UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F59B8.2	F59B8.2	0	chrIV 9,439,991	contains similarity to Pfam domain PF00180 Isocitrate/isopropylmalate dehydrogenase contains similarity to Interpro domains IPR004790 (Isocitrate dehydrogenase NADP-dependent, eukaryotic), IPR001804 (Isocitrate/isopropylmalate dehydrogenase)
2	sra-25	T26E3.9	n/a	chrI 12,687,150	C. elegans SRA-25 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domains IPR003945 (NADH-plastoquinone oxidoreductase, chain 5), IPR000344 (Nematode chemoreceptor, Sra)
3	cyp-35C1	C06B3.3	n/a	chrV 13,897,551	C. elegans CYP-35C1 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV)
4	T25D3.2	T25D3.2	n/a	chrII 155,462	contains similarity to Mus musculus 39S ribosomal protein L28, mitochondrial precursor (L28mt) (MRP-L28).; SW:Q9D1B9
5	dap-3	C14A4.2	n/a	chrII 10,581,748	dap-3 is an ortholog of mammalian death-associated protein 3 (DAP3), a mitochondrial ribosomal protein that promotes apoptosis.
6	F11C1.3	F11C1.3	n/a	chrX 12,983,754	contains similarity to Pfam domain PF01130 CD36 family contains similarity to Interpro domain IPR002159 (CD36 antigen)
7	nud-1	F53A2.4	n/a	chrIII 13,341,947	nud-1 encodes the C. elegans ortholog of the Aspergillus nidulans nudC, which mediates nuclear migration along Aspergillus hyphae.
8	C18E9.5	C18E9.5	n/a	chrII 8,970,895	contains similarity to Turkey herpesvirus LORF11.; TR:Q9IBS2
9	eft-1	ZK328.2	n/a	chrIII 6,011,147	eft-1 encodes an elongation factor 2 (EF-2)-like protein; by homology, EFT-1 is predicted to function as a GTPase required for the elongation step of protein synthesis; loss of eft-1 activity via large-scale RNAi indicates that eft-1 is an essential gene required for embryonic development, reproduction, and the overall health of the animal; eft-1 mRNA is detectable at all stages of C. elegans development.
10	H19N07.1	H19N07.1	n/a	chrV 11,111,736	contains similarity to Pfam domains PF03143 (Elongation factor Tu C-terminal domain) , PF03144 (Elongation factor Tu domain 2) , PF00009 (Elongation factor Tu GTP binding domain) contains similarity to Interpro domains IPR000795 (Protein synthesis factor, GTP-binding), IPR004160 (Translation elongation factor EFTu/EF1A, C-terminal), IPR004161 (Translation elongation factor EFTu/EF1A, domain 2), IPR009001 (Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)
11	npp-15	C29E4.4	n/a	chrIII 7,930,950	C. elegans NPP-15 protein; contains similarity to Pfam domains PF08801 (Nup133 N terminal like) , PF04044 (Nup133 nucleoporin) contains similarity to Interpro domains IPR014908 (Nup133, N-terminal), IPR015943 (WD40/YVTN repeat-like), IPR007187 (Nucleoporin, Nup133-like, C-terminal)
12	tufm-2	C43E11.4	n/a	chrI 4,248,543	C. elegans TUFM-2 protein; contains similarity to Pfam domains PF03143 (Elongation factor Tu C-terminal domain) , PF03144 (Elongation factor Tu domain 2) , PF00009 (Elongation factor Tu GTP binding domain) contains similarity to Interpro domains IPR000795 (Protein synthesis factor, GTP-binding), IPR005225 (Small GTP-binding protein), IPR004160 (Translation elongation factor EFTu/EF1A, C-terminal), IPR004161 (Translation elongation factor EFTu/EF1A, domain 2), IPR009001 (Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)
13	nuo-1	C09H10.3	n/a	chrII 11,099,005	nuo-1 encodes a encodes a 51 kDa subunit of mitochondrial complex I that is required for oxidative phosphorylation, resistance to volatile anesthetics, and progression through development; nuo-1 is orthologous to human NDUFV1 (OMIM:161015, mutated in Leigh syndrome); nuo-1(ua1) induces a developmental arrest at the third larval (L3) stage that blocks reproduction, and thus is lethal to a population homozygous for nuo-1(ua1); yet arrested L3 nuo-1(ua1) animals have an individual lifespan significantly longer than normal.
