UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	grd-11	K02E2.2	0	chrV 20,356,705	grd-11 encodes a hedgehog-like protein, with (from N- to C-terminus) a signal sequence, four Ground domains, an short region of low-complexity sequence, and a Hint/Hog domain; the Hint/Hog domain is predicted to cut GRD-2 into two halves and then covalently link cholesterol to the C-terminus of the Ground domain; the four N-terminal Ground domains are predicted to form one or more cysteine-crosslinked proteins involved in intercellular signalling; Ground domains have subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; grd-11 has no obvious function in RNAi assays.
2	F19D8.2	F19D8.2	n/a	chrX 13,835,397	contains similarity to Homo sapiens Splice isoform 1 of Q9UMN6 Myeloid/lymphoid or mixed-lineage leukemia protein 4; ENSEMBL:ENSP00000222270
3	trx-2	B0024.9	n/a	chrV 10,314,942	C. elegans TRX-2 protein; contains similarity to Pfam domain PF00085 Thioredoxin contains similarity to Interpro domains IPR012335 (Thioredoxin fold), IPR015467 (Thioredoxin family), IPR001200 (Phosducin), IPR013766 (Thioredoxin domain), IPR006662 (Thioredoxin-related), IPR012336 (Thioredoxin-like fold)
4	K02A6.1	K02A6.1	n/a	chrX 8,219,837
5	srx-133	F09F3.4	n/a	chrV 13,849,303	C. elegans SRX-133 protein ;
6	Y6E2A.1	Y6E2A.1	n/a	chrV 15,710,013	contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000832 (GPCR, family 2, secretin-like)
7	clec-247	Y51A2A.1	n/a	chrV 18,285,606	C. elegans CLEC-247 protein; contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domains IPR002656 (Acyltransferase 3), IPR006621 (Nose resistant to fluoxetine-4, N-terminal)
8	clec-245	C31G12.2	n/a	chrV 18,187,150	C. elegans CLEC-245 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
9	tag-294	C54H2.3	n/a	chrX 5,761,796	C. elegans TAG-294 protein; contains similarity to Pfam domain PF00641 Zn-finger in Ran binding protein and others contains similarity to Interpro domain IPR001876 (Zinc finger, RanBP2-type)
10	nhr-230	Y17D7A.1	n/a	chrV 18,849,704	C. elegans NHR-230 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
11	pop-1	W10C8.2	n/a	chrI 2,826,881	pop-1 encodes an HMG box-containing protein that is the sole C. elegans member of the TCF/LEF family of transcription factors; in C. elegans, POP-1 functions as a component of the canonical and noncanonical Wnt signaling pathways that are required for cell migrations and binary cell fate decisions associated with asymmetric cell division, respectively; in yeast two-hybrid assays, the POP-1 N-terminal beta-catenin binding domain interacts with BAR-1/beta-catenin as well as with the more divergent beta-catenin, SYS-1; when coexpressed with SYS-1, POP-1 is able to activate transcription from a promoter with TCF binding sites; during development, maternally provided POP-1 is first detected in the nuclei of maturing oocytes and then in nearly all cells of the early embryo; in sister blastomeres in the early embryo, POP-1 is detected at lower levels in posterior blastomeres, such as E and P3, than in corresponding anterior blastomeres, MS and C; in later developmental stages, POP-1 is detected in a subset of tissues including hypodermal seam cells, gonadal precursors, and the developing vulva; in the vulva, POP-1 also exhibits an asymmetric staining pattern, with sister cells showing high or low levels of POP-1 depending upon their orientation along the anterior/posterior axis of the vulva.
12	C29F9.2	C29F9.2	n/a	chrIII 131,349	contains similarity to Homo sapiens Isoform 3 of MAP7 domain-containing protein 1; ENSEMBL:ENSP00000362241
13	D1046.3	D1046.3	n/a	chrIV 8,931,564	contains similarity to Pfam domain PF00153 Mitochondrial carrier protein contains similarity to Interpro domains IPR002067 (Mitochondrial carrier protein), IPR001993 (Mitochondrial substrate carrier)
14	K09B11.4	K09B11.4	n/a	chrIV 13,429,722	contains similarity to Patella vulgata Twist protein (Fragment).; TR:Q8WQQ8
15	B0350.3	B0350.3	n/a	chrIV 5,965,745
16	srt-32	C53A5.10	n/a	chrV 14,560,430	C. elegans SRT-32 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
17	H12D21.9	H12D21.9	n/a	chrV 14,908,258	contains similarity to Oceanobacillus iheyensis Hypothetical UPF0090 protein OB1594.; SW:YF94_OCEIH
18	clec-246	F16H6.2	n/a	chrV 18,190,268	C. elegans CLEC-246 protein ;
19	K07D4.4	K07D4.4	n/a	chrII 4,032,008
20	D1007.9	D1007.9	n/a	chrI 4,591,009
21	Y45F3A.5	Y45F3A.5	n/a	chrIII 10,585,998	contains similarity to Saccharomyces cerevisiae Protein involved in pre-rRNA processing, 18S rRNA synthesis, and snoRNA synthesis; component of the small subunit processome complex, which is required for processing of pre-18S rRNA; SGD:YOR310C
22	fbxa-113	Y113G7B.6	n/a	chrV 20,199,350	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
23	smf-2	K11G12.3	n/a	chrX 6,717,366	C. elegans SMF-2 protein; contains similarity to Pfam domain PF01566 Natural resistance-associated macrophage protein contains similarity to Interpro domain IPR001046 (Natural resistance-associated macrophage protein)
24	F40E3.6	F40E3.6	n/a	chrI 2,651,225
25	glb-12	C52A11.2	n/a	chrII 10,730,655	glb-12 encodes a globin; glb-12 transcription is higher in L3 and dauers than in young adults; in mass RNAi assays, glb-12 is required for embryonic viability, larval growth, and normal body shape, locomotion, and egg laying.
