UCSC C. elegans Gene Sorter

JavaScript is disabled in your web browser

You must have JavaScript enabled in your web browser to use the Genome Browser

UCSC C. elegans Gene Sorter

genome assembly search

sort by display output

#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	inx-7	K02B2.4	0	chrIV 5,945,314	C. elegans INX-7 protein; contains similarity to Pfam domain PF00876 Innexin contains similarity to Interpro domain IPR000990 (Innexin)
2	srxa-10	R10E11.7	n/a	chrIII 9,795,820	C. elegans SRXA-10 protein; contains similarity to Pfam domain PF03383 Caenorhabditis serpentine receptor-like protein, class xa contains similarity to Interpro domain IPR005047 (Protein of unknown function DUF286, G protein-coupled receptor-like putative Caenorhabditis species)
3	nhr-76	C05G6.1	n/a	chrIV 630,739	C. elegans NHR-76 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
4	K04B12.3	K04B12.3	n/a	chrII 14,444,229	contains similarity to Anopheles gambiae str PEST AGAP010179-PA (Fragment).; TR:Q7Q0T1
5	K10C2.6	K10C2.6	n/a	chrX 6,451,568
6	twk-4	ZK1067.5	n/a	chrII 9,192,128	C. elegans TWK-4 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR003938 (Potassium channel, voltage-dependent, EAG/ELK/ERG), IPR013099 (Ion transport 2), IPR003092 (Potassium channel, two pore-domain, TASK)
7	K08F4.5	K08F4.5	n/a	chrIV 10,135,380	contains similarity to Paramecium tetraurelia Chromosome undetermined scaffold_96, whole genome shotgun sequence.; TR:A0EH68
8	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
9	sri-63	F39E9.3	n/a	chrII 3,288,198	C. elegans SRI-63 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR003544 (Cytochrome c-type biogenesis protein CcmB)
10	srsx-37	M01B2.7	n/a	chrV 15,258,341	C. elegans SRSX-37 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
11	fbxb-118	W06A11.3	n/a	chrII 4,063,201	C. elegans FBXB-118 protein ;
12	T07D3.3	T07D3.3	n/a	chrII 895,627	contains similarity to Homo sapiens CGI16-iso; ENSEMBL:ENSP00000368599
13	nhr-214	T07C5.3	n/a	chrX 12,701,293	C. elegans NHR-214 protein; contains similarity to Pfam domain PF00104 Ligand-binding domain of nuclear hormone receptor contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
14	K06H6.5	K06H6.5	n/a	chrV 577,400	contains similarity to Pfam domain PF04590 Protein of unknown function, DUF595 contains similarity to Interpro domain IPR007669 (Protein of unknown function DUF595)
15	T07D1.5	T07D1.5	n/a	chrX 2,419,146
16	srt-1	C13B7.1	n/a	chrV 2,436,754	C. elegans SRT-1 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
17	C47F8.3	C47F8.3	n/a	chrI 12,315,930	contains similarity to Pfam domain PF01762 Galactosyltransferase contains similarity to Interpro domain IPR002659 (Glycosyl transferase, family 31)
18	tbx-32	ZK380.1	n/a	chrX 1,656,225	C. elegans TBX-32 protein; contains similarity to Pfam domain PF00907 T-box contains similarity to Interpro domains IPR008967 (p53-like transcription factor, DNA-binding), IPR001699 (Transcription factor, T-box)
19	grl-28	T24A6.15	n/a	chrV 3,551,603	grl-28 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central low-complexity region, and a C-terminal Ground-like (Grl) domain; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
20	F13A2.1	F13A2.1	n/a	chrV 4,381,556
21	T21H3.5	T21H3.5	n/a	chrV 1,159,760
22	R03A10.5	R03A10.5	n/a	chrX 15,448,432	contains similarity to Pfam domains PF01105 (emp24/gp25L/p24 family/GOLD) , PF00650 (CRAL/TRIO domain) contains similarity to Interpro domains IPR001251 (Cellular retinaldehyde-binding/triple function, C-terminal), IPR000348 (emp24/gp25L/p24)
23	ZK402.3	ZK402.3	n/a	chrX 1,402,534	contains similarity to Pfam domain PF04435 Domain of unknown function (DUF545) contains similarity to Interpro domain IPR006570 (SPK)
24	srj-32	F07G11.5	n/a	chrV 7,296,979	C. elegans SRJ-32 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
25	F42C5.6	F42C5.6	n/a	chrIV 7,308,755
