UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	K01A2.4	K01A2.4	1.0000000000000001e-129	chrII 310,134	contains similarity to Interpro domain IPR000814 (TATA-box binding)
2	crn-5	C14A4.5	n/a	chrII 10,593,065	C. elegans CRN-5 protein; contains similarity to Pfam domain PF01138 3' exoribonuclease family, domain 1 contains similarity to Interpro domain IPR001247 (Exoribonuclease, phosphorolytic domain 1)
3	pro-1	R166.4	n/a	chrII 10,540,649	pro-1 encodes a WD-repeat-containing protein that is orthologous to Saccharomyces cerevisiae IPI3; pro-1 activity is required for ribosome biogenesis and specifically, for efficient processing of intervening sequence 2 (ITS2) from rRNA intermediates during 26S rRNA maturation; during development, pro-1 is essential for larval growth, fertility, and normal cell division patterns; in addition, pro-1 is required cell autonomously in the somatic gonad for proper spatial and temporal regulation of germline development and proliferation; a pro-1 promoter::gfp fusion construct reveals that pro-1 is widely expressed in the embryo as well as in every major post-embryonic lineage including the somatic gonad.
4	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
5	W03C9.6	W03C9.6	n/a	chrII 11,957,465	contains similarity to Interpro domains IPR006052 (Tumor Necrosis Factor), IPR016196 (MFS general substrate transporter)
6	fbxa-216	Y47H9C.10	n/a	chrI 11,902,379	C. elegans FBXA-216 protein; contains similarity to Pfam domains PF01827 (FTH domain) , PF00646 (F-box domain) contains similarity to Interpro domains IPR002900 (Protein of unknown function DUF38, Caenorhabditis species), IPR001810 (Cyclin-like F-box)
7	K01A2.3	K01A2.3	1e-43	chrII 315,416
8	ZC190.4	ZC190.4	n/a	chrV 8,668,842	contains similarity to Pfam domains PF07647 (SAM domain (Sterile alpha motif)) , PF00536 (SAM domain (Sterile alpha motif)) contains similarity to Interpro domains IPR010993 (Sterile alpha motif homology), IPR013761 (Sterile alpha motif-type), IPR001660 (Sterile alpha motif SAM), IPR011510 (Sterile alpha motif homology 2)
9	sra-25	T26E3.9	n/a	chrI 12,687,150	C. elegans SRA-25 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domains IPR003945 (NADH-plastoquinone oxidoreductase, chain 5), IPR000344 (Nematode chemoreceptor, Sra)
10	D1025.1	D1025.1	n/a	chrX 14,521,627	contains similarity to Homo sapiens Splice isoform 3 of Q9ULU4 Protein kinase C binding protein 1; ENSEMBL:ENSP00000262975
11	cdr-1	F35E8.11	n/a	chrV 15,922,065	cdr-1 encodes a member of the cadmium-inducible lysosomal family that affects susceptibility to cadmium toxicity; expressed in intestinal cells.
12	clec-170	F38A1.1	n/a	chrIV 1,270,618	C. elegans CLEC-170 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
13	cln-3.3	ZC190.1	n/a	chrV 8,684,539	cln-3.3 encodes a predicted transmembrane protein that comprises one of three C. elegans homologs of human CLN3, (OMIM:607042, mutations are associated with Batten disease (also known as juvenile neuronal ceroid lipofuscinosis), a recessively inherited childhood neurodegenerative lysosomal storage disease); as loss of cln-3.3 via large-scale RNAi screens results in no obvious abnormalities, the precise role of cln-3.3 in C. elegans development and/or behavior is not yet known.
14	F59D12.5	F59D12.5	n/a	chrX 15,646,886
15	tag-170	C05D11.3	n/a	chrIII 6,432,606	C05D11.3/tag-170 encodes a thioredoxin domain-containing protein orthologous to human TXNDC9 and ENSG00000145268; in one-cell embryos, C05D11.3/TAG-170 is required for normal nuclear-centrosome rotation, male pronuclear migration, cytokinesis, and mitotic spindles, and for normally long astral microtubules; in early embryos, C05D11.3/TAG-170 is also required for normally rapid microtubule elongation; C05D11.3/tag-170 is expressed in larval and adult neurons and pharynx, and in vulva, with its strongest transcription in adults; like its mammalian ortholog, C05D11.3/TAG-170 protein is both nuclear and cytoplasmic.
