UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F59E11.5	F59E11.5	1.0000000000000001e-125	chrV 8,995,696
2	sra-25	T26E3.9	n/a	chrI 12,687,150	C. elegans SRA-25 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domains IPR003945 (NADH-plastoquinone oxidoreductase, chain 5), IPR000344 (Nematode chemoreceptor, Sra)
3	C18A11.3	C18A11.3	n/a	chrX 8,063,304
4	Y48E1B.8	Y48E1B.8	n/a	chrII 13,587,287	contains similarity to Pfam domain PF03407 Protein of unknown function (DUF271) contains similarity to Interpro domain IPR005069 (Protein of unknown function DUF271)
5	vrs-1	ZC513.4	n/a	chrV 8,033,348	vrs-1 encodes a predicted valyl-tRNA synthetase that affects embryonic viability, growth, and morphology
6	cyp-35A2	C03G6.15	n/a	chrV 7,363,242	C. elegans CYP-35A2 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV)
7	fbxa-64	T28A11.21	n/a	chrV 3,277,607	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
8	pas-2	D1054.2	n/a	chrV 10,770,774	pas-2 encodes a proteasome subunit with highest similarity to vertebrate proteasome alpha 2 subunits.
9	pas-4	C36B1.4	n/a	chrI 8,727,906	pas-4 encodes a proteasome alpha-type seven subunit of the core 20S proteasome subcomplex; loss of pas-4 activity via RNAi results in a wide variety of defects including embryonic and larval lethality, sterility, abnormal locomotion, slow growth, and abnormal transgene expression and subcellular localization; loss of pas-4 activity also results in activation of SKN-1, a transcription factor required in adult worms for the acute response to oxidative stress and maternally for embryonic development.
10	nud-1	F53A2.4	n/a	chrIII 13,341,947	nud-1 encodes the C. elegans ortholog of the Aspergillus nidulans nudC, which mediates nuclear migration along Aspergillus hyphae.
11	frs-2	F22B5.9	n/a	chrII 8,465,894	C. elegans FRS-2 protein; contains similarity to Pfam domains PF03483 (B3/4 domain) , PF03484 (tRNA synthetase B5 domain) contains similarity to Interpro domains IPR009061 (Putative DNA binding), IPR004531 (Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic), IPR005146 (B3/B4 tRNA-binding domain), IPR005147 (tRNA synthetase, B5)
12	rps-25	K02B2.5	n/a	chrIV 5,947,351	rps-25 encodes a small ribosomal subunit S25 protein.
13	F25B4.1	F25B4.1	n/a	chrV 5,713,763	F25B4.1 is orthologous to the human gene GLYCINE CLEAVAGE SYSTEM T-PROTEIN (AMT; OMIM:238310), which when mutated leads to glycine encephalopathy.
14	M03B6.1	M03B6.1	n/a	chrX 13,842,218
15	K06A5.6	K06A5.6	n/a	chrI 6,465,004	contains similarity to Pfam domains PF08028 (Acyl-CoA dehydrogenase, C-terminal domain) , PF02770 (Acyl-CoA dehydrogenase, middle domain) , PF00441 (Acyl-CoA dehydrogenase, C-terminal domain) , PF02771 (Acyl-CoA dehydrogenase, N-terminal domain) contains similarity to Interpro domains IPR013107 (Acyl-CoA dehydrogenase, type 2, C-terminal), IPR006090 (Acyl-CoA oxidase/dehydrogenase, type 1), IPR013786 (Acyl-CoA dehydrogenase/oxidase, N-terminal), IPR006091 (Acyl-CoA dehydrogenase/oxidase, central region), IPR006089 (Acyl-CoA dehydrogenase, conserved site), IPR013764 (Acyl-CoA oxidase/dehydrogenase, type1/2, C-terminal), IPR009100 (Acyl-CoA dehydrogenase/oxidase, middle and N-terminal), IPR006092 (Acyl-CoA dehydrogenase, N-terminal)
16	F52D1.1	F52D1.1	n/a	chrX 463,783	contains similarity to Pfam domain PF01055 Glycosyl hydrolases family 31 contains similarity to Interpro domains IPR017853 (Glycoside hydrolase, catalytic core), IPR000322 (Glycoside hydrolase, family 31)
17	ugt-48	C18C4.3	n/a	chrV 5,546,863	C. elegans UGT-48 protein; contains similarity to Pfam domains PF04101 (Glycosyltransferase family 28 C-terminal domain) , PF00201 (UDP-glucoronosyl and UDP-glucosyl transferase) contains similarity to Interpro domains IPR001412 (Aminoacyl-tRNA synthetase, class I, conserved site), IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase), IPR007235 (Glycosyl transferase, family 28, C-terminal)
