UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F56H1.5	F56H1.5	0	chrI 5,757,572	F56H1.5 encodes a putative ATP/ADP-activated metallocarboxypeptidase that may function in vivo as an alpha-tubulin C-terminal tyrosine carboxypeptidase; F56H1.5 is orthologous to murine AGTPBP-1/Nna1/pcd (upregulated in damaged mouse spinal cord and mutated in Purkinje cell degeneration) and human AGTPBP1 (OMIM:606830); murine AGTPBP-1 is genetically required for tubulin carboxypeptidase activity in vivo, and F56H1.5's nearest paralog EEED8.6 has biochemical traits consistent with tubulin carboxypeptidase activity; F56H1.5 and its mammalian AGTPBP1 orthologs, along with other proteins, comprise a M14D3 peptidase subfamily.
2	D1046.4	D1046.4	n/a	chrIV 8,935,680	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
3	dct-12	Y57A10C.7	n/a	chrII 12,431,464	C. elegans DCT-12 protein ;
4	acc-3	F55D10.5	n/a	chrX 4,725,216	C. elegans ACC-3 protein; contains similarity to Pfam domains PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) , PF02932 (Neurotransmitter-gated ion-channel transmembrane region) contains similarity to Interpro domains IPR001390 (Gamma-aminobutyric-acid A receptor, alpha subunit), IPR006028 (Gamma-aminobutyric acid A receptor), IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding), IPR006029 (Neurotransmitter-gated ion-channel transmembrane region)
5	M02B7.5	M02B7.5	n/a	chrIV 3,813,489	contains similarity to Pfam domains PF00612 (IQ calmodulin-binding motif) , PF01369 (Sec7 domain) contains similarity to Interpro domains IPR011993 (Pleckstrin homology-type), IPR000904 (SEC7-like)
6	ttr-40	E02C12.4	n/a	chrV 9,354,969	C. elegans TTR-40 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
7	F15H10.7	F15H10.7	n/a	chrV 10,404,755	contains similarity to Pfam domain PF02995 Protein of unknown function (DUF229) contains similarity to Interpro domains IPR004245 (Protein of unknown function DUF229), IPR017850 (Alkaline-phosphatase-like, core domain)
8	F35E12.8	F35E12.8	n/a	chrV 13,750,531	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domains IPR000859 (CUB), IPR003366 (CUB-like region)
9	ZK488.5	ZK488.5	n/a	chrV 594,476	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
10	C48B4.8	C48B4.8	n/a	chrIII 9,560,470	contains similarity to Bacillus subtilis Hypothetical protein ywcE precursor.; SW:YWCE_BACSU
11	nhr-72	C17A2.8	n/a	chrII 3,849,882	C. elegans NHR-72 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
12	K07E8.5	K07E8.5	n/a	chrII 652,962	K07E8.5 encodes a homolog of the functionally active Fmrf Receptor (FR; CG2114) of D. melanogaster; it is thus possible that K07E8.5 is a receptor for one of the FMRF-like neurotransmitters in C. elegans (e.g., FLP-1 through FLP-12).
13	F28B1.4	F28B1.4	n/a	chrV 17,056,226	contains similarity to Archaeoglobus fulgidus Ferredoxin (FDX-2).; TR:O30071
14	Y59C2A.2	Y59C2A.2	n/a	chrII 2,201,637	contains similarity to Interpro domain IPR000694 (Proline-rich region)
15	K03H1.8	K03H1.8	n/a	chrIII 9,945,970	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domain IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type)
16	T27A3.6	T27A3.6	n/a	chrI 6,106,790	T27A3.6 is orthologous to the human gene MOLYBDENUM COFACTOR BIOSYSTHESIS PROTEIN E (MOCS2; OMIM:603708), which when mutated leads to disease.
17	E02H4.2	E02H4.2	n/a	chrX 14,279,950	contains similarity to Homo sapiens Type-1 protein phosphatase skeletal muscle glycogen targeting subunit; ENSEMBL:ENSP00000284601
18	nhr-164	C41G6.5	n/a	chrV 15,234,803	C. elegans NHR-164 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
19	acl-2	T06E8.1	n/a	chrV 10,029,692	T06E8.1 is orthologous to the human gene 1-ACYLGLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE 2 (LYSOPHOSPHATIDIC ACID ACYLTRANSFERASE, BETA) (AGPAT2; OMIM:603100), which when mutated leads to disease; T06E8.1 protein is predicted to be mitochondrial.
20	sre-50	C50E10.11	n/a	chrII 12,304,243	C. elegans SRE-50 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
21	rab-10	T23H2.5	n/a	chrI 6,457,920	rab-10 encodes a Rab-like GTPase that is a member of the Ras superfamily of small GTPases; rab-10 activity is required, upstream of rme-1, for basolateral endocytic recycling in the intestine, but not in oocytes or coelomocytes; a RAB-10::GFP fusion protein is widely expressed and in the intestine, localizes to endosomes and the Golgi.
