UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	pes-2.1	F56G4.2	0	chrI 11,355,795	pes-2 encodes a protein containing a predicted signal sequence and an F-box, a motif believed to mediate protein-protein interactions either with homologs of yeast Skp1p or with other proteins; pes-2 was identified in two different molecular screens, a promoter-trapping screen and a screen for genes that are preferentially transcribed in pre-gastrulation embryos; by homology, pes-2 is predicted to function in ubiquitin-proteasome mediated protein degradation; pes-2 may also play a role in lifespan determination, as its expression is downregulated in young adult worms containing loss-of-function mutations in the daf-2 insulin/IGF-1 receptor, and loss of pes-2 function via RNA-mediated interference (RNAi) can enhance animal survival rates; pes-2 expression is first detected in 4- to 8-cell stage embryos, continues in early embryogenesis in cells from the AB, MS, and E founder cell lineages, and in later embryogenesis is becomes restricted to hypodermal cells; expression in larvae and adults has not yet been reported.
2	skr-13	C52D10.8	n/a	chrIV 17,162,286	The skr-13 gene encodes a homolog of Skp1 in S. cerevisiae that has no known function in vivo, since skr-13(RNAi) animals are at least superficially normal.
3	pes-2.2	F56G4.3	0	chrI 11,358,726	F56G4.3 encodes a protein that contains a predicted signal sequence, cyclin-like F box, and an F box-associated C-terminal domain; the protein product of F56G4.3 is identical to that of pes-2 and by homology, is predicted to function in ubiquitin-mediated protein degradation.
4	bra-2	F23H11.1	n/a	chrIII 911,744	The bra-2 gene encodes a homolog of the human BMP receptor-associated molecule (BRAM1), paralogous to bra-1, that may act upon the SMA-6 TGF-beta signalling pathway
5	K02B12.2	K02B12.2	n/a	chrI 8,512,048	contains similarity to Interpro domain IPR008946 (Nuclear hormone receptor, ligand-binding)
6	F28D1.2	F28D1.2	n/a	chrIV 12,375,385	contains similarity to Homo sapiens Myelin transcription factor 1; ENSEMBL:ENSP00000327465
7	skr-15	F54D10.1	n/a	chrII 3,824,456	The skr-15 gene encodes a homolog of Skp1 in S. cerevisiae that has no known function in vivo, since skr-15(RNAi) animals are at least superficially normal.
8	sra-25	T26E3.9	n/a	chrI 12,687,150	C. elegans SRA-25 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domains IPR003945 (NADH-plastoquinone oxidoreductase, chain 5), IPR000344 (Nematode chemoreceptor, Sra)
9	clec-196	F26D10.12	n/a	chrIV 17,277,281	C. elegans CLEC-196 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
10	sdz-25	M116.4	n/a	chrIV 8,405,798	C. elegans SDZ-25 protein; contains similarity to Pfam domains PF07735 (F-box associated) , PF00646 (F-box domain) contains similarity to Interpro domains IPR001810 (Cyclin-like F-box), IPR012885 (F-box associated type 2)
11	btb-6	F45C12.7	n/a	chrII 1,715,821	C. elegans BTB-6 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
12	T05E7.5	T05E7.5	n/a	chrI 6,201,572	contains similarity to Trichomonas vaginalis G3 Viral A-type inclusion protein, putative.; TR:A2EJ43
13	F46E10.2	F46E10.2	n/a	chrV 6,520,674	contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR001030 (Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha)
14	Y106G6D.1	Y106G6D.1	n/a	chrI 10,108,184	contains similarity to Methanocaldococcus jannaschii DNA double-strand break repair rad50 ATPase.; SW:Q58718
15	Y106G6D.2	Y106G6D.2	n/a	chrI 10,111,416	contains similarity to Homo sapiens hypothetical protein LOC283767; ENSEMBL:ENSP00000347269
16	sdz-22	F56F4.1	n/a	chrI 6,148,622	C. elegans SDZ-22 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
17	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
18	F56A8.8	F56A8.8	n/a	chrIII 13,286,178	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8IHP7
19	sea-1	F19B10.9	n/a	chrII 3,672,747	sea-1 encodes a T-box transcription factor; during development, sea-1 functions, zygotically and in a dose-dependent manner, as an autosomal element of the X:A (X chromosome:autosome) ratio that determines C. elegans sex; in opposition to the X signal elements, SEA-1 positively regulates transcription of xol-1, the master sex-determination switch gene that is essential for male development and for setting the proper activity level of the dosage compensation complex; consistent with its role as a regulator of sex determination, SEA-1 is expressed in nuclei of early embryos from approximately the 20- to 100-cell stage of embryogenesis.
