UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	H10E21.5	H10E21.5	0	chrIII 22,248	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011016 (Zinc finger, variant RING-type)
2	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
3	C30F12.6	C30F12.6	n/a	chrI 6,990,585	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR008365 (Prostanoid receptor), IPR002120 (Thyrotrophin-releasing hormone receptor), IPR009144 (Thyrotropin-releasing hormone receptor), IPR000276 (GPCR, rhodopsin-like)
4	mec-18	C52B9.9	n/a	chrX 4,272,688	mec-18 encodes a protein similar to firefly luciferase and plant protein 4-coumarate coA ligase; mec-18 is involved in sensory mechanotransduction; genetic interactions with other mec genes suggest that mec-18 may be involved in negative regulation of the degenerin channel in the touch receptor neurons; mec-18 is expressed exclusively in the touch cells.
5	clec-89	C09D1.2	n/a	chrI 4,072,314	C. elegans CLEC-89 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR003990 (Pancreatitis-associated protein), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
6	ZC416.1	ZC416.1	n/a	chrIV 3,637,332	n/a
7	cwp-4	K11D12.1	n/a	chrV 5,055,031	cwp-4 encodes a protein with some similarity to mucins that is predicted to be secreted, and is alleged to be coexpressed with polycystins; CWP-4 is dispensable for viability and gross morphology in mass RNAi screens.
8	pgp-12	F22E10.1	n/a	chrX 12,734,558	pgp-12 encodes a transmembrane protein that is a member of the P-glycoprotein subclass of ATP-binding cassette (ABC) transporters; although loss of pgp-12 function via mutation or RNAi results in no obvious defects, pgp-12 promoter fusion constructs reveal expression in the excretory cell, consistent with a role for pgp-12 in metabolite transporter activity; pgp-12 expression is regulated by the DCP-66 transcription factor which binds the pgp-12 Ex-1 promoter element in yeast one-hybrid and EMSA experiments.
9	F15A2.7	F15A2.7	n/a	chrX 13,489,900	contains similarity to Xanthomonas campestris Exodeoxyribonuclease V beta chain.; TR:Q8P379
10	C18B2.3	C18B2.3	n/a	chrX 3,603,031
11	ctl-1	Y54G11A.6	n/a	chrII 14,304,828	ctl-1 encodes one of three C. elegans catalases; CTL-1 exhibits catalase activity in vitro, and thus likely functions in vivo as an antioxidant enzyme that protects cells from reactive oxygen species; ctl-1 activity contributes to the extended lifespan seen in daf-2 mutant animals; in addition, ctl-1 expression is negatively regulated by DAF-2-mediated insulin signaling; as CTL-1 does not possess a C-terminal peroxisomal targeting signal (PTS), it is predicted to be a cytosolic catalase.
12	atg-11	T08A9.1	n/a	chrX 7,337,446	T08A9.1 is orthologous to the human gene LIKELY ORTHOLOG OF MOUSE COILED COIL FORMING PROTEIN 1 (RB1CC1; OMIM:606837), which when mutated leads to disease.
13	F55C12.4	F55C12.4	n/a	chrII 5,857,731
14	ZC581.9	ZC581.9	n/a	chrI 6,667,794	ZC581.9 encodes a serine/threonine protein kinase related to the vertebrate SCY1-like family of protein kinases; loss of ZC581.9 activity in an RNAi-hypersensitive strain results in axon guidance defects indicating that ZC581.9 likely plays a role in regulation of axon navigation.
15	ndx-1	T26E3.2	n/a	chrI 12,680,484	The ndx-1 gene encodes a NUDIX hydrolase.
16	ZC190.5	ZC190.5	n/a	chrV 8,672,433
17	T14C1.1	T14C1.1	n/a	chrX 14,408,600	T14C1.1 encodes a homolog of the functionally active Fmrf Receptor (FR; CG2114) of D. melanogaster; it is thus possible that T14C1.1 is a receptor for one of the FMRF-like neurotransmitters in C. elegans (e.g., FLP-1 through FLP-12).
