UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	H12D21.5	H12D21.5	4e-72	chrV 14,894,419	contains similarity to Interpro domains IPR001307 (Thiosulfate sulfurtransferase), IPR000463 (Cytosolic fatty-acid binding protein), IPR001763 (Rhodanese-like)
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	fbxa-96	H03G16.4	n/a	chrX 15,059,361	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
4	C06C3.9	C06C3.9	n/a	chrII 9,377,271
5	Y41C4A.1	Y41C4A.1	n/a	chrIII 11,648,712	contains similarity to Oryza sativa Putative aspartate kinase.; TR:Q851Z6
6	C56C10.12	C56C10.12	n/a	chrII 6,606,347	contains similarity to Interpro domain IPR016024 (Armadillo-type fold)
7	irk-1	R03E9.4	n/a	chrX 6,769,400	C. elegans IRK-1 protein; contains similarity to Pfam domain PF01007 Inward rectifier potassium channel contains similarity to Interpro domains IPR013521 (Potassium channel, inwardly rectifying, Kir, conserved region 2), IPR014756 (Immunoglobulin E-set), IPR013518 (Potassium channel, inwardly rectifying, Kir, cytoplasmic), IPR001838 (Potassium channel, inwardly rectifying, Kir-like)
8	B0207.1	B0207.1	n/a	chrI 5,966,138	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR000387 (Protein-tyrosine phosphatase), IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR000005 (Helix-turn-helix, AraC type), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000694 (Proline-rich region), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type)
9	try-6	F48A9.3	n/a	chrI 6,586,594	C. elegans TRY-6 protein; contains similarity to Pfam domains PF00089 (Trypsin) , PF03761 (Domain of unknown function (DUF316)) contains similarity to Interpro domains IPR001314 (Peptidase S1A, chymotrypsin), IPR001254 (Peptidase S1 and S6, chymotrypsin/Hap), IPR005514 (Protein of unknown function DUF316), IPR009003 (Peptidase, trypsin-like serine and cysteine)
10	T02G6.2	T02G6.2	n/a	chrI 11,801,906	contains similarity to Arabidopsis thaliana Hypothetical protein.; TR:Q9C9Y9
11	srg-46	F32H5.5	n/a	chrV 13,364,203	C. elegans SRG-46 protein ;
12	F21C3.6	F21C3.6	n/a	chrI 7,284,859	contains similarity to Homo sapiens Isoform 1 of Caldesmon; ENSEMBL:ENSP00000354826
13	T09B4.3	T09B4.3	n/a	chrI 6,177,087
14	sri-36	F33H12.5	n/a	chrII 2,584,688	C. elegans SRI-36 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
15	Y17G7B.19	Y17G7B.19	n/a	chrII 12,110,327	contains similarity to Pfam domain PF01666 (DX module)
16	Y47H9B.2	Y47H9B.2	n/a	chrI 11,745,783	contains similarity to Pfam domain PF03761 Domain of unknown function (DUF316) contains similarity to Interpro domain IPR005514 (Protein of unknown function DUF316)
17	F18A12.4	F18A12.4	n/a	chrII 3,405,348	F18A12.4 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; F18A12.4 has no clear orthologs in other organisms.
18	lgc-30	F58H7.3	n/a	chrIV 932,249	C. elegans LGC-30 protein; contains similarity to Pfam domain PF02931 Neurotransmitter-gated ion-channel ligand binding domain contains similarity to Interpro domains IPR002394 (Nicotinic acetylcholine receptor, N-terminal), IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding)
19	Y51A2D.18	Y51A2D.18	n/a	chrV 18,484,174	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR001991 (Sodium:dicarboxylate symporter), IPR011701 (Major facilitator superfamily MFS-1), IPR005829 (Sugar transporter, conserved site), IPR005828 (General substrate transporter), IPR003663 (Sugar transporter), IPR016196 (MFS general substrate transporter)
20	C03B1.6	C03B1.6	n/a	chrX 6,350,637
21	K10C9.7	K10C9.7	n/a	chrV 1,066,687
22	unc-79	E03A3.6	n/a	chrIII 4,074,729	unc-79 encodes a novel, conserved protein; unc-79 functions in a pathway with nca-1 and nca-2, which encode ion channel subunits, to regulate locomotion and the response to specific volatile anesthetics; unc-79 exerts its effects on these processes, at least in part, by regulating the levels of NCA-1 and NCA-2 proteins; an unc-79::gfp reporter is expressed in the nervous system in ventral nerve cord neurons in L2 and L3 larvae and in one or two head neurons in adults.
