UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	srm-3	F58G6.2	4.0000000000000004e-157	chrIV 9,649,830	C. elegans SRM-3 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	T01A4.3	T01A4.3	n/a	chrI 4,465,379	contains similarity to Pfam domain PF06918 Protein of unknown function (DUF1280) contains similarity to Interpro domain IPR009689 (Protein of unknown function DUF1280)
4	hlh-29	F31A3.4	n/a	chrX 17,548,141	C. elegans HLH-29 protein; contains similarity to Pfam domain PF00010 Helix-loop-helix DNA-binding domain contains similarity to Interpro domains IPR001092 (Basic helix-loop-helix dimerisation region bHLH), IPR011598 (Helix-loop-helix DNA-binding)
5	srj-22	F28H7.1	n/a	chrV 10,743,082	C. elegans SRJ-22 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
6	zyg-8	Y79H2A.11	n/a	chrIII 12,066,888	The zyg-8 gene encodes a protein with a doublecortin-like domain and a protein kinase domain; mutations of zyg-8 impair mitosis at the one-cell embryonic stage, which is normally asymmetrical, but which fails to show proper asymmetry in zyg-8 mutant embryos.
7	T02G5.11	T02G5.11	n/a	chrII 7,080,284	contains similarity to Pfam domain PF05741 Nanos RNA binding domain contains similarity to Interpro domain IPR008705 (Zinc finger, Nanos)
8	scm-1	M01D7.2	n/a	chrI 1,867,460	C. elegans SCM-1 protein; contains similarity to Pfam domain PF04144 SCAMP family contains similarity to Interpro domains IPR001395 (Aldo/keto reductase), IPR007273 (SCAMP)
9	srz-23	F58E2.9	n/a	chrIV 3,454,195	C. elegans SRZ-23 protein ;
10	srh-266	F31F4.6	n/a	chrV 665,362	C. elegans SRH-266 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
11	D2013.3	D2013.3	n/a	chrII 9,318,488	contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
12	nhr-181	F38H12.3	n/a	chrV 4,097,665	nhr-181 encodes a putative nuclear hormone receptor (NHR), belonging to a large nematode-specific expanded family of NHRs, that inhibits CEP-1- and HUS-1-dependent germline apoptosis as do BMK-1, RAD-50, and RAD-51.
13	C50F2.4	C50F2.4	n/a	chrI 3,890,325
14	C17E7.10	C17E7.10	n/a	chrV 3,899,486	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
15	B0511.5	B0511.5	n/a	chrI 10,630,197	contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domain IPR001507 (Endoglin/CD105 antigen)
16	Y49F6C.7	Y49F6C.7	n/a	chrII 3,367,722
17	gcy-23	T26C12.4	n/a	chrIV 3,286,107	gcy-23 encodes a receptor-type guanylyl cyclase that, along with gcy-8 and gcy-18, constitutes a subfamily of guanylyl cyclase genes in C. elegans; gcy-23 functions redundantly with gcy-8 and gcy-18, and upstream of tax-4, to regulate thermotaxis via the AFD thermosensory neurons, although of the three guanylyl cyclases required, genetic analyses suggest that GCY-18 is the primary guanylyl cyclase required; in addition, loss of gcy-23 activity via RNAi results in lifespan extension; GCY-23 is expressed exclusively in the AFD thermosensory neurons, where it localizes to sensory endings.
18	srd-44	F17A2.8	n/a	chrX 12,339,267	C. elegans SRD-44 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
19	mec-10	F16F9.5	n/a	chrX 8,467,984	The mec-10 gene encodes an amiloride-sensitive Na+ channel protein (degenerin) required to sense gentle mechanical stimuli (e.g. touch) along the body wall; it is paralogous to mec-4, which has similar function in vivo.
20	clec-195	Y116A8C.21	n/a	chrIV 17,044,558	C. elegans CLEC-195 protein; contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domains IPR006583 (CW), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
21	twk-20	C40C9.1	n/a	chrX 13,640,987	C. elegans TWK-20 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR013521 (Potassium channel, inwardly rectifying, Kir, conserved region 2), IPR003280 (Potassium channel, two pore-domain), IPR003938 (Potassium channel, voltage-dependent, EAG/ELK/ERG), IPR013099 (Ion transport 2), IPR003092 (Potassium channel, two pore-domain, TASK)
22	sri-31	B0454.2	n/a	chrII 3,051,657	C. elegans SRI-31 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
23	grl-6	K10C2.5	n/a	chrX 6,450,444	grl-6 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central proline-rich low-complexity region, and a C-terminal Ground-like (Grl) domain; GRL-6 is expressed in larval intestine, amphid socket cells, and neurons; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
24	F52C12.4	F52C12.4	n/a	chrIV 1,934,886	contains similarity to Pfam domains PF01535 (PPR repeat) , PF02141 (DENN (AEX-3) domain) , PF03456 (uDENN domain) , PF03455 (dDENN domain) contains similarity to Interpro domains IPR005112 (dDENN), IPR012336 (Thioredoxin-like fold), IPR005113 (uDENN), IPR002885 (Pentatricopeptide repeat), IPR001194 (DENN)
25	R05D7.5	R05D7.5	n/a	chrI 12,186,205	contains similarity to Ascaris suum P40.; TR:Q7YXJ9
26	apx-1	K08D9.3	n/a	chrV 3,216,670	apx-1 encodes one of ten C. elegans DSL (Delta, Serrate, LAG-2) proteins, integral transmembrane and secreted proteins that function as signaling ligands for the Notch family receptors GLP-1 and LIN-12; in the 4-cell embryo, maternally supplied APX-1 functions as a GLP-1 ligand for an inductive interaction that specifies the fate of the ABp blastomere; later in embryogenesis, APX-1 is required for formation of the LIN-12-dependent, invariant asymmetrical twist that occurs as part of normal gut morphogenesis; during larval development, APX-1 is required redundantly with DSL-1 and LAG-2 for the LIN-12-mediated lateral signal that spatially patterns the primary and secondary vulval cell lineages; in the early embryo, APX-1 is first detected at the anterior edge of the P1 blastomere, with later expression visible in P2 at sites of contact with ABp, and in the cytoplasm of the EMS and P3 blastomeres; expression in the vulval precursor cells (VPCs) is detected in the primary VPC, P6.p, and its descendants; embryonic APX-1 expression is dependent upon PIE-1 activity, while later vulval expression is mediated by the Ras signaling pathway and the SUR-2 transcriptional cofactor.
