UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	K02E2.1	K02E2.1	0	chrV 20,348,590	contains similarity to Salmo salar NADH-ubiquinone oxidoreductase chain 2 (EC 1.6.5.3).; SW:NU2M_SALSA
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	R10D12.6	R10D12.6	n/a	chrV 13,949,458	contains similarity to Pfam domain PF01679 Uncharacterized protein family UPF0057 contains similarity to Interpro domain IPR000612 (Protein of unknown function UPF0057)
4	dod-20	B0554.6	n/a	chrV 423,333	C. elegans DOD-20 protein; contains similarity to Pfam domain PF03409 Protein of unknown function (DUF274) contains similarity to Interpro domain IPR005071 (Protein of unknown function DUF274)
5	him-14	ZK1127.11	n/a	chrII 7,067,448	him-14 encodes a germline-specific member of the MutS family of DNA mismatch repair (MMR) proteins that is orthologous to human MSH4 and Saccharomyces cerevisiae Msh4p; during the pachytene stage of meiosis, HIM-14 activity is required for promoting crossing over between homologous chromosomes and thus, for chiasmata formation and proper chromosome segregation; in contrast, HIM-14 activity does not appear to be required for mismatch repair, nor for chromosome pairing or synapsis; him-14 mRNA expression is detected exclusively in the germline.
6	D2089.3	D2089.3	n/a	chrII 10,663,519	contains similarity to Homo sapiens hypothetical protein LOC150383; ENSEMBL:ENSP00000325301
7	B0496.1	B0496.1	n/a	chrIV 7,446,888	contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ), IPR000210 (BTB/POZ-like)
8	F14F9.6	F14F9.6	n/a	chrV 5,148,306
9	math-50	ZK250.8	n/a	chrII 1,957,153	math-50 encodes a protein which has a meprin-associated Traf homology (MATH) domain and may be involved in apoptosis.
10	B0228.6	B0228.6	n/a	chrII 7,754,791
11	W03G1.8	W03G1.8	n/a	chrIV 527,981
12	T25F10.4	T25F10.4	n/a	chrV 6,761,420	contains similarity to Interpro domain IPR006202 (Neurotransmitter-gated ion-channel ligand-binding)
13	ZK1037.1	ZK1037.1	n/a	chrV 15,311,784	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
14	C08E3.13	C08E3.13	n/a	chrII 1,632,158	C08E3.13 encodes a novel protein; expression studies indicate that C08E3.13 expression is positively regulated by signaling through the DBL-1/TGF-beta signaling pathway; in situ hybridization experiments reveal that C08E3.13 transcripts are expressed in the intestine and the vulva.
15	srb-8	F37C12.15	n/a	chrIII 7,172,652	C. elegans SRB-8 protein; contains similarity to Pfam domains PF02117 (C.elegans Sra family integral membrane protein) , PF02175 (C.elegans integral membrane protein Srb) contains similarity to Interpro domains IPR002184 (Serpentine beta receptor), IPR000344 (Nematode chemoreceptor, Sra)
16	srbc-11	C18B10.1	n/a	chrV 7,494,565	C. elegans SRBC-11 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
17	C08G5.6	C08G5.6	n/a	chrII 771,341
18	Y1A5A.2	Y1A5A.2	n/a	chrIII 3,984,495	contains similarity to Corynebacterium efficiens Putative nitrate transport protein.; TR:Q8FPW8
19	grk-2	W02B3.2	n/a	chrIII 678,078	grk-2 encodes a serine/threonine protein kinase that is most closely related to G protein-coupled receptor (GPCR) kinases; in C. elegans, grk-2 activity is required in chemosensory neurons for normal calcium influx during chemosensation, but is not required for GPCR downregulation; in regulating chemosensation, GRK-2 likely acts upstream of the ODR-3/G alpha protein, as overexpression of ODR-3 can rescue abnormal avoidance behavior in grk-2 mutants; GRK-2 is broadly expressed in the adult nervous system, with expression beginning as early as the 20-30-cell stage of embryonic development and continuing into adulthood.
20	str-204	F10D2.1	n/a	chrV 7,160,334	C. elegans STR-204 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
21	T20D4.6	T20D4.6	n/a	chrV 3,411,676	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR014752 (Arrestin, C-terminal), IPR011021 (Arrestin-like, N-terminal)
22	C12D5.5	C12D5.5	n/a	chrV 7,668,594
23	str-207	F26G5.4	n/a	chrV 4,952,370	C. elegans STR-207 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
24	C47F8.6	C47F8.6	n/a	chrI 12,320,092	contains similarity to Pfam domain PF01762 Galactosyltransferase contains similarity to Interpro domain IPR002659 (Glycosyl transferase, family 31)
25	Y45G12C.11	Y45G12C.11	n/a	chrV 2,551,494	contains similarity to Pfam domain PF03385 Protein of unknown function, DUF288 contains similarity to Interpro domain IPR005049 (Protein of unknown function DUF288)
26	T25D1.2	T25D1.2	n/a	chrX 16,516,558	contains similarity to Pfam domain PF06869 Protein of unknown function (DUF1258) contains similarity to Interpro domains IPR009667 (Protein of unknown function DUF1258), IPR011332 (Ribosomal protein, zinc-binding)
27	str-12	B0391.4	n/a	chrV 15,611,921	C. elegans STR-12 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
28	W01C8.1	W01C8.1	n/a	chrX 5,693,921
29	H35N09.2	H35N09.2	n/a	chrX 8,604,813
30	ugt-6	ZC455.4	n/a	chrV 12,796,799	C. elegans UGT-6 protein; contains similarity to Pfam domains PF04101 (Glycosyltransferase family 28 C-terminal domain) , PF00201 (UDP-glucoronosyl and UDP-glucosyl transferase) contains similarity to Interpro domains IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase), IPR007235 (Glycosyl transferase, family 28, C-terminal)
31	Y116A8C.5	Y116A8C.5	n/a	chrIV 16,925,748	Y116A8C.5 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; Y116A8C.5 has no clear orthologs in other organisms.
