UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	H35B03.1	H35B03.1	0	chrIV 5,727,641
2	wht-6	T26A5.1	n/a	chrIII 6,473,428	C. elegans WHT-6 protein; contains similarity to Pfam domains PF01061 (ABC-2 type transporter) , PF00005 (ABC transporter) contains similarity to Interpro domains IPR003439 (ABC transporter-like), IPR003593 (AAA+ ATPase, core), IPR013525 (ABC-2 type transporter)
3	gcy-18	ZK896.8	n/a	chrIV 12,863,005	gcy-18 encodes a receptor-type guanylyl cyclase that, along with gcy-8 and gcy-23, constitutes a subfamily of guanylyl cyclase genes in C. elegans; gcy-18 functions redundantly with gcy-8 and gcy-23, and upstream of tax-4, to regulate thermotaxis via the AFD thermosensory neurons, although of the three guanylyl cyclases required, genetic analyses suggest that GCY-18 is the primary guanylyl cyclase required; in addition, microarray experiments indicate that gcy-18 expression is induced in daf-16(RNAi); daf-2(RNAi) double mutants and repressed in daf-2(RNAi) mutants, suggesting that GCY-18 activity may contribute to a shortened lifespan; consistent with this, loss of gcy-18 activity via RNAi does result in lifespan extension; GCY-18 is expressed exclusively in the AFD thermosensory neurons, where it localizes to sensory endings.
4	C56E6.6	C56E6.6	n/a	chrII 6,542,233	contains similarity to Pfam domain PF00560 Leucine Rich Repeat contains similarity to Interpro domains IPR000483 (Cysteine-rich flanking region, C-terminal), IPR001611 (Leucine-rich repeat), IPR003591 (Leucine-rich repeat, typical subtype)
5	K11H12.4	K11H12.4	n/a	chrIV 674,988	contains similarity to Pfam domain PF03409 Protein of unknown function (DUF274) contains similarity to Interpro domain IPR005071 (Protein of unknown function DUF274)
6	C56A3.3	C56A3.3	n/a	chrV 13,533,300	C56A3.3 encodes a homolog of the functionally active Fmrf Receptor (FR; CG2114) of D. melanogaster; it is thus possible that C56A3.3 is a receptor for one of the FMRF-like neurotransmitters in C. elegans (e.g., FLP-1 through FLP-12).
7	F54C4.4	F54C4.4	n/a	chrIII 87,055
8	F29A7.3	F29A7.3	n/a	chrII 2,753,579	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domain IPR006583 (CW)
9	ins-24	ZC334.3	n/a	chrI 14,031,394	ins-24 encodes an insulin-like peptide of the insulin superfamily of proteins (OMIM:176730, 147440); INS-24 is one of 38 insulin-like peptides in C. elegans, but as loss of INS-24 function via RNA-mediated interference does not result in any abnormalities, the precise role of INS-24 in C. elegans development is not yet clear.
10	gnrr-5	H22D07.1	n/a	chrV 4,452,877	C. elegans GNRR-5 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
11	C32H11.4	C32H11.4	n/a	chrIV 12,922,267	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domain IPR003366 (CUB-like region)
12	srz-70	C09G12.6	n/a	chrIV 3,478,198	C. elegans SRZ-70 protein ;
13	F57C12.2	F57C12.2	n/a	chrX 548,426	contains similarity to Pfam domain PF04670 Gtr1/RagA G protein conserved region contains similarity to Interpro domains IPR009053 (Prefoldin), IPR006762 (Gtr1/RagA G protein)
14	str-4	C50B6.10	n/a	chrV 13,338,836	C. elegans STR-4 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
15	Y81G3A.4	Y81G3A.4	n/a	chrII 13,092,774	contains similarity to Guillardia theta 60S acidic ribosomal protein P0.; TR:Q98S65
16	pqn-84	Y41C4A.5	n/a	chrIII 11,701,451	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
17	Y53C10A.5	Y53C10A.5	n/a	chrI 12,000,702	contains similarity to Interpro domain IPR000608 (Ubiquitin-conjugating enzyme, E2)
18	btb-15	C08E3.2	n/a	chrII 1,611,924	C. elegans BTB-15 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
19	W02B8.3	W02B8.3	n/a	chrII 13,917,920	contains similarity to Pfam domain PF04870 Protein of unknown function, DUF644 contains similarity to Interpro domain IPR006954 (Protein of unknown function DUF644)
20	str-264	C06B8.4	n/a	chrV 15,491,810	C. elegans STR-264 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
21	srab-9	C36C5.6	n/a	chrV 3,140,609	C. elegans SRAB-9 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
22	srd-70	F48F5.4	n/a	chrV 20,450,660	C. elegans SRD-70 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
23	C04E7.1	C04E7.1	n/a	chrX 359,435
24	F02E11.2	F02E11.2	n/a	chrII 3,267,119
25	srxa-1	W07A8.1	n/a	chrV 20,728,034	C. elegans SRXA-1 protein; contains similarity to Pfam domain PF03383 Caenorhabditis serpentine receptor-like protein, class xa contains similarity to Interpro domain IPR005047 (Protein of unknown function DUF286, G protein-coupled receptor-like putative Caenorhabditis species)
26	CD4.5	CD4.5	n/a	chrV 5,590,729
27	F22G12.5	F22G12.5	n/a	chrI 13,172,567	contains similarity to Interpro domain IPR001765 (Carbonic anhydrase)
28	F55G7.1	F55G7.1	n/a	chrX 11,925,643	contains similarity to Galleria mellonella Sericin-2 (Silk gum protein 2) (Fragment).; SW:SER2_GALME
29	ZK384.3	ZK384.3	n/a	chrV 18,730,891	contains similarity to Pfam domain PF00026 Eukaryotic aspartyl protease contains similarity to Interpro domains IPR009007 (Peptidase aspartic, catalytic), IPR001412 (Aminoacyl-tRNA synthetase, class I, conserved site), IPR001461 (Peptidase A1)
30	F11A5.4	F11A5.4	n/a	chrV 16,195,957	contains similarity to Pfam domains PF00071 (Ras family) , PF08477 (Miro-like protein) contains similarity to Interpro domains IPR002041 (Ran GTPase), IPR003577 (Ras small GTPase, Ras type), IPR013684 (Miro-like), IPR003578 (Ras small GTPase, Rho type), IPR005225 (Small GTP-binding protein), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR001019 (Guanine nucleotide binding protein (G-protein), alpha subunit), IPR006688 (ADP-ribosylation factor), IPR013753 (Ras)
31	acy-3	C44F1.5	n/a	chrIII 3,778,374	acy-3 encodes a predicted member of the adenylyl cyclase family with highest similarity to human adenylate cyclase type 5; expressed in the support cells of ciliated neurons, in the head and tail ganglia, in two pairs of neurons in the retrovesicular ganglia, and in the spermatheca.
