UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F59A6.3	F59A6.3	1e-47	chrII 5,009,745	contains similarity to Interpro domains IPR000436 (Sushi/SCR/CCP), IPR016060 (Complement control module)
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	C06G4.4	C06G4.4	n/a	chrIII 7,977,442
4	F22B3.8	F22B3.8	n/a	chrIV 11,423,572	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR000980 (SH2 motif), IPR008266 (Tyrosine protein kinase, active site)
5	C18H2.4	C18H2.4	n/a	chrIII 7,697,463	C18H2.4 is orthologous to the human gene GLOMULIN (FAP48; OMIM:601749), which when mutated leads to disease.
6	F57G4.5	F57G4.5	n/a	chrV 17,642,359	contains similarity to Mus musculus Dentin sialophosphoprotein precursor (Dentin matrix protein-3) (DMP-s3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP);sDentin sialoprotein (DSP)].; SW:DSPP_MOUSE
7	F48B9.3	F48B9.3	n/a	chrX 2,165,518	contains similarity to Pfam domain PF03761 Domain of unknown function (DUF316) contains similarity to Interpro domain IPR005514 (Protein of unknown function DUF316)
8	srz-1	F14F8.3	n/a	chrV 16,676,674	srz-1 encodes a predicted seven-pass G protein-coupled receptor; as loss of srz-1 activity via large-scale RNAi screens results in no obvious abnormalities, the precise role of SRZ-1 in C. elegans development and/or behavior is not yet known.
9	K04F1.8	K04F1.8	n/a	chrV 1,667,509
10	grl-22	W03A5.3	n/a	chrIII 5,413,566	grl-22 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central proline-rich low-complexity region, and a C-terminal Ground-like (Grl) domain; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
11	ZK666.2	ZK666.2	n/a	chrII 10,471,714	contains similarity to Homo sapiens ASH1; ENSEMBL:ENSP00000265206
12	T02H6.6	T02H6.6	n/a	chrII 683,947
13	F15D3.6	F15D3.6	n/a	chrI 11,574,794	contains similarity to Pfam domain PF04707 PRELI-like family contains similarity to Interpro domain IPR006797 (MSF1)
14	M03E7.3	M03E7.3	n/a	chrV 5,615,596
15	skr-20	R12H7.5	n/a	chrX 13,223,155	The skr-20 gene encodes a homolog of Skp1 in S. cerevisiae that has no known function in vivo, since skr-20(RNAi) animals are at least superficially normal.
16	C14B1.3	C14B1.3	n/a	chrIII 3,704,316	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
17	Y39A1A.18	Y39A1A.18	n/a	chrIII 10,692,438	contains similarity to Methanosarcina mazei Transcriptional regulator, MerR family.; TR:Q8PSB2
18	pat-10	F54C1.7	n/a	chrI 5,019,533	pat-10 encodes body wall muscle troponin C, the calcium-binding component of the troponin complex of actin thin filaments; PAT-10 is essential for muscle contraction and thus for completion of embryonic morphogenesis and elongation; by homology, PAT-10 likely functions to regulate body wall muscle contraction in response to changes in intracellular calcium; PAT-10 is expressed in body wall muscle but is also detected in vulval and anal muscles; expression in body wall muscle begins during early embryonic morphogenesis, concurrent with expression of other body wall muscle structural components.
19	B0207.1	B0207.1	n/a	chrI 5,966,138	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR000387 (Protein-tyrosine phosphatase), IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR000005 (Helix-turn-helix, AraC type), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000694 (Proline-rich region), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type)
20	T11G6.7	T11G6.7	n/a	chrIV 10,844,729	contains similarity to Fundulus heteroclitus Lens major intrinsic protein.; TR:Q9PUE2
21	tag-344	B0511.4	n/a	chrI 10,644,917	C. elegans TAG-344 protein; contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core)
22	col-64	F52F12.2	n/a	chrI 9,894,637	C. elegans COL-64 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (2)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR008161 (Collagen helix repeat), IPR008160 (Collagen triple helix repeat)
23	C34G6.1	C34G6.1	n/a	chrI 5,912,249	contains similarity to Pfam domain PF02985 HEAT repeat contains similarity to Interpro domains IPR011989 (Armadillo-like helical), IPR000357 (HEAT), IPR016024 (Armadillo-type fold)
24	C43D7.7	C43D7.7	n/a	chrV 19,319,210	contains similarity to Dictyostelium discoideum Filament-interacting protein.; TR:Q967Y0
