UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	sdz-23	F58G4.4	3e-148	chrV 8,100,032	sdz-23 encodes a putatively secreted protein with a single EGF domain, with some similarity to LAG-2; sdz-23 begins to be expressed in the E blastomere of 8-cell embryos, and continues to be expressed solely in the E lineage througout embryogenesis; sdz-23 requires SKN-1 and WRM-1 for E lineage expression, and is a putative MED-1/2 target gene; sdz-23 is both activated by POP-1 (with SYS-1 as coactivator, in the E lineage) and repressed by POP-1 (in the MS lineage), while the dependence of sdz-23 on WRM-1 for E lineage expression is alleviated by loss of POP-1, indicating that WRM-1 switches POP-1 from repression to activation in the E lineage; sdz-23 requires SYS-1 for normal embryonic expression; SDZ-23 has no obvious function in mass RNAi assays.
2	str-13	C24B9.8	n/a	chrV 2,726,550	C. elegans STR-13 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
3	T04G9.1	T04G9.1	n/a	chrX 792,247	contains similarity to Pfam domain PF02178 AT hook motif contains similarity to Interpro domains IPR000637 (HMG-I and HMG-Y, DNA-binding), IPR000694 (Proline-rich region)
4	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
5	F15H9.1	F15H9.1	n/a	chrI 12,157,921	contains similarity to Pfam domain PF03761 Domain of unknown function (DUF316) contains similarity to Interpro domain IPR005514 (Protein of unknown function DUF316)
6	T20B6.1	T20B6.1	n/a	chrIII 2,898,031	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase)
7	C14A6.7	C14A6.7	n/a	chrV 18,167,965	contains similarity to Gallus gallus Stathmin 3 (SCG10-like protein) (Neuroplasticin-2).; SW:STN3_CHICK
8	K06B4.4	K06B4.4	n/a	chrV 15,669,604	contains similarity to Interpro domain IPR006025 (Neutral zinc metallopeptidases, zinc-binding region)
9	fbxa-129	F59A1.8	n/a	chrV 17,656,084	C. elegans FBXA-129 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
10	srh-79	C04F2.1	n/a	chrV 7,498,378	C. elegans SRH-79 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR000175 (Sodium:neurotransmitter symporter), IPR003002 (7TM chemoreceptor, subfamily 1)
11	ifta-2	T28F3.6	n/a	chrIV 17,301,376	ifta-2 encodes a ciliary protein, orthologous to human RABL5, that is required for normally short life span and dauer formation; IFTA-2 is expressed in amphid, labial, and phasmid ciliated sensory neurons; intracellularly, IFTA-2 resides in the bases and axonemes of cilia, colocalizing with DAF-2 and AGE-1; IFTA-2 may be either a cargo or a cargo-docking component of intraflagellar transport (IFT) by the IFT-B complex; ciliary basal localization of IFTA-2 is abolished by a T42N mutation predicted to lock ITFA-2 into an inactive, GDP-bound conformation; ifta-2(tm1724) mutants have abnormally long lifespans and constitutive dauer formation, perhaps because IFTA-2 regulates DAF-2 signalling from ciliated sensory neurons; IFTA-2 is not required for cilium assembly or IFT, nor is it required for chemosensation or osmosensation; the ciliary localization of IFTA-2 is conserved in RABL5; via an X-box in its promoter, ifta-2 is a candidate for direct regulation by DAF-19.
12	F55E10.2	F55E10.2	n/a	chrX 8,340,780
13	F18C5.4	F18C5.4	n/a	chrII 6,564,443	contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR001478 (PDZ/DHR/GLGF)
14	srg-51	Y40H7A.8	n/a	chrIV 15,139,977	C. elegans SRG-51 protein ;
15	F56H6.6	F56H6.6	n/a	chrI 12,295,311	contains similarity to Mus musculus N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferases(EC 2.4.1.149) (Poly-N-acetyllactosamine extension enzyme) (I-beta-s1,3-N-acetylglucosaminyltransferase) (iGnT) (UDP-GlcNAc:betaGal beta-s1,3-N-acetylglucosaminyltransferase 1).; SW:Q8BWP8
16	srbc-10	C18B10.2	n/a	chrV 7,492,430	C. elegans SRBC-10 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
17	srz-10	ZK1037.11	n/a	chrV 15,308,296	C. elegans SRZ-10 protein ;
18	ZK380.2	ZK380.2	n/a	chrX 1,633,167	contains similarity to Interpro domain IPR011072 (HR1 rho-binding repeat)
19	tkr-1	C38C10.1	n/a	chrIII 9,386,535	tkr-1 encodes a G protein-coupled receptor that is the C. elegans tachykinin-like neuropeptide receptor homolog; by homology, TKR-1 is predicted to function in modulation of excitatory neurotransmission; as loss of tkr-1 activity via RNAi results in moderate reduction of fat content, TKR-1 may play a specific role in regulating lipid metabolism; a tkr-1 reporter gene fusion is reportedly expressed in the socket cells of the deirid and post-deirid sensilla from the L2 larval stage through adulthood.
