UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F58E6.7	F58E6.7	2.0000000000000002e-29	chrV 9,756,752	contains similarity to Variola virus Protein A51.; SW:VA51_VARV
2	C29F7.3	C29F7.3	n/a	chrX 13,419,306	contains similarity to Pfam domain PF00406 Adenylate kinase contains similarity to Interpro domains IPR000764 (Uridine kinase), IPR000850 (Adenylate kinase), IPR006266 (UMP-CMP kinase), IPR011769 (Adenylate/cytidine kinase, N-terminal)
3	odc-1	K11C4.4	n/a	chrV 6,899,252	odc-1 encodes ornithine decarboxylase, the first enzyme of polyamine biosynthesis that catalyzes the conversion of ornithine to putrescine; ODC-1 is required for development when animals are deprived of exogenous polyamines, which are required for oogenesis and completion of embryogenesis; in addition,ODC-1 may contribute to male fertility; ODC-1 activity is detectable at all developmental stages, with highest levels observed in adults and L4 larvae.
4	erv-46	K09E9.2	n/a	chrX 15,615,388	C. elegans ERV-46 protein; contains similarity to Pfam domain PF07970 Protein of unknown function (DUF1692) contains similarity to Interpro domain IPR012936 (Protein of unknown function DUF1692)
5	F32A5.3	F32A5.3	n/a	chrII 7,234,327	contains similarity to Pfam domain PF00450 Serine carboxypeptidase contains similarity to Interpro domain IPR001563 (Peptidase S10, serine carboxypeptidase)
6	F20G2.2	F20G2.2	n/a	chrV 13,755,695	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
7	W04G3.5	W04G3.5	n/a	chrX 11,074,823	contains similarity to Pfam domain PF00156 Phosphoribosyl transferase domain contains similarity to Interpro domains IPR005946 (Phosphoribosyl pyrophosphokinase), IPR000836 (Phosphoribosyltransferase)
8	dct-18	F58G1.4	n/a	chrII 12,932,607	C. elegans DCT-18 protein; contains similarity to Interpro domain IPR000886 (Endoplasmic reticulum, targeting sequence)
9	B0238.11	B0238.11	n/a	chrV 5,270,093	contains similarity to Interpro domain IPR009071 (High mobility group box, HMG)
10	lpd-6	K09H9.6	n/a	chrI 3,146,111	lpd-6 encodes a predicted rRNA-binding protein that is orthologous to Drosophila Peter Pan and the Saccharomyces cerevisiae SSF1 and SSF2 proteins that are required for ribosomal large subunit maturation; loss of lpd-6 activity via RNAi indicates that, in C. elegans, LPD-6 is required for fat storage and for larval growth and development; based upon its similarity to yeast SSF1 and SSF2, LPD-6 is predicted to be a nucleolar protein.
11	M28.5	M28.5	n/a	chrII 10,658,303	contains similarity to Pfam domain PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family contains similarity to Interpro domains IPR004038 (Ribosomal protein L7Ae/L30e/S12e/Gadd45), IPR000948 (Ribosomal protein HS6), IPR004037 (Ribosomal protein L7Ae), IPR002415 (High mobility group-like nuclear protein)
12	ugt-33	C35A5.2	n/a	chrV 10,494,911	C. elegans UGT-33 protein; contains similarity to Pfam domains PF04101 (Glycosyltransferase family 28 C-terminal domain) , PF00201 (UDP-glucoronosyl and UDP-glucosyl transferase) contains similarity to Interpro domains IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase), IPR007235 (Glycosyl transferase, family 28, C-terminal)
13	gsto-1	C29E4.7	n/a	chrIII 7,946,235	gsto-1 encodes an experimentally verified thiol oxidoreductase and dehydroascorbate reductase, required for normal stress resistance; formally, GSTO-1 is an omega-class glutathione transferase (GST; EC 2.5.1.18), but it has little activity in vitro on classic GST substrates; GSTO-1 is expressed in postembryonic intestine; gsto-1(RNAi) induces hypersensitivity to heat-, arsenite-, juglone-, paraquat-, or cumene hydroperoxide-induced stresses, whereas overexpression of GSTO-1 enhances resistance to them; gsto-1 transcription is upregulated by stress; ELT-2 may directly activate gsto-1 transcription in developing gut via a 300-nucleotide sequence upstream of gsto-1's ATG start site.
14	W09D10.3	W09D10.3	n/a	chrIII 10,708,021	contains similarity to Pfam domain PF00542 Ribosomal protein L7/L12 C-terminal domain contains similarity to Interpro domains IPR013823 (Ribosomal protein L7/L12, C-terminal), IPR014719 (Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like), IPR008932 (Ribosomal protein L7/L12, oligomerisation)
15	nhx-2	B0495.4	n/a	chrII 7,692,262	nhx-2 encodes a sodium/proton exchanger expressed in the apical membranes of intestinal cells; NHX-2 is required for normally high growth rates, and for propagation or maintenance of the germline, NHX-2 is thought to prevent intracellular acidification by catalysing the electroneutral exchange of extracellular sodium for an intracellular proton.