18	C25E10.4	C25E10.4	n/a	chrV 9,034,575	contains similarity to Interpro domains IPR000802 (Arsenical pump membrane protein), IPR016196 (MFS general substrate transporter)
19	K10C8.2	K10C8.2	n/a	chrV 12,691,417	K10C8.2 encodes a homolog of the functionally active Fmrf Receptor (FR; CG2114) of D. melanogaster; it is thus possible that K10C8.2 is a receptor for one of the FMRF-like neurotransmitters in C. elegans (e.g., FLP-1 through FLP-12).
20	C29F9.6	C29F9.6	n/a	chrIII 115,990	contains similarity to Pfam domain PF02135 TAZ zinc finger contains similarity to Interpro domains IPR003101 (Coactivator CBP, KIX), IPR000197 (Zinc finger, TAZ-type)
21	T05H10.3	T05H10.3	n/a	chrII 8,049,736
22	C07B5.2	C07B5.2	n/a	chrX 9,516,733	contains similarity to Listeria monocytogenes Probable tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferases(EC 2.1.1.61).; SW:TRMU_LISMO
23	glr-5	ZC196.7	n/a	chrV 8,718,671	glr-5 encodes a kainate (non-NMDA)-type ionotropic glutamate receptor subunit; GLR-5 activity is required for normal brood sizes, especially at high temperatures; GLR-5 is expressed in neurons.
24	F34D10.6	F34D10.6	n/a	chrIII 3,756,086	contains similarity to Pfam domain PF00023 Ankyrin repeat contains similarity to Interpro domain IPR002110 (Ankyrin)
25	daf-14	F01G10.8	n/a	chrIV 10,254,701	daf-14 encodes a Smad-related protein that is unusual in that while its C-terminus is well-conserved with Smad proteins, it lacks the N-terminal DNA binding domain found in all other known Smads; DAF-14 is predicted to function as a transducer of the DAF-7/TGF-beta-mediated signal that promotes reproductive growth and negatively regulates dauer formation; as reduction of daf-14 function enhances the dauer constitutive phenotype of daf-8 mutants, and overexpression of daf-14 can rescue daf-8 mutant animals, it is likely that the DAF-14 and DAF-8 Smad proteins function in parallel to control dauer formation; further genetic analyses suggest that DAF-14 and DAF-8 function to antagonize the activities of the DAF-3 Smad and DAF-5 Sno/Ski oncoprotein, which are required for dauer formation; a DAF-14::GFP reporter is expressed in a dynamic pattern in tissues, such as the hypodermis, intestine, and pharynx, that are remodeled during dauer development.
26	glb-3	C06H2.5	n/a	chrV 11,139,410	glb-3 encodes a globin with no obvious function in mass RNAi assays.
27	C53A5.13	C53A5.13	n/a	chrV 14,550,708	contains similarity to Pfam domain PF00041 Fibronectin type III domain contains similarity to Interpro domains IPR008957 (Fibronectin, type III-like fold), IPR003961 (Fibronectin, type III), IPR003962 (Fibronectin, type III subdomain)
28	C05E7.3	C05E7.3	n/a	chrX 12,946,010	contains similarity to Triticum aestivum Cold acclimation protein WCOR410b.; TR:P93607
29	C25F9.6	C25F9.6	n/a	chrV 19,405,134	contains similarity to Ectromelia virus EVM128.; TR:Q8JL89
30	ZC84.3	ZC84.3	n/a	chrIII 9,188,742	contains similarity to Pfam domain PF02985 HEAT repeat contains similarity to Interpro domains IPR000357 (HEAT), IPR016024 (Armadillo-type fold)
31	lev-1	F09E8.7	n/a	chrIV 13,176,746	lev-1 encodes an alpha subunit of nicotinic acetylcholine receptor (nAChR) which, when mutated, confers resistance to levamisole; LEV-1 is required for completely normal locomotion, and forms a cation channel when coexpressed with UNC-38 or UNC-63 and UNC-29; LEV-1 falls into the 'UNC-29' class of nAChR subunits, which includes UNC-29, ACR-2, and ACR-3.