16	C34C12.8	C34C12.8	n/a	chrIII 3,460,983	contains similarity to Pfam domain PF01025 GrpE contains similarity to Interpro domains IPR009012 (GrpE nucleotide exchange factor, head), IPR013805 (GrpE nucleotide exchange factor, coiled-coil), IPR000740 (GrpE nucleotide exchange factor)
17	F46F5.12	F46F5.12	n/a	chrII 807,746	contains similarity to Pfam domain PF03269 Caenorhabditis protein of unknown function, DUF268 contains similarity to Interpro domain IPR004951 (Protein of unknown function DUF268, Caenorhabditis species)
18	F53H1.1	F53H1.1	n/a	chrIV 1,303,451	contains similarity to Pfam domains PF00270 (DEAD/DEAH box helicase) , PF00271 (Helicase conserved C-terminal domain) contains similarity to Interpro domains IPR011545 (DNA/RNA helicase, DEAD/DEAH box type, N-terminal), IPR000629 (RNA helicase, ATP-dependent, DEAD-box, conserved site), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR014014 (RNA helicase, DEAD-box type, Q motif), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
19	dnj-14	K02G10.8	n/a	chrX 4,710,717	This gene encodes a protein containing a DnaJ ('J') domain.
20	F09G8.3	F09G8.3	n/a	chrIII 8,266,869	contains similarity to Pfam domain PF00380 Ribosomal protein S9/S16 contains similarity to Interpro domains IPR000754 (Ribosomal protein S9), IPR014721 (Ribosomal protein S5 domain 2-type fold)
21	taf-2	Y37E11B.4	n/a	chrIV 3,588,951	taf-2 encodes a member of the peptidase M1 family, a predicted aminopeptidase with similarity to human TBP-associated factor 2.
22	iff-2	F54C9.1	n/a	chrII 8,560,312	C. elegans IFF-2 protein; contains similarity to Pfam domains PF01287 (Eukaryotic initiation factor 5A hypusine, DNA-binding OB fold) , PF00467 (KOW motif) contains similarity to Interpro domains IPR001884 (Eukaryotic initiation factor 5A hypusine (eIF-5A)), IPR008991 (Translation protein SH3-like), IPR005824 (KOW), IPR012340 (Nucleic acid-binding, OB-fold), IPR014722 (Translation protein SH3-like, subgroup)
23	F52C12.2	F52C12.2	n/a	chrIV 1,956,651	contains similarity to Pfam domains PF04068 (Possible metal-binding domain in RNase L inhibitor, RLI) , PF04034 (Domain of unknown function (DUF367)) contains similarity to Interpro domains IPR007209 (Possible metal-binding region in RNase L inhibitor, RLI), IPR007177 (Protein of unknown function DUF367)
24	Y39A1A.22	Y39A1A.22	n/a	chrIII 10,705,056	contains similarity to Pfam domains PF03124 (EXS family) , PF03105 (SPX domain) contains similarity to Interpro domains IPR004342 (EXS, C-terminal), IPR004331 (SPX, N-terminal)
25	K03B8.6	K03B8.6	n/a	chrV 11,408,332	contains similarity to Interpro domain IPR000585 (Hemopexin)
26	C52B9.4	C52B9.4	n/a	chrX 4,262,578	contains similarity to Pfam domain PF06814 Lung seven transmembrane receptor contains similarity to Interpro domains IPR009637 (Transmembrane receptor, eukaryota), IPR008983 (Tumour necrosis factor-like)
27	tag-131	H38K22.3	n/a	chrIII 4,318,987	C. elegans TAG-131 protein; contains similarity to Pfam domain PF00173 Cytochrome b5-like Heme/Steroid binding domain contains similarity to Interpro domain IPR001199 (Cytochrome b5)
28	E04D5.2	E04D5.2	n/a	chrII 10,420,700	contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
29	F54F2.7	F54F2.7	n/a	chrIII 8,806,716	contains similarity to Interpro domain IPR011053 (Single hybrid motif)
30	H43I07.2	H43I07.2	n/a	chrV 4,201,565	contains similarity to Pfam domains PF01000 (RNA polymerase Rpb3/RpoA insert domain) , PF01193 (RNA polymerase Rpb3/Rpb11 dimerisation domain) contains similarity to Interpro domains IPR011263 (DNA-directed RNA polymerase, RpoA/D/Rpb3-type), IPR011262 (DNA-directed RNA polymerase, insert), IPR011261 (DNA-directed RNA polymerase, dimerisation)
31	W04C9.4	W04C9.4	n/a	chrI 462,326
32	C14B4.2	C14B4.2	n/a	chrV 19,341,070	contains similarity to Saccharomyces cerevisiae may be involved in connecting nuclear microtubules to the spindle pole body; SGD:YDR356W
33	E02C12.6	E02C12.6	n/a	chrV 9,370,290	contains similarity to Pfam domains PF02958 (Domain of unknown function (DUF227)) , PF07914 (Protein of unknown function (DUF1679)) contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species), IPR004119 (Protein of unknown function DUF227), IPR015897 (CHK kinase-like)
