UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	H40L08.3	H40L08.3	0	chrX 15,073,031	contains similarity to Trichomonas vaginalis G3 Viral A-type inclusion protein, putative.; TR:A2EJ43
2	col-132	C39E9.9	n/a	chrIV 13,090,324	C. elegans COL-132 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (2)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat)
3	W04G5.3	W04G5.3	n/a	chrI 11,629,776	contains similarity to Arabidopsis thaliana Probable WRKY transcription factor 19 (WRKY DNA-binding protein 19).; SW:WR19_ARATH
4	srb-19	C54F6.11	n/a	chrV 7,518,912	C. elegans SRB-19 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
5	K03A11.4	K03A11.4	n/a	chrX 13,080,030	contains similarity to Pfam domain PF02995 Protein of unknown function (DUF229) contains similarity to Interpro domains IPR004245 (Protein of unknown function DUF229), IPR017850 (Alkaline-phosphatase-like, core domain)
6	btb-1	F40G9.4	n/a	chrIII 186,286	C. elegans BTB-1 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
7	nhr-171	C54F6.8	n/a	chrV 7,512,900	C. elegans NHR-171 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
8	acr-21	F27B3.2	n/a	chrIII 6,584,504	acr-21 encodes an alpha subunit of nicotinic acetylcholine receptor (nAChR); ACR-21 is a highly divergent member of the 'ACR-16' class of nAChR subunits, which includes ACR-7, ACR-9, ACR-10, ACR-11, ACR-14, ACR-15, ACR-16, and ACR-19, and is most closely related to the alpha-7 subunits of vertebrate nAChRs.
9	F40G12.2	F40G12.2	n/a	chrV 14,260,215	contains similarity to Interpro domain IPR003006 (Immunoglobulin/major histocompatibility complex, conserved site)
10	srd-8	B0547.4	n/a	chrIV 5,644,418	C. elegans SRD-8 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
11	srt-25	C16D9.7	n/a	chrV 8,257,371	C. elegans SRT-25 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
12	stdh-1	C06B3.4	n/a	chrV 13,907,215	stdh-1 encodes a putative steroid dehydrogenase required for normally short lifespan; STDH-1 is orthologous to human HSD17B3 (OMIM:605573, mutated in pseudohermaphroditism), HSD17B12 (OMIM:609574), and HSDL1, and paralogous to LET-767 and STDH-2/-4; STDH-1 is expressed in larval intestine, and in both larval and adult body wall muscle and neurons.
13	ceh-12	F33D11.4	n/a	chrI 5,841,090	ceh-12 encodes a homeobox protein orthologous to human HLXB9 (OMIM:142994, mutated in Currarino syndrome) that is required for normal synaptic inputs to motor neurons VA2-VA10 (sisters to VB3-VB11); ceh-12 is expressed in VB motor neurons, but repressed in their VA siblings by UNC-4 and UNC-37; unc-4 or unc-37 mutants show ectopic CEH-12 expression in VA neurons, which is both necessary and sufficient to induce VA neurons to form gap junctions with normally VB-specific interneurons; ceh-12 mutations have no grossly obvious phenotype, and have no effect on del-1 or acr-5 repression in VB neurons, but do suppress the backward movement defect of unc-4 mutants, and do derepress vab-7 (normally restricted to DB and VC motor neurons); CEH-12, like other HLXB9 orthologs, has an N-terminal eh1 domain that may interact with UNC-37/Groucho, and that may indicate CEH-12 to be a transcriptional repressor.
14	amt-2	F49E11.3	n/a	chrIV 13,044,619	amt-2 encodes a transmembrane protein that is one of four C. elegans members of the ammonium transporter AMT/Rh family of proteins predicted to function in transport of ammonium ions across the plasma membrane.
15	F31B9.2	F31B9.2	n/a	chrX 15,919,200	contains similarity to Mus musculus Radixin (ESP10).; SW:RADI_MOUSE
16	F16F9.1	F16F9.1	n/a	chrX 8,448,780	contains similarity to Interpro domain IPR006629 (LPS-induced tumor necrosis factor alpha factor)
17	E02C12.12	E02C12.12	n/a	chrV 9,380,457	contains similarity to Pfam domain PF07914 Protein of unknown function (DUF1679) contains similarity to Interpro domain IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species)
18	F16C3.2	F16C3.2	n/a	chrI 10,152,680	contains similarity to Clostridium acetobutylicum DNA repair protein recN, ATPase.; TR:Q97HD9
19	M163.7	M163.7	n/a	chrX 14,466,135	contains similarity to Reclinomonas americana Ribosomal protein L31.; TR:O21296
20	hlh-4	T05G5.2	n/a	chrIII 9,738,064	C. elegans HLH-4 protein; contains similarity to Pfam domain PF00010 Helix-loop-helix DNA-binding domain contains similarity to Interpro domains IPR015660 (Achaete-scute transcription factor related), IPR001092 (Basic helix-loop-helix dimerisation region bHLH), IPR000694 (Proline-rich region), IPR011598 (Helix-loop-helix DNA-binding)
21	T24C12.1	T24C12.1	n/a	chrX 2,200,143	contains similarity to Interpro domain IPR008952 (Tetraspanin)
22	clec-156	F26A1.11	n/a	chrIII 4,842,010	C. elegans CLEC-156 protein; contains similarity to Interpro domains IPR006077 (Vinculin/alpha-catenin), IPR000694 (Proline-rich region), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
23	F10D7.4	F10D7.4	n/a	chrX 17,380,140
24	srw-66	Y57G7A.4	n/a	chrII 1,270,733	C. elegans SRW-66 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
25	srg-13	T23F11.5	n/a	chrIII 4,673,171	C. elegans SRG-13 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domains IPR001411 (Tetracycline resistance protein, TetB), IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
26	del-1	E02H4.1	n/a	chrX 14,274,420	del-1 encodes an ion channel protein of the DEG/ENaC (degenerin/epithelial Na+ channel) family; like other members of the degenerin family, DEL-1 is predicted to function as a sensory mechanotransduction channel, however detailed analysis of the DEL-1 mutant phenotype has not yet been reported; DEL-1 is expressed postembryonically in the VA and VB motor neurons and in the FLP sensory neurons; the DEL-1 expression pattern overlaps that of UNC-8, an additional C. elegans degenerin involved in movement control, with which DEL-1 may coassemble to form mechanically activated cation channels.
