UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	ver-3	F59F3.1	0	chrX 10,995,095	C. elegans VER-3 protein; contains similarity to Pfam domains PF07686 (Immunoglobulin V-set domain) (2), PF00047 (Immunoglobulin domain) (4), PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) , PF07679 (Immunoglobulin I-set domain) contains similarity to Interpro domains IPR003598 (Immunoglobulin subtype 2), IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR013098 (Immunoglobulin I-set), IPR011009 (Protein kinase-like), IPR003596 (Immunoglobulin V-set, subgroup), IPR013783 (Immunoglobulin-like fold), IPR000719 (Protein kinase, core), IPR013106 (Immunoglobulin V-set), IPR007110 (Immunoglobulin-like), IPR003599 (Immunoglobulin subtype), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR008266 (Tyrosine protein kinase, active site), IPR013151 (Immunoglobulin)
2	ZK632.7	ZK632.7	n/a	chrIII 9,821,105	contains similarity to Interpro domain IPR011009 (Protein kinase-like)
3	R03C1.1	R03C1.1	n/a	chrII 14,908,902	contains similarity to Homo sapiens Mucin-5AC precursor (Fragment); ENSEMBL:ENSP00000351148
4	cul-1	D2045.6	n/a	chrIII 10,473,304	cul-1 encodes a cullin, orthologous to Cdc53/Cul1 in S. cerevisiae and CUL-1 in humans (OMIM:603134), that is required both maternally and zygotically for developmentally programmed transitions from the G1 phase of the cell cycle to the GO phase or the apoptotic pathway, and that is probably also required for normally slow G1-to-S phase progression; CUL-1 physically interacts with eight Skp1-related proteins (SKR-1, -2, -3, -4, -7, -8, -9, and -10).
5	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
6	srx-105	F40H7.8	n/a	chrII 3,700,613	C. elegans SRX-105 protein ;
7	ctg-2	T13H5.2	n/a	chrII 8,515,897	C. elegans CTG-2 protein; contains similarity to Pfam domains PF01105 (emp24/gp25L/p24 family/GOLD) , PF00650 (CRAL/TRIO domain) contains similarity to Interpro domains IPR001071 (Cellular retinaldehyde binding/alpha-tocopherol transport), IPR001251 (Cellular retinaldehyde-binding/triple function, C-terminal), IPR009038 (GOLD), IPR011074 (Phosphatidylinositol transfer protein-like, N-terminal), IPR000348 (emp24/gp25L/p24)
8	mep-1	M04B2.1	n/a	chrIV 11,526,270	mep-1 is required for repression by the fem-3 3' UTR in vivo, and for maintenance of somatic (versus germline) differentiation; MEP-1 protein has zinc-finger domains and a glutamine/asparagine-rich domain.
9	clh-5	C07H4.2	n/a	chrII 9,096,575	The clh-5 gene encodes a chloride channel, whose human homologs include CLC1 and CLCN5; the latter homolog is imvolved in receptor-mediated endocytosis.
10	C06B8.7	C06B8.7	n/a	chrV 15,505,052	contains similarity to Pfam domain PF00530 Scavenger receptor cysteine-rich domain contains similarity to Interpro domains IPR002160 (Proteinase inhibitor I3, Kunitz legume), IPR001190 (Speract/scavenger receptor), IPR011050 (Pectin lyase fold/virulence factor), IPR006626 (Parallel beta-helix repeat), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin), IPR017448 (Speract/scavenger receptor related)
11	sec-8	Y106G6H.7	n/a	chrI 10,449,365	The sec-8 gene encodes an ortholog of SEC8 in S. cerevisiae, a component of the exocyst complex required genetically for endocytosis, for normal cellular morphology in the intestine, and for growth at normal rates during development.
12	F17A9.3	F17A9.3	n/a	chrV 6,106,582	contains similarity to Pfam domain PF07716 Basic region leucine zipper contains similarity to Interpro domains IPR011700 (Basic leucine zipper), IPR004827 (Basic-leucine zipper (bZIP) transcription factor)
13	Y8A9A.3	Y8A9A.3	n/a	chrII 3,791,812	contains similarity to Interpro domain IPR009071 (High mobility group box, HMG)
14	F21G4.6	F21G4.6	n/a	chrX 9,913,063	F21G4.6 is orthologous to the human gene HUNTINGTIN (HD; OMIM:143100), which when mutated leads to disease.
15	fbf-2	F21H12.5	n/a	chrII 6,090,134	fbf-2 encodes an RNA-binding protein that is one of 11 C. elegans members of the PUF family (Pumilio and FBF) of translational regulators; FBF-2 is nearly identical to FBF-1 with which it is largely redundant in regulating two aspects of germline development: 1)maintenance of stem cell proliferation, and 2)the hermaphroditic switch between spermatogenesis and oogenesis; in maintaining germline stem cells, the FBF proteins, acting through NOS-3, negatively regulate the activity of gld-1 mRNA, which encodes a translational repressor required for meiotic entry; in regulating the sperm-to-oocyte switch, the FBFs act downstream of GLD-3 to negatively regulate the activity of fem-3 mRNA, which encodes a novel protein required for germline sex determination; consistent with their role in germline development, FBF-1 and FBF-2 are expressed in the germline cytoplasm, becoming enriched in the mitotic region during the L4 larval and adult stages.