14	E04A4.5	E04A4.5	n/a	chrIV 4,744,928	contains similarity to Pfam domain PF02466 Tim17/Tim22/Tim23 family contains similarity to Interpro domains IPR005678 (Mitochondrial import inner membrane translocase, subunit Tim17), IPR003397 (Mitochondrial import inner membrane translocase, subunit Tim17/22)
15	math-18	C40A11.1	n/a	chrII 2,154,617	C. elegans MATH-18 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
16	M03B6.1	M03B6.1	n/a	chrX 13,842,218
17	phb-2	T24H7.1	n/a	chrII 6,252,083	phb-2 encodes one of two subunits of the mitochondrial prohibitin complex; loss of phb-2 activity via RNAi indicates that phb-2 function is required for mitochondrial biogenesis and maintenance and for embryonic, germline, and somatic gonad development.
18	gsto-1	C29E4.7	n/a	chrIII 7,946,235	gsto-1 encodes an experimentally verified thiol oxidoreductase and dehydroascorbate reductase, required for normal stress resistance; formally, GSTO-1 is an omega-class glutathione transferase (GST; EC 2.5.1.18), but it has little activity in vitro on classic GST substrates; GSTO-1 is expressed in postembryonic intestine; gsto-1(RNAi) induces hypersensitivity to heat-, arsenite-, juglone-, paraquat-, or cumene hydroperoxide-induced stresses, whereas overexpression of GSTO-1 enhances resistance to them; gsto-1 transcription is upregulated by stress; ELT-2 may directly activate gsto-1 transcription in developing gut via a 300-nucleotide sequence upstream of gsto-1's ATG start site.
19	F23B12.5	F23B12.5	n/a	chrV 14,446,285	F23B12.5 is orthologous to the human gene DIHYDROLIPOAMIDE DEHYDROGENASE (DLD; OMIM:109720), which when mutated leads to lactic acidosis due to lipoamide dehydrogenase deficiency; F23B12.5 protein is predicted to be mitochondrial.
20	tag-197	F08C6.3	n/a	chrX 7,566,676	C. elegans TAG-197 protein; contains similarity to Pfam domain PF04129 Vps52 / Sac2 family contains similarity to Interpro domain IPR007258 (Vps52/Sac2)
21	dnj-11	F38A5.13	n/a	chrIV 6,587,011	This gene encodes a protein containing a DnaJ ('J') domain.
22	sur-5	K03A1.5	n/a	chrX 7,303,412	sur-5 encodes a protein with high similarity to H. sapiens Acetoacetyl-coenzyme A synthetase; sur-5 negatively regulates let-60 during vulval induction, based on genetic analysis, and genetically synergises with lin-45 with respect to larval death, uncoordinated movement and egg-laying defects; sur-5 is strongly expressed in most cells of C. elegans, including the VPCs and is localized primarily to the nucleus.
23	tag-210	W08E3.3	n/a	chrI 13,342,122	C. elegans TAG-210 protein; contains similarity to Pfam domains PF01926 (GTPase of unknown function) , PF06071 (Protein of unknown function (DUF933)) contains similarity to Interpro domains IPR012675 (Beta-grasp fold, ferredoxin-type), IPR013029 (Protein of unknown function DUF933), IPR004396 (Conserved hypothetical protein CHP00092), IPR002917 (GTP-binding protein, HSR1-related), IPR012676 (TGS-like), IPR006073 (GTP1/OBG)
24	vrs-1	ZC513.4	n/a	chrV 8,033,348	vrs-1 encodes a predicted valyl-tRNA synthetase that affects embryonic viability, growth, and morphology
25	F59A3.3	F59A3.3	n/a	chrI 5,506,231	contains similarity to Pfam domain PF00467 KOW motif contains similarity to Interpro domains IPR005825 (Ribosomal protein L24/L26, conserved site), IPR008991 (Translation protein SH3-like), IPR005824 (KOW), IPR003256 (Ribosomal protein L24)
26	tin-13	DY3.1	n/a	chrI 8,759,490	C. elegans TIN-13 protein; contains similarity to Pfam domain PF02953 Tim10/DDP family zinc finger contains similarity to Interpro domain IPR004217 (Zinc finger, Tim10/DDP-type)
27	stdh-3	C06B3.5	n/a	chrV 13,905,299	stdh-3 encodes a putative steroid dehydrogenase orthologous to human HSD17B3 (OMIM:605573, mutated in pseudohermaphroditism), HSD17B12 (OMIM:609574), and HSDL1, and paralogous to LET-767, STDH-1/-2, and STDH-4; STDH-3 has no obvious function in mass RNAi assays.