27	F02E11.3	F02E11.3	n/a	chrII 3,273,416	contains similarity to Interpro domain IPR010993 (Sterile alpha motif homology)
28	K02D10.3	K02D10.3	n/a	chrIII 8,771,549
29	nhr-169	C54C8.1	n/a	chrI 12,443,002	C. elegans NHR-169 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
30	F15D3.8	F15D3.8	n/a	chrI 11,580,950	contains similarity to Methanocaldococcus jannaschii Chromosome partition protein smc homolog.; SW:Q59037
31	F16G10.11	F16G10.11	n/a	chrII 2,392,784	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
32	tbx-41	T26C11.1	n/a	chrX 1,865,937	C. elegans TBX-41 protein; contains similarity to Pfam domain PF00907 T-box contains similarity to Interpro domains IPR008967 (p53-like transcription factor, DNA-binding), IPR001699 (Transcription factor, T-box)
33	F07G6.5	F07G6.5	n/a	chrX 1,706,500
34	F37C4.1	F37C4.1	n/a	chrIV 3,890,907	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
35	F58G1.8	F58G1.8	n/a	chrII 12,925,362	contains similarity to Interpro domain IPR009022 (Elongation factor G, III and V)
36	F10G8.2	F10G8.2	n/a	chrI 10,022,221	contains similarity to Interpro domain IPR011009 (Protein kinase-like)
37	srd-49	R04B5.8	n/a	chrV 10,095,486	C. elegans SRD-49 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR003002 (7TM chemoreceptor, subfamily 1)
38	srbc-56	F54B8.12	n/a	chrV 15,831,110	C. elegans SRBC-56 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
39	F17C8.6	F17C8.6	n/a	chrIII 4,745,411	F17C8.6 encodes an alpha1 Ca2+ channel subunit; large-scale RNAi experiments indicate that during development F17C8.6, along with nca-2, may play a role in regulating egg size and shape.
40	T03G11.5	T03G11.5	n/a	chrX 5,168,923
41	T05E11.2	T05E11.2	n/a	chrIV 11,115,881	T05E11.2 encodes a claudin homolog that may be required for normal cohesion of apical junctions in epithelia; T05E11.2 is worm-specific, with a with highly divergent sequence lacking obvious homologs; T05E11.2 has no obvious function in mass RNAi assays; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water.
42	F49B2.6	F49B2.6	n/a	chrI 14,335,445	contains similarity to Pfam domain PF01433 Peptidase family M1 contains similarity to Interpro domains IPR014782 (Peptidase M1, membrane alanine aminopeptidase, N-terminal), IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR001930 (Peptidase M1, membrane alanine aminopeptidase)
43	C49A1.1	C49A1.1	n/a	chrI 14,214,978	contains similarity to Homo sapiens Plasminogen-related protein B precursor; ENSEMBL:ENSP00000245705
44	Y113G7A.12	Y113G7A.12	n/a	chrV 20,140,914
45	sru-35	C33D9.4	n/a	chrIV 8,789,328	C. elegans SRU-35 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
46	ZC404.7	ZC404.7	n/a	chrV 6,779,108
47	F46F5.10	F46F5.10	n/a	chrII 824,543	contains similarity to Pfam domain PF07801 Protein of unknown function (DUF1647) contains similarity to Interpro domain IPR012444 (Protein of unknown function DUF1647)
48	B0041.1	B0041.1	n/a	chrI 4,665,314
49	grd-8	C37C3.4	n/a	chrV 7,843,402	grd-8 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central low-complexity proline-rich domain, and a C-terminal Ground domain; GRD-8 is expressed in larval intestine and neurons; the grd-8 gene is directly bound by DAF-12 and requires DAF-12 for full transcription; GRD-8's Ground domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; GRD-8 is weakly required for normal molting; GRD-8 is also required for normal adult alae formation, growth to full size, locomotion, and male tail development; all of these requirements may reflect common defects in cholesterol-dependent hedgehog-like signalling or in vesicle trafficking.
50	str-217	Y102A5C.28	n/a	chrV 16,999,587	C. elegans STR-217 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)