16	prx-11	C47B2.8	n/a	chrI 12,971,925	C. elegans PRX-11 protein ; contains similarity to Homo sapiens Isoform 1 of Peroxisomal membrane protein 11C; ENSEMBL:ENSP00000221480
17	C53C11.4	C53C11.4	n/a	chrX 17,310,975	contains similarity to Pfam domain PF05671 GETHR pentapeptide repeat (5 copies) contains similarity to Interpro domains IPR002275 (GPR1 orphan receptor), IPR008627 (GETHR pentapeptide)
18	fipr-15	F13E9.3	n/a	chrIV 10,880,611	C. elegans FIPR-15 protein; contains similarity to Interpro domain IPR005137 (Photosystem I assembly BtpA)
19	B0478.3	B0478.3	n/a	chrIV 6,964,202	contains similarity to Interpro domains IPR013090 (Phospholipase A2, active site), IPR016090 (Phospholipase A2), IPR001211 (Phospholipase A2, eukaryotic)
20	nas-36	C26C6.3	n/a	chrI 7,529,499	nas-36 encodes an astacin-like protease; nas-36 activity is required for molting; a nas-36::gfp reporter is expressed in hypodermal cells.
21	sdc-3	C25D7.3	n/a	chrV 15,043,550	sdc-3 encodes a protein that contains two mutationally separable domains: a zinc finger motif required for dosage compensation and a myosin- like putative ATP- binding region required for her-1 regulation of sex determination; SDC-3 activates dosage compensation by directing the dosage compensation protein complex to the hermaphrodite X chromosomes, and is functionally redundant with SDC-2 with respect to dosage compensation; SDC-1, SDC-2, and SDC-3 proteins form a complex.
22	alh-2	K04F1.15	n/a	chrV 1,646,053	C. elegans ALH-2 protein; contains similarity to Pfam domain PF00171 Aldehyde dehydrogenase family contains similarity to Interpro domains IPR016163 (Aldehyde dehydrogenase, C-terminal), IPR016162 (Aldehyde dehydrogenase, N-terminal), IPR016161 (Aldehyde/histidinol dehydrogenase), IPR015590 (Aldehyde dehydrogenase), IPR016160 (Aldehyde dehydrogenase, conserved site)
23	ger-1	R01H2.5	n/a	chrIII 7,066,371	C. elegans GER-1 protein; contains similarity to Pfam domain PF01370 NAD dependent epimerase/dehydratase family contains similarity to Interpro domains IPR001509 (NAD-dependent epimerase/dehydratase), IPR002347 (Glucose/ribitol dehydrogenase), IPR016040 (NAD(P)-binding)
24	dnc-1	ZK593.5	n/a	chrIV 10,929,896	DNC-1 encodes a dynactin, orthologous to Drosophila GLUED, that is required for pronuclear migration and centrosome separation in one-cell embryos and for the correct alignment of mitotic spindles in early embryos; DNC-1 shares embryonic functions with DNC-2, DHC-1, LIS-1 and NUD-1; DNC-1 is located at cortical microtubule attachment sites.
25	dpy-26	C25G4.5	n/a	chrIV 12,448,610	dpy-26 encodes a novel, acidic protein that is highly conserved in other Caenorhabditis species; during development, dpy-26 activity is required for both dosage compensation and meiotic chromosome segregation; DPY-26 localizes to all meiotic chromosomes in the germline and to the hermaphrodite X chromosomes in somatic cells; SDC-1, SDC-2, and SDC-3 proteins form a complex and these three proteins, in turn, colocalize with DPY-26, DPY-27, and MIX-1 proteins both on the X chromosome and on a transgenic her-1(+) array.