18	C26E6.6	C26E6.6	n/a	chrIII 4,936,354	contains similarity to Pfam domain PF00297 Ribosomal protein L3 contains similarity to Interpro domains IPR009000 (Translation elongation and initiation factors/Ribosomal, beta-barrel), IPR000597 (Ribosomal protein L3)
19	ZK856.5	ZK856.5	n/a	chrV 10,187,411	contains similarity to Pfam domain PF00149 Calcineurin-like phosphoesterase contains similarity to Interpro domain IPR004843 (Metallophosphoesterase)
20	tag-210	W08E3.3	n/a	chrI 13,342,122	C. elegans TAG-210 protein; contains similarity to Pfam domains PF01926 (GTPase of unknown function) , PF06071 (Protein of unknown function (DUF933)) contains similarity to Interpro domains IPR012675 (Beta-grasp fold, ferredoxin-type), IPR013029 (Protein of unknown function DUF933), IPR004396 (Conserved hypothetical protein CHP00092), IPR002917 (GTP-binding protein, HSR1-related), IPR012676 (TGS-like), IPR006073 (GTP1/OBG)
21	rpl-36	F37C12.4	n/a	chrIII 7,180,363	rpl-36 encodes a large ribosomal subunit L36 protein; by homology, RPL-36 is predicted to function in protein biosynthesis; in C. elegans, RPL-36 activity is required for embryonic and germline development and normal postembryonic growth rates.
22	tag-257	F46G11.3	n/a	chrX 5,784,865	C. elegans TAG-257 protein; contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
23	pcp-1	ZK112.1	n/a	chrIII 7,759,923	C. elegans PCP-1 protein; contains similarity to Pfam domain PF05577 Serine carboxypeptidase S28 contains similarity to Interpro domain IPR008758 (Peptidase S28)
24	B0286.3	B0286.3	n/a	chrII 4,371,091	contains similarity to Pfam domains PF01259 (SAICAR synthetase) , PF00731 (AIR carboxylase) contains similarity to Interpro domains IPR001636 (SAICAR synthetase), IPR000031 (1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase), IPR013816 (ATP-grasp fold, subdomain 2)
25	sur-5	K03A1.5	n/a	chrX 7,303,412	sur-5 encodes a protein with high similarity to H. sapiens Acetoacetyl-coenzyme A synthetase; sur-5 negatively regulates let-60 during vulval induction, based on genetic analysis, and genetically synergises with lin-45 with respect to larval death, uncoordinated movement and egg-laying defects; sur-5 is strongly expressed in most cells of C. elegans, including the VPCs and is localized primarily to the nucleus.
26	K05F1.10	K05F1.10	n/a	chrII 5,805,057	K05F1.10 encodes a putative secreted TIL-domain protease inhibitor paralogous to SWM-1, ISL-1, and the products of 11 other C. elegans genes; K05F1.10 and its relatives are collectively similar to other TIL-domain protease inhibitors from nematodes, insects, and vertebrates; although it has no obvious function in mass RNAi assays, K05F1.10 transcription is reproducibly induced by infection, suggesting that it may participate in innate immunity.
27	nuo-1	C09H10.3	n/a	chrII 11,099,005	nuo-1 encodes a encodes a 51 kDa subunit of mitochondrial complex I that is required for oxidative phosphorylation, resistance to volatile anesthetics, and progression through development; nuo-1 is orthologous to human NDUFV1 (OMIM:161015, mutated in Leigh syndrome); nuo-1(ua1) induces a developmental arrest at the third larval (L3) stage that blocks reproduction, and thus is lethal to a population homozygous for nuo-1(ua1); yet arrested L3 nuo-1(ua1) animals have an individual lifespan significantly longer than normal.
28	R13H4.3	R13H4.3	n/a	chrV 11,834,560	contains similarity to Pfam domain PF00328 Histidine acid phosphatase contains similarity to Interpro domain IPR000560 (Histidine acid phosphatase)
29	F55E10.6	F55E10.6	n/a	chrX 8,345,470	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR003560 (2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
30	dhs-20	F35B12.2	n/a	chrV 11,603,237	dhs-20 encodes a short-chain dehydrogenase predicted to be mitochondrial.