34	F32B6.9	F32B6.9	n/a	chrIV 9,904,788	contains similarity to Pfam domain PF01062 Bestrophin contains similarity to Interpro domain IPR000615 (Bestrophin)
35	C41H7.1	C41H7.1	n/a	chrII 3,016,764
36	D2030.3	D2030.3	n/a	chrI 7,579,667	contains similarity to Interpro domain IPR016024 (Armadillo-type fold)
37	M04C9.3	M04C9.3	n/a	chrI 9,353,710	contains similarity to Pfam domain PF06162 Caenorhabditis elegans protein of unknown function (DUF976) contains similarity to Interpro domains IPR010381 (Protein of unknown function DUF976, Caenorhabditis species), IPR016125 (Peptidase C15, pyroglutamyl peptidase I-like), IPR000816 (Peptidase C15, pyroglutamyl peptidase I)
38	Y106G6H.14	Y106G6H.14	n/a	chrI 10,472,796	contains similarity to Pfam domains PF07653 (Variant SH3 domain) , PF00018 (SH3 domain) , PF00023 (Ankyrin repeat) (3)contains similarity to Interpro domains IPR001452 (Src homology-3), IPR000108 (Neutrophil cytosol factor 2), IPR002110 (Ankyrin), IPR013315 (Spectrin alpha chain), IPR011511 (Variant SH3)
39	F09E5.8	F09E5.8	n/a	chrII 5,351,303	contains similarity to Pfam domain PF01168 Alanine racemase, N-terminal domain contains similarity to Interpro domains IPR011078 (Predicted pyridoxal phosphate-dependent enzyme, YBL036C type), IPR001608 (Alanine racemase, N-terminal)
40	C29F7.1	C29F7.1	n/a	chrX 13,413,508	contains similarity to Pfam domains PF02958 (Domain of unknown function (DUF227)) , PF07914 (Protein of unknown function (DUF1679)) contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species), IPR004119 (Protein of unknown function DUF227), IPR015897 (CHK kinase-like)
41	T05G5.1	T05G5.1	n/a	chrIII 9,741,123	contains similarity to Pfam domain PF00008 EGF-like domain contains similarity to Interpro domains IPR000742 (EGF-like, type 3), IPR006209 (EGF-like)
42	C05G5.1	C05G5.1	n/a	chrX 14,737,200	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
43	F07E5.5	F07E5.5	n/a	chrII 2,056,499	contains similarity to Pfam domain PF00098 Zinc knuckle contains similarity to Interpro domains IPR013084 (Zinc finger, CCHC retroviral-type), IPR001878 (Zinc finger, CCHC-type)
44	F55A4.1	F55A4.1	n/a	chrX 1,036,270	contains similarity to Pfam domain PF00957 Synaptobrevin contains similarity to Interpro domains IPR010908 (Longin), IPR011012 (Longin-like), IPR001388 (Synaptobrevin)
45	F23F1.4	F23F1.4	n/a	chrII 26,912
46	W02D3.2	W02D3.2	n/a	chrI 6,738,931	contains similarity to Pfam domain PF01180 Dihydroorotate dehydrogenase contains similarity to Interpro domains IPR001295 (Dihydroorotate dehydrogenase, core), IPR013785 (Aldolase-type TIM barrel), IPR005719 (Dihydroorotate dehydrogenase, class 2), IPR012135 (Dihydroorotate dehydrogenase, classes 1 and 2)
47	tag-289	F14F3.3	n/a	chrX 10,523,120	C. elegans TAG-289 protein; contains similarity to Pfam domain PF03062 MBOAT family contains similarity to Interpro domain IPR004299 (Membrane bound O-acyl transferase, MBOAT)
48	F58G6.3	F58G6.3	n/a	chrIV 9,653,835	contains similarity to Pfam domain PF04145 Ctr copper transporter family contains similarity to Interpro domains IPR007274 (Ctr copper transporter), IPR001463 (Sodium:alanine symporter)
49	F13A2.6	F13A2.6	n/a	chrV 4,403,625	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domain IPR006583 (CW)
50	E02H1.6	E02H1.6	n/a	chrII 9,597,035	E02H1.6 encodes an ortholog of human TAF9 (OMIM:600822; also known as AK6, adrenal gland protein AD-004 like protein, ADLP) and of S. cerevisiae Fap7p; like its human ortholog, E02H1.6 is nuclear, and is predicted to likewise be a TATA box binding protein (TBP)-associated factor mediating activation of RNA polymerase II; E02H1.6 prefers ATP and dATP as phosphate donors; E02H1.6's biochemical activity is unusual, since it also prefers AMP and dAMP as substrates, and tolerates CMP, TMP and shikimate acid as substrates as well; since yeast Fap7p promotes pre-rRNA cleavage, E02H1.6 may be multifunctional; in RNAi assays, E02H1.6 is required for normally fast growth; E02H1.6 is coexpressed with pme-2 in an operon, and thus, like PME-2, may function in DNA repair.