26	F08G12.1	F08G12.1	n/a	chrX 11,303,901	contains similarity to Pfam domains PF00071 (Ras family) , PF08477 (Miro-like protein) contains similarity to Interpro domains IPR003577 (Ras small GTPase, Ras type), IPR013684 (Miro-like), IPR003578 (Ras small GTPase, Rho type), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR013753 (Ras)
27	Y43F8C.8	Y43F8C.8	n/a	chrV 19,644,963	contains similarity to Drosophila melanogaster Flybase gene name is mRpS28-PA;; FLYBASE:CG5497
28	Y45G12B.3	Y45G12B.3	n/a	chrV 2,691,488	contains similarity to Pfam domain PF01266 FAD dependent oxidoreductase contains similarity to Interpro domains IPR006076 (FAD dependent oxidoreductase), IPR000447 (FAD-dependent glycerol-3-phosphate dehydrogenase), IPR016040 (NAD(P)-binding)
29	T05F1.9	T05F1.9	n/a	chrI 9,646,642	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8ILP3
30	M03C11.3	M03C11.3	n/a	chrIII 10,409,775	contains similarity to Saccharomyces cerevisiae Essential protein required for the maturation of 25S rRNA and 60S ribosomal subunit assembly, localizes to the nucleolus; SGD:YKL172W
31	F18H3.4	F18H3.4	n/a	chrX 13,530,481	contains similarity to Mus musculus GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).; SW:Q8VD04
32	sre-27	Y57A10C.3	n/a	chrII 12,416,469	C. elegans SRE-27 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
33	T19C3.2	T19C3.2	n/a	chrIII 616,074
34	K10B2.4	K10B2.4	n/a	chrII 6,360,595	contains similarity to Pfam domain PF03669 Uncharacterised protein family (UPF0139) contains similarity to Interpro domain IPR005351 (Protein of unknown function UPF0139)
35	M03C11.8	M03C11.8	n/a	chrIII 10,432,042	contains similarity to Pfam domains PF00271 (Helicase conserved C-terminal domain) , PF00176 (SNF2 family N-terminal domain) contains similarity to Interpro domains IPR002048 (Calcium-binding EF-hand), IPR000330 (SNF2-related), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
36	Y59C2A.3	Y59C2A.3	n/a	chrII 2,217,700	contains similarity to Tetrahymena thermophila SB210 Putative uncharacterized protein.; TR:Q22WK5
37	F33H2.5	F33H2.5	n/a	chrI 15,009,733	contains similarity to Pfam domains PF00136 (DNA polymerase family B) , PF03104 (DNA polymerase family B, exonuclease domain) , PF08490 (Domain of unknown function (DUF1744)) contains similarity to Interpro domains IPR006055 (Exonuclease), IPR006172 (DNA-directed DNA polymerase, family B), IPR006133 (DNA-directed DNA polymerase, family B, exonuclease), IPR006134 (DNA-directed DNA polymerase, family B, conserved region), IPR013697 (Region of unknown function DUF1744), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
38	K02F3.2	K02F3.2	n/a	chrIII 848,051	The K02F3.2 gene encodes a homolog of human SLC25A13, which when mutated leads to adult onset type II citrullinaemia (OMIM:603471).
39	B0285.1	B0285.1	0.00003	chrIII 4,336,901	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR000694 (Proline-rich region)
40	F16H11.1	F16H11.1	n/a	chrX 4,670,622	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
41	C15B12.1	C15B12.1	n/a	chrX 6,477,878	contains similarity to Pfam domain PF01266 FAD dependent oxidoreductase contains similarity to Interpro domains IPR006076 (FAD dependent oxidoreductase), IPR000447 (FAD-dependent glycerol-3-phosphate dehydrogenase), IPR016040 (NAD(P)-binding)
42	T08A11.2	T08A11.2	n/a	chrIII 4,266,506	T08A11.2 encodes the C. elegans ortholog of splicing factor 3b subunit 1, also known as SAP155; by homology, the product of T08A11.2 is predicted to be a component of the U2 snRNP that is required for pre-mRNA splicing; large-scale RNAi assays indicate that T08A11.2 activity is essential for a number of processes including embryonic development, normal adult lifespan, vulval morphogenesis, locomotion, and transgene expression and localization.
43	F10D11.6	F10D11.6	n/a	chrI 8,448,214	contains similarity to Pfam domains PF02886 (LBP / BPI / CETP family, C-terminal domain) , PF01273 (LBP / BPI / CETP family, N-terminal domain) contains similarity to Interpro domain IPR001124 (Lipid-binding serum glycoprotein)
44	mtx-1	F39B2.11	n/a	chrI 14,755,776	C. elegans MTX-1 protein; contains similarity to Interpro domains IPR017410 (Metaxin), IPR010987 (Glutathione S-transferase, C-terminal-like)
45	Y37E11B.5	Y37E11B.5	n/a	chrIV 3,596,256	contains similarity to Pfam domains PF01207 (Dihydrouridine synthase (Dus)) , PF00642 (Zinc finger C-x8-C-x5-C-x3-H type (and similar)) (2)contains similarity to Interpro domains IPR000571 (Zinc finger, CCCH-type), IPR013785 (Aldolase-type TIM barrel), IPR001269 (Dihydrouridine synthase, DuS)
46	T22C1.6	T22C1.6	n/a	chrI 7,944,147	contains similarity to Homo sapiens Alpha-taxilin; ENSEMBL:ENSP00000362711
47	ZK1321.1	ZK1321.1	n/a	chrII 9,754,525	contains similarity to Sulfolobus sp NOB8H2 Hypothetical protein.; TR:O93705
48	C13C4.5	C13C4.5	n/a	chrV 12,116,190	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
49	F22E5.11	F22E5.11	n/a	chrII 2,644,695	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
50	Y37D8A.10	Y37D8A.10	n/a	chrIII 12,875,275	contains similarity to Pfam domain PF06703 Microsomal signal peptidase 25 kDa subunit (SPC25) contains similarity to Interpro domain IPR009582 (Microsomal signal peptidase 25 kDa subunit)