UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F58B3.4	F58B3.4	0	chrIV 11,630,269	contains similarity to Rattus norvegicus ESF1 homolog (ABT1-associated protein).; SW:Q76MT4
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	T12B3.2	T12B3.2	n/a	chrIV 7,377,887	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005828 (General substrate transporter), IPR016196 (MFS general substrate transporter)
4	ran-3	C26D10.1	n/a	chrII 8,323,764	C. elegans RAN-3 protein; contains similarity to Interpro domains IPR009091 (Regulator of chromosome condensation/beta-lactamase-inhibitor protein II), IPR000408 (Regulator of chromosome condensation, RCC1)
5	nst-1	K01C8.9	n/a	chrII 8,281,963	nst-1 encodes a homolog of human GNL3 (OMIM:608011, nucleostemin) and GNL3L, and of S. cerevisiae NUG1; NST-1 may suppress tumorous growth in the germline; like PRO-1, -2, and -3, NST-1 is probably required for ribosome biogenesis, suggesting a link between biogenesis in the distal sheath and control of cell division in the germline; nucleostemin is a nucleolar protein found in stem cells that is required in quantitatively correct amounts (neither too little nor too much) for continued cell division and survival by stem cells or transformed cells; NST-1 is required in mass RNAi assays for normally rapid growth, larval viability, and normal body morphology and pigmentation.
6	ucp-4	K07B1.3	n/a	chrV 9,335,690	C. elegans UCP-4 protein; contains similarity to Pfam domain PF00153 Mitochondrial carrier protein contains similarity to Interpro domains IPR002067 (Mitochondrial carrier protein), IPR002030 (Mitochondrial brown fat uncoupling protein), IPR001993 (Mitochondrial substrate carrier), IPR002113 (Adenine nucleotide translocator 1)
7	T19C3.1	T19C3.1	n/a	chrIII 608,506	contains similarity to Pfam domain PF01062 Bestrophin contains similarity to Interpro domain IPR000615 (Bestrophin)
8	R05D11.4	R05D11.4	n/a	chrI 8,599,872	contains similarity to Pfam domains PF00270 (DEAD/DEAH box helicase) , PF00271 (Helicase conserved C-terminal domain) contains similarity to Interpro domains IPR011545 (DNA/RNA helicase, DEAD/DEAH box type, N-terminal), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR014014 (RNA helicase, DEAD-box type, Q motif), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
9	R11D1.9	R11D1.9	n/a	chrV 12,729,002	contains similarity to Pfam domain PF05046 Mitochondrial large subunit ribosomal protein (Img2) contains similarity to Interpro domain IPR007740 (Ribosomal protein L49/IMG2)
10	R02F2.7	R02F2.7	n/a	chrIII 5,482,043
11	ZK1236.1	ZK1236.1	n/a	chrIII 8,430,360	contains similarity to Pfam domains PF06421 (GTP-binding protein LepA C-terminus) , PF03144 (Elongation factor Tu domain 2) , PF00009 (Elongation factor Tu GTP binding domain) , PF00679 (Elongation factor G C-terminus) contains similarity to Interpro domains IPR003577 (Ras small GTPase, Ras type), IPR000795 (Protein synthesis factor, GTP-binding), IPR005225 (Small GTP-binding protein), IPR001806 (Ras GTPase), IPR004161 (Translation elongation factor EFTu/EF1A, domain 2), IPR006297 (GTP-binding protein LepA), IPR000640 (Translation elongation factor EFG/EF2, C-terminal), IPR013842 (GTP-binding protein LepA, C-terminal), IPR009022 (Elongation factor G, III and V)
12	K01D12.6	K01D12.6	n/a	chrV 12,399,785	contains similarity to Homo sapiens Isoform 1 of Protein FAM73B; ENSEMBL:ENSP00000351138
13	C34B7.2	C34B7.2	n/a	chrI 8,339,396	contains similarity to Pfam domain PF02383 SacI homology domain contains similarity to Interpro domain IPR002013 (Synaptojanin, N-terminal)
14	T25B9.1	T25B9.1	n/a	chrIV 10,749,242	T25B9.1 encodes an protein highly similar to 2-amino-3-keto-butyrate coenzyme A ligases (also called AKB ligases or glycine acetyltransferases; EC 2.3.1.29; R.W.