32	C04E6.8	C04E6.8	n/a	chrV 5,883,601
33	R02F2.8	R02F2.8	n/a	chrIII 5,494,067	contains similarity to Pfam domain PF01490 Transmembrane amino acid transporter protein contains similarity to Interpro domains IPR002091 (Aromatic amino acid permease), IPR013057 (Amino acid transporter, transmembrane)
34	T22B2.6	T22B2.6	n/a	chrX 3,915,288
35	F23A7.5	F23A7.5	n/a	chrX 16,233,076	contains similarity to Homo sapiens Isoform 3 of Cyclin-L1; VG:OTTHUMP00000173336
36	Y43F8A.5	Y43F8A.5	n/a	chrV 19,387,467	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
37	srh-261	K03D7.4	n/a	chrV 17,498,163	C. elegans SRH-261 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
38	F21C10.9	F21C10.9	n/a	chrV 9,097,952	contains similarity to Interpro domains IPR000182 (GCN5-related N-acetyltransferase), IPR016181 (Acyl-CoA N-acyltransferase)
39	DC2.5	DC2.5	n/a	chrV 211,433	contains similarity to Pfam domain PF00439 Bromodomain contains similarity to Interpro domain IPR001487 (Bromodomain)
40	trpa-1	C29E6.2	n/a	chrIV 11,870,347	trpa-1 encodes a transient receptor potential (TRP) ion channel orthologous to the vertebrate and Drosophila TRPA1 channels; in C. elegans, trpa-1 activity is required for specific mechanosensory behaviors such as nose-touch avoidance and touch-mediated foraging; when expressed in mammalian cells, TRPA-1 exhibits channel activity in response to mechanical stimulation; TRPA-1::GFP reporters are expressed in a number of different cell types including sensory neurons, muscle, and epithelial cells.
41	K08E7.6	K08E7.6	n/a	chrIV 12,580,060	contains similarity to Aquifex aeolicus Probable DNA double-strand break repair rad50 ATPase.; SW:RA50_AQUAE
42	AC8.4	AC8.4	n/a	chrX 227,022
43	F45E1.2	F45E1.2	n/a	chrX 8,003,850
44	elt-3	K02B9.4	n/a	chrX 13,939,895	The elt-3 gene encodes a GATA transcription factor expressed in the embryonic hypodermis; specifically, it is expressed in expressed in all of the major hypodermal cells except the lateral seam cells.
45	C32E8.11	C32E8.11	n/a	chrI 3,812,136	contains similarity to Pfam domains PF02617 (ATP-dependent Clp protease adaptor protein ClpS) , PF02207 (Putative zinc finger in N-recognin (UBR box)) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013993 (Zinc finger, N-recognin, metazoa), IPR014719 (Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like), IPR003126 (Zinc finger, N-recognin), IPR000315 (Zinc finger, B-box), IPR003769 (Adaptor protein ClpS, core)
46	ncs-3	K03E6.3	n/a	chrX 1,055,449	ncs-3 encodes a neuronal calcium sensor (NCS) protein with no obvious null phenotype.
47	F25D1.3	F25D1.3	n/a	chrV 10,529,632	contains similarity to Pfam domain PF06083 Interleukin-17 contains similarity to Interpro domain IPR010345 (Interleukin-17)
48	F25E5.2	F25E5.2	n/a	chrV 7,456,619	contains similarity to Pfam domain PF04590 Protein of unknown function, DUF595 contains similarity to Interpro domain IPR007669 (Protein of unknown function DUF595)
49	T09F3.1	T09F3.1	n/a	chrII 10,386,641	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR003656 (Zinc finger, BED-type predicted), IPR007087 (Zinc finger, C2H2-type)
50	R13H4.7	R13H4.7	n/a	chrV 11,867,399	contains similarity to Interpro domain IPR000276 (GPCR, rhodopsin-like)