31	lys-6	F58B3.3	n/a	chrIV 11,627,398	C. elegans LYS-6 protein; contains similarity to Pfam domain PF01183 Glycosyl hydrolases family 25 contains similarity to Interpro domains IPR017853 (Glycoside hydrolase, catalytic core), IPR013781 (Glycoside hydrolase, subgroup, catalytic core), IPR002053 (Glycoside hydrolase, family 25)
32	F44B9.2	F44B9.2	n/a	chrIII 8,023,742	contains similarity to Interpro domain IPR000694 (Proline-rich region)
33	C44C8.3	C44C8.3	n/a	chrIV 896,078	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
34	dpy-20	T22B3.1	n/a	chrIV 11,698,305	dpy-20 encodes a BED zinc finger protein, with no known homologs outside of nematodes, that is required for normal body morphology.
35	ptr-14	R09H10.4	n/a	chrIV 10,618,200	ptr-14 encodes a nematode-specific member of the sterol sensing domain (SSD) proteins, distantly paralogous to Drosophila PATCHED (PTC) and human PTCH (OMIM:601309, mutated in basal cell nevus syndrome); PTR-14 is weakly required for normal molting from L4 to adult stages; PTR-14 is also required for normal growth to full size and locomotion.
36	ugt-21	C33A12.6	n/a	chrIV 9,501,385	C. elegans UGT-21 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
37	H23N18.4	H23N18.4	n/a	chrV 4,902,178	contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
38	pcp-2	F23B2.12	n/a	chrIV 9,162,862	C. elegans PCP-2 protein; contains similarity to Pfam domain PF05577 Serine carboxypeptidase S28 contains similarity to Interpro domains IPR008758 (Peptidase S28), IPR000258 (Bacterial ice-nucleation proteins octamer repeat)
39	lgc-50	T20B12.9	n/a	chrIII 7,393,409	C. elegans LGC-50 protein; contains similarity to Pfam domains PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) , PF02932 (Neurotransmitter-gated ion-channel transmembrane region) contains similarity to Interpro domains IPR002289 (Gamma-aminobutyric-acid A receptor, beta subunit), IPR006028 (Gamma-aminobutyric acid A receptor), IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding), IPR006029 (Neurotransmitter-gated ion-channel transmembrane region)
40	C44C8.1	C44C8.1	n/a	chrIV 904,383	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
41	gst-42	D1053.1	n/a	chrX 11,727,007	gst-42 is orthologous to the human gene GLUTATHIONE TRANSFERASE ZETA-1 (also known as MALEYLACETOACETATE ISOMERASE; GSTZ1; OMIM:603758), which when mutated is thought to lead to a variety of type I tyrosinemia.
42	cyp-35B1	K07C6.4	n/a	chrV 3,940,140	C. elegans CYP-35B1 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
43	K07G5.5	K07G5.5	n/a	chrI 7,171,105	contains similarity to Pfam domain PF01545 Cation efflux family contains similarity to Interpro domain IPR002524 (Cation efflux protein)
44	Y43C5A.2	Y43C5A.2	n/a	chrIV 10,271,258	contains similarity to Pfam domain PF00147 Fibrinogen beta and gamma chains, C-terminal globular domain contains similarity to Interpro domains IPR013048 (Meiotic recombination Spo11), IPR014716 (Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1), IPR002181 (Fibrinogen, alpha/beta/gamma chain, C-terminal globular)
45	Y54G11A.7	Y54G11A.7	n/a	chrII 14,298,367	contains similarity to Interpro domains IPR011990 (Tetratricopeptide-like helical), IPR003006 (Immunoglobulin/major histocompatibility complex, conserved site), IPR000023 (Phosphofructokinase)
46	spp-4	T08A9.8	n/a	chrX 7,318,473	C. elegans SPP-4 protein; contains similarity to Pfam domain PF03489 Saposin-like type B, region 2 contains similarity to Interpro domains IPR008138 (Saposin-like type B, 2), IPR011001 (Saposin-like), IPR008373 (Saposin), IPR008139 (Saposin B)
47	C29F7.2	C29F7.2	n/a	chrX 13,417,071	contains similarity to Pfam domains PF02958 (Domain of unknown function (DUF227)) , PF07914 (Protein of unknown function (DUF1679)) contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species), IPR004119 (Protein of unknown function DUF227), IPR015897 (CHK kinase-like)
48	ugt-1	AC3.7	n/a	chrV 10,396,677	C. elegans UGT-1 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
49	K04A8.1	K04A8.1	n/a	chrV 6,567,604	contains similarity to Pfam domain PF03269 Caenorhabditis protein of unknown function, DUF268 contains similarity to Interpro domain IPR004951 (Protein of unknown function DUF268, Caenorhabditis species)
50	tag-197	F08C6.3	n/a	chrX 7,566,676	C. elegans TAG-197 protein; contains similarity to Pfam domain PF04129 Vps52 / Sac2 family contains similarity to Interpro domain IPR007258 (Vps52/Sac2)