32	T08D2.8	T08D2.8	n/a	chrX 196,174	contains similarity to Pfam domain PF02985 HEAT repeat contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR000357 (HEAT), IPR016024 (Armadillo-type fold)
33	xnp-1	B0041.7	n/a	chrI 4,668,742	xnp-1 encodes an ATP-dependent DNA helicase of the SNF2 family that is orthologous to human XNP/ATR-X, which is associated with a number of X-linked mental retardation syndromes; in C. elegans, xnp-1 activity is required at high temperatures for embryogenesis, somatic gonad development, fertility, and vulval morphogenesis; in addition, animals doubly mutant for xnp-1 and lin-35/Rb, hpl-2/HP1, or nucleosome remodelling and histone deacetylase (NuRD) complex members such as lin-53 and let-418, display larval arrest with growth cessation but continued cell proliferation; xnp-1 is also required, with lin-35/Rb and hpl-2/HP1, for proper regulation of transgene expression; xnp-1 mRNA, detectable in embryos and the germline by in situ hybridization, is expressed at highest levels in embryos with decreasing levels seen in successive larval stages; xnp-1 transcriptional reporter fusions exhibit strong expression beginning at mid-embryogenesis but fading by embryonic morphogenesis; at hatching, expression is observed in all dividing cells including the P lineage, and at later larval stages expression is observed in the vulval precursor cells.
34	scl-1	F49E11.9	n/a	chrIV 13,056,795	scl-1 encodes a predicted secretory protein that is a member of the cysteine-rich secretory protein (CRISP) family; scl-1 activity positively regulates longevity and stress resistance; in wild-type animals, scl-1 mRNA is detected solely in eggs, while in daf-2 mutants it is detected in eggs and late adult stages; scl-1 expression appears to be under the control of the DAF-2/insulin-like signaling pathway as, in mixed-stage cultures, scl-1 mRNA levels are increased in daf-2 and age-1 mutants and undetectable in daf-16 mutants; scl-1 contains a DAF-16 consensus binding element within its predicted regulatory regions.
35	Y57G11C.7	Y57G11C.7	n/a	chrIV 14,755,336	contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
36	F59D6.4	F59D6.4	n/a	chrV 3,030,897	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
37	srw-113	ZK1037.9	n/a	chrV 15,333,837	C. elegans SRW-113 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
38	F55A4.4	F55A4.4	n/a	chrX 1,025,409	contains similarity to Pfam domain PF00035 Double-stranded RNA binding motif contains similarity to Interpro domains IPR001159 (Double-stranded RNA binding), IPR014720 (Double-stranded RNA-binding-like)
39	C17H1.8	C17H1.8	n/a	chrI 13,129,308	contains similarity to Pyrococcus furiosus DNA double-strand break repair rad50 ATPase.; SW:P58301
40	F30F8.1	F30F8.1	n/a	chrI 7,834,052	contains similarity to Mus musculus Nuclear factor of activated T cells 5 (T cell transcription factorsNFAT5) (NF-AT5) (Rel domain-containing transcription factor NFAT5).; SW:NFT5_MOUSE
41	F26A1.6	F26A1.6	n/a	chrIII 4,816,522	contains similarity to Lumbricus rubellus Amine oxidase-like protein (Fragment).; TR:Q94610
42	F19B10.6	F19B10.6	n/a	chrII 3,663,696
43	F46B3.8	F46B3.8	n/a	chrV 20,618,293	contains similarity to Pfam domain PF03380 Caenorhabditis protein of unknown function, DUF282 contains similarity to Interpro domain IPR005044 (Protein of unknown function DUF282, Caenorhabditis species)
44	elks-1	F42A6.9	n/a	chrIV 3,346,268	elks-1 encodes the C. elegans homolog of the vertebrate ELKS (glutamine, leucine, lysine, and serine-rich) proteins; although loss of elks-1 activity results in no obvious developmental or behavioral abnormalities, the ELKS-1 C-terminus interacts with the PDZ domain of UNC-10/RIM in vitro, and in vivo each protein appears to play a nonessential role in localizing the other to the presynaptic active zone; in addition to the active zone, ELKS-1 also localizes to the pharyngeal basal lamina.
45	F35E12.2	F35E12.2	n/a	chrV 13,723,593	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domain IPR003366 (CUB-like region)
46	str-112	F10D2.4	n/a	chrV 7,137,353	C. elegans STR-112 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
47	srb-1	C27D6.10	n/a	chrII 5,170,361	C. elegans SRB-1 protein; contains similarity to Pfam domain PF02175 C.elegans integral membrane protein Srb contains similarity to Interpro domain IPR002184 (Serpentine beta receptor)
48	T10H4.4	T10H4.4	n/a	chrV 15,271,231	contains similarity to Interpro domain IPR008957 (Fibronectin, type III-like fold)
49	C40H1.3	C40H1.3	n/a	chrIII 9,328,239	contains similarity to Homo sapiens Protein; VG:OTTHUMP00000003630
50	str-89	F59A1.4	n/a	chrV 17,670,073	C. elegans STR-89 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)