20	srj-8	T28A11.9	n/a	chrV 3,248,476	C. elegans SRJ-8 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
21	C29F5.5	C29F5.5	n/a	chrII 6,297,911
22	B0524.2	B0524.2	n/a	chrIII 1,896,968	contains similarity to Pfam domain PF01734 Patatin-like phospholipase contains similarity to Interpro domains IPR016035 (Acyl transferase/acyl hydrolase/lysophospholipase), IPR002641 (Patatin)
23	srt-48	Y41E3.15	n/a	chrIV 15,067,356	C. elegans SRT-48 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
24	F28B1.2	F28B1.2	n/a	chrV 17,047,282	contains similarity to Arabidopsis thaliana T12C22.10 protein.; TR:Q9LPE8
25	exp-1	H35N03.1	n/a	chrII 6,159,051	exp-1 encodes an excitatory, cation-selective GABA receptor; EXP-1 activity is essential for the enteric muscle contractions that are the third in a series of three independent muscle contractions controlling defecation, and when expressed in Xenopus oocytes, EXP-1 is capable of forming a cation-selective GABA receptor; a rescuing EXP-1::GFP reporter fusion is expressed in the intestinal and anal depressor muscles, where it localizes to regions consistent with the positions of neuromuscular junctions; expression is also observed in neurons, including PDA, RID, ADE, and SABD.
26	M28.4	M28.4	n/a	chrII 10,645,246	contains similarity to Homo sapiens Kinesin-like protein 2; ENSEMBL:ENSP00000324020
27	ZK177.3	ZK177.3	n/a	chrII 5,516,470	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
28	Y4C6B.3	Y4C6B.3	n/a	chrIV 5,335,043	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR001411 (Tetracycline resistance protein, TetB), IPR011701 (Major facilitator superfamily MFS-1), IPR002229 (Blood group Rhesus C/E and D polypeptide), IPR016196 (MFS general substrate transporter)
29	F54D12.2	F54D12.2	n/a	chrII 1,399,803	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domain IPR006583 (CW)
30	F45C12.9	F45C12.9	n/a	chrII 1,709,067	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
31	ins-39	F21E9.4	n/a	chrX 1,344,119	ins-39 encodes an insulin-like peptide.
32	C31G12.4	C31G12.4	n/a	chrV 18,177,707	contains similarity to Pfam domain PF00646 (F-box domain)
33	cyp-29A4	B0331.1	n/a	chrV 9,656,299	C. elegans CYP-29A4 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR002397 (Cytochrome P450, B-class), IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002402 (Cytochrome P450, E-class, group II), IPR002403 (Cytochrome P450, E-class, group IV)
34	R07C3.10	R07C3.10	n/a	chrII 910,744
35	srz-103	F14F8.4	n/a	chrV 16,678,452	C. elegans SRZ-103 protein; contains similarity to Interpro domain IPR001046 (Natural resistance-associated macrophage protein)
36	F09C6.3	F09C6.3	n/a	chrV 16,879,465	contains similarity to Saccharomyces cerevisiae DNA damage-responsive protein, expression is increased in response to heat-shock stress or treatments that produce DNA lesions; SGD:YMR173W
37	F35F10.12	F35F10.12	n/a	chrV 3,314,352	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR000694 (Proline-rich region), IPR000698 (Arrestin), IPR014752 (Arrestin, C-terminal), IPR011021 (Arrestin-like, N-terminal)
38	srsx-14	C39H7.5	n/a	chrIV 5,625,990	C. elegans SRSX-14 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
39	H04M03.11	H04M03.11	n/a	chrIV 5,883,356
40	C06C6.7	C06C6.7	n/a	chrV 15,993,879	contains similarity to Pfam domain PF02206 Domain of unknown function contains similarity to Interpro domain IPR003125 (Protein of unknown function WSN)
41	str-143	C09H5.4	n/a	chrV 8,068,920	C. elegans STR-143 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
42	F02H6.6	F02H6.6	n/a	chrIV 14,230,085	contains similarity to Interpro domain IPR000884 (Thrombospondin, type I)
43	ZC132.2	ZC132.2	n/a	chrV 4,311,620
44	C03C10.2	C03C10.2	n/a	chrIII 4,092,033	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
45	tbx-33	Y66A7A.8	n/a	chrIII 11,635,769	C. elegans TBX-33 protein; contains similarity to Pfam domain PF00907 T-box contains similarity to Interpro domains IPR008967 (p53-like transcription factor, DNA-binding), IPR001699 (Transcription factor, T-box)
46	srbc-3	F35F10.2	n/a	chrV 3,309,077	C. elegans SRBC-3 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
47	F40F11.4	F40F11.4	n/a	chrIV 11,590,249	contains similarity to Interpro domains IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR006210 (EGF), IPR001881 (EGF-like calcium-binding), IPR013032 (EGF-like region, conserved site)
48	nhr-119	K12H6.1	n/a	chrII 2,799,024	C. elegans NHR-119 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
49	C03H5.4	C03H5.4	n/a	chrII 375,541	contains similarity to Pfam domain PF00068 Phospholipase A2 contains similarity to Interpro domains IPR016090 (Phospholipase A2), IPR001211 (Phospholipase A2, eukaryotic), IPR013090 (Phospholipase A2, active site)
50	R107.2	R107.2	n/a	chrIII 9,044,850	contains similarity to Pfam domain PF01256 Carbohydrate kinase contains similarity to Interpro domain IPR000631 (Carbohydrate kinase)