26	C44C10.5	C44C10.5	n/a	chrX 11,691,705	contains similarity to Homo sapiens Structural maintenance of chromosomes protein 1A; ENSEMBL:ENSP00000323421
27	C33D3.4	C33D3.4	n/a	chrX 10,488,757	contains similarity to Buchnera aphidicola Exodeoxyribonuclease V beta chain (EC 3.1.11.5).; SW:EX5B_BUCAP
28	tsp-11	B0563.2	n/a	chrX 9,164,502	C. elegans TSP-11 protein; contains similarity to Pfam domain PF00335 Tetraspanin family contains similarity to Interpro domains IPR000301 (CD9/CD37/CD63 antigen), IPR008952 (Tetraspanin)
29	B0391.3	B0391.3	n/a	chrV 15,616,248	contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000802 (Arsenical pump membrane protein)
30	srh-270	F37B4.5	n/a	chrV 2,860,866	C. elegans SRH-270 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
31	F48C5.1	F48C5.1	n/a	chrX 11,445,448	contains similarity to Pfam domain PF00047 Immunoglobulin domain contains similarity to Interpro domains IPR003598 (Immunoglobulin subtype 2), IPR000742 (EGF-like, type 3), IPR007110 (Immunoglobulin-like), IPR013032 (EGF-like region, conserved site), IPR013151 (Immunoglobulin)
32	str-240	K02H11.2	n/a	chrV 1,521,205	C. elegans STR-240 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
33	W03H9.3	W03H9.3	n/a	chrII 14,143,131	contains similarity to Streptomyces avermitilis Putative oxidoreductase.; TR:Q82DU1
34	F41G4.1	F41G4.1	n/a	chrX 16,841,928	contains similarity to Strongylocentrotus purpuratus 33 kDa inner dynein arm light chain, axonemal (p33).; SW:Q26630
35	F55E10.5	F55E10.5	n/a	chrX 8,335,538
36	cnk-1	R01H10.8	n/a	chrIII 10,274,812	cnk-1 encodes a protein that contains a SAM domain, a PDZ domain, and a PH domain.
37	T10G3.4	T10G3.4	n/a	chrV 13,483,233	contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
38	tag-83	F46F11.3	n/a	chrI 5,602,718	C. elegans TAG-83 protein ; contains similarity to Homo sapiens TNS1 protein; ENSEMBL:ENSP00000308321
39	srh-136	F36D3.6	n/a	chrV 16,496,767	C. elegans SRH-136 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
40	B0280.7	B0280.7	n/a	chrIII 7,111,015
41	F46B6.2	F46B6.2	n/a	chrV 9,773,402	contains similarity to Trypanosoma brucei Hypothetical protein.; TR:Q7YVJ9
42	K10D2.4	K10D2.4	n/a	chrIII 5,173,569
43	C09G9.3	C09G9.3	n/a	chrIV 8,871,534	contains similarity to Pfam domain PF01681 C6 domain contains similarity to Interpro domain IPR002601 (Protein of unknown function C6)
44	srt-5	C50H11.14	n/a	chrV 3,080,169	C. elegans SRT-5 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
45	unc-39	F56A12.1	n/a	chrV 14,374,572	unc-39 encodes a homeodomain transcription factor that belongs to the Six4/5 family of homeodomain proteins that includes human Six5; UNC-39 is required for axonal pathfinding in anterior-derived neurons and for specification of most mesodermal cell types and may regulate a developmental decision between migration and differentiation; UNC-39 is expressed in the embryo in anterior neurons, posteriorly derived mesoderm (somatic gonad, M mesoblast, and possibly the coelomocytes and muIntR), the CAN neurons, and body wall muscle.
46	F45F2.7	F45F2.7	n/a	chrV 8,523,135	contains similarity to Pfam domain PF03189 Protein of unknown function, DUF270 contains similarity to Interpro domains IPR003945 (NADH-plastoquinone oxidoreductase, chain 5), IPR004878 (Protein of unknown function DUF270), IPR016196 (MFS general substrate transporter)
47	ndx-3	Y38A8.1	n/a	chrII 4,954,109	The ndx-3 gene encodes a homolog of peroxisomal CoA diphosphatases in both S. cerevisiae (PCD1) and C. elegans (NDX-8); more generally, NDX-3 protein belongs to the family of NUDIX hydrolases.
48	Y38H8A.5	Y38H8A.5	n/a	chrIV 13,467,731	The Y38H8A.5 gene encodes a homolog of the human gene ZNF195 (or p57KIP2), which when mutated leads to Beckwith-Wiedemann syndrome (OMIM:130650).
49	fbxa-112	Y102A5C.13	n/a	chrV 16,947,523	C. elegans FBXA-112 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
50	W10G11.4	W10G11.4	n/a	chrII 3,563,054	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR002542 (Protein of unknown function DUF19)