26	C11E4.7	C11E4.7	n/a	chrX 9,617,962
27	C54H2.4	C54H2.4	n/a	chrX 5,768,086
28	irk-2	M02A10.2	n/a	chrX 706,700	irk-2 encodes an inwardly rectifying potassium channel based on sequence homology to the the human potassium channel genes KCNJ1/KCNJ2.
29	fbxa-203	W05F2.5	n/a	chrI 3,372,801	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
30	tsp-3	Y39E4B.4	n/a	chrIII 13,213,403	C. elegans TSP-3 protein; contains similarity to Pfam domain PF00335 Tetraspanin family contains similarity to Interpro domain IPR000301 (CD9/CD37/CD63 antigen)
31	W07E6.3	W07E6.3	n/a	chrII 496,617	contains similarity to Interpro domain IPR000326 (Phosphatidic acid phosphatase type 2/haloperoxidase)
32	M142.5	M142.5	n/a	chrIII 10,931,599	contains similarity to Homo sapiens Isoform 1 of Protein LSM12 homolog; ENSEMBL:ENSP00000293406
33	F58B3.6	F58B3.6	n/a	chrIV 11,637,391	contains similarity to Pfam domains PF04836 (Interferon-related protein conserved region) , PF05004 (Interferon-related developmental regulator (IFRD)) contains similarity to Interpro domains IPR007701 (Interferon-related developmental regulator), IPR006921 (Interferon-related protein conserved region), IPR016024 (Armadillo-type fold)
34	mes-2	R06A4.7	n/a	chrII 14,386,115	mes-2 encodes a SET domain-containing protein that is orthologous to the Drosophila Polycomb group protein Enhancer of zeste [E(Z)]; as a member of a Polycomb-like chromatin repressive complex with MES-3 and MES-6, MES-2 is required maternally for normal germline development and during larval development, for anteroposterior patterning; during germline development, the MES-2/MES-3/MES-6 complex is believed to be essential for maintaining repression of the X chromosome, and in transgenic animals, the complex is necessary for germline repression of repetitive transgenes; in axial patterning, the MES-2/MES-3/MES-6 complex is required in somatic tissues for maintaining homeotic gene repression, acting upstream of the Hox genes lin-39, mab-5, and egl-5, as well as the egl-5 target gene lin-32; in addition, MES-2 activity is required for normal levels and localization of MES-3 in >24-cell-stage embryos; MES-2 expression is detected in the primordial germ cells and germline nuclei throughout development, in all nuclei in early embryos, and in somatic nuclei, including those of the male tail, in L2 and L3 larvae; in the nucleus, MES-2 appears to localize to chromatin.
35	C06A5.1	C06A5.1	n/a	chrI 6,017,022	contains similarity to Drosophila melanogaster Flybase gene name is CG3173-PA;; FLYBASE:CG3173
36	srbc-67	T24A6.10	n/a	chrV 3,539,627	C. elegans SRBC-67 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
37	Y54E2A.6	Y54E2A.6	n/a	chrII 14,768,030	contains similarity to Pfam domains PF00270 (DEAD/DEAH box helicase) (2), PF00271 (Helicase conserved C-terminal domain) (2), PF02889 (Sec63 Brl domain) (2)contains similarity to Interpro domains IPR011545 (DNA/RNA helicase, DEAD/DEAH box type, N-terminal), IPR004179 (Sec63), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR003593 (AAA+ ATPase, core), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
38	bli-3	F56C11.1	n/a	chrI 150,659	bli-3 encodes a large homolog of dual oxidase ('Ce-Duox1'), with an N-terminal peroxidase domain, two central calmodulin-binding EF hands, and a C-terminal superoxide-generating NADPH-oxidase domain; BLI-3 is required for dityrosine cross-linking of collagen, and thus for cuticular integrity; BLI-3 is thought to use cytosolic NADPH to generate reactive oxygen, which then drives the peroxidase ectodomain to cross-link free tyrosine in collagen; BLI-3 is expressed exclusively in hypodermal cells at low levels, with peaks of expression corresponding to collagen/cuticle biosynthesis.