15	C07H6.4	C07H6.4	n/a	chrIII 7,501,398	contains similarity to Pfam domains PF01805 (Surp module) , PF00076 (RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)) contains similarity to Interpro domains IPR006569 (Regulation of nuclear pre-mRNA protein), IPR000061 (SWAP/Surp), IPR012677 (Nucleotide-binding, alpha-beta plait), IPR008942 (ENTH/VHS), IPR000504 (RNA recognition motif, RNP-1)
16	R09B3.3	R09B3.3	n/a	chrI 11,910,664	contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR012677 (Nucleotide-binding, alpha-beta plait), IPR003954 (RNA recognition, region 1), IPR000504 (RNA recognition motif, RNP-1)
17	npp-14	C03D6.4	n/a	chrI 9,662,535	npp-14 is orthologous to the human gene NUCLEOPORIN, 214-KD (NUP214; OMIM:114350), which encodes part of the nucleopore complex mediating nucleocytoplasmic transport; NUP214, as a fusion gene with DEK (OMIM:125264), is found in a subset of acute myeloid leukemia.
18	R01H10.7	R01H10.7	n/a	chrIII 10,264,464	contains similarity to Interpro domain IPR001849 (Pleckstrin-like)
19	K07F5.14	K07F5.14	n/a	chrIV 9,863,121	contains similarity to Danio rerio Novel protein.; TR:Q1LV47
20	C24D10.6	C24D10.6	n/a	chrIV 5,159,856	contains similarity to Homo sapiens Coiled-coil-helix-coiled-coil-helix domain-containing protein 1; ENSEMBL:ENSP00000361923
21	C56G3.2	C56G3.2	n/a	chrX 7,365,880	contains similarity to Pfam domain PF00248 Aldo/keto reductase family contains similarity to Interpro domain IPR001395 (Aldo/keto reductase)
22	Y45G12C.4	Y45G12C.4	n/a	chrV 2,547,175	contains similarity to Pfam domains PF02958 (Domain of unknown function (DUF227)) , PF07914 (Protein of unknown function (DUF1679)) contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species), IPR004119 (Protein of unknown function DUF227), IPR015897 (CHK kinase-like)
23	mtr-4	W08D2.7	n/a	chrIV 9,828,133	C. elegans MTR-4 protein; contains similarity to Pfam domains PF00270 (DEAD/DEAH box helicase) , PF08148 (DSHCT (NUC185) domain) , PF00271 (Helicase conserved C-terminal domain) contains similarity to Interpro domains IPR011545 (DNA/RNA helicase, DEAD/DEAH box type, N-terminal), IPR002048 (Calcium-binding EF-hand), IPR016438 (RNA helicase, ATP-dependent, SK12/DOB1), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR012961 (DSH, C-terminal), IPR003593 (AAA+ ATPase, core), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
24	srsx-19	T22G5.4	n/a	chrV 13,888,537	C. elegans SRSX-19 protein; contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
25	D1043.1	D1043.1	n/a	chrII 11,585,601	contains similarity to Pfam domain PF02985 HEAT repeat contains similarity to Interpro domain IPR016024 (Armadillo-type fold)
26	F43C9.2	F43C9.2	n/a	chrX 4,788,190	contains similarity to Pfam domain PF00036 EF hand contains similarity to Interpro domains IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand), IPR008080 (Parvalbumin), IPR003299 (Flagellar calcium-binding protein (calflagin))
27	ZK856.10	ZK856.10	n/a	chrV 10,206,112	contains similarity to Pfam domains PF08292 (RNA polymerase III subunit Rpc25) , PF03876 (RNA polymerase Rpb7-like, N-terminal domain) contains similarity to Interpro domains IPR003029 (S1, RNA binding), IPR005576 (RNA polymerase Rpb7, N-terminal), IPR013238 (RNA polymerase III, subunit Rpc25)
28	T14B4.1	T14B4.1	n/a	chrII 6,739,132
29	CD4.8	CD4.8	n/a	chrV 5,600,286	contains similarity to Pfam domain PF04435 Domain of unknown function (DUF545) contains similarity to Interpro domain IPR006570 (SPK)
30	cua-1	Y76A2A.2	n/a	chrIII 13,447,397	The cua-1 gene encodes a putative E1-E2 ATPase orthologous to the human gene KIAA1347 (ATP7A; OMIM:604384), which when mutated leads to Hailey-Hailey disease.
