UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	gpa-8	F56H9.3	0	chrV 12,639,639	gpa-8 encodes a member of the G protein alpha subunit family of heterotrimeric GTPases; expressed in URX, AQR, and PQR sensory cells.
2	C27H6.3	C27H6.3	n/a	chrV 9,981,996	contains similarity to Homo sapiens Acidic (Leucine-rich) nuclear phosphoprotein 32 family, member E; ENSEMBL:ENSP00000358111
3	lin-24	B0001.1	n/a	chrIV 12,132,269	lin-24 was identified in screens for mutations that result in altered vulval cell lineages; lin-24 is defined by two alleles, the first of which, a partially dominant mutation, generally results in vulvaless animals, while the second, a non-null amber mutation that is also partially dominant, results in wild-type animals when homozygous, but vulvaless animals when heterozygous with a wild-type allele; morphological examination of lin-24 animals indicates that some of the Pn.p cells that normally make up the vulva undergo inappropriate cell death that is dependent upon the ced-2, ced-5, and ced-10 engulfment genes, but not on the ced-3 and ced-4 killing genes; the precise molecular identity of lin-24 has not yet been reported.
4	nhr-273	T12C9.1	n/a	chrII 4,436,140	C. elegans NHR-273 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
5	cdh-6	F15B9.7	n/a	chrV 13,026,200	cdh-6 encodes a cadherin homolog, with a domain resembling seven transmembrane-sequence receptors, that may be orthologous to the Drosophila cadherin STAN; both CDH-6 and STAN are homologous to secretin-type receptors, have extracellular domains of similar lengths and domain compositions (with similar numbers of cadherin, EGF, laminin G, GFS, and HormR domains); however, the cytoplasmic domains of CDH-6 and STAN are dissimilar.
6	C25F6.6	C25F6.6	n/a	chrX 5,450,509
7	srbc-76	M01B2.4	n/a	chrV 15,252,812	C. elegans SRBC-76 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
8	srbc-45	ZC455.11	n/a	chrV 12,804,041	C. elegans SRBC-45 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
9	nhr-231	Y17D7B.1	n/a	chrV 18,792,886	C. elegans NHR-231 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
10	ugt-3	ZC455.3	n/a	chrV 12,799,239	C. elegans UGT-3 protein; contains similarity to Pfam domains PF04101 (Glycosyltransferase family 28 C-terminal domain) , PF00201 (UDP-glucoronosyl and UDP-glucosyl transferase) contains similarity to Interpro domains IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase), IPR007235 (Glycosyl transferase, family 28, C-terminal)
11	F57G4.6	F57G4.6	n/a	chrV 17,643,424	contains similarity to Interpro domains IPR013048 (Meiotic recombination Spo11), IPR006578 (MADF)
12	W06D11.4	W06D11.4	n/a	chrX 12,302,364	contains similarity to Pfam domain PF08123 Histone methylation protein DOT1 contains similarity to Interpro domain IPR013110 (Histone methylation DOT1)
13	srt-69	B0238.8	n/a	chrV 5,264,800	C. elegans SRT-69 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
14	C24H12.2	C24H12.2	n/a	chrII 437,796
15	aps-1	F29G9.3	n/a	chrV 6,018,404	aps-1 encodes an adaptin: specifically, it encodes an ortholog of the sigma1 subunit of adaptor protein complex 1 (AP-1).
16	polq-1	W03A3.2	n/a	chrIII 5,797,057	C. elegans POLQ-1 protein; contains similarity to Pfam domains PF00270 (DEAD/DEAH box helicase) , PF00476 (DNA polymerase family A) , PF00271 (Helicase conserved C-terminal domain) contains similarity to Interpro domains IPR011545 (DNA/RNA helicase, DEAD/DEAH box type, N-terminal), IPR001098 (DNA-directed DNA polymerase, family A), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR002298 (DNA polymerase A), IPR003593 (AAA+ ATPase, core), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
17	eif-3.C	T23D8.4	n/a	chrI 9,978,188	eif-3.C encodes a putative c subunit of translation initiation factor 3 that is required for fertility and for embryonic osmotic integrity; eif-3.C is orthologous to human EIF3S8 (OMIM:603916) and budding yeast NIP1.
