UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	pes-2.2	F56G4.3	0	chrI 11,358,726	F56G4.3 encodes a protein that contains a predicted signal sequence, cyclin-like F box, and an F box-associated C-terminal domain; the protein product of F56G4.3 is identical to that of pes-2 and by homology, is predicted to function in ubiquitin-mediated protein degradation.
2	sra-25	T26E3.9	n/a	chrI 12,687,150	C. elegans SRA-25 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domains IPR003945 (NADH-plastoquinone oxidoreductase, chain 5), IPR000344 (Nematode chemoreceptor, Sra)
3	bra-2	F23H11.1	n/a	chrIII 911,744	The bra-2 gene encodes a homolog of the human BMP receptor-associated molecule (BRAM1), paralogous to bra-1, that may act upon the SMA-6 TGF-beta signalling pathway
4	skr-13	C52D10.8	n/a	chrIV 17,162,286	The skr-13 gene encodes a homolog of Skp1 in S. cerevisiae that has no known function in vivo, since skr-13(RNAi) animals are at least superficially normal.
5	pes-2.1	F56G4.2	0	chrI 11,355,795	pes-2 encodes a protein containing a predicted signal sequence and an F-box, a motif believed to mediate protein-protein interactions either with homologs of yeast Skp1p or with other proteins; pes-2 was identified in two different molecular screens, a promoter-trapping screen and a screen for genes that are preferentially transcribed in pre-gastrulation embryos; by homology, pes-2 is predicted to function in ubiquitin-proteasome mediated protein degradation; pes-2 may also play a role in lifespan determination, as its expression is downregulated in young adult worms containing loss-of-function mutations in the daf-2 insulin/IGF-1 receptor, and loss of pes-2 function via RNA-mediated interference (RNAi) can enhance animal survival rates; pes-2 expression is first detected in 4- to 8-cell stage embryos, continues in early embryogenesis in cells from the AB, MS, and E founder cell lineages, and in later embryogenesis is becomes restricted to hypodermal cells; expression in larvae and adults has not yet been reported.
6	clec-196	F26D10.12	n/a	chrIV 17,277,281	C. elegans CLEC-196 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
7	F28D1.2	F28D1.2	n/a	chrIV 12,375,385	contains similarity to Homo sapiens Myelin transcription factor 1; ENSEMBL:ENSP00000327465
8	sdz-25	M116.4	n/a	chrIV 8,405,798	C. elegans SDZ-25 protein; contains similarity to Pfam domains PF07735 (F-box associated) , PF00646 (F-box domain) contains similarity to Interpro domains IPR001810 (Cyclin-like F-box), IPR012885 (F-box associated type 2)
9	K02B12.2	K02B12.2	n/a	chrI 8,512,048	contains similarity to Interpro domain IPR008946 (Nuclear hormone receptor, ligand-binding)
10	F46E10.2	F46E10.2	n/a	chrV 6,520,674	contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR001030 (Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha)
11	B0304.2	B0304.2	n/a	chrII 4,524,073
12	skr-15	F54D10.1	n/a	chrII 3,824,456	The skr-15 gene encodes a homolog of Skp1 in S. cerevisiae that has no known function in vivo, since skr-15(RNAi) animals are at least superficially normal.
13	T05E7.5	T05E7.5	n/a	chrI 6,201,572	contains similarity to Trichomonas vaginalis G3 Viral A-type inclusion protein, putative.; TR:A2EJ43
14	F56A8.8	F56A8.8	n/a	chrIII 13,286,178	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8IHP7
15	T04B8.3	T04B8.3	n/a	chrII 628,093	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR011021 (Arrestin-like, N-terminal)
16	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
17	Y106G6D.1	Y106G6D.1	n/a	chrI 10,108,184	contains similarity to Methanocaldococcus jannaschii DNA double-strand break repair rad50 ATPase.; SW:Q58718
18	Y106G6D.2	Y106G6D.2	n/a	chrI 10,111,416	contains similarity to Homo sapiens hypothetical protein LOC283767; ENSEMBL:ENSP00000347269
19	sdz-33	Y56A3A.14	n/a	chrIII 11,907,882	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
20	ces-2	ZK909.4	n/a	chrI 14,963,425	ces-2 encodes a basic region leucine-zipper (bZIP) transcription factor, most similar in sequence and binding specificity to the PAR (proline- and acid-rich) subfamily of bZIP proteins; ces-2 is required to activate programmed cell death in the sister cells of the serotoninergic neurosecretory motor (NSM) neurons, and is transcriptionally inhibited by activated LET-60(G12V).