39	rbr-2	ZK593.4	n/a	chrIV 10,923,428	rbr-2 encodes a histone H3 lysine 4 (H3K4) demethylase that is required for normally short lifespan and reliable vulval development, that regulates genome-wide levels of H3K4 trimethylation, and that interacts genetically with CLK-2, GLP-1, LIN-15, and SEM-5; RBR-2 is orthologous to budding yeast Jhd2p, Drosophila LID, and human JARID1A (OMIM:180202), JARID1B (OMIM:605393), JARID1C (OMIM:314690, mutated in mental retardation), and JARID1D (OMIM:426000); rbr-2(tm1231) homozygotes display excess trimethylated H3K4 (H3K4me3) and erratic vulval development (either vulvaless or multivulva); rbr-2(RNAi) animals show extended lifespans, a strong synthetic multivulva and H3K4me3 phenotype in a lin-15(n765ts) mutant background at permissive temperature, and abnormally slow growth with clk-2(mn159), glp-1(or178), or sem-5(n2019) mutant backgrounds.
40	C23H5.1	C23H5.1	n/a	chrIV 2,132,010	contains similarity to Pfam domains PF08242 (Methyltransferase domain) , PF08241 (Methyltransferase domain) contains similarity to Interpro domains IPR013217 (Methyltransferase type 12), IPR013216 (Methyltransferase type 11)
41	D1037.1	D1037.1	n/a	chrI 3,687,476	contains similarity to Pfam domains PF00035 (Double-stranded RNA binding motif) , PF01585 (G-patch domain) contains similarity to Interpro domains IPR001159 (Double-stranded RNA binding), IPR000694 (Proline-rich region), IPR014720 (Double-stranded RNA-binding-like), IPR000467 (D111/G-patch)
42	srx-8	C14C6.9	n/a	chrV 555,265	C. elegans SRX-8 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32), IPR000276 (GPCR, rhodopsin-like)
43	srh-131	Y102A5C.31	n/a	chrV 17,006,090	C. elegans SRH-131 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
44	mys-1	VC5.4	n/a	chrV 7,083,085	mys-1 encodes a MYST family histone acetyltransferase orthologous to Drosophila EG0007.7, human TIP60, and S. cerevisiae Esa1p; during vulval development, mys-1 acts as Class C synMuv gene: mys-1 mutations enhance mutations in components of the C. elegans NuRD and Rb repressor complexes that negatively regulate expression of genes required for vulval induction; in addition, mys-1(RNAi) enhances mutations in pha-4, which encodes a FoxA transcription factor required for pharyngeal organogenesis; mys-1 mutations also cause a synthetic slow growth phenotype in combination with mutations in the MCD-1 zinc-finger protein; thus, mys-1 activity is essential for proper cell fate specification of different cell types at different times during C. elegans development.
45	fbxa-37	ZC47.14	n/a	chrIII 1,286,023	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
46	F31F7.3	F31F7.3	n/a	chrV 6,269,506
47	clec-190	M199.4	n/a	chrIV 15,125,488	C. elegans CLEC-190 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR001304 (C-type lectin)
48	F28H6.6	F28H6.6	n/a	chrX 14,121,403	contains similarity to Interpro domain IPR010993 (Sterile alpha motif homology)
49	F54E7.6	F54E7.6	n/a	chrIII 5,660,439
50	atf-6	F45E6.2	n/a	chrX 12,482,840	atf-6 is an ortholog of mammalian ATF6alpha, a proximal sensor required for the unfolded protein response (UPR) in the endoplasmic reticulum (ER); ATF6alpha is a transmembrane protein, with a bZIP transcription factor domain in its cytosolic amino terminus that is released and activated by proteolytic cleavage upon ER stress; either ire-1 or xbp-1 deletions are synthetically lethal with atf-6 or pek-1 deletions, producing arrest in L2 larvae; RNAi of Y56A3A.2 (a S2P protease homolog) is synthetically lethal with ire-1(RNAi), consistent with the hypothesis that Y56A3A.2 cleaves ATF-6; atf-6 regulates few genes that are transcriptionally induced by UPR, but regulates roughly one-quarter of genes that require UPR constitutively; pdr-1 transcripts are strongly upregulated in a atf-6(ok551) mutant background, but atf-6(ok551);pdr-1(lg103) double mutants have a grossly normal phenotype ; atf-6 is dispensable for proper localization of GLR-1 glutamate receptors.