18	C04F5.8	C04F5.8	n/a	chrV 5,112,623	contains similarity to Bos taurus Similar to C04F5.8.; TR:Q0IIF4
19	R186.3	R186.3	n/a	chrV 12,966,597	contains similarity to Interpro domains IPR006687 (GTP-binding protein SAR1), IPR005225 (Small GTP-binding protein), IPR001806 (Ras GTPase), IPR006688 (ADP-ribosylation factor), IPR003593 (AAA+ ATPase, core)
20	ZK1098.4	ZK1098.4	n/a	chrIII 9,543,651	contains similarity to Pfam domain PF01008 Initiation factor 2 subunit family contains similarity to Interpro domain IPR000649 (Initiation factor 2B related)
21	T07F10.5	T07F10.5	n/a	chrV 12,866,209	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domains IPR002168 (Lipase, GDXG, active site), IPR002018 (Carboxylesterase, type B)
22	K07C5.2	K07C5.2	n/a	chrV 10,340,201	contains similarity to Pfam domain PF00248 Aldo/keto reductase family contains similarity to Interpro domain IPR001395 (Aldo/keto reductase)
23	Y43F8C.7	Y43F8C.7	n/a	chrV 19,642,720	contains similarity to Anopheles gambiae str PEST AGAP011346-PA.; TR:Q7PST7
24	T09E11.1	T09E11.1	n/a	chrI 12,338,593	contains similarity to Pfam domain PF03360 Glycosyltransferase family 43 contains similarity to Interpro domain IPR005027 (Glycosyl transferase, family 43)
25	F42G8.6	F42G8.6	n/a	chrIV 8,131,368	contains similarity to Pfam domains PF05237 (MoeZ/MoeB domain) , PF00581 (Rhodanese-like domain) , PF00899 (ThiF family) contains similarity to Interpro domains IPR001763 (Rhodanese-like), IPR003016 (2-oxo acid dehydrogenase, lipoyl-binding site), IPR009036 (Molybdenum cofactor biosynthesis), IPR000594 (UBA/THIF-type NAD/FAD binding fold), IPR007901 (MoeZ/MoeB), IPR016040 (NAD(P)-binding)
26	srh-68	T21B4.5	n/a	chrII 12,507,810	C. elegans SRH-68 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR002379 (ATPase, F0/V0 complex, subunit C)
27	R10H10.6	R10H10.6	n/a	chrIV 10,409,131	contains similarity to Pfam domain PF01687 Riboflavin kinase contains similarity to Interpro domain IPR015865 (Riboflavin kinase)
28	asna-1	ZK637.5	n/a	chrIII 8,895,772	asna-1 encodes a putative membrane transporter that is required, non-cell-autonomously, for L1 larvae to proceed through development when fed, and is also required for normal insulin (DAF-28) secretion; the human ASNA1 ortholog stimulates insulin secretion in pancreatic beta cells, and can transgenically rescue asna-1 mutant C. elegans, suggesting that ASNA-1's function is conserved among metazoa; asna-1 mutants only progress to adulthood when rescued by maternal ASNA-1; without maternal rescue, asna-1 mutants eat food and endocytose nutrients normally, but nevertheless arrest growth as L1 larvae and localize DAF-16 to the nucleus as if food were absent; asna-1 is expressed in some sensory neurons, in insulin-producing intestinal cells, and in hypodermis; ASNA-1 positively regulates dauer exit in the same way that overexpression of the insulins DAF-28 or INS-4 does, and requires DAF-28 to do this efficiently; ASNA-1 has ATPase activity in vitro, and this activity is required for transgenic rescue of asna-1 mutations.