16	eft-1	ZK328.2	n/a	chrIII 6,011,147	eft-1 encodes an elongation factor 2 (EF-2)-like protein; by homology, EFT-1 is predicted to function as a GTPase required for the elongation step of protein synthesis; loss of eft-1 activity via large-scale RNAi indicates that eft-1 is an essential gene required for embryonic development, reproduction, and the overall health of the animal; eft-1 mRNA is detectable at all stages of C. elegans development.
17	K11D12.5	K11D12.5	n/a	chrV 5,030,085	contains similarity to Pfam domain PF03083 MtN3/saliva family contains similarity to Interpro domains IPR001411 (Tetracycline resistance protein, TetB), IPR004316 (MtN3 and saliva related transmembrane protein)
18	nhr-261	C49D10.9	n/a	chrII 3,863,911	C. elegans NHR-261 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
19	F36H1.5	F36H1.5	n/a	chrIV 11,030,632	contains similarity to Agrobacterium tumefaciens Hypothetical protein Atu4002.; TR:Q8U8T6
20	pabp-2	C17E4.5	n/a	chrI 9,421,408	pabp-2 encodes the C. elegans PABPN1 (polyadenylate-binding protein, nuclear 1) ortholog; by homology, PABP-2 is predicted to function as a poly(A)-binding protein involved in several aspects of pre-mRNA processing; large-scale RNAi screens indicate that pabp-2 activity is essential for embryonic and larval development, as well as normal rates of growth and locomotion; in humans, expansion of a polyalanine repeat in PABPN1 is associated with oculopharyngeal muscular dystrophy (OPMD, OMIM:602279).
21	D1025.2	D1025.2	n/a	chrX 14,514,552	contains similarity to Pfam domain PF01597 Glycine cleavage H-protein contains similarity to Interpro domains IPR017453 (Glycine cleavage H-protein, subgroup), IPR011053 (Single hybrid motif), IPR002930 (Glycine cleavage H-protein)
22	ugt-63	C04F5.7	n/a	chrV 5,109,468	C. elegans UGT-63 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
23	tag-267	W06E11.2	n/a	chrIII 641,164	C. elegans TAG-267 protein ;
24	K06A4.5	K06A4.5	n/a	chrV 9,506,309	contains similarity to Pfam domain PF06052 3-hydroxyanthranilic acid dioxygenase contains similarity to Interpro domains IPR011051 (Cupin, RmlC-type), IPR016700 (3-hydroxyanthranilate 3, 4-dioxygenase, metazoan), IPR010329 (3-hydroxyanthranilic acid dioxygenase)
25	erd-2	F09B9.3	n/a	chrX 10,158,581	erd-2 encodes a protein with homology to human ER lumen protein retaining receptor 1.
26	hke-4.2	H13N06.5	n/a	chrX 15,506,879	C. elegans HKE-4.2 protein; contains similarity to Pfam domain PF02535 ZIP Zinc transporter contains similarity to Interpro domains IPR002395 (HMW kininogen), IPR003689 (Zinc/iron permease)
27	F25B4.6	F25B4.6	n/a	chrV 5,683,638	F25B4.6 is orthologous to the human gene 3-HYDROXY-3-METHYLGLUTARYL COA SYNTHASE (HMGCS2; OMIM:600234), which when mutated leads to disease.
28	clec-56	F08H9.7	n/a	chrV 14,475,609	C. elegans CLEC-56 protein; contains similarity to Pfam domains PF00431 (CUB domain) (2), PF00059 (Lectin C-type domain) contains similarity to Interpro domains IPR000859 (CUB), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
29	ife-2	R04A9.4	n/a	chrX 382,059	ife-2 encodes a translation initiation factor 4F, cap-binding subunit (eIF-4E); by homology, IFE-2 is predicted to function in cap-dependent mRNA translation initiation; loss of ife-2 activity in adult animals extends lifespan.
30	F36A2.3	F36A2.3	n/a	chrI 8,800,214	contains similarity to Pfam domain PF02615 Malate/L-lactate dehydrogenase contains similarity to Interpro domain IPR003767 (Malate/L-lactate dehydrogenase)
31	F48E3.3	F48E3.3	n/a	chrX 7,498,278	contains similarity to Pfam domain PF06427 UDP-glucose:Glycoprotein Glucosyltransferase contains similarity to Interpro domain IPR009448 (UDP-glucose:Glycoprotein Glucosyltransferase)
32	nhr-3	H01A20.1	n/a	chrX 14,559,886	nhr-3 encodes a member of the superfamily of nuclear receptors which is one of the most abundant class of transcriptional regulators; nuclear receptors have a well conserved DNA binding domain and a less conserved C-terminal ligand binding domain; nhr-3 has been identified and characterised as a gene affected by ethanol exposure in a microarray analysis of all C. elegans ORFs.
33	K02G10.3	K02G10.3	n/a	chrX 4,675,475	contains similarity to Rattus norvegicus Transmembrane protein 135.; SW:Q5U4F4
34	clec-17	E03H4.10	n/a	chrI 12,430,738	C. elegans CLEC-17 protein; contains similarity to Pfam domains PF00431 (CUB domain) , PF00059 (Lectin C-type domain) (2)contains similarity to Interpro domains IPR000859 (CUB), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
35	nol-5	W01B11.3	n/a	chrI 3,268,107	C. elegans NOL-5 protein; contains similarity to Pfam domains PF01798 (Putative snoRNA binding domain) , PF08060 (NOSIC (NUC001) domain) , PF08156 (NOP5NT (NUC127) domain) contains similarity to Interpro domains IPR012974 (NOP5, N-terminal), IPR005819 (Histone H5), IPR002687 (Pre-mRNA processing ribonucleoprotein, binding region), IPR012976 (NOSIC)
36	H06H21.3	H06H21.3	n/a	chrIV 4,811,443	contains similarity to Pfam domain PF01176 Translation initiation factor 1A / IF-1 contains similarity to Interpro domains IPR016027 (Nucleic acid-binding, OB-fold-like), IPR012340 (Nucleic acid-binding, OB-fold), IPR006196 (S1, IF1 type), IPR001253 (Eukaryotic initiation factor 1A (eIF-1A))
37	lbp-5	W02D3.7	n/a	chrI 6,731,777	lbp-5 encodes a predicted intracellular fatty acid binding protein (iFABP) that is most similar to the vertebrate muscle and heart FABPs; by homology, LBP-5 is predicted to function as an intracellular transporter for small hydrophobic molecules such as lipids and steroid hormones; loss of lbp-5 activity via large-scale RNAi screens indicates that, in C. elegans, LBP-5 is required for movement.
38	aqp-11	ZK525.2	n/a	chrIII 13,673,891	aqp-11 encodes a putative aquaporin with no function in mass RNAi assays, perhaps reflecting genetic redundancy with its paralogs AQP-9 and AQP-10; AQP-11 is orthologous to Drosophila CG12251 and human AQP11 (OMIM:609914), AQP12A (OMIM:609789), and AQP12B.
39	F35D11.4	F35D11.4	n/a	chrII 4,603,738	contains similarity to Pfam domain PF01928 CYTH domain contains similarity to Interpro domains IPR008172 (Adenylate cyclase), IPR008173 (Adenylyl cyclase CyaB)
40	ZK185.3	ZK185.3	n/a	chrIV 4,529,575	contains similarity to Interpro domain IPR016181 (Acyl-CoA N-acyltransferase)
41	F20G2.1	F20G2.1	n/a	chrV 13,752,929	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
42	M04C3.2	M04C3.2	n/a	chrV 19,447,361	contains similarity to Arabidopsis thaliana Putative SWI/SNF-related matrix-associated actin-dependent regulatorsof chromatin subfamily A member 3-like 3 (EC 3.6.1.-) (SMARCA3-likesprotein 3).; SW:Q9FIY7
43	C03H12.1	C03H12.1	n/a	chrX 15,692,830	contains similarity to Interpro domain IPR012336 (Thioredoxin-like fold)
44	F11C1.3	F11C1.3	n/a	chrX 12,983,754	contains similarity to Pfam domain PF01130 CD36 family contains similarity to Interpro domain IPR002159 (CD36 antigen)
45	lbp-7	T22G5.2	n/a	chrV 13,879,814	lbp-7 encodes a predicted intracellular fatty acid binding protein (iFABP) that is most similar to the vertebrate muscle and heart FABPs; by homology, LBP-7 is predicted to function as an intracellular transporter for small hydrophobic molecules such as lipids and steroid hormones; as loss of lbp-7 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of LBP-7 in C. elegans development and/or behavior is not yet known.
46	W08E3.2	W08E3.2	n/a	chrI 13,334,747	contains similarity to Interpro domain IPR004054 (Potassium channel, voltage dependent, Kv4.1)
47	acbp-3	F47B10.7	n/a	chrX 10,904,105	acbp-3 encodes an Acyl-CoA-binding protein; a deletion mutation, tm2924, that overlaps with the 5' region of acbp-3 has been reported to result in lethality and sterility.
48	cyp-35A3	K09D9.2	n/a	chrV 4,023,531	C. elegans CYP-35A3 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
49	dnj-13	F54D5.8	n/a	chrII 11,546,449	This gene encodes a protein containing a DnaJ ('J') domain.
50	M88.2	M88.2	n/a	chrIII 4,541,915	contains similarity to Aedes aegypti Mitochondrial ribosomal protein, S34, putative.; TR:Q17JQ1