20	C31G12.1	C31G12.1	n/a	chrV 18,180,590	contains similarity to Kaposi's sarcoma-associated herpesvirus K1 glycoprotein (Fragment).; TR:Q9WHA1
21	T04B8.3	T04B8.3	n/a	chrII 628,093	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR011021 (Arrestin-like, N-terminal)
22	fbxb-26	F58E1.3	n/a	chrII 1,683,034	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
23	rgs-8.1	F52D2.2	n/a	chrX 1,953,014	C. elegans RGS-8.1 protein; contains similarity to Interpro domains IPR016137 (Regulator of G protein signalling superfamily), IPR000342 (Regulator of G protein signalling)
24	sdz-33	Y56A3A.14	n/a	chrIII 11,907,882	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
25	cdc-25.3	ZK637.11	n/a	chrIII 8,917,082	cdc-25.3 encodes a tyrosine phosphatase that is a member of the cell division cycle 25 (CDC25) family of cell cycle regulators that includes Schizosaccharomyces pombe CDC25 and Drosophila string; cdc-25.3 is one of four cdc-25 genes in C. elegans and while it is known to be expressed in hermaphrodites, the precise function of cdc-25.3 is not yet clear; cdc-25.3 may function redundantly with cdc-25.2 during embryonic development and redundantly with cdc-25.1, cdc-25.2, and emb-29 during meiosis.
26	Y43F11A.4	Y43F11A.4	n/a	chrII 12,120,633	contains similarity to Bos taurus Phosphatidylinositol 3-kinase regulatory gamma subunit (PI3-kinasesp85-gamma subunit) (PtdIns-3-kinase p85-gamma) (p55PIK).; SW:P55G_BOVIN
27	fbxb-84	T17A3.7	n/a	chrIII 146,002	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
28	F48E3.6	F48E3.6	n/a	chrX 7,501,882
29	ces-2	ZK909.4	n/a	chrI 14,963,425	ces-2 encodes a basic region leucine-zipper (bZIP) transcription factor, most similar in sequence and binding specificity to the PAR (proline- and acid-rich) subfamily of bZIP proteins; ces-2 is required to activate programmed cell death in the sister cells of the serotoninergic neurosecretory motor (NSM) neurons, and is transcriptionally inhibited by activated LET-60(G12V).
30	F38C2.5	F38C2.5	n/a	chrIV 16,278,575	F38C2.5 encodes a CCCH tandem zinc finger (TZF) protein; based upon its sequence similarity to C. elegans POS-1, the product of F38C2.5 is predicted to function as an RNA-binding protein.
31	fbxb-17	F58E1.5	n/a	chrII 1,676,856	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
32	F53F8.3	F53F8.3	n/a	chrV 20,684,555	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
33	F14D7.2	F14D7.2	n/a	chrV 14,292,817	contains similarity to Homo sapiens Similar to Dentin sialophosphoprotein preproprotein; ENSEMBL:ENSP00000282478
34	C35D6.4	C35D6.4	n/a	chrIV 16,351,255	C35D6.4 encodes a CCCH tandem zinc finger (TZF) protein; based upon its sequence similarity to other TZF proteins, such as MEX-5 and POS-1, the product of C35D6.4 is predicted to function as an RNA-binding protein.
35	fbxb-82	T17A3.4	n/a	chrIII 142,689	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
36	fbxb-8	F49B2.1	n/a	chrI 14,302,931	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
37	T12G3.6	T12G3.6	n/a	chrIV 12,030,485	contains similarity to Helicobacter pylori Hypothetical protein HP1128.; TR:O25753
38	fbxb-83	T17A3.6	n/a	chrIII 144,210	C. elegans FBXB-83 protein; contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
39	fbxb-66	Y40B1B.3	n/a	chrI 13,424,575	C. elegans FBXB-66 protein; contains similarity to Pfam domains PF07735 (F-box associated) , PF00646 (F-box domain) contains similarity to Interpro domains IPR001810 (Cyclin-like F-box), IPR012885 (F-box associated type 2)
40	T12A2.3	T12A2.3	n/a	chrIII 6,241,137
41	H04M03.3	H04M03.3	n/a	chrIV 5,892,434	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
42	F15B10.3	F15B10.3	n/a	chrIV 6,603,277	contains similarity to Interpro domain IPR016072 (SKP1 component, dimerisation)
43	R11.4	R11.4	n/a	chrX 16,210,394	contains similarity to Leishmania major Hypothetical protein.; TR:Q9GRL1
44	C47F8.7	C47F8.7	n/a	chrI 12,326,720
45	C35D10.13	C35D10.13	n/a	chrIII 4,877,976
46	sdz-28	R52.1	n/a	chrII 2,131,740	C. elegans SDZ-28 protein; contains similarity to Pfam domains PF00651 (BTB/POZ domain) , PF00917 (MATH domain) contains similarity to Interpro domains IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
47	fbxb-54	K05F6.7	n/a	chrII 1,555,788	C. elegans FBXB-54 protein; contains similarity to Pfam domains PF07735 (F-box associated) , PF00646 (F-box domain) contains similarity to Interpro domains IPR001404 (Heat shock protein Hsp90), IPR001810 (Cyclin-like F-box), IPR012885 (F-box associated type 2)
48	T24C4.2	T24C4.2	n/a	chrIII 868,674
49	fbxb-3	F38H4.2	n/a	chrIV 11,839,582	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
50	F58E6.3	F58E6.3	n/a	chrV 9,748,618	contains similarity to Pfam domains PF00008 (EGF-like domain) (2), PF07699 (GCC2 and GCC3) (4)contains similarity to Interpro domains IPR000742 (EGF-like, type 3), IPR006209 (EGF-like), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR011641 (GCC2 and GCC3), IPR001881 (EGF-like calcium-binding), IPR009030 (Growth factor, receptor), IPR013032 (EGF-like region, conserved site)