21	btb-6	F45C12.7	n/a	chrII 1,715,821	C. elegans BTB-6 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
22	fbxb-26	F58E1.3	n/a	chrII 1,683,034	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
23	sdz-22	F56F4.1	n/a	chrI 6,148,622	C. elegans SDZ-22 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
24	fbxb-84	T17A3.7	n/a	chrIII 146,002	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
25	Y43F11A.4	Y43F11A.4	n/a	chrII 12,120,633	contains similarity to Bos taurus Phosphatidylinositol 3-kinase regulatory gamma subunit (PI3-kinasesp85-gamma subunit) (PtdIns-3-kinase p85-gamma) (p55PIK).; SW:P55G_BOVIN
26	F48E3.6	F48E3.6	n/a	chrX 7,501,882
27	C47F8.7	C47F8.7	n/a	chrI 12,326,720
28	F38C2.5	F38C2.5	n/a	chrIV 16,278,575	F38C2.5 encodes a CCCH tandem zinc finger (TZF) protein; based upon its sequence similarity to C. elegans POS-1, the product of F38C2.5 is predicted to function as an RNA-binding protein.
29	fbxb-17	F58E1.5	n/a	chrII 1,676,856	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
30	sdz-28	R52.1	n/a	chrII 2,131,740	C. elegans SDZ-28 protein; contains similarity to Pfam domains PF00651 (BTB/POZ domain) , PF00917 (MATH domain) contains similarity to Interpro domains IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
31	C35D6.4	C35D6.4	n/a	chrIV 16,351,255	C35D6.4 encodes a CCCH tandem zinc finger (TZF) protein; based upon its sequence similarity to other TZF proteins, such as MEX-5 and POS-1, the product of C35D6.4 is predicted to function as an RNA-binding protein.
32	sea-1	F19B10.9	n/a	chrII 3,672,747	sea-1 encodes a T-box transcription factor; during development, sea-1 functions, zygotically and in a dose-dependent manner, as an autosomal element of the X:A (X chromosome:autosome) ratio that determines C. elegans sex; in opposition to the X signal elements, SEA-1 positively regulates transcription of xol-1, the master sex-determination switch gene that is essential for male development and for setting the proper activity level of the dosage compensation complex; consistent with its role as a regulator of sex determination, SEA-1 is expressed in nuclei of early embryos from approximately the 20- to 100-cell stage of embryogenesis.
33	fbxb-8	F49B2.1	n/a	chrI 14,302,931	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
34	C31H5.6	C31H5.6	n/a	chrI 9,045,096	contains similarity to Pfam domains PF08840 (BAAT / Acyl-CoA thioester hydrolase C terminal) , PF04775 (Acyl-CoA thioester hydrolase / Bile acid-CoA amino acid N-acetyltransferase) contains similarity to Interpro domains IPR006862 (Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase), IPR014940 (BAAT/Acyl-CoA thioester hydrolase C-terminal), IPR016662 (Acyl-CoA thioesterase, long chain)
35	fbxb-82	T17A3.4	n/a	chrIII 142,689	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
36	T24C4.2	T24C4.2	n/a	chrIII 868,674
37	C31H5.4	C31H5.4	n/a	chrI 9,042,426	contains similarity to Oryza sativa P0681F05.20 protein.; TR:Q8GVP7
38	cut-3	F22B5.3	n/a	chrII 8,445,930	C. elegans CUT-3 protein; contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domain IPR001507 (Endoglin/CD105 antigen)
39	fbxb-32	M151.6	n/a	chrII 3,646,198	C. elegans FBXB-32 protein; contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
40	fbxb-83	T17A3.6	n/a	chrIII 144,210	C. elegans FBXB-83 protein; contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
41	fbxb-66	Y40B1B.3	n/a	chrI 13,424,575	C. elegans FBXB-66 protein; contains similarity to Pfam domains PF07735 (F-box associated) , PF00646 (F-box domain) contains similarity to Interpro domains IPR001810 (Cyclin-like F-box), IPR012885 (F-box associated type 2)
42	bath-10	Y49F6C.4	n/a	chrII 3,375,923	C. elegans BATH-10 protein; contains similarity to Pfam domains PF00651 (BTB/POZ domain) , PF00917 (MATH domain) contains similarity to Interpro domains IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
43	ZK675.4	ZK675.4	n/a	chrII 7,911,649	contains similarity to Homo sapiens Nuclear pore glycoprotein p62; ENSEMBL:ENSP00000305503
44	F15B10.3	F15B10.3	n/a	chrIV 6,603,277	contains similarity to Interpro domain IPR016072 (SKP1 component, dimerisation)
45	R11.4	R11.4	n/a	chrX 16,210,394	contains similarity to Leishmania major Hypothetical protein.; TR:Q9GRL1
46	fbxb-54	K05F6.7	n/a	chrII 1,555,788	C. elegans FBXB-54 protein; contains similarity to Pfam domains PF07735 (F-box associated) , PF00646 (F-box domain) contains similarity to Interpro domains IPR001404 (Heat shock protein Hsp90), IPR001810 (Cyclin-like F-box), IPR012885 (F-box associated type 2)
47	ins-2	ZK75.2	n/a	chrII 5,988,821	ins-2 encodes an insulin-like peptide.
48	K08B4.2	K08B4.2	n/a	chrIV 6,075,712
49	skr-21	K08H2.1	n/a	chrX 13,226,159	The skr-21 gene encodes a homolog of Skp1 in S. cerevisiae that has no known function in vivo, since skr-21(RNAi) animals are at least superficially normal.
50	T12A2.3	T12A2.3	n/a	chrIII 6,241,137