28	gex-3	F28D1.10	n/a	chrIV 12,406,527	The gex-3 gene encodes a homolog of NAP1/NCKAP1, a mammalian protein ligand of the small GTPase Rac1, and of Drosophila HEM2/NAP1/KETTE; gex-3 is required for tissue morphogenesis and cell migrations; in gex-3 mutants, cells differentiate properly but fail to become organized.
29	ZK1236.1	ZK1236.1	n/a	chrIII 8,430,360	contains similarity to Pfam domains PF06421 (GTP-binding protein LepA C-terminus) , PF03144 (Elongation factor Tu domain 2) , PF00009 (Elongation factor Tu GTP binding domain) , PF00679 (Elongation factor G C-terminus) contains similarity to Interpro domains IPR003577 (Ras small GTPase, Ras type), IPR000795 (Protein synthesis factor, GTP-binding), IPR005225 (Small GTP-binding protein), IPR001806 (Ras GTPase), IPR004161 (Translation elongation factor EFTu/EF1A, domain 2), IPR006297 (GTP-binding protein LepA), IPR000640 (Translation elongation factor EFG/EF2, C-terminal), IPR013842 (GTP-binding protein LepA, C-terminal), IPR009022 (Elongation factor G, III and V)
30	xpo-3	C49H3.10	n/a	chrIV 7,920,396	imb-6 encodes an importin-beta-like protein orthologous to vertebrate Exportin-t, a specific mediator of tRNA export from the nucleus; IMB-6 is predicted to function by binding tRNAs directly in the presence of the RAN-1 GTPase and facilitating their nucleocytoplasmic transport; in C. elegans, loss of imb-6 function via RNA-mediated interference (RNAi) does not result in any obvious abnormalities.
31	C29F7.2	C29F7.2	n/a	chrX 13,417,071	contains similarity to Pfam domains PF02958 (Domain of unknown function (DUF227)) , PF07914 (Protein of unknown function (DUF1679)) contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species), IPR004119 (Protein of unknown function DUF227), IPR015897 (CHK kinase-like)
32	fbxa-64	T28A11.21	n/a	chrV 3,277,607	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
33	spt-5	K08E4.1	n/a	chrIV 12,053,606	C. elegans SPT-5 protein; contains similarity to Pfam domains PF03439 (Supt5 repeat) (2), PF00467 (KOW motif) contains similarity to Interpro domains IPR005100 (Supt5 repeat), IPR008991 (Translation protein SH3-like), IPR003257 (Transcription antitermination protein, NusG, archaea), IPR005824 (KOW), IPR017071 (Transcription elongation factor Spt5), IPR006645 (Transcription antitermination protein, NusG, N-terminal)
34	tag-264	B0511.8	n/a	chrI 10,637,866	C. elegans TAG-264 protein; contains similarity to Pfam domain PF07147 Mitochondrial 28S ribosomal protein S30 (PDCD9) contains similarity to Interpro domain IPR010793 (Ribosomal protein S30, mitochondrial)
35	cyp-13A11	F14F7.2	n/a	chrIII 13,022,359	C. elegans CYP-13A11 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002402 (Cytochrome P450, E-class, group II), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
36	T01E8.6	T01E8.6	n/a	chrII 10,241,373	contains similarity to Pfam domain PF00253 Ribosomal protein S14p/S29e contains similarity to Interpro domain IPR001209 (Ribosomal protein S14)
37	K06A5.6	K06A5.6	n/a	chrI 6,465,004	contains similarity to Pfam domains PF08028 (Acyl-CoA dehydrogenase, C-terminal domain) , PF02770 (Acyl-CoA dehydrogenase, middle domain) , PF00441 (Acyl-CoA dehydrogenase, C-terminal domain) , PF02771 (Acyl-CoA dehydrogenase, N-terminal domain) contains similarity to Interpro domains IPR013107 (Acyl-CoA dehydrogenase, type 2, C-terminal), IPR006090 (Acyl-CoA oxidase/dehydrogenase, type 1), IPR013786 (Acyl-CoA dehydrogenase/oxidase, N-terminal), IPR006091 (Acyl-CoA dehydrogenase/oxidase, central region), IPR006089 (Acyl-CoA dehydrogenase, conserved site), IPR013764 (Acyl-CoA oxidase/dehydrogenase, type1/2, C-terminal), IPR009100 (Acyl-CoA dehydrogenase/oxidase, middle and N-terminal), IPR006092 (Acyl-CoA dehydrogenase, N-terminal)