23	F36D1.6	F36D1.6	n/a	chrI 11,270,696	contains similarity to Pfam domain PF03761 Domain of unknown function (DUF316) contains similarity to Interpro domains IPR005514 (Protein of unknown function DUF316), IPR009003 (Peptidase, trypsin-like serine and cysteine)
24	Y48E1C.3	Y48E1C.3	n/a	chrII 13,439,410	contains similarity to Pfam domain PF00566 TBC domain contains similarity to Interpro domain IPR000195 (RabGAP/TBC)
25	srz-45	Y6G8.1	n/a	chrV 17,593,282	C. elegans SRZ-45 protein; contains similarity to Interpro domain IPR002229 (Blood group Rhesus C/E and D polypeptide)
26	ZK1290.10	ZK1290.10	n/a	chrII 7,552,859	contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR003582 (Metridin-like ShK toxin)
27	Y18D10A.3	Y18D10A.3	n/a	chrI 12,812,894	contains similarity to Pfam domain PF03853 YjeF-related protein N-terminus contains similarity to Interpro domain IPR004443 (YjeF-related protein, N-terminal)
28	F54D12.7	F54D12.7	n/a	chrII 1,383,599	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domain IPR006583 (CW)
29	str-86	F59E11.14	n/a	chrV 8,983,013	C. elegans STR-86 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
30	F11D5.5	F11D5.5	n/a	chrX 3,302,988	contains similarity to Interpro domain IPR016196 (MFS general substrate transporter)
31	F46B6.10	F46B6.10	n/a	chrV 9,801,717	contains similarity to Homo sapiens Hypothetical protein; TR:Q96QJ8
32	tag-19	C09G9.4	n/a	chrIV 8,875,605	tag-19 superficially resembles aromatic-L-amino-acid/L-histidine decarboxylases; however, it is distantly related, being no closer to them than to glutamine decarboxylase/sphingosinge lyase (e.g., tag-38, spl-1); tag-19 thus might be termed a Pyridoxal-phosphate (PLP) dependent decarboxylase-like protei, but is missing the absolutely conserved Lys residue of all PLP-DCs (hence the -like would be needed); tag-19 is dispensable in mass RNAi assays.
33	T20H4.2	T20H4.2	n/a	chrIII 7,242,074	contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
34	Y57G11C.23	Y57G11C.23	n/a	chrIV 14,858,495	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005828 (General substrate transporter), IPR016196 (MFS general substrate transporter)
35	F23C8.8	F23C8.8	n/a	chrI 2,431,177	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
36	grl-2	T16G1.8	n/a	chrV 12,945,836	grl-2 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central proline-rich low-complexity region, and a C-terminal Ground-like (Grl) domain; GRL-2 is expressed in neurons, amphid socket cells, and other cells; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
37	E03H4.12	E03H4.12	n/a	chrI 12,436,494	contains similarity to Pfam domain PF03360 Glycosyltransferase family 43 contains similarity to Interpro domain IPR005027 (Glycosyl transferase, family 43)
38	W05B5.1	W05B5.1	n/a	chrI 13,043,893	contains similarity to Saccharomyces cerevisiae Homolog of human WASP, proline-rich protein; SGD:YOR181W
39	C44F1.2	C44F1.2	n/a	chrIII 3,769,375	contains similarity to Pfam domains PF01342 (SAND domain) , PF02178 (AT hook motif) contains similarity to Interpro domains IPR000637 (HMG-I and HMG-Y, DNA-binding), IPR010919 (SAND-like), IPR000770 (SAND)
40	F47F6.4	F47F6.4	n/a	chrII 1,262,570
41	srt-44	M199.1	n/a	chrIV 15,105,017	C. elegans SRT-44 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
42	ndx-2	W02G9.1	n/a	chrV 2,664,041	ndx-2 encodes a NUDIX hydrolase; by sequence comparison, NDX-2 is predicted to be orthologous to human NUDT5 which, in vitro, possesses ADP-sugar diphosphatase activity; in C. elegans, loss of ndx-2 activity via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, consistent with the proposed nonessential roles for Nudix proteins in eliminating potentially toxic nucleotide metabolites from cells and modulating levels of metabolic intermediates by shuttling them into alternative biochemical pathways.
43	abt-3	F55G11.9	n/a	chrIV 12,953,691	abt-3 encodes a predicted ATP-binding cassette (ABC) transporter that is a member of the ABCA subfamily of transport proteins; ABT-3 is predicted to function as a transmembrane protein that couples energy to transport of various molecules across membranes, but as loss of abt-3 activity via RNAi results in no obvious defects, the precise role of abt-3 in C. elegans development and/or behavior is not yet known.
44	F49C12.1	F49C12.1	n/a	chrIV 9,295,603	contains similarity to Pfam domain PF03407 Protein of unknown function (DUF271) contains similarity to Interpro domain IPR005069 (Protein of unknown function DUF271)
45	M70.4	M70.4	n/a	chrIV 2,258,333	M70.4 is orthologous to human O-MANNOSE BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE (FLJ20277; OMIM:606822), which when mutated leads to muscle-eye-brain disease.
46	sru-22	F36G9.5	n/a	chrV 15,973,922	C. elegans SRU-22 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
47	C56A3.3	C56A3.3	n/a	chrV 13,533,300	C56A3.3 encodes a homolog of the functionally active Fmrf Receptor (FR; CG2114) of D. melanogaster; it is thus possible that C56A3.3 is a receptor for one of the FMRF-like neurotransmitters in C. elegans (e.g., FLP-1 through FLP-12).
48	ZC404.7	ZC404.7	n/a	chrV 6,779,108
49	C33E10.6	C33E10.6	n/a	chrX 17,268,242	contains similarity to Tetrahymena thermophila SB210 Putative uncharacterized protein.; TR:Q227I5
50	T06E4.5	T06E4.5	n/a	chrV 9,631,723	contains similarity to Interpro domains IPR001046 (Natural resistance-associated macrophage protein), IPR001266 (Ribosomal protein S19e)