27	E04A4.6	E04A4.6	n/a	chrIV 4,746,804	contains similarity to Homo sapiens Isoform 5 of Tectonic-1 precursor; ENSEMBL:ENSP00000380771
28	str-122	W03D2.10	0.0002	chrIV 4,067,151	C. elegans STR-122 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
29	F52B11.5	F52B11.5	n/a	chrIV 14,102,592	contains similarity to Clostridium perfringens Hypothetical protein CPE2159.; TR:Q8XIG1
30	T08G5.7	T08G5.7	n/a	chrV 14,044,675	contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR003656 (Zinc finger, BED-type predicted), IPR007087 (Zinc finger, C2H2-type)
31	C50H11.17	C50H11.17	n/a	chrV 3,097,908	contains similarity to Pfam domain PF03236 Domain of unknown function DUF263 contains similarity to Interpro domain IPR004920 (Protein of unknown function DUF263)
32	F55A4.4	F55A4.4	n/a	chrX 1,025,409	contains similarity to Pfam domain PF00035 Double-stranded RNA binding motif contains similarity to Interpro domains IPR001159 (Double-stranded RNA binding), IPR014720 (Double-stranded RNA-binding-like)
33	F09C11.1	F09C11.1	n/a	chrIV 543,658
34	srh-295	ZK1037.8	n/a	chrV 15,331,670	C. elegans SRH-295 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
35	F09E10.6	F09E10.6	n/a	chrX 1,496,339
36	sre-40	T05A7.8	n/a	chrII 4,682,734	C. elegans SRE-40 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
37	ZK1098.5	ZK1098.5	n/a	chrIII 9,526,211	ZK1098.5 encodes a unfamiliar protein that is individually dispensable for viability and gross morphology in RNAi assays, but is cotranscribed with ZK1098.1 and thus might act in concert with it.
38	Y43F8C.13	Y43F8C.13	n/a	chrV 19,691,051	contains similarity to Pfam domain PF01156 Inosine-uridine preferring nucleoside hydrolase contains similarity to Interpro domain IPR001910 (Inosine/uridine-preferring nucleoside hydrolase)
39	T26G10.3	T26G10.3	n/a	chrIII 9,413,048	contains similarity to Pfam domain PF01282 Ribosomal protein S24e contains similarity to Interpro domain IPR001976 (Ribosomal protein S24e)
40	nhr-268	K06B4.6	n/a	chrV 15,690,903	C. elegans NHR-268 protein
41	srbc-58	R09E12.2	n/a	chrV 776,135	C. elegans SRBC-58 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
42	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
43	ptr-13	K07C10.1	n/a	chrII 11,159,735	ptr-13 encodes a nematode-specific member of the sterol sensing domain (SSD) proteins, distantly paralogous to Drosophila PATCHED (PTC) and human PTCH (OMIM:601309, mutated in basal cell nevus syndrome); PTR-13 is weakly required for normal molting from L4 to adult stages; PTR-13 is also required for normal growth to full size and locomotion.
44	gcy-37	C54E4.3	n/a	chrIV 2,154,905	gcy-37 encodes a predicted soluble guanylyl cyclase that is expressed in four candidate sensory neurons connected to the pseudocoelom, URXL, URXR, AQR, and PQR; as loss of gcy-37 activity via RNA-mediated interference does not result in any abnormalities, the precise role of GCY-37 in C. elegans development and/or behavior is not yet known; GCY-37 expression in neurons connected to the pseudocoelom suggests, however, that GCY-37 may play a role in fluid homeostasis.
45	sul-1	K09C4.8	n/a	chrX 3,269,056	sul-1 encodes a member of the sulfatase family.
46	R10D12.7	R10D12.7	n/a	chrV 13,950,209	contains similarity to Pfam domain PF01679 Uncharacterized protein family UPF0057 contains similarity to Interpro domain IPR000612 (Protein of unknown function UPF0057)
47	K09H11.5	K09H11.5	n/a	chrV 5,728,063
48	Y39A1A.17	Y39A1A.17	n/a	chrIII 10,688,996	contains similarity to Interpro domain IPR001611 (Leucine-rich repeat)
49	Y7A5A.2	Y7A5A.2	n/a	chrX 15,772,148	contains similarity to Aquifex aeolicus Hypothetical protein AQ_372.; SW:Y372_AQUAE
50	T07D3.5	T07D3.5	n/a	chrII 886,263	contains similarity to Pfam domain PF06828 Fukutin-related contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR009644 (Fukutin-related)