38	clec-56	F08H9.7	n/a	chrV 14,475,609	C. elegans CLEC-56 protein; contains similarity to Pfam domains PF00431 (CUB domain) (2), PF00059 (Lectin C-type domain) contains similarity to Interpro domains IPR000859 (CUB), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
39	T23B12.2	T23B12.2	n/a	chrV 8,468,082	contains similarity to Pfam domain PF00573 Ribosomal protein L4/L1 family contains similarity to Interpro domains IPR013005 (Ribosomal protein L4/L1e, bacterial-type), IPR002136 (Ribosomal protein L4/L1e)
40	C18E9.6	C18E9.6	n/a	chrII 8,972,695	contains similarity to Pfam domain PF01459 Eukaryotic porin contains similarity to Interpro domain IPR001925 (Porin, eukaryotic type)
41	T24C12.3	T24C12.3	n/a	chrX 2,200,203	contains similarity to Pfam domains PF00294 (pfkB family carbohydrate kinase) , PF04227 (Indigoidine synthase A like protein) contains similarity to Interpro domains IPR011611 (Carbohydrate/purine kinase), IPR002139 (Ribokinase), IPR007342 (Indigoidine synthase A like protein), IPR002173 (Carbohydrate/puine kinase, PfkB, conserved site)
42	rps-10	D1007.6	n/a	chrI 4,584,217	rps-10 encodes a small (40S) ribosomal subunit S10 protein; loss of rps-10 activity in adult animals extends lifespan.
43	F01G4.3	F01G4.3	n/a	chrIV 11,138,937	contains similarity to Pfam domains PF00270 (DEAD/DEAH box helicase) , PF08148 (DSHCT (NUC185) domain) , PF00271 (Helicase conserved C-terminal domain) contains similarity to Interpro domains IPR011545 (DNA/RNA helicase, DEAD/DEAH box type, N-terminal), IPR016438 (RNA helicase, ATP-dependent, SK12/DOB1), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR012961 (DSH, C-terminal), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
44	T08B1.1	T08B1.1	n/a	chrV 1,984,861	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR000817 (Prion protein), IPR005828 (General substrate transporter), IPR016196 (MFS general substrate transporter)
45	scpl-4	T21C9.12	n/a	chrV 10,600,600	scpl-4 encodes an ortholog of budding yeast TIM50 and human TIMM50 (OMIM:607381); by orthology, SCPL-4 is expected to be part of the mitochondrial inner membrane protein translocase; SCPL-4 is required for embryonic development and fertility in mass RNAi assays; SCPL-4 is distantly similar to FCP-1 and SCPL-1, -2, and -3.
46	lap-1	ZK353.6	n/a	chrIII 8,400,522	The lap-1 gene encodes a homolog of the zinc metalloprotease leucine aminopeptidase LAP that is predicted to be mitochondrial.
47	ZK1127.5	ZK1127.5	n/a	chrII 7,051,269	contains similarity to Pfam domains PF01137 (RNA 3'-terminal phosphate cyclase) , PF05189 (RNA 3'-terminal phosphate cyclase (RTC), insert domain) contains similarity to Interpro domains IPR016443 (RNA 3'-terminal phosphate cyclase-like, eukaryotic), IPR013796 (RNA 3'-terminal phosphate cyclase, insert region), IPR000228 (RNA 3'-terminal phosphate cyclase), IPR013792 (RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta)
48	C44B7.7	C44B7.7	n/a	chrII 6,879,653	contains similarity to Homo sapiens Uncharacterized protein C7orf24; ENSEMBL:ENSP00000275428
49	tsfm-1	F55C5.5	n/a	chrV 12,270,895	F55C5.5 encodes a translational elongation factor Ts (EF-Ts) that binds two different EF-Tu proteins (EF-TU1/Y71H2AM.23 and EF-TU2/C43E11.4) in vitro, stimulating guanine-nucleotide exchange and mRNA translation; F55C5.5 is predicted to be mitochondrial and has a putative N-terminal transit peptide sequence; F55C5.5 is required in mass RNAi assays for normally rapid growth and for maintenance of the germline.
50	K07G5.5	K07G5.5	n/a	chrI 7,171,105	contains similarity to Pfam domain PF01545 Cation efflux family contains similarity to Interpro domain IPR002524 (Cation efflux protein)