25	F14E5.3	F14E5.3	n/a	chrII 8,436,197	contains similarity to Pfam domain PF00328 Histidine acid phosphatase contains similarity to Interpro domain IPR000560 (Histidine acid phosphatase)
26	T20D4.12	T20D4.12	n/a	chrV 3,397,421	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR002542 (Protein of unknown function DUF19)
27	B0457.4	B0457.4	n/a	chrII 8,911,392	contains similarity to Bacteriophage phi-C31 Gp21.; TR:Q9ZX87
28	W03F9.3	W03F9.3	n/a	chrV 132,775
29	C07H4.1	C07H4.1	n/a	chrII 9,091,587	contains similarity to Oceanobacillus iheyensis Hypothetical conserved protein.; TR:Q8ETI8
30	F01F1.3	F01F1.3	n/a	chrIII 5,873,818
31	C09D4.3	C09D4.3	n/a	chrI 5,489,487	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
32	twk-1	F21C3.1	n/a	chrI 7,270,700	C. elegans TWK-1 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR013099 (Ion transport 2)
33	T28D6.3	T28D6.3	n/a	chrIII 11,367,475	contains similarity to Arabidopsis thaliana Hypothetical protein LCR14 precursor.; TR:P82729
34	ZC8.6	ZC8.6	n/a	chrX 4,985,068	contains similarity to Pfam domain PF00454 Phosphatidylinositol 3- and 4-kinase contains similarity to Interpro domain IPR000403 (Phosphatidylinositol 3- and 4-kinase, catalytic)
35	ZK218.11	ZK218.11	n/a	chrV 17,107,962	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
36	C01H6.6	C01H6.6	n/a	chrI 7,223,298	C01H6.6 encodes a predicted transmembrane protein orthologous to human ACDP1-ACDP4 and S. cerevisiae MAM3, and paralogous to C33D12.2, C52D10.12, M02F4.3, R04E5.2, and R13G10.4; by orthology with MAM3, C01H6.6 may participate in metal homoeostasis; C01H6.6, MAM3, and ACDP1-ACDP4 belong to a family of proteins (sharing an ACD domain) from bacteria, yeast, plants, and metazoa; murine Acdp1 is a plasma membrane protein; bacterial proteins containing the ACD domain include CorC from Salmonella typhimurium, which is involved in magnesium and cobalt efflux; C01H6.6 has no obvious function in RNAi assays.
37	C08H9.13	C08H9.13	n/a	chrII 9,870,236	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR003624 (Leukemia inhibitory factor), IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)
38	C14A4.13	C14A4.13	n/a	chrII 10,619,389	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
39	Y43F8A.3	Y43F8A.3	n/a	chrV 19,379,196	contains similarity to Pfam domain PF07859 alpha/beta hydrolase fold contains similarity to Interpro domains IPR017157 (Arylacetamide deacetylase), IPR013094 (Alpha/beta hydrolase fold-3)
40	R07E5.6	R07E5.6	n/a	chrIII 4,399,849	contains similarity to Interpro domains IPR005432 (Gamma-aminobutyric-acid A receptor, alpha 2 subunit), IPR009149 (BR22)
41	W01B6.4	W01B6.4	n/a	chrIV 10,075,527	contains similarity to Interpro domains IPR008962 (PapD-like), IPR000173 (Glyceraldehyde 3-phosphate dehydrogenase)
42	F28A10.1	F28A10.1	n/a	chrII 826,849	F28A10.1 encodes a putative small-molecule methyltransferase, belonging to a large nematode-specific expanded family; F28A10.1 inhibits CEP-1- and HUS-1-dependent germline apoptosis, as do BMK-1, RAD-50, and RAD-51; F28A10.1 is expressed in neurons, and F28A10.1 transcripts are enriched in spermatogenesis; although F's obvious homologs are all Caenorhabditis proteins, it has distant similarity to 31-O-demethyl-FK506 methyltransferase (FkbM) from Streptomyces, to other bacterial FkbM homologs, and to other metazoan homologs such as human LOC728464.
43	F42G2.2	F42G2.2	n/a	chrII 2,423,776	contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
44	T01C3.5	T01C3.5	n/a	chrV 14,997,353	contains similarity to Oryza sativa Similar to gene for Pib.; TR:Q9LWW7
45	C34C12.4	C34C12.4	n/a	chrIII 3,468,832	contains similarity to Homo sapiens Uncharacterized protein C4orf34; ENSEMBL:ENSP00000295958
46	H05L14.1	H05L14.1	n/a	chrI 7,974,757	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR017442 (Serine/threonine protein kinase-related)
47	T12B3.4	T12B3.4	n/a	chrIV 7,386,993	contains similarity to Pfam domain PF03637 Mob1/phocein family contains similarity to Interpro domain IPR005301 (Mob1/phocein)
48	C33H5.16	C33H5.16	n/a	chrIV 7,802,511	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase)
49	R11E3.1	R11E3.1	n/a	chrIV 4,790,837	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR000980 (SH2 motif), IPR008266 (Tyrosine protein kinase, active site)
50	F25E2.2	F25E2.2	n/a	chrX 808,888	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)