31	C49A9.5	C49A9.5	n/a	chrIV 6,215,077	contains similarity to Pfam domain PF03312 Protein of unknown function, DUF272 contains similarity to Interpro domain IPR004987 (Protein of unknown function DUF272)
32	Y47D3B.9	Y47D3B.9	n/a	chrIII 11,467,116	contains similarity to Pfam domain PF02892 BED zinc finger contains similarity to Interpro domain IPR003656 (Zinc finger, BED-type predicted)
33	T27A8.3	T27A8.3	n/a	chrX 16,062,905	contains similarity to Pfam domain PF00557 metallopeptidase family M24 contains similarity to Interpro domains IPR000994 (Peptidase M24, catalytic core), IPR011991 (Winged helix repressor DNA-binding)
34	mrs-1	F58B3.5	n/a	chrIV 11,633,685	mrs-1 encodes a predicted cytoplasmic methionyl-tRNA synthetase (MetRS), a class I aminoacyl-tRNA synthetase that catalyzes the attachment of methionine to its cognate tRNA and is thus required for protein biosynthesis; MRS-1 is essential for embryogenesis and required also for a normal rate of postembryonic growth.
35	W06H3.3	W06H3.3	n/a	chrV 16,798,543	contains similarity to Pfam domains PF00117 (Glutamine amidotransferase class-I) , PF06418 (CTP synthase N-terminus) contains similarity to Interpro domains IPR000630 (Ribosomal protein S8), IPR017456 (CTP synthase, N-terminal), IPR000991 (Glutamine amidotransferase class-I, C-terminal), IPR004468 (CTP synthase), IPR012998 (Glutamine amidotransferase, class I, active site)
36	smp-2	D1037.2	n/a	chrI 3,669,414	C. elegans SMP-2 protein; contains similarity to Pfam domain PF01403 Sema domain contains similarity to Interpro domains IPR001627 (Semaphorin/CD100 antigen), IPR003659 (Plexin/semaphorin/integrin), IPR016201 (Plexin-like fold), IPR015943 (WD40/YVTN repeat-like)
37	C14B1.6	C14B1.6	n/a	chrIII 3,716,084	contains similarity to Interpro domain IPR008162 (Inorganic pyrophosphatase)
38	prp-17	F49D11.1	n/a	chrI 10,938,676	C. elegans PRP-17 protein; contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR011042 (Six-bladed beta-propeller, TolB-like), IPR015943 (WD40/YVTN repeat-like)
39	E02H1.6	E02H1.6	n/a	chrII 9,597,035	E02H1.6 encodes an ortholog of human TAF9 (OMIM:600822; also known as AK6, adrenal gland protein AD-004 like protein, ADLP) and of S. cerevisiae Fap7p; like its human ortholog, E02H1.6 is nuclear, and is predicted to likewise be a TATA box binding protein (TBP)-associated factor mediating activation of RNA polymerase II; E02H1.6 prefers ATP and dATP as phosphate donors; E02H1.6's biochemical activity is unusual, since it also prefers AMP and dAMP as substrates, and tolerates CMP, TMP and shikimate acid as substrates as well; since yeast Fap7p promotes pre-rRNA cleavage, E02H1.6 may be multifunctional; in RNAi assays, E02H1.6 is required for normally fast growth; E02H1.6 is coexpressed with pme-2 in an operon, and thus, like PME-2, may function in DNA repair.
