chrIV 7,908,266	contains similarity to Pfam domain PF07967 C3HC zinc finger-like contains similarity to Interpro domain IPR012935 (Zinc finger, C3HC-like)
24	R08C7.11	R08C7.11	n/a	chrIV 4,454,848
25	R148.2	R148.2	n/a	chrIII 3,184,321
26	srd-3	K10B4.5	n/a	chrII 127,822	C. elegans SRD-3 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR003002 (7TM chemoreceptor, subfamily 1)
27	F58F6.3	F58F6.3	n/a	chrIV 1,375,965
28	srv-8	F53F1.7	n/a	chrV 13,419,959	C. elegans SRV-8 protein; contains similarity to Interpro domains IPR002456 (GPCR, family 3, gamma-aminobutyric acid receptor, type B1), IPR002455 (GPCR, family 3, gamma-aminobutyric acid receptor, type B)
29	K06A4.4	K06A4.4	n/a	chrV 9,502,894	contains similarity to Pfam domain PF03083 MtN3/saliva family contains similarity to Interpro domain IPR004316 (MtN3 and saliva related transmembrane protein)
30	F59B2.13	F59B2.13	n/a	chrIII 9,025,413	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
31	srj-40	F38H12.2	n/a	chrV 4,102,865	C. elegans SRJ-40 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
32	srx-13	C44B12.4	n/a	chrIV 1,116,817	C. elegans SRX-13 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32), IPR000276 (GPCR, rhodopsin-like)
33	sru-47	F36D1.3	n/a	chrI 11,290,448	C. elegans SRU-47 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domains IPR015964 (Cytochrome C oxidase subunit II-like, transmembrane region), IPR003839 (Protein of unknown function DUF215)
34	Y63D3A.8	Y63D3A.8	n/a	chrI 14,116,402	contains similarity to Interpro domains IPR002114 (Phosphotransferase system, HPr serine phosphorylation site), IPR006634 (TRAM, LAG1 and CLN8 homology)
35	F29A7.5	F29A7.5	n/a	chrII 2,747,560
36	H42K12.2	H42K12.2	n/a	chrX 1,319,512
37	sprr-2	F42D1.3	n/a	chrX 14,802,137	C. elegans SPRR-2 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
38	Y116A8C.25	Y116A8C.25	n/a	chrIV 17,076,616	contains similarity to Pfam domain PF03881 Fructosamine kinase contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR005581 (Fructosamine kinase)
39	srz-74	K03D3.1	n/a	chrIV 16,330,219	C. elegans SRZ-74 protein ;
40	str-1	C42D4.5	n/a	chrIV 7,174,381	C. elegans STR-1 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
41	B0250.2	B0250.2	n/a	chrV 20,473,310	contains similarity to Drosophila erecta Female-specific transformer protein.; SW:TRSF_DROER
42	W06G6.9	W06G6.9	n/a	chrV 16,646,169	contains similarity to Ralstonia solanacearum Hypothetical protein RSc2317.; TR:Q8XX01
43	W09C5.9	W09C5.9	n/a	chrI 13,661,170	contains similarity to Lactococcus lactis Aspartate carbamoyltransferase (EC 2.1.3.2) (Aspartatestranscarbamylase) (ATCase).; SW:PYRB_LACLA
44	F11A1.2	F11A1.2	n/a	chrX 10,658,016
45	F08C6.5	F08C6.5	n/a	chrX 7,560,915	contains similarity to Interpro domain IPR003016 (2-oxo acid dehydrogenase, lipoyl-binding site)
46	ubc-19	Y69H2.6	n/a	chrV 18,688,049	ubc-19 encodes a predicted conjgating enzyme (UBCs/E2s) of the ubiquitin-conjugation system with a potentially low effect on embryonic viability, based on RNAi analysis.
47	grl-18	T05C3.4	n/a	chrV 5,487,265	grl-18 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central proline-rich region, and a C-terminal Ground-like (Grl) domain; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
48	C53A5.11	C53A5.11	n/a	chrV 14,563,580	contains similarity to Pfam domains PF01344 (Kelch motif) (5), PF07646 (Kelch motif) (3)contains similarity to Interpro domains IPR011043 (Galactose oxidase/kelch, beta-propeller), IPR000209 (Peptidase S8 and S53, subtilisin, kexin, sedolisin), IPR006652 (Kelch repeat type 1), IPR011498 (Kelch repeat type 2), IPR015916 (Galactose oxidase, beta-propeller), IPR013089 (Kelch related), IPR006651 (Kelch), IPR015915 (Kelch-type beta propeller)
49	C44H4.6	C44H4.6	n/a	chrX 14,597,741	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
50	Y52B11A.9	Y52B11A.9	n/a	chrI 11,036,452	contains similarity to Interpro domains IPR003604 (Zinc finger, U1-type), IPR005824 (KOW), IPR002358 (Ribosomal protein L6, conserved site-1), IPR007087 (Zinc finger, C2H2-type)