32	T11F1.3	T11F1.3	n/a	chrII 2,955,703
33	Y113G7B.24	Y113G7B.24	n/a	chrV 20,231,897	contains similarity to Pfam domain PF05916 Synthetic lethal mutants of dpb11-1 five contains similarity to Interpro domain IPR008591 (GINS complex, Sld5 component)
34	T27D1.3	T27D1.3	n/a	chrIII 3,684,552	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR008365 (Prostanoid receptor), IPR001991 (Sodium:dicarboxylate symporter), IPR002455 (GPCR, family 3, gamma-aminobutyric acid receptor, type B), IPR000276 (GPCR, rhodopsin-like)
35	C05C10.1	C05C10.1	n/a	chrII 9,918,735	contains similarity to Pfam domain PF00328 Histidine acid phosphatase contains similarity to Interpro domain IPR000560 (Histidine acid phosphatase)
36	C50B8.5	C50B8.5	n/a	chrV 13,582,800	contains similarity to Candida albicans Hypothetical membrane protein.; TR:O94057
37	F16H6.6	F16H6.6	n/a	chrV 18,205,786	contains similarity to Anthyllis vulneraria subsp lapponica Maturase-like protein.; TR:Q8HUG8
38	F14B6.2	F14B6.2	n/a	chrI 12,220,319	contains similarity to Homo sapiens hypothetical protein; ENSEMBL:ENSP00000352916
39	K03H6.5	K03H6.5	n/a	chrIV 1,531,807	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
40	Y37H9A.2	Y37H9A.2	n/a	chrI 13,780,578	contains similarity to Candida albicans Hyphally regulated protein precursor.; SW:HYR1_CANAL
41	sra-30	Y40H7A.6	n/a	chrIV 15,197,622	C. elegans SRA-30 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
42	sfxn-1.1	AH6.2	n/a	chrII 9,518,171	C. elegans SFXN-1.1 protein; contains similarity to Pfam domain PF03820 Tricarboxylate carrier contains similarity to Interpro domain IPR004686 (Tricarboxylate/iron carrier)
43	del-4	T28B8.5	n/a	chrI 8,140,996	C. elegans DEL-4 protein; contains similarity to Pfam domain PF00858 Amiloride-sensitive sodium channel contains similarity to Interpro domain IPR001873 (Na+ channel, amiloride-sensitive)
44	bath-47	T07H3.1	n/a	chrII 1,603,204	C. elegans BATH-47 protein; contains similarity to Pfam domains PF00651 (BTB/POZ domain) (2), PF00917 (MATH domain) (2)contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH), IPR000694 (Proline-rich region), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
45	ist-1	C54D1.3	n/a	chrX 7,135,879	ist-1 encodes a pleckstrin homology (PH) and phosphotyrosine binding (PTB) domain-containing insulin receptor substrate (IRS) homolog that negatively regulates lifespan and dauer development; IST-1 potentiates insulin-like signaling, although it is not absolutely required for such signaling under most conditions; in addition to acting through the AGE-1/PI3K branch of the insulin-like signaling pathway, IST-1 may also function in a parallel pathway to activate downstream protein-kinase Bs encoded by akt-1 and akt-2.
46	C32H11.1	C32H11.1	n/a	chrIV 12,913,842	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domains IPR000859 (CUB), IPR003366 (CUB-like region)
47	Y48A6B.1	Y48A6B.1	n/a	chrIII 10,993,565	contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
48	F32D1.3	F32D1.3	n/a	chrV 4,355,654	contains similarity to Pfam domains PF07719 (Tetratricopeptide repeat) (3), PF08409 (Domain of unknown function (DUF1736)) , PF00515 (Tetratricopeptide repeat) (6)contains similarity to Interpro domains IPR011990 (Tetratricopeptide-like helical), IPR013618 (Region of unknown function DUF1736), IPR008940 (Protein prenyltransferase), IPR001440 (Tetratricopeptide TPR-1), IPR013105 (Tetratricopeptide TPR2), IPR013026 (Tetratricopeptide region)
49	sre-14	C42C1.1	n/a	chrIV 12,260,640	C. elegans SRE-14 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domains IPR000326 (Phosphatidic acid phosphatase type 2/haloperoxidase), IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
50	srd-30	F07C4.5	n/a	chrV 7,630,532	C. elegans SRD-30 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)