29	R09A8.1	R09A8.1	n/a	chrX 12,615,226	contains similarity to Homo sapiens FLASH; ENSEMBL:ENSP00000237177
30	exoc-7	C43E11.8	n/a	chrI 4,245,201	C. elegans EXOC-7 protein; contains similarity to Pfam domain PF03081 Exo70 exocyst complex subunit contains similarity to Interpro domain IPR004140 (Exo70 exocyst complex subunit)
31	F21D5.8	F21D5.8	n/a	chrIV 8,739,792	contains similarity to Homo sapiens 13 kDa protein; ENSEMBL:ENSP00000376734
32	Y116A8C.40	Y116A8C.40	n/a	chrIV 17,147,619	contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
33	E01G4.5	E01G4.5	n/a	chrII 13,473,085	contains similarity to Interpro domains IPR002345 (Lipocalin), IPR000215 (Protease inhibitor I4, serpin)
34	T03D3.5	T03D3.5	n/a	chrV 2,825,328
35	wht-4	F02E11.1	n/a	chrII 3,280,577	C. elegans WHT-4 protein; contains similarity to Pfam domains PF01061 (ABC-2 type transporter) , PF00005 (ABC transporter) contains similarity to Interpro domains IPR003439 (ABC transporter-like), IPR003593 (AAA+ ATPase, core), IPR005284 (Pigment precursor permease), IPR013525 (ABC-2 type transporter)
36	srd-2	R05H5.1	n/a	chrII 10,186,817	C. elegans SRD-2 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000276 (GPCR, rhodopsin-like), IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
37	str-193	C50C10.6	n/a	chrV 9,821,161	C. elegans STR-193 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
38	gfi-3	M163.4	n/a	chrX 14,482,535	gfi-3 is also known as apc-5, encoding a distant homolog of the human anaphase promoting complex subunit APC5, but is most closely related to its C. elegans paralog Y66D12A.17; gfi-3(RNAi) animals are generally unable to progress through meiotic divisions; initially they produce reduced numbers of viable embryos mixed with inviable embryos, but then show severe germline maintenance defects and become sterile.
39	T12A2.6	T12A2.6	n/a	chrIII 6,243,060
40	T20B5.2	T20B5.2	n/a	chrX 9,333,789
41	C32D5.10	C32D5.10	n/a	chrII 6,350,550	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
42	F43E2.1	F43E2.1	n/a	chrII 7,376,369
43	M04F3.2	M04F3.2	n/a	chrI 4,766,635	contains similarity to Bradyrhizobium japonicum 30S ribosomal protein S6.; SW:Q89MW3
44	pqn-8	C05B5.3	n/a	chrIII 9,996,987	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
45	C50E3.5	C50E3.5	n/a	chrV 7,591,348	contains similarity to Interpro domain IPR008108 (Type III secretion system outer membrane, B protein)
46	K02D10.5	K02D10.5	n/a	chrIII 8,777,270	contains similarity to Pfam domain PF05739 SNARE domain contains similarity to Interpro domain IPR000727 (Target SNARE coiled-coil region)
47	nhr-168	C50B6.8	n/a	chrV 13,332,476	C. elegans NHR-168 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
48	F09E5.12	F09E5.12	n/a	chrII 5,368,494	contains similarity to Pfam domain PF05001 RNA polymerase Rpb1 C-terminal repeat
49	tag-235	M03C11.4	n/a	chrIII 10,406,358	C. elegans TAG-235 protein; contains similarity to Interpro domain IPR016181 (Acyl-CoA N-acyltransferase)
50	srgp-1	F12F6.5	n/a	chrIV 11,574,575	C. elegans SRGP-1 protein; contains similarity to Pfam domains PF00620 (RhoGAP domain) , PF00611 (Fes/CIP4 homology domain) contains similarity to Interpro domains IPR001060 (Cdc15/Fes/CIP4), IPR008936 (Rho GTPase activation protein), IPR000198 (RhoGAP)