22	ZK593.8	ZK593.8	n/a	chrIV 10,938,663	contains similarity to Pfam domains PF07719 (Tetratricopeptide repeat) , PF02661 (Fic protein family) contains similarity to Interpro domains IPR003812 (Filamentation induced by cAMP protein Fic), IPR011990 (Tetratricopeptide-like helical), IPR013105 (Tetratricopeptide TPR2), IPR013026 (Tetratricopeptide region)
23	ced-5	C02F4.1	n/a	chrIV 10,488,503	The ced-5 gene a homolog of the human protein DOCK180 that is required for the cell engulfment stage of programmed cell death.
24	srh-46	T03F7.3	n/a	chrV 11,302,223	C. elegans SRH-46 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
25	C23H4.4	C23H4.4	n/a	chrX 12,231,444	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domains IPR008262 (Lipase, active site), IPR000062 (Thymidylate kinase), IPR002018 (Carboxylesterase, type B)
26	fbxb-13	C08F1.3	n/a	chrII 1,789,688	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
27	K09F6.7	K09F6.7	n/a	chrII 2,291,523	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR000315 (Zinc finger, B-box)
28	K02B2.6	K02B2.6	n/a	chrIV 5,961,963
29	str-60	T06C12.1	n/a	chrV 15,898,679	C. elegans STR-60 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
30	B0564.7	B0564.7	n/a	chrIV 13,102,647	contains similarity to Aedes aegypti Cell cycle progression.; TR:Q16U20
31	cyp-35B3	K07C6.2	n/a	chrV 3,946,183	C. elegans CYP-35B3 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
32	F49H6.12	F49H6.12	n/a	chrV 17,021,153	contains similarity to Phasianus colchicus Gag polyprotein (Fragment).; TR:Q9I9T0
33	M04C9.2	M04C9.2	n/a	chrI 9,347,132	contains similarity to Pfam domain PF06162 Caenorhabditis elegans protein of unknown function (DUF976) contains similarity to Interpro domains IPR010381 (Protein of unknown function DUF976, Caenorhabditis species), IPR016125 (Peptidase C15, pyroglutamyl peptidase I-like)
34	C26G2.2	C26G2.2	n/a	chrX 14,668,263	contains similarity to Drosophila melanogaster Flybase gene name is CG31439-PA;; FLYBASE:CG31439
35	Y20C6A.3	Y20C6A.3	n/a	chrV 17,382,699	contains similarity to Saccharomyces cerevisiae Myo1 is a type II myosin, is localized to the actomyosin ring and is important for cytokinesis.; SGD:YHR023W
36	F36G9.13	F36G9.13	n/a	chrV 15,984,973	contains similarity to Pfam domain PF02206 Domain of unknown function contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR003125 (Protein of unknown function WSN)
37	gcy-14	ZC412.2	n/a	chrV 14,865,514	gcy-14 encodes a predicted transmembrane guanylyl cyclase; the precise role of GCY-14 in C. elegans development and/or behavior is not yet known; however, by sequence similarity GCY-14 can be predicted to function in chemosensory signal transduction.
38	nhr-249	ZK381.3	n/a	chrIV 6,972,292	C. elegans NHR-249 protein; contains similarity to Pfam domain PF00104 Ligand-binding domain of nuclear hormone receptor contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
39	nth-1	R10E4.5	n/a	chrIII 4,292,462	C. elegans NTH-1 protein; contains similarity to Pfam domains PF00633 (Helix-hairpin-helix motif) , PF00730 (HhH-GPD superfamily base excision DNA repair protein) contains similarity to Interpro domains IPR011257 (DNA glycosylase), IPR003651 (Iron-sulphur cluster loop), IPR000445 (Helix-hairpin-helix motif), IPR004035 (Endonuclease III, iron-sulphur binding, conserved site-1), IPR004036 (Endonuclease III, conserved site-2), IPR003265 (HhH-GPD)
40	T20D4.9	T20D4.9	n/a	chrV 3,404,051	T20D4.9 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; T20D4.9 has no clear orthologs in other organisms.
41	sra-4	AH6.8	n/a	chrII 9,542,193	C. elegans SRA-4 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
42	T09E11.8	T09E11.8	n/a	chrI 12,351,698	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
43	T05H4.3	T05H4.3	n/a	chrV 6,444,929	contains similarity to Pfam domain PF00560 Leucine Rich Repeat contains similarity to Interpro domains IPR001611 (Leucine-rich repeat), IPR003591 (Leucine-rich repeat, typical subtype), IPR003603 (U2A'/phosphoprotein 32 family A, C-terminal)
44	C17A2.7	C17A2.7	n/a	chrII 3,842,652	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domains IPR004101 (Mur ligase, C-terminal), IPR002485 (Protein of unknown function DUF13)
45	srx-17	F55B12.8	n/a	chrV 13,841,443	C. elegans SRX-17 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
46	K09F5.1	K09F5.1	n/a	chrX 7,740,721
47	F10C2.7	F10C2.7	n/a	chrV 12,055,113	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
48	ZC487.3	ZC487.3	n/a	chrV 6,723,598
49	F57G4.9	F57G4.9	n/a	chrV 17,644,291	contains similarity to Xenopus laevis Putative uncharacterized protein.; TR:Q08AY0
50	srt-34	F54E2.6	n/a	chrV 2,817,549	C. elegans SRT-34 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)