40	cash-1	K07C5.8	n/a	chrV 10,364,141	cash-1 encodes an ortholog of Drosophila CKA and the human striatins STRN, STRN3, and STRN4 that is required for vulval development; CASH-1 has an N-terminal region which may bind caveolin or calmodulin, and a C-terminal region with five tandem WD domains; by its orthology with CKA and striatins, CASH-1 is predicted to act as a scaffold linking signal transduction proteins (such as JKK-1 and JNK-1) to transcription factors (such as JUN-1 or FOS-1); CASH-1 is expressed broadly, in both larval and adult pharynx, intestine, rectal epithelium, hypodermis, and neurons, as well as the developing vulva and the adult reproductive system.
41	tag-229	W09G3.3	n/a	chrI 13,804,628	C. elegans TAG-229 protein; contains similarity to Pfam domain PF08755 Hemimethylated DNA-binding protein YccV like contains similarity to Interpro domain IPR011722 (Hemimethylated DNA-binding region)
42	cyn-7	Y75B12B.2	n/a	chrV 15,186,997	cyn-7 encodes a cyclophilin A isoform; while not tested for peptidyl-prolyl isomerase activity in vitro, it is very similar to CYN-3 and closely resembles the prototypical CypA, and is therefore likely to be a member of the cytosolic CsA-binding cyclophilin subfamily; CYN-7 was required for embryonic viability in one set of mass RNAi assays.
43	C27A12.9	C27A12.9	n/a	chrI 6,064,908	contains similarity to Pfam domain PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase contains similarity to Interpro domains IPR017849 (Alkaline phosphatase-like, alpha/beta/alpha), IPR002591 (Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase), IPR017850 (Alkaline-phosphatase-like, core domain)
44	K02D10.4	K02D10.4	n/a	chrIII 8,778,867
45	C16C10.2	C16C10.2	n/a	chrIII 4,178,135	contains similarity to Pfam domain PF03998 Utp11 protein contains similarity to Interpro domain IPR007144 (Small-subunit processome, Utp11)
46	ZK1058.5	ZK1058.5	n/a	chrIII 3,921,159	contains similarity to Pfam domains PF08242 (Methyltransferase domain) , PF08241 (Methyltransferase domain) contains similarity to Interpro domains IPR017280 (Methyltransferase, METTL2, predicted), IPR013217 (Methyltransferase type 12), IPR013216 (Methyltransferase type 11)
47	R08D7.1	R08D7.1	n/a	chrIII 8,966,795	contains similarity to Drosophila pseudoobscura GA12417-PA (Fragment).; TR:Q293H8
48	F23H11.2	F23H11.2	n/a	chrIII 897,957	contains similarity to Interpro domains IPR001228 (4-diphosphocytidyl-2C-methyl-D-erythritol synthase), IPR002052 (N-6 adenine-specific DNA methylase, conserved site)
49	F33H2.2	F33H2.2	n/a	chrI 15,025,433	contains similarity to Homo sapiens Protein FAM91A1; ENSEMBL:ENSP00000335082
50	plc-4	R05G6.8	n/a	chrIV 7,511,060	C. elegans PLC-4 protein; contains similarity to Pfam domains PF00168 (C2 domain) , PF00387 (Phosphatidylinositol-specific phospholipase C, Y domain) , PF09279 (Phosphoinositide-specific phospholipase C, efhand-like) , PF00036 (EF hand) , PF00388 (Phosphatidylinositol-specific phospholipase C, X domain) contains similarity to Interpro domains IPR015359 (Phospholipase C, phosphoinositol-specific, EF-hand-like), IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand), IPR001192 (Phospholipase C, phosphoinositol-specific, C-terminal (PLC)), IPR001849 (Pleckstrin-like), IPR011993 (Pleckstrin homology-type), IPR000909 (Phospholipase C, phosphatidylinositol-specific , X region), IPR001711 (Phospholipase C, phosphatidylinositol-specific, Y domain), IPR013841 (Phospholipase C, phosphatidylinositol-specific , X and Y boxes), IPR000008